LOCUS       NM_197986               2614 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus transmembrane protein 140 (Tmem140), transcript
            variant 1, mRNA.
ACCESSION   NM_197986 XM_133069
VERSION     NM_197986.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2614)
  AUTHORS   Watahiki,A., Waki,K., Hayatsu,N., Shiraki,T., Kondo,S.,
            Nakamura,M., Sasaki,D., Arakawa,T., Kawai,J., Harbers,M.,
            Hayashizaki,Y. and Carninci,P.
  TITLE     Libraries enriched for alternatively spliced exons reveal splicing
            patterns in melanocytes and melanomas
  JOURNAL   Nat Methods 1 (3), 233-239 (2004)
   PUBMED   15782199
REFERENCE   2  (bases 1 to 2614)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153869.7.
            
            On Feb 8, 2019 this sequence version replaced NM_197986.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030532.1, SRR5189679.66323.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               AC153869.7         118022-118216
            196-2614            AC153869.7         127404-129822
FEATURES             Location/Qualifiers
     source          1..2614
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 15.18 cM"
     gene            1..2614
                     /gene="Tmem140"
                     /gene_synonym="1110007F12Rik"
                     /note="transmembrane protein 140"
                     /db_xref="GeneID:68487"
                     /db_xref="MGI:MGI:1915737"
     exon            1..195
                     /gene="Tmem140"
                     /gene_synonym="1110007F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            196..2614
                     /gene="Tmem140"
                     /gene_synonym="1110007F12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             219..776
                     /gene="Tmem140"
                     /gene_synonym="1110007F12Rik"
                     /codon_start=1
                     /product="transmembrane protein 140"
                     /protein_id="NP_932103.1"
                     /db_xref="CCDS:CCDS19996.1"
                     /db_xref="GeneID:68487"
                     /db_xref="MGI:MGI:1915737"
                     /translation="MAFSRLWRNNHLPFVGIMILLAAALCLMFYALLWKAGNLADLPS
                     LRIGFYNFCLWKEDMGSLACYNFPELDVLGIPQVGLALARLGVYGALVLTVFVPLPLL
                     LAQYNRDEGEWRLAVCFLAASSILLAGGLSLFLSFVWKWLRLSFLGPALPALCLAQLL
                     LIFLLVATVRFPPRDKEDKNQWENC"
     regulatory      1525..1530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem140"
                     /gene_synonym="1110007F12Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      1536
                     /gene="Tmem140"
                     /gene_synonym="1110007F12Rik"
                     /note="major polyA site"
ORIGIN      
        1 acttgaacgc gactgcctgc gagtgcaggc agagcccagg agctctgagc tgtctgcttg
       61 cagcttctct cctctgccct ggtttctgga gcctgacttt agaaagcagc ccaggagaag
      121 atcgactccc cagacagacg ctgatttcct gtgtcacctt ttgatgagtg ttcctgggct
      181 ccagcgttgg tttttgtctc cctgcaacag cagaagatat ggccttctcc aggctgtggc
      241 ggaacaacca cctgcccttc gtgggcatca tgatcctctt ggccgcggcc ctgtgcctga
      301 tgttctacgc tctcctctgg aaggctggca acctcgctga cctacctagc ctgagaatcg
      361 gcttctacaa cttctgtctg tggaaggagg acatgggctc cctagcatgt tacaactttc
      421 ccgagctgga cgtgctgggc attcctcagg ttggactagc cctggccagg ctcggtgtgt
      481 atggagccct ggtcctcaca gtgttcgtcc ctctgcctct cctccttgcc cagtacaaca
      541 gagatgaggg agagtggcgg ctggccgtgt gcttcctggc ggcatcctcc attctgttgg
      601 ccggaggact aagcctcttc ctctccttcg tgtggaagtg gctcaggctc tccttcctgg
      661 ggcctgcctt gccagctcta tgcctagccc agctgttact catcttcttg cttgtggcca
      721 cggttaggtt cccgccacgg gataaggagg acaagaacca gtgggagaac tgttagtccg
      781 gtcttacaaa ggcttattat gggattgcaa gggttcggtt ccaactgtgc tccaagaagg
      841 tgccagagga cctgtgctga gtagttcttc tcagtcaccc tgtgtcatag ctaatgttga
      901 tctccagcac agcagagggg accactcact gtgcagacgg gctgtggtgt caaggaaccc
      961 agaggcggct tggagggctg gggtacctgc agtttcttag ggtaccatgt agctcattag
     1021 cacagggatt cctatagtcc caggcaggtg ggagtctgtc agaggccaaa cttccaagct
     1081 atcttggcaa agtgtcaaac tagaactctg tgatggttat ggcaacaaat gggatgatta
     1141 ggggaaaaac aaaaaacaaa caaacaagca acctgcttta acaccgagtc ctgtcagcac
     1201 aaagagaagc ctcactggct ttttagggtc ccctgaaggg gtccctggac ctgacagcaa
     1261 acaggaatca gctgttaagc catcctcgtg acccagggat gcagacgcaa aatgtgtcaa
     1321 ctcctggaag gtgaacagga ttgaatagtc gtcacaaaca cacaccgtgt cccctcacct
     1381 tacccagaac tggaaaggca gaaggcatgg tctttattat gcatcgcggc atcagtatat
     1441 attttgttca gtgcctgtat atcagaaaac ctacgtggca atgagttctt cattctgtgc
     1501 tcatcaaaag ccaaagtgaa tataaagaaa cctggactct ggtgtgatct tttgtcctca
     1561 gcgacccgtg tcccactctc ccttacaggg gtcaaggtgg aggccccagg aggaagagag
     1621 gtgactggtg gtagacaggg cctgtgtggc tcaccagcct cacagtctag gagcaggagg
     1681 ctcctagact ggcagggaac tgtgggcagt tgccagcctg tttggttggg agggtggaag
     1741 cttactgctg gactgtgtcg tgagggagac tgttcatagg tctctttaag tcgagatctg
     1801 gctgcctgtc tagaataccc atgttctcgg cagctctatt ttcctttgca tctggcaagt
     1861 aggcccaaga cctcactttt actgtgaatg aaactcgggg ctgggattgc catccctcag
     1921 ggcccgaggg tggagcaggg aaagtctgta acaggatgcg tttctgcatc ctgctacaga
     1981 aaaagtccca cccaaactga caacctcctg ggactggaag ttgggagcaa agcctggttt
     2041 tcgtgggtgg caggggccag taggggtggg cagcacccac agctctcagc tgaagcagtg
     2101 aacaattcat actaactgaa aaatatttcc ctgacgtact tcaacgcgtc ttcctcctcc
     2161 ttctcctcct ccgggcttct gctacaggga gagtccgaag cttctggtcc ccggggaggg
     2221 ctgaggcctg gagcaagaga gctgatcctg ctgtcttctt cctcactgct gctcccgggg
     2281 gacgaggaac agggagggga gagctgcagc ttatcagtgg cctccagaga ccgctgttcc
     2341 cagggctttt cctgtttgcg gccctgcaga gcagaagaaa cagctgtctc ggcacaaagg
     2401 gctcctttct ccaaggcacg agtttgacag tgctatggat gtaccctgag ccaaccgaaa
     2461 agccagcacg gcacacgacc aagttgggac atgctcccat ccacctcatg ggcacccaag
     2521 ctttctccac cccacacctc aggatcagga cccactaggg acagatgcag ggatctacat
     2581 atgaggaaca gcagagtaga aggagaaagg atcg
//
