LOCUS       NM_175408               1148 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 139 (Tmem139), mRNA.
ACCESSION   NM_175408
VERSION     NM_175408.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1148)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1148)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY032793.1, BY081702.1, BC096053.1 and CF585299.1.
            
            On May 25, 2007 this sequence version replaced NM_175408.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY032793.1, BY081702.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                BY032793.1         2-40
            40-352              BY081702.1         19-331
            353-1141            BC096053.1         36-824
            1142-1148           CF585299.1         437-443
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 20.54 cM"
     gene            1..1148
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /note="transmembrane protein 139"
                     /db_xref="GeneID:109218"
                     /db_xref="MGI:MGI:1924444"
     exon            1..57
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            58..319
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..719
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /codon_start=1
                     /product="transmembrane protein 139"
                     /protein_id="NP_780617.2"
                     /db_xref="CCDS:CCDS51757.1"
                     /db_xref="GeneID:109218"
                     /db_xref="MGI:MGI:1924444"
                     /translation="MVPRQLLGKLKQPFLFLSSASLLLGLALLVIQSDVAPVAYFFLC
                     LAGFCFVACLLACVMERCSRSMPSSRQTENPEASGQAQDNGAFEVPTYEQAVEVMDSQ
                     PQSHLQELEQPPPYSSIIISPGVEGAQPSQPDSPSTGSLKRRVGSEGTMTARGNPGRI
                     LRLRGPRVVATAPDLQSMRVAPKLEPSTPPPAYEISFAHADDDSVFYEDKWILP"
     exon            320..1147
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1120..1125
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /note="hexamer: CATAAA"
     polyA_site      1147
                     /gene="Tmem139"
                     /gene_synonym="A930027H06Rik"
                     /note="major polyA site"
ORIGIN      
        1 gccttctgtt cccggtgttc caagtctgcc aaggttttcg gcgtcccggg gagacaggtg
       61 ccctgggagg ggccatggtg ccaagacagt tgttggggaa actgaagcag ccatttctct
      121 tcctgagcag tgcctccctc ctcctggggc tggctttact ggtcatacag tctgatgtcg
      181 cccctgttgc ttacttcttc ctctgcttgg ctggcttttg ctttgttgct tgcctcctgg
      241 cctgtgttat ggaacgatgc tcccgatcga tgccaagctc caggcagact gagaatccag
      301 aggcctcagg ccaagcgcaa gacaatggag cttttgaggt gccaacctat gaacaggctg
      361 tagaggtgat ggattcacaa ccacagagcc acctccaaga gctggagcaa ccaccccctt
      421 acagcagtat cataatatcc ccaggagttg agggggcaca gcctagccaa ccagacagtc
      481 ccagcacagg cagtctgaaa aggcgagtgg gctcagaggg gacaatgact gccagaggaa
      541 accctggaag aattcttcga cttaggggtc cacgagttgt ggccactgct cctgatctgc
      601 aaagcatgag agtggccccc aaactggagc ctagtactcc acctcctgcc tatgaaatca
      661 gttttgctca tgctgatgat gacagtgttt tctatgaaga taaatggata cttccctaag
      721 tggtgccctc agaacctgtg cactcatttg cccagcattt cctagtgtct attggatcag
      781 aaactggttt tacccggaca tcacaatcga ggccttcaaa gcagcgggga gtcgggctgt
      841 ggcatgtcgt tcacagataa atggcacacc tagattcttc tggaaacatt ctggaaccta
      901 tctgatgacc agtatttcca gagtaaggtg gaagatgaga aagagataag ttaccaagag
      961 aagctggagg gatacctctg agtgactgct gtgtttcttc tattgtagac accaagtctc
     1021 cctgagattc ctgatggggt attacctacc aagataatga gagcttctaa ggttgagggg
     1081 agctgaatag tttgcacaag aacgggatgc tagtaaaaac ataaaaataa ctcgaatcaa
     1141 attccaaa
//
