LOCUS       NM_001403202            2802 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus transmembrane protein 145 (Tmem145), transcript
            variant 1, mRNA.
ACCESSION   NM_001403202
VERSION     NM_001403202.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2802)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2802)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2802)
  AUTHORS   Potter,P.K., Bowl,M.R., Jeyarajan,P., Wisby,L., Blease,A.,
            Goldsworthy,M.E., Simon,M.M., Greenaway,S., Michel,V., Barnard,A.,
            Aguilar,C., Agnew,T., Banks,G., Blake,A., Chessum,L., Dorning,J.,
            Falcone,S., Goosey,L., Harris,S., Haynes,A., Heise,I., Hillier,R.,
            Hough,T., Hoslin,A., Hutchison,M., King,R., Kumar,S., Lad,H.V.,
            Law,G., MacLaren,R.E., Morse,S., Nicol,T., Parker,A., Pickford,K.,
            Sethi,S., Starbuck,B., Stelma,F., Cheeseman,M., Cross,S.H.,
            Foster,R.G., Jackson,I.J., Peirson,S.N., Thakker,R.V., Vincent,T.,
            Scudamore,C., Wells,S., El-Amraoui,A., Petit,C.,
            Acevedo-Arozena,A., Nolan,P.M., Cox,R., Mallon,A.M. and Brown,S.D.
  TITLE     Novel gene function revealed by mouse mutagenesis screens for
            models of age-related disease
  JOURNAL   Nat Commun 7, 12444 (2016)
   PUBMED   27534441
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2802)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156992.13.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.479063.1,
                                           SRR17784647.1225994.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849379, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               AC156992.13        71676-71863         c
            189-263             AC156992.13        70796-70870         c
            264-341             AC156992.13        70604-70681         c
            342-428             AC156992.13        70425-70511         c
            429-530             AC156992.13        70241-70342         c
            531-615             AC156992.13        70054-70138         c
            616-687             AC156992.13        69885-69956         c
            688-756             AC156992.13        69702-69770         c
            757-837             AC156992.13        69300-69380         c
            838-916             AC156992.13        69118-69196         c
            917-1010            AC156992.13        68887-68980         c
            1011-1183           AC156992.13        68180-68352         c
            1184-1304           AC156992.13        66479-66599         c
            1305-2802           AC156992.13        61763-63260         c
FEATURES             Location/Qualifiers
     source          1..2802
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.74 cM"
     gene            1..2802
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /note="transmembrane protein 145"
                     /db_xref="GeneID:330485"
                     /db_xref="MGI:MGI:3607779"
     exon            1..188
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1883
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /product="transmembrane protein 145 isoform 1 precursor"
                     /protein_id="NP_001390131.1"
                     /db_xref="GeneID:330485"
                     /db_xref="MGI:MGI:3607779"
                     /translation="MEPSRAPVLRRLLPPLLLLLLPLYPRTRAKYVRGNLSSKEDWVF
                     LTRFCFLSDYGRLDFRFRYPEAKCCQNILLYFDDPSQWPAVYKARDKDCLAKESVIRP
                     ENNQVINLTTQYAWSGCQVVSEEGTRYLSCSSGRSFRSVRERWWYIALSKCGGDGLQL
                     EYEMVLTNGKSFWTRHFSADEFGILETDVTFLLIFTLIFVLSCYFGYLLKGRQLLHTT
                     YKMFMAAAGVEVLSLLFFCIYWGQYATDGIGNGSVKILAKLLFSSSFLIFLLTLILLG
                     KGFTVTRGRISHSGSVKLSVYMTLYTLTHVVLLIYEAEFFDPGQVLYTYESPAGYGLI
                     GLQVAAYVWFCYAVLVSLRHYPEKQPFYVPFFAAYTLWFFAVPVMALIANFGIPKWAR
                     EKIVNGIQLGIHLYAHGVFLIMTRPSAANKNFPYHVRTSQIASAGVPGPGGSQSADKA
                     FPQHVYGNVTFISDSVPNFTELFSIPPPTSSVSSAAPAPEELLAPPLEYLTPLPAPPP
                     PPAHWRLSPPLAFRTPHAPTPRLDRPPAPAPTLPDWVLALLRTPPRTPRAVPPPPAFR
                     GWSPSPPPPPEFARRTPTPPLEYLAPLPRRPATHSFPD"
     exon            189..263
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            264..341
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            342..428
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            429..530
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            531..615
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            616..687
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            688..756
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            757..837
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            838..916
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1010
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1183
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1304
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..2802
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2772..2777
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2802
                     /gene="Tmem145"
                     /gene_synonym="B930076A02Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcgcgctctc gcctccgtca ccgggccgga gcgggagccg gagccgagcc gaggccagag
       61 cgggaggaat ggagccctcc cgcgcgcccg tgctgcgccg cctgctgccg ccgctactgc
      121 tcttgctgct gccactgtac ccccgcaccc gggccaagta cgtgcggggc aacctcagct
      181 ccaaagagga ttgggtgttc ctgacaagat tttgtttcct ttcggattat ggacgactgg
      241 acttccgatt ccgatacccc gaggctaagt gctgtcagaa catcctcctc tactttgacg
      301 acccatccca gtggccagcg gtgtacaagg caagggacaa ggactgtttg gccaaggagt
      361 cggtgatcag gccagagaac aaccaggtca tcaatctcac cactcagtac gcctggtcgg
      421 gctgtcaggt ggtgtcagag gagggaactc gctacctgag ctgctccagt ggccgcagct
      481 tccgttctgt gcgtgaaaga tggtggtata tcgcactcag caagtgtggg ggagacgggc
      541 tgcagttgga gtatgagatg gtccttacca acggcaagtc tttctggaca cggcacttct
      601 cagctgatga atttgggatt ttggagacag atgtgacctt tctcctcatc ttcaccctta
      661 tctttgtcct ctcttgttac tttggatatt tgctgaaagg ccgtcagtta ctccacacaa
      721 cttataaaat gttcatggct gcagcaggag tggaggtcct gagcctcctg tttttctgca
      781 tctactgggg ccagtatgcc acagatggca ttggcaatgg cagcgtgaag atcttggcca
      841 agctgctctt ctcctccagt ttcctcatct tcctgctcac actcatcctc ctcgggaagg
      901 gattcacggt gacacgaggc cgcatcagcc actcaggctc cgtgaagttg tctgtgtaca
      961 tgaccctgta caccctcacc cacgtggtgt tgctcatcta cgaggcagaa ttctttgacc
     1021 caggccaggt actatacaca tacgagtctc cggctggtta tgggctcatc gggctgcagg
     1081 tggctgccta tgtgtggttc tgctatgctg tgctggtctc ccttcggcac tatccagaga
     1141 agcagccctt ttatgtgccc ttctttgctg cctatactct ctggttcttc gctgtccccg
     1201 tcatggctct gatcgccaat tttgggatcc caaagtgggc ccgagagaag atagtcaacg
     1261 gtatccagct ggggatccac ctctatgccc atggcgtgtt tctgatcatg acccgcccat
     1321 cggcggccaa caagaacttt ccgtaccacg tgcgaacttc acagatcgcc tccgctgggg
     1381 tccctggacc tggagggagc caatcagcag ataaagcctt cccgcagcac gtctatggaa
     1441 acgtgacgtt catcagcgac tcggtgccca acttcacgga gctcttctcc atccccccgc
     1501 caacctcctc tgtaagctcc gcagccccgg cgcccgagga gctgctggcg ccgcccctgg
     1561 agtacctgac cccgctcccc gccccgccgc caccccctgc tcattggcgt ctgagcccac
     1621 ccctggcctt ccgtactccc catgccccga cgccccgcct cgaccgtccc ccggcgcccg
     1681 cgcccaccct gccagactgg gtcctggcgc tgttgcgcac gcccccgagg acaccccgcg
     1741 ctgtgccccc gccgcctgcc ttccgaggct ggtccccatc tcccccaccg cctccagagt
     1801 ttgcccggcg caccccaact ccaccccttg aatacctggc cccactgccc aggcgcccag
     1861 ccacccactc cttccctgat tgacaagtgc gtccatattt ggggtggtgg gagtcctcta
     1921 gggggagggg gacgggcctt cggggccgct tttgctcccc cgagggttct gggcagcctc
     1981 tgaccctgac cccccatccc aggccgggaa gcaggtggag gagacagcgg tggcggcggc
     2041 ggtggccccg aggggccgtg tggtgaccat ggccgaaccc ggcgcagcct ccccgccccc
     2101 acccgctcgg ttctccaagg cggtcgactc gggctgggat ggcccgacgc cgtcctacca
     2161 gccgcttgtg ccccagacgg cggcgccgca caccggcttc accgaatact tcagcatgca
     2221 cacagccggg ggccctgcac ccccggtctg agcatccctt ccccgcctct gccccacggg
     2281 cggcgcaccg ggccccggct gggctccgga accccgtttc tctcccggcc caagggctcg
     2341 gccatgccag gcatcccgcg cccctcccac accccgcgcc cactttggat gcgctgcgtc
     2401 ccgccccttt ccctcttgtg ccaaacggtc ccgcgggagc cgttctccgc gtcccctccc
     2461 tcagcccctg ccccgaatgg ctccggaatc tggactcccg ctgttccgtg atctccgccc
     2521 ccctgacccc cttcgagacc tctgaccctg ctggactccg gaacacccgt gacgaccgcc
     2581 tggaccctgc ccgaccctcc aggaccctgc gaccctcgag ccactgttta gagacggata
     2641 ttgtgaagtt ggtctctact ttgaaaccct ccttggggtt tgtgacctcg gacctgtgct
     2701 ttgtccgtcc atctgaatgc caaggaccat cacatggtct gtggcagaaa gacgttttct
     2761 cttcttgcca aaataaagag gattcgttga gtttttaatc ta
//
