LOCUS       NM_001418283            3034 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus transmembrane protein 169 (Tmem169), transcript
            variant 3, mRNA.
ACCESSION   NM_001418283 XM_006496053
VERSION     NM_001418283.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3034)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114905.10.
            
            On Mar 17, 2023 this sequence version replaced XM_006496053.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.127503.1,
                                           SRR17784648.488059.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                AC114905.10        62526-62603
            79-204              AC114905.10        71051-71176
            205-613             AC114905.10        75901-76309
            614-3034            AC114905.10        78815-81235
FEATURES             Location/Qualifiers
     source          1..3034
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 36.48 cM"
     gene            1..3034
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /note="transmembrane protein 169"
                     /db_xref="GeneID:271711"
                     /db_xref="MGI:MGI:2442781"
     exon            1..78
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            79..204
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            205..613
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             343..1236
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /codon_start=1
                     /product="transmembrane protein 169"
                     /protein_id="NP_001405212.1"
                     /db_xref="GeneID:271711"
                     /db_xref="MGI:MGI:2442781"
                     /translation="MEESAPVESQGQLPSPHHGSLRRAVAAVLALDGESTLGRRKKRR
                     KDSRPESIIIYRSDNEKTDEEPEESEGGDRPKEEEGEDFLDYPGDDGVWNMPLDSRYV
                     TLTGTITRGKKKGQMVDIHVTLTEKELQELTKPKELSREAAPEGRRACQVGADQGPHV
                     VLWTLVCLPVVFVLSFVVSFYYGTITWYNIFLVYNEERTFWHKISCCPCLILFYPVLI
                     MTMASSLGLYAAVAQLSWSWAAWWRAACDMEKGFCGWLCSKLGLEDCSPYSIVELLES
                     DNISGNLSNKDPIQEVETSTV"
     exon            614..3034
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3014..3019
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3034
                     /gene="Tmem169"
                     /gene_synonym="A830020B06Rik"
                     /note="major polyA site"
ORIGIN      
        1 agagctggac cgctcctggc ggccgcccgc agccgtctgc atcctcagct tccctcctgg
       61 gtcccagtga aggtgtggag acatcatgtg accacctgaa acctgcatta ttagaaagga
      121 gaaataggac aagttcacaa cggcctgtaa ttacagctct ggagggacga gacacctctg
      181 gcctttgcag gtacctgtgc tcaggtcgca ggcatcctca ggggcatgtc tgcatagccc
      241 tttcccgata gaaaaaaaac ctgtgtgatg tatggcgctt gagtttgcac aaacaagtca
      301 gactcctctg taaagtaagc tcagctagct ctcaggccta ggatggaaga gtcggcaccg
      361 gtggaaagtc agggtcagct cccaagcccc caccacggct cactgaggag ggcagtggct
      421 gctgtcctgg ccctggatgg ggaatccaca ttgggccgca ggaagaagag gaggaaagac
      481 tcccgcccgg aatccatcat catctaccgg tcagataatg agaagacgga tgaggagcct
      541 gaagaatctg aaggtggaga tcggcctaaa gaggaagagg gggaggactt cctggactat
      601 cctggggatg atggtgtgtg gaacatgcct ctggacagcc gctatgtcac actaaccggg
      661 accatcacac gagggaagaa gaagggtcag atggtggata tccatgtcac tctgacagag
      721 aaggagctgc aggagctgac caaacccaag gagctgtcca gggaagcagc ccccgaggga
      781 aggagggcct gccaggtcgg ggcggaccag gggccacacg tggtcctctg gacactggtc
      841 tgcctgcctg tggtctttgt gctctctttc gttgtgtctt tctattatgg caccatcacc
      901 tggtacaaca tctttctggt gtacaatgaa gagaggacct tctggcataa gatctcctgc
      961 tgtccgtgcc tcattctctt ctacccagtg ctcatcatga ccatggcctc ttccctgggg
     1021 ctctatgccg ccgtggctca gctctcatgg tcctgggcag cgtggtggcg agctgcctgt
     1081 gacatggaga aaggcttctg tggttggctc tgcagcaagc tgggtctgga ggactgttct
     1141 ccctacagca ttgtggaact gctggagtct gataatatct cgggcaatct ctccaacaag
     1201 gaccccatcc aggaggtaga aacctctact gtctagacct ctagtgactt ccttcctagg
     1261 tcctagttgt ctatagtcat tcaatggaat ctagtagttc tttccttaaa ctatctaatg
     1321 ccctctacat tcctgggaca gcctagccca cactggcgta actcatcatc ttcattattc
     1381 caagatgacg gaaaatagaa aagcgacttg tgccaaagcc gtgcatctga aatacaaatg
     1441 cgtcttgact ctttgcccta taatgactgt ttatgtgcta catgaagata catcataaat
     1501 tccttcaggg gcctgaagat gttattggtg cctatgaccc aggggagtgt gtgcctaaat
     1561 gtgacagaaa ggataaagag gctcaggggt gaccagatcc gccaagataa tagatgggga
     1621 tggagtgaca catttaggga gttaggctat taaagactgt gcatcactgt atttagatag
     1681 aactgcacat aactaaagcc acaaatatta gtgagccaaa caagagagaa atatacttcc
     1741 tttttatgca gatgtcagga ggcagatcat cccaagacct atgaagtttt ctggggttca
     1801 ctggatggca gaatgtggcc cttggtgctc ctcagttttt aaatattgac tacaactctt
     1861 aactgtcata gcaacagaga tggaaaggag agcacactca gcctatttaa ggaggcttta
     1921 aaagcctccc ccctcaatat ttattatctc tcattggcca tactatagtc acatgacccc
     1981 acaatcaaag gatgctggga aatgtagtct ttcatctggg caattatatt cttagatgaa
     2041 tactggggtt atgtgaattt gagaaaaggg ggatagtggc tattgggtag tcaagtacaa
     2101 atcgatatct tagaacaggt atttagatac atccagaatt ccaaattaca aatgcagctt
     2161 tatttgttta tttatataat tattttggcc ctagtcttag atggagagtt tatacataga
     2221 tctgagttac atatactatg catatgcctt agacagtagc atctcgtgta cttggcaact
     2281 taaccttttg tcaagtggtt tcagggttct ttggaaagac ccattagata ggagcatatg
     2341 gtcacacagc cacagcacaa ttcttcctgg aaaggaaggg gaacagggat taacagtatt
     2401 taatctataa agatggagaa gagagagaga ttgagagaga gagagtaaat cttccaaacg
     2461 ctaacccagc agggatcagt agctcaaaat tcaaaccaca gtttgcctgt ggtttcacca
     2521 aacctaggag ccttattcat ttgctcagac ctttctagca tgaagcttct ctgacagggt
     2581 taggagtgat gtaacagatt aatccagatg aaaagattct ggactggaga aataacagct
     2641 tcatttttaa gagtgtcctg atttcaaaat gctgagtccc aagaggtcag tgggtttggg
     2701 gtttgggttc ataaaaggag cgatattatt attattatta tcattattat tatcattatt
     2761 attatttttg atgtgtgtgt ctcagaaaga agtgctctga agcactcaac aaaccagagg
     2821 ggttgatcaa gctcccccaa aaccagccag ggacatttat ttaatgtatg gtgctgaact
     2881 ccactttcag agaattaaaa aaaaaatcct gttattagtt tgatcaaaag gaaaagaaaa
     2941 tgtgtccagt atttttgagg atagctgtgg tgcttcctgg tgcatttcca gagatatgaa
     3001 taatataaat gaaaataaag ataataaact ctga
//
