LOCUS       NM_001142792            1025 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 150B (Tmem150b), transcript
            variant 1, mRNA.
ACCESSION   NM_001142792
VERSION     NM_001142792.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1025)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1025)
  AUTHORS   Liu,R., Ke,H., Shao,T., Qin,Y. and Zhao,S.
  TITLE     TMEM150B is dispensable for oocyte maturation and female fertility
            in mouse
  JOURNAL   Sci Rep 10 (1), 21381 (2020)
   PUBMED   33288838
  REMARK    GeneRIF: TMEM150B is dispensable for oocyte maturation and female
            fertility in mouse.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161197.9.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022651.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               AC161197.9         42768-42942
            176-235             AC161197.9         43326-43385
            236-303             AC161197.9         43474-43541
            304-431             AC161197.9         43939-44066
            432-615             AC161197.9         46998-47181
            616-1025            AC161197.9         51439-51848
FEATURES             Location/Qualifiers
     source          1..1025
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.72 cM"
     gene            1..1025
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /note="transmembrane protein 150B"
                     /db_xref="GeneID:330460"
                     /db_xref="MGI:MGI:2679718"
     exon            1..175
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..824
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transmembrane protein 224; modulator of macroautophagy
                     TMEM150B"
                     /codon_start=1
                     /product="modulator of macroautophagy TMEM150B isoform 1"
                     /protein_id="NP_001136264.1"
                     /db_xref="CCDS:CCDS51975.1"
                     /db_xref="GeneID:330460"
                     /db_xref="MGI:MGI:2679718"
                     /translation="MWNYLSLLPVILFLWAIAGIWIVFAIAVVNGSVDLNEGFPFISI
                     CGSYAPQSCIFGQVLNIGAALTVWICIVRHHQLRDWGVKTWQNQLILWSGILCALGTS
                     IVGNFQDKNQKPTHLAGAFLAFILGNLYFWLQFFLSWWVKGLPQPGPHWIKSLRLSLC
                     SLSTILIVAMIVLHALHMRSASAICEWVVAMLLFMLFGFFAVDFSILRGCTLHLHPRL
                     DSSLPQAPSGSPNIQMAQVL"
     exon            176..235
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /inference="alignment:Splign:2.1.0"
     exon            236..303
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /inference="alignment:Splign:2.1.0"
     exon            304..431
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /inference="alignment:Splign:2.1.0"
     exon            432..615
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /inference="alignment:Splign:2.1.0"
     exon            616..1025
                     /gene="Tmem150b"
                     /gene_synonym="A630041N19; Tmem224"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcttccagc cagtgggacc acaaaagcag gtgggccgtc ttcagcacca cacacctaaa
       61 gactgcttgg agatccagct tcttcacttc cactgcagag cgcagcaatg tggaattacc
      121 tgtccttgct gcctgtcatc ttatttctgt gggctatagc tggcatctgg attgtttttg
      181 caatcgctgt ggttaatggt tctgtggacc tcaacgaagg cttccctttt atcagtatct
      241 gtggctctta tgctcctcag agctgcattt tcggccaagt cctcaatata ggagctgctc
      301 taactgtttg gatctgcatt gtgcgtcatc accaactccg ggactggggc gtcaaaacct
      361 ggcaaaacca gctaattctg tggtcgggga tcctttgtgc cctgggtacc tccatagtag
      421 gcaacttcca ggacaagaac cagaagccca cacacttggc aggggccttt ctggccttca
      481 tcctgggcaa cctgtacttc tggctacagt tttttctgtc ctggtgggtg aaaggcctgc
      541 cccaacctgg gccccactgg attaagtctc tacgcctgag cctctgcagc ctctccacca
      601 tcctcatcgt ggctatgatt gtcctgcacg ccctacatat gcgctctgcc tcggctatct
      661 gcgagtgggt agtggccatg ttgctcttta tgctatttgg cttctttgcc gtggacttct
      721 ccattttgcg tggctgcacc ctgcacttac atccccgtct ggactccagc ctcccacaag
      781 ctccctctgg gtctccaaat atacagatgg cacaggtgct ctgaccagac cccttgctac
      841 tgatagagga agaaagatgg ggctaaccca ggctcactca acaacaccct ggaggctgat
      901 gtggacattc tggagaatgc acggcaaagt ggacttgtgc tcactgctta gacaggcagt
      961 atcttggtac ccacctgtcc ctgtgatcag aagcacccca ggaattgaga ggcaaaggcc
     1021 agcca
//
