LOCUS       NP_001360894             323 aa            linear   ROD 29-APR-2025
DEFINITION  transmembrane protein 171 isoform 1 [Mus musculus].
ACCESSION   NP_001360894 XP_006517772
VERSION     NP_001360894.1
DBSOURCE    REFSEQ: accession NM_001373965.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131187.4.
            
            On Sep 6, 2019 this sequence version replaced XP_006517772.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.85957.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 52.13 cM"
     Protein         1..323
                     /product="transmembrane protein 171 isoform 1"
                     /calculated_mol_wt=34610
     Region          2..318
                     /region_name="TMEM171"
                     /note="Transmembrane protein family 171; pfam15471"
                     /db_xref="CDD:464734"
     Site            22..42
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4KL18.1)"
     Site            57..77
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4KL18.1)"
     Site            112..132
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4KL18.1)"
     Site            159..179
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4KL18.1)"
     CDS             1..323
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /coded_by="NM_001373965.1:115..1086"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:380863"
                     /db_xref="MGI:MGI:2685751"
ORIGIN      
        1 mssvgtaepd gdqrdrhvsk lifflfvfga allcvgvlls ifgyqacqyk plshcsivlk
       61 iagpscavvg lgavilarsr arlhlrerqr qglqdpdqsf fcgesrqfaq clifgflflt
      121 sgmlisilgi wvpgcdsdwa qeplnetntg egepqicgfl slqimgplvv lvglcffvva
      181 hvkkknnlss srdtsevegg hahstepvhi tvgdsviifp pppppyfpes saaapspgan
      241 slhqienpps ysslfnygrt ptpenqgaas ereqeliyti sgqgsssers ytghlpldlp
      301 pryeeketap atplgapsda spp
//
