LOCUS       NM_028411               1614 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 138 (Tmem138), transcript
            variant 1, mRNA.
ACCESSION   NM_028411
VERSION     NM_028411.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1614)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125093.4, AA030680.1, AK050471.1 and AK031921.1.
            
            On Oct 8, 2014 this sequence version replaced NM_028411.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058237.1, AK050471.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC125093.4         34434-34436
            4-286               AA030680.1         1-283
            287-1594            AK050471.1         2-1309
            1595-1612           AK031921.1         1243-1260
            1613-1614           AC125093.4         41341-41342
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 6.6 cM"
     gene            1..1614
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /note="transmembrane protein 138"
                     /db_xref="GeneID:72982"
                     /db_xref="MGI:MGI:1920232"
     exon            1..303
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            304..575
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             448..936
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 138 isoform 1"
                     /protein_id="NP_082687.1"
                     /db_xref="CCDS:CCDS29581.1"
                     /db_xref="GeneID:72982"
                     /db_xref="MGI:MGI:1920232"
                     /translation="MLQTGNYSLVLSLQFLLLSYDLFVNSFSELLRMAPVIQLVLFII
                     QDIAILFNIIIIFLMFFNTFVFQAGLVNLLFHKFKGTIILTSVYLALSISLHVWVMNV
                     RWKNSSSFSWTNGLQTLFVFQRLAAVLYCYFYKRTAVRLGDPRFYQDSLWLRKEFMQV
                     RR"
     exon            576..747
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            748..823
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1614
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1595..1600
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1614
                     /gene="Tmem138"
                     /gene_synonym="1700113I01Rik; 2900055D14Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggaaatgggg tttgcaagct aaggggcgcg ttcctgagcg gtccgattcc taggagcgct
       61 gcgtcctatc agccttgtct ctaaccacag accccgtcca gagacaggtg aaatgctggg
      121 gttaacaacc tcacgctagg gtcggccctc agcgaggcaa gatagaagaa ccggtcacag
      181 ggagagcctg agaaagcaaa gaccctaaca tggcgggcaa ttagcaatct acttccggaa
      241 tttaaagcca gcttccggaa gccgagcgag tgttcccatg acaaccgacg tcggttcctt
      301 gaggtccttg cattagagcc aaggaaacag ctccgatttg gaaaaactaa acatctctcc
      361 tggagttctg ggcagagaga aaaccagtag tcattttctt cggaactgtg gaatgtaccc
      421 ttgggagtcc cacaaatcag gcagaagatg ctccagaccg gtaactacag cctggtgctc
      481 tccctgcagt tcctgttgct gtcctatgac ctgttcgtca actccttctc agagctactc
      541 cgaatggctc ctgttatcca gcttgtgctg ttcatcatcc aggatattgc aatcctcttc
      601 aacatcatca taattttcct catgttcttc aacaccttcg tcttccaggc tggcctggtc
      661 aacctccttt tccataagtt caaagggacc atcattctga catctgtgta ccttgccctc
      721 agcatctccc tacatgtctg ggtcatgaac gtgcgatgga aaaactccag cagcttcagc
      781 tggacaaacg gcctgcaaac actgtttgta ttccagagac tagccgcagt gctctactgc
      841 tatttctaca aaaggacggc cgtgagactg ggtgaccccc gcttttacca ggactcactg
      901 tggcttcgca aggagttcat gcaagtccga aggtgaccac ttcatgtcac atgggtgaat
      961 acctttcctt cctggtagaa ggcgcctgcc tgggctgctc tccagggagg agcagccatt
     1021 ggcaccagga agcaggggga cttcctagga cacatttatg ctatctgtgc tcagcattca
     1081 agaaggaaga ttcaccaggc atggttggaa acagaggcag gaggattgct gtggtttgag
     1141 gccaccctag gcctacctaa tgagttctag gttagcctgt agagagagac cctatctccc
     1201 cccccccccc caaaaaaaag aacaaaaaaa aggaagacct tccttattgc aaattacagt
     1261 gtttccctgc cgcagactgt agtgcaaagt gcagtcttgc ctcctcaacc gcccacttcc
     1321 ttctcttcct actttgtacc actcactcac tgtctttccc tcctccttcc aaggatctgc
     1381 agctctggag ctaccactct aaagcttatg gttcagcctt ttaggtagca gcgagtcagc
     1441 ctaggccctg ttctgctgac cccatccttg agtgactgga ggatgcagag agtgacggcc
     1501 atgtcctcct gactgaccac accttagtcg tttagatttt atatccaaag tactttttta
     1561 cagttctaaa aggagataaa ttgaattttt ttttaataaa tggtagagtc tgtc
//
