LOCUS       NM_001002267            1744 bp    mRNA    linear   ROD 04-OCT-2024
DEFINITION  Mus musculus transmembrane protein 158 (Tmem158), mRNA.
ACCESSION   NM_001002267 XM_486272
VERSION     NM_001002267.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1744)
  AUTHORS   Ulmke,P.A., Sakib,M.S., Ditte,P., Sokpor,G., Kerimoglu,C., Pham,L.,
            Xie,Y., Mao,X., Rosenbusch,J., Teichmann,U., Nguyen,H.P.,
            Fischer,A., Eichele,G., Staiger,J.F. and Tuoc,T.
  TITLE     Molecular Profiling Reveals Involvement of ESCO2 in Intermediate
            Progenitor Cell Maintenance in the Developing Mouse Cortex
  JOURNAL   Stem Cell Reports 16 (4), 968-984 (2021)
   PUBMED   33798452
REFERENCE   2  (bases 1 to 1744)
  AUTHORS   Nieto,M., Barradas,M., Criado,L.M., Flores,J.M., Serrano,M. and
            Llano,E.
  TITLE     Normal cellular senescence and cancer susceptibility in mice
            genetically deficient in Ras-induced senescence-1 (Ris1)
  JOURNAL   Oncogene 26 (12), 1673-1680 (2007)
   PUBMED   16964279
  REMARK    GeneRIF: Ris1-deficient embryonic fibroblasts were
            indistinguishable from wild-type cells regarding their
            proliferation properties, immortalization, senescence and oncogenic
            transformation
REFERENCE   3  (bases 1 to 1744)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            W89232.1, AK009669.1, AC134248.3, AI849320.1 and BE631438.1.
            
            On Oct 27, 2006 this sequence version replaced NM_001002267.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                W89232.1           1-25
            26-427              AK009669.1         2-403
            428-428             AC134248.3         201181-201181       c
            429-1017            AK009669.1         405-993
            1018-1459           AI849320.1         23-464
            1460-1732           AK009669.1         1435-1707
            1733-1744           BE631438.1         1-12                c
FEATURES             Location/Qualifiers
     source          1..1744
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 73.92 cM"
     gene            1..1744
                     /gene="Tmem158"
                     /gene_synonym="2310037P21Rik; Ris1"
                     /note="transmembrane protein 158"
                     /db_xref="GeneID:72309"
                     /db_xref="MGI:MGI:1919559"
     exon            1..1733
                     /gene="Tmem158"
                     /gene_synonym="2310037P21Rik; Ris1"
                     /inference="alignment:Splign:2.1.0"
     CDS             245..1105
                     /gene="Tmem158"
                     /gene_synonym="2310037P21Rik; Ris1"
                     /note="BINP binding protein p40BBP; brain injury-derived
                     neurotrophic peptide (BINP) binding protein; Ras-induced
                     senescence 1; 40 kDa BINP-binding protein; ras-induced
                     senescence protein 1"
                     /codon_start=1
                     /product="transmembrane protein 158 precursor"
                     /protein_id="NP_001002267.2"
                     /db_xref="CCDS:CCDS23658.1"
                     /db_xref="GeneID:72309"
                     /db_xref="MGI:MGI:1919559"
                     /translation="MLPLLAALLAAACQLPPAHGGATDAPGLAGTPPNASANASFTNE
                     HSTPRLLASAASAPPERAGPEEAPAAPCNISVQRQMLSSLLVRWGRPRGLQCDLLLFS
                     TNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRLRAPAGAPTA
                     LPAYPAAEPGPLWLQGEPRHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIV
                     VWSVAALIWPVPIIAGFLPNGMEQRRTTAGAPAAAPAAVPAGTTAAAAAAAAAAAAAA
                     AAVTSGVAPK"
     regulatory      1714..1719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem158"
                     /gene_synonym="2310037P21Rik; Ris1"
                     /note="hexamer: AATACA"
     polyA_site      1733
                     /gene="Tmem158"
                     /gene_synonym="2310037P21Rik; Ris1"
                     /note="major polyA site"
ORIGIN      
        1 ctctctcgtt tcgccgcgag ccagcagagc ctcctggccg tccaagggcc ccagctctgg
       61 gggcagcgga acctcgacga gcggagtctg aagaggccat cgcggcccgt gagccggtgt
      121 cgtcccaata cactggcaga gttccgcctc ggccttccag gccccgcggt tccctcaccg
      181 gacggtcgcc tgcgcgccat gcagccgccg cctgccccgc gcgcgtaggc gctcgccaca
      241 ggccatgctg ccccttctcg ccgcgctact ggccgccgcc tgccagctgc cgccggcgca
      301 cggcggggcc acggatgcgc ccggccttgc agggacgccc ccaaacgcct cggccaatgc
      361 gtccttcacc aacgaacact ccaccccgcg tctgctggca tcggcggcat cggcgccccc
      421 agagcgcgcg ggcccagagg aggctccggc ggcgccctgc aacatcagcg tgcaacgaca
      481 gatgctgagc tcgctgctcg tgcgctgggg ccgcccgcgg ggcttgcagt gcgacctgct
      541 gctcttctct accaacgcgc acggccgcgc cttcttcgcc gccgccttcc accgcgtcgg
      601 gccaccactg ctcatcgagc atctggggct ggcggcgggc ggcgcgcagc aagacctgcg
      661 cctgtgcgtg ggctgcggct gggtgcgcgg ccgcctgcgg gctcccgccg gggctcccac
      721 cgcgctgcct gcctacccgg cggccgagcc ggggccgctg tggctgcagg gcgagcctcg
      781 tcacttctgc tgcctggact tcagcctgga ggagctgcag ggcgagccgg gctggcggct
      841 gaaccgcaag cccatcgagt ctacgctggt ggcctgcttc atgaccctgg tcatcgtggt
      901 gtggagcgtg gccgccctca tctggccggt gcccatcatt gccggcttcc tgcccaacgg
      961 catggagcag cgccggacca ccgccggcgc ccccgcggcc gctcctgcag ccgtacccgc
     1021 ggggactacc gccgctgccg ccgccgctgc tgcagctgct gctgctgctg ccgcggctgt
     1081 cacctcgggg gtggctccta agtgaccccc tccgccccgc gtccgcgctg tgtaagcgct
     1141 cgcacgcgcc ttcctcaccg gagacggggc aggtgcgctt cgtgctgtcc ttattgttca
     1201 tccttttccc gggaggggac cgcagagagg cacaaatgag gtgggaaagt ggggtttgtg
     1261 ctgaggttct ggttcggaag agcaggggca agctctcggg ctgaagggtg ggatccacgc
     1321 gtggctcgag gacacaaggg aaaccggctc tttcccctgc ggcaccccct ccctgcgccc
     1381 acatgccctt tatttatggc agaaagtgac cagatcctgt gtatttgttt tatatattta
     1441 ataactgttt taaatgaaag ttttagtaaa aaaaaataca aaacaaaaag attcaactgc
     1501 taaagctgtg gtaacaggag ctctttgtat ctgaatgtag ttgtatttga agcttcttgt
     1561 ttgttttttt aaaggggggg acgagggaag atttgacacg gatttattgt aattgcttac
     1621 aaaagaactt tatgaatctt ttccaagtcg atctattcag tgacatggcc tggtgggcgt
     1681 ttcttcttgt attaatgtgg ttttctggct tttaatacag acattttcct ccaaaaaaaa
     1741 aaaa
//
