LOCUS       NM_026938                652 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus transmembrane protein 160 (Tmem160), transcript
            variant 1, mRNA.
ACCESSION   NM_026938 XM_485868
VERSION     NM_026938.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Dai,X., Wu,Z., Ruan,R., Chen,J., Huang,C., Lei,W., Yao,Y., Li,L.,
            Tang,X., Xiong,J., Feng,M. and Deng,J.
  TITLE     TMEM160 promotes tumor immune evasion and radiotherapy resistance
            via PD-L1 binding in colorectal cancer
  JOURNAL   Cell Commun Signal 22 (1), 168 (2024)
   PUBMED   38454413
  REMARK    GeneRIF: TMEM160 promotes tumor immune evasion and radiotherapy
            resistance via PD-L1 binding in colorectal cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 652)
  AUTHORS   Segelcke,D., Fischer,H.K., Hutte,M., Dennerlein,S., Benseler,F.,
            Brose,N., Pogatzki-Zahn,E.M. and Schmidt,M.
  TITLE     Tmem160 contributes to the establishment of discrete nerve
            injury-induced pain behaviors in male mice
  JOURNAL   Cell Rep 37 (12), 110152 (2021)
   PUBMED   34936870
REFERENCE   4  (bases 1 to 652)
  AUTHORS   Dai,N., Zhao,L., Wrighting,D., Kramer,D., Majithia,A., Wang,Y.,
            Cracan,V., Borges-Rivera,D., Mootha,V.K., Nahrendorf,M.,
            Thorburn,D.R., Minichiello,L., Altshuler,D. and Avruch,J.
  TITLE     IGF2BP2/IMP2-Deficient mice resist obesity through enhanced
            translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial
            proteins
  JOURNAL   Cell Metab 21 (4), 609-621 (2015)
   PUBMED   25863250
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164880.3.
            
            On Mar 24, 2023 this sequence version replaced NM_026938.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC028534.1, BG970544.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AC164880.3         56577-56805         c
            230-322             AC164880.3         55534-55626         c
            323-652             AC164880.3         54257-54586         c
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.13 cM"
     gene            1..652
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /note="transmembrane protein 160"
                     /db_xref="GeneID:69094"
                     /db_xref="MGI:MGI:1916344"
     exon            1..229
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..588
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /product="transmembrane protein 160 isoform 1 precursor"
                     /protein_id="NP_081214.1"
                     /db_xref="CCDS:CCDS20849.1"
                     /db_xref="GeneID:69094"
                     /db_xref="MGI:MGI:1916344"
                     /translation="MGGGWWWARVARLARLRFRGSLQPPQRPRSGGARGSFAPGHGPR
                     AGASPPPVSELDRADAWLLRKAHETAFLSWFRNGLLSSGIGVISFMQSDMGREAAYGF
                     FLLGGLCVVWGGASYAVGLAALRGPMQLSLAGAAAGVGAVLAASLLWACAVGLYMGQL
                     ELDVELVPEDDGAASTEGPDEAGRPPPE"
     exon            230..322
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            323..652
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      631..636
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      652
                     /gene="Tmem160"
                     /gene_synonym="1810008O21Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtcgcggccc cattgcgagc catgggaggc ggctggtggt gggctcgggt cgcgcgcctg
       61 gcccgcctgc gcttccgggg gtctctgcag cctcctcagc ggccccgcag cgggggcgcg
      121 cgcgggtcct tcgccccggg ccacgggcca cgcgcgggag cgtcgccgcc tccagtgtcc
      181 gagctggatc gcgcggacgc ttggctcctc cgcaaggcac atgagacagc ttttctctcc
      241 tggttccgaa atggacttct gtcatccggc attggggtca tctccttcat gcagagtgac
      301 atgggccggg aagctgccta tggcttcttc ctgctgggtg gcctgtgcgt ggtgtggggc
      361 ggagcctcct atgcggtggg tctggcagcg ctgcggggac ccatgcaact gtcgcttgct
      421 ggtgctgccg ctggtgtggg ggcagtgttg gctgccagtc tgctctgggc ttgtgcagta
      481 ggtctctaca tgggccagtt ggaactggac gtggaactgg tgcctgagga tgatggggca
      541 gccagtacag aaggcccaga tgaagcgggc aggccacccc ctgagtaaac aacagggctg
      601 tggggactgg ctgggcctga cgactgggac attaaaacct gacccttccg ca
//
