LOCUS       NM_001078649            1517 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 134 (Tmem134), transcript
            variant 1, mRNA.
ACCESSION   NM_001078649
VERSION     NM_001078649.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Kalsotra,A., Xiao,X., Ward,A.J., Castle,J.C., Johnson,J.M.,
            Burge,C.B. and Cooper,T.A.
  TITLE     A postnatal switch of CELF and MBNL proteins reprograms alternative
            splicing in the developing heart
  JOURNAL   Proc Natl Acad Sci U S A 105 (51), 20333-20338 (2008)
   PUBMED   19075228
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF983315.1, AI789565.1 and AC109138.10.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026765.1, AK166519.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-472               CF983315.1         27-498
            473-715             AI789565.1         155-397
            716-1517            AC109138.10        139924-140725
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.83 cM"
     gene            1..1517
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /note="transmembrane protein 134"
                     /db_xref="GeneID:66990"
                     /db_xref="MGI:MGI:1914240"
     exon            1..240
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..654
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 134 isoform a"
                     /protein_id="NP_001072117.1"
                     /db_xref="GeneID:66990"
                     /db_xref="MGI:MGI:1914240"
                     /translation="MSAARPQFSIDDAFELTLEDAGPEPESSGVARFGPLHFERRARF
                     EVADEDKQSRLRYQNLENDEDGAQASPEPDGGVSTRDSGHMSVRSSQWSFSTISSSTQ
                     RSYNACCSWTQHPLIQKNRRVVLASFLLLLLGLVLILVGVGLEVAPSPGVSSAIFFVP
                     GILLLVPGVYHVIFIYCAVKGRRGFQFFYLPYFEK"
     exon            241..305
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            306..395
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            396..472
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            473..517
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            518..571
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            572..1517
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      917..922
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      942
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /note="major polyA site"
     regulatory      1487..1492
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
                     /note="hexamer: AACAAA"
     polyA_site      1503
                     /gene="Tmem134"
                     /gene_synonym="2410001H17Rik"
ORIGIN      
        1 tttggtgggc ggggccgtgg cgggctcaaa tggcggcggc gctgggcgcc taggccggcg
       61 ggggccatga gcgccgcccg gccccagttt agcatcgatg atgccttcga gctgaccctg
      121 gaggacgcgg ggcctgagcc cgagtccagc ggggtcgccc gcttcgggcc gctgcacttc
      181 gaacgccggg ctcggttcga ggtggctgat gaagacaagc agtcccggct acgctaccag
      241 aacctggaaa atgatgagga cggagcccag gcctctccgg agccggatgg gggagtcagc
      301 accagggatt ctgggcacat gtctgtccgc agctcgcagt ggtccttcag caccatcagc
      361 agcagcacac agcgctccta caacgcctgc tgcagctgga cccaacatcc tttgatccag
      421 aaaaaccgcc gggtagtgct ggcctccttc ctgcttctgc tgttggggct agtgcttatc
      481 ctggtcggcg tgggactgga ggtggccccc tctccaggtg tctccagtgc catcttcttt
      541 gtgccgggca tcctgctgtt agtcccagga gtctaccatg tgatcttcat ctactgcgct
      601 gtcaagggcc gccggggctt ccaattcttc tacctgccct actttgagaa gtgagctgca
      661 actggccagt ggctcaccag tgatccaagg cctcaggtca cctccacgtg tccacagggt
      721 attcctccaa cctacacctg gttctgttcc tttcacctgg aaggcagagg cccctgggac
      781 cctcacaacc accaggcccc tttgaatttg ctcaggaagt ttagagcatg ccagcctggg
      841 aatattgcct cttacctgat gtgtgcctta acttattcct gggttctgga ctcctgggtt
      901 ggtgtaattt tgtgctaata aaagggtaat tatttccaac aaggacagtt gcactttcct
      961 gggccagcaa gcctggccca gcacactaac gaccacagtc ccctcctaca gagggactgt
     1021 gtgtaaagga cccacctaga gctctagagg accaccaact tcccaaggac aacctggatg
     1081 gcctcaggtg tgcccatggt caccattatg cccagggcag agctggatga agtagtccca
     1141 ccctgtctgc cttcatccct gaggagattc aacactgccc cctagccaag ggcaccaaga
     1201 agtgatgcag gcaccaggcc tagaggctgg taccctggtt cctgcctggc tctgtagcac
     1261 taggcagtca tgactgtcac taaatgtggg tcatgtgccc ctctacacac ccactgccct
     1321 attttctaga cccagaggtt gggagaagca gggagaggag ggggtaggat cacggcttct
     1381 cagccgagca gcacagtaac aaggcgatgc ttagagccac caactgtttg aaacagttca
     1441 agttcttaga aaattggggc cgctaataat gtctgaaact taaataaaca aaaataaaca
     1501 aaaccgagaa tctttaa
//
