LOCUS       NM_001025606            1183 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 171 (Tmem171), transcript
            variant 2, mRNA.
ACCESSION   NM_001025606 XM_354769
VERSION     NM_001025606.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1183)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC099490.1.
            
            On Jul 21, 2005 this sequence version replaced XM_354769.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099490.1, SRR5189685.98810.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1183
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 52.13 cM"
     gene            1..1183
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /note="transmembrane protein 171"
                     /db_xref="GeneID:380863"
                     /db_xref="MGI:MGI:2685751"
     exon            1..26
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /inference="alignment:Splign:2.1.0"
     exon            27..740
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..1072
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="transmembrane protein 171 isoform 2"
                     /protein_id="NP_001020777.1"
                     /db_xref="CCDS:CCDS26716.1"
                     /db_xref="GeneID:380863"
                     /db_xref="MGI:MGI:2685751"
                     /translation="MSSVGTAEPDGDQRDRHVSKLIFFLFVFGAALLCVGVLLSIFGY
                     QACQYKPLSHCSIVLKIAGPSCAVVGLGAVILARSRARLHLRERQRQGLQDPDQSFFC
                     GESRQFAQCLIFGFLFLTSGMLISILGIWVPGCDSDWAQEPLNETNTGEGEPQICGFL
                     SLQIMGPLVVLVGLCFFVVAHVKKKNNLSSSRDTSEVEGGHAHSTEPVHITVGDSVII
                     FPPPPPPYFPESSAAAPSPGANSLHQIENPPSYSSLFNYGTPTPENQGAASEREQELI
                     YTISGQGSSSERSYTGHLPLDLPPRYEEKETAPATPLGAPSDASPP"
     exon            741..876
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /inference="alignment:Splign:2.1.0"
     exon            877..1155
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1138..1143
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /note="hexamer: AATAAA"
     polyA_site      1155
                     /gene="Tmem171"
                     /gene_synonym="Gm905"
                     /note="major polyA site"
ORIGIN      
        1 ggagagtccc aggaccagca gcgcagagcc tgcaactgct ggagggaagg aaacacattt
       61 cttcacatca gggaacaacg aggaggcctt ttcttttctg gccatgtctt ctgtaggaac
      121 tgctgagcca gatggagacc agagggaccg gcatgtcagc aagctcattt tcttcctctt
      181 tgtcttcggt gcagctctgt tgtgtgttgg ggtcctgctc tccatctttg ggtaccaggc
      241 atgccaatat aagcccctct cacactgcag catagtgctg aagattgctg ggccttcgtg
      301 tgcagtggtg ggccttgggg ctgtgattct ggcccggtcc cgggcacgcc tgcatctacg
      361 ggagcgacag cggcaaggcc ttcaggaccc tgaccaatcc ttcttctgtg gagagagccg
      421 ccagtttgcc cagtgtctca tctttgggtt cttgtttctg accagtggca tgctcattag
      481 catactgggc atttgggtgc caggatgtga ctcagattgg gcacaggaac cactgaatga
      541 gacaaacacc ggagaaggag aaccccagat ctgtggcttc ctttctctgc agatcatggg
      601 gcccttggtt gtgcttgtgg gactgtgttt ctttgtggtg gcccatgtta agaagaaaaa
      661 caacttgagt tcaagccgag atacctctga ggtcgaaggt ggacacgccc acagcacgga
      721 gcctgtccac atcactgtag gtgactcagt gataatcttc ccgccccctc caccacctta
      781 ctttcctgag tcttcagcag cggctccatc ccctggggct aacagcctgc accagattga
      841 aaacccacct tcctattcca gcctttttaa ctacgggacc ccaactcctg agaaccaggg
      901 agcagcctct gagagagaac aggagctcat atacaccatt tctgggcagg gttcatcctc
      961 ggagagatca tacactggac atcttcctct ggacctgccc cctagatatg aagaaaaaga
     1021 aactgcccca gccacaccct tgggtgcccc ttctgatgca tccccgccat gagctatgga
     1081 ctcaagcaca gttttatata tatcatggat tactatttta tttaatttgt tttttttaat
     1141 aaaacataca taccaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
