LOCUS       NM_001040130             808 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 141 (Tmem141), transcript
            variant 1, mRNA.
ACCESSION   NM_001040130 XM_619738 XM_897470 XM_914471 XM_923257 XM_979127
            XM_979169
VERSION     NM_001040130.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 808)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   2  (bases 1 to 808)
  AUTHORS   Bulfone,A., Menguzzato,E., Broccoli,V., Marchitiello,A.,
            Gattuso,C., Mariani,M., Consalez,G.G., Martinez,S., Ballabio,A. and
            Banfi,S.
  TITLE     Barhl1, a gene belonging to a new subfamily of mammalian homeobox
            genes, is expressed in migrating neurons of the CNS
  JOURNAL   Hum Mol Genet 9 (9), 1443-1452 (2000)
   PUBMED   10814725
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY704611.1, AK004380.1, BY648636.1, CD774285.1 and AI852650.1.
            
            On Oct 19, 2007 this sequence version replaced NM_001040130.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: DV065834.1, AK004380.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                BY704611.1         2-64
            64-69               AK004380.1         65-70
            70-375              BY704611.1         71-376
            376-621             AK004380.1         378-623
            622-755             BY648636.1         261-394
            756-789             CD774285.1         21-54               c
            790-808             AI852650.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..808
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 17.57 cM"
     gene            1..808
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /note="transmembrane protein 141"
                     /db_xref="GeneID:51875"
                     /db_xref="MGI:MGI:1098773"
     exon            1..69
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..342
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 141 isoform 1"
                     /protein_id="NP_001035219.2"
                     /db_xref="CCDS:CCDS50534.1"
                     /db_xref="GeneID:51875"
                     /db_xref="MGI:MGI:1098773"
                     /translation="MVNLGLSRVDDAVAARHPGLEEFAACQSHAFMKGVFTFVTGTGA
                     TFGLLMFIKRKFPYPVQWSFLVSAIAGSVASYRVTSMECQKCSNLWLFLETGQLPKDI
                     STDPHD"
     exon            70..136
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /inference="alignment:Splign:2.1.0"
     exon            137..220
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /inference="alignment:Splign:2.1.0"
     exon            221..328
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /inference="alignment:Splign:2.1.0"
     exon            329..793
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      733..738
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /note="hexamer: AATAAA"
     polyA_site      757
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /note="major polyA site"
     regulatory      774..779
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
                     /note="hexamer: ATTAAA"
     polyA_site      779
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
     polyA_site      792
                     /gene="Tmem141"
                     /gene_synonym="1110065P14Rik; D2Ertd217e"
ORIGIN      
        1 agaacctgac caaccatggt gaatctgggc ttgtcccgtg tggatgacgc cgtggccgcc
       61 aggcacccgg gactcgagga atttgctgcc tgccagtcgc acgccttcat gaagggcgtt
      121 ttcacttttg tcacaggcac tggtgcgact tttggcctgc tgatgttcat taagaggaag
      181 tttccatacc ctgtgcagtg gagcttccta gtgtctgcca ttgcaggatc tgtggccagc
      241 tacagagtga caagtatgga gtgtcagaaa tgcagcaatc tctggctctt cctggagacc
      301 gggcagctcc ccaaagacat aagcacagat cctcacgact agaagcgctc tggctgctga
      361 ggtgcaggat gcgaagcagg gaagatccta gagcacagat ctaacgtcat ctaactccag
      421 gacagtccct cctacctcag caaacacaca cacacacatg catcctctag tgtcatctct
      481 ctcctacaca tgcatgtggg gtcctgcctg aaaaacctgt gaagactact gctgcaccaa
      541 atccaggacc tgccagctcg gaacaaggct tgggaggggg agatcttccg cagagcagca
      601 aggagcctca gagaggcttg aatcctgttg cacccagctg ctggagcagc agcctgcatg
      661 tgttgagaga gacttgagtg ctttctctga tctctgcccc aaatccaagg agaatgttgg
      721 agagttgtag ctaataaatg gcttgtcctt tttcctatgt gagctctgaa gcaattaaac
      781 acgtgctagt gagaaaaaaa aaaaaaaa
//
