LOCUS       NM_001190352            7997 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Mus musculus transmembrane protein 132B (Tmem132b), mRNA.
ACCESSION   NM_001190352 XM_915709 XM_979000
VERSION     NM_001190352.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7997)
  AUTHORS   Wang,G., Peng,S., Reyes Mendez,M., Keramidas,A., Castellano,D.,
            Wu,K., Han,W., Tian,Q., Dong,L., Li,Y. and Lu,W.
  TITLE     The TMEM132B-GABAA receptor complex controls alcohol actions in the
            brain
  JOURNAL   Cell 187 (23), 6649-6668 (2024)
   PUBMED   39357522
REFERENCE   2  (bases 1 to 7997)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7997)
  AUTHORS   Wang,Y., Herzig,G., Molano,C. and Liu,A.
  TITLE     Differential expression of the Tmem132 family genes in the
            developing mouse nervous system
  JOURNAL   Gene Expr Patterns 45, 119257 (2022)
   PUBMED   35690356
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119268.12 and AC100382.22.
            
            On Mar 27, 2023 this sequence version replaced NM_001190352.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777535.2490901.1,
                                           SRR14777534.1404941.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849379, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-306               AC119268.12        67001-67306
            307-1198            AC119268.12        157077-157968
            1199-1345           AC119268.12        172798-172944
            1346-1532           AC100382.22        96946-97132         c
            1533-1676           AC100382.22        46318-46461         c
            1677-1882           AC100382.22        16854-17059         c
            1883-2153           AC100382.22        12096-12366         c
            2154-2345           AC100382.22        9664-9855           c
            2346-7997           AC100382.22        3113-8764           c
FEATURES             Location/Qualifiers
     source          1..7997
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 64.27 cM"
     gene            1..7997
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /note="transmembrane protein 132B"
                     /db_xref="GeneID:208151"
                     /db_xref="MGI:MGI:3609245"
     exon            1..306
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..3482
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /codon_start=1
                     /product="transmembrane protein 132B precursor"
                     /protein_id="NP_001177281.1"
                     /db_xref="CCDS:CCDS57384.1"
                     /db_xref="GeneID:208151"
                     /db_xref="MGI:MGI:3609245"
                     /translation="MRAPAASLGLLLALSALRCAESTGRGAADSLQRFSSLPAYLPAG
                     FHVTDAEEAFFLKEANQDLMRNASLQARSATLFIHRAQSPPAINASYGPFSVEKTVPW
                     DFLLMPTPFGNMERFPFNWRLKSHILDSSIFSNRPKVQTLFYVTGMGWDENDPGDDLP
                     CVKMFAFPEAREVAASCRLQGAPGLCVAELELLPEWFSSGLDLEPQEEIPALLGGTAM
                     ELYFALYPANEAGQCPLEEEGKWENNIHSEQEEPQPVLPARERIGSVVVYPTQDDLRW
                     SLVTLDDNVALSIPLNLIREGDTATFLVSLTSGSLAEKFTLRIKAAAGVKITAVRVSH
                     EDQWAVQEEIEQDGTQTTAVLSCMGHHPDTQSRANGSFYEILQVDFGVDNSSSLAGAQ
                     QITWQVEYPVEDSMSELFVSEIFISQTTFVGIVPLTMDTEILNTAILTGKPVSVPVKV
                     VGVQEDGSVVDVLESVECRSADEDVVKVSNTCDSIFVNGKEMKSKVGTIVNFTHQHFT
                     SQVEITVWVPRLPLQIEISDTELSQIKGWRIPVASNRRPTRESDDEEDEEKKGRGCTL
                     QYQHALVRVLTQFVSESPDLGQLTYMLGPDWQFDITNLVTEFVKVEEPKIAQLQNGRI
                     LAGREPGITTVQVLSPLSDSILAEKTVIVLDDRVTITELGVQLVAGLSLSLQPHRADK
                     RAIVSTVAAQDVLQAPQQEAIVSSWILFSDGAVTPLDIYDLKDFSVTVSSLDEMVVSV
                     QPNLQTRWPIVVAEGEGQGPLIKLEMSISESCQKNKRKSTLAVGKGNVKVRFEPGMHE
                     QQGGSNDIGGINREYKGHLSNSIEREGSQERAAQEWFQHGTPVGHEDRTNKSTTPQSP
                     MGGKLLKAGADAFTSFPTQGKLPESSNPGDLTMTSRGLTDLEIGMYALLCVFCLAILV
                     FLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDITLPSEECTTMI
                     DRGLQFEERNFLLNGSSQKTFHSQLLRPPDYVYEKELKNEPMGSSGPKRKRVKFTSYT
                     TILPEDGGPYTNSILFDSDDSIKWVCQDMGLGDSQDFRDYMERLQDQM"
     exon            307..1198
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1345
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1532
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1676
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1882
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..2153
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            2154..2345
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..7997
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7974..7979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /note="hexamer: AATAAA"
     polyA_site      7997
                     /gene="Tmem132b"
                     /gene_synonym="mKIAA1786"
                     /note="major polyA site"
ORIGIN      
        1 actctcgcgc tggctggagg ggcggccggc agctggcgct ggccgaggcg gcggcgggat
       61 gggacgcgcg ctggggcgca ggagccgcgg cgccggcggg ggccgcgcaa ctccggccaa
      121 gtgcagggcg ggcgcgcgct gagcccgggc gccgtctgca gccggcggcc gagcgcggag
      181 ctgagaggtg cgggaggcgg cggcgcagga gcgagcggag cccggcgccg gctcccggga
      241 ggaccatgcg ggccccggcc gcgtcgctcg ggctgctgct ggcgctgagc gcgctccgct
      301 gcgcagagag cacaggtcga ggcgctgcag acagcctgca gaggttttct tccctgcccg
      361 cctatctccc agccggcttc cacgtcaccg atgcagaaga ggctttcttc ctcaaggagg
      421 ccaaccagga cctcatgcgc aatgccagcc tgcaggcccg atccgccaca ctcttcatcc
      481 accgagccca gagccctccg gccatcaatg ccagctacgg tcccttctca gtagagaaga
      541 cggtgccctg ggacttcctg ctcatgccca ctcctttcgg aaatatggag aggttccctt
      601 tcaactggag gctcaaatcc catatcctcg acagctccat cttttccaac agacctaaag
      661 tgcagacact gttctatgtc actggcatgg gctgggatga aaatgaccct ggggatgatc
      721 ttccgtgtgt caagatgttt gccttcccag aggccaggga ggtggcagcc agctgccggc
      781 tgcagggggc tcctgggttg tgcgtggcag agctggagtt gttgcctgag tggttcagct
      841 caggtctgga ccttgaacct caagaggaga tcccagcatt gctgggtggc acagccatgg
      901 aactctactt tgcactttat ccagccaacg aggctggcca gtgcccactg gaggaggagg
      961 gcaaatggga aaacaatatc cactcagaac aggaggagcc tcagccagtg ctccctgctc
     1021 gggaaaggat cggcagcgtg gtggtctacc ctacccagga tgacctgcgg tggtccttgg
     1081 tgaccctcga tgacaatgtg gccctttcga tccctctgaa cctcatccga gaaggggaca
     1141 cggccacctt tttggtttct ctcaccagtg gctccctggc agagaagttc actcttcgaa
     1201 tcaaggcggc tgcaggtgtg aagataacgg ctgtgcgggt gagccacgag gaccagtggg
     1261 cagtgcagga ggagattgag caggacggta cccagaccac ggctgtcctg tcctgcatgg
     1321 gccaccaccc ggacacccag agcagggcaa acggctcctt ctatgagatt ctgcaagtgg
     1381 actttggagt cgataacagc agcagccttg ctggggccca gcaaatcacc tggcaggtag
     1441 aatatcctgt ggaagactcc atgagtgagc tcttcgtctc tgagatcttc atcagccaga
     1501 cgacctttgt gggcattgtc cctctcacca tggacacaga aattttgaac accgccattc
     1561 tcactgggaa gcccgtctcg gttcccgtca aggtcgtggg ggttcaagaa gatggatctg
     1621 tggtggatgt gttggagtct gtggaatgca ggtctgccga tgaagatgtt gtgaaggtct
     1681 ccaacacctg tgattctatc tttgtgaacg ggaaggagat gaagagcaaa gtgggcacga
     1741 ttgtcaactt cacccaccag cacttcactt cccaggtgga gatcactgtc tgggtgcccc
     1801 gcctgccgtt gcagattgag atctctgata cggagttgag ccagatcaag ggctggagga
     1861 tcccagtggc atccaacagg agacccaccc gggaaagtga tgacgaggag gatgaggaga
     1921 agaaggggcg agggtgtacc ctgcagtacc agcatgccct ggtgcgtgtc ctcactcagt
     1981 ttgtatctga gtcacctgac ctgggtcagc tgacctacat gctgggccct gattggcagt
     2041 ttgacatcac caacctggta accgagtttg tgaaggtgga ggagccaaaa attgcccagt
     2101 tacagaatgg caggatcctg gcaggacggg agccgggcat caccactgtg caggtcctct
     2161 cgcctctctc tgactccatc cttgcagaga agacggttat tgtcctcgat gaccgggtca
     2221 ccatcacaga gctgggtgta caactggtgg ctggcctgtc cctttccctg cagcctcaca
     2281 gggcagacaa aagggccatc gtctccacgg tggctgctca ggacgttctc caagccccac
     2341 agcaggaagc catagtcagt tcttggattt tgttcagtga tggcgctgtg acacctttag
     2401 atatttacga tctcaaggat ttctcagtga ccgtttcctc attggacgag atggtggtgt
     2461 ccgtccagcc aaaccttcag accagatggc caatcgtggt tgccgagggt gaaggacaag
     2521 ggcccctgat caagctggaa atgtccatca gcgagtcttg tcagaagaac aagaggaaga
     2581 gtacccttgc cgtgggcaaa ggaaacgtca aggtgaggtt tgaacctggg atgcacgagc
     2641 agcaaggagg cagcaatgac atcggtggca taaaccggga gtacaaaggc catctcagca
     2701 attccataga gcgcgaggga agccaggagc gagcagccca ggagtggttc caacacggca
     2761 caccggttgg ccacgaggac aggaccaaca agagcacaac cccacagtct ccaatgggag
     2821 gaaaactcct caaagcggga gcagatgcct tcaccagctt ccccacccaa gggaagttac
     2881 cagaatccag taaccccggt gacctcacga tgacctccag ggggttaacg gatttggaga
     2941 tcggaatgta cgccctgctc tgtgtcttct gcttggccat cttggtcttc ctgatcaact
     3001 gcgtggcctt tgcttggaag tataggcaca aaaggttcgc ggtgagcgag caaggcaaca
     3061 tcccgcattc tcacgactgg gtgtggctcg ggaatgaggt agagctcctg gagaaccctg
     3121 tggacatcac tctcccctcg gaggagtgca caaccatgat tgacaggggt ctgcagttcg
     3181 aggagaggaa cttcctgctg aatggcagct cccagaagac tttccatagt caactgctta
     3241 gaccccctga ctatgtgtat gagaaagagc tgaaaaatga acctatgggt tcctccggcc
     3301 caaagaggaa gagagtcaag tttacttcct acaccaccat cctccccgag gatgggggcc
     3361 catacaccaa ctctatcctg tttgacagtg atgacagcat caagtgggtc tgccaggata
     3421 tggggctggg ggactcgcag gacttcagag actacatgga aagactacag gaccagatgt
     3481 aaagtccttt cttaagtttg tattcacctt tatgccttct gttttctgag cgatggaaca
     3541 gtgggtctga tcagcaatag ggggtgactc aacaaagtgt cagagtgggg gggtgtctgg
     3601 agggatccct ctctaagtgg gtatcagcag cctggagggc tcaggctcaa gctaggtgat
     3661 gtctgtcaca ctggctcctg gggatgggag acattcagag acagcagcct ggcggtagac
     3721 acgaccccac agacactgtt agtcacctca tgaccaatgg ccgtgtgtaa tcaggagtgt
     3781 tctggatggt gatttttttt tctctatttc tagccctttt aaagcacagt ggacactcat
     3841 tgcgcgtggc ctgagttcaa atctatgtgg tggaagatga gtgagtgtag cctccttagc
     3901 tgtcaggagt aaggctcatt atttttatat acatctggac ttgcacctgt tcttttgacc
     3961 ttacattttt tttttgaggg ggaggggttg tttcggaagc acttaaagaa gagcttgttt
     4021 gatgttcctt gtttattccc tggagctcat tgtgtcttgc catacggagt ctccatacag
     4081 gatatcatat atatatatat ttttaacttt gttgctgagg acagtgttgt ctctccttca
     4141 tgacattggt atttctcatc tatcttggga acaggggtct gactggagac ctaggagagg
     4201 gttttttaaa aattttccac atgaaattta acatatttag agaaaagttc tgtcacaaac
     4261 atgttttgtg tcgtctactt gttagttgtt tgtgaatctc ctgggggtac agttctgagg
     4321 gaagaaaggc tccaatacca caatatggat ataagtcctc tgtgctcaat gcaatgtatt
     4381 aattcaaaca aacaaacaaa caaacaaaca aacaaaaaca ggactgaggg gctggagaga
     4441 tggcttggtg gttgagagta cttgttgctc ttgtagagga cccggagttc agatcatagc
     4501 acccacatgg tgactcacaa ccttctgtta actccagctc catgggatct gatgctctct
     4561 tctggcctct gtgggtacta cactcaagcg tgaatacaca gacacacatt cacataactt
     4621 aaaaaaagca aacaaacaaa tctttcaaaa atcaggattc atttatacaa caaagatatg
     4681 aagagatagc tttgtatgaa actctccact ttgcagatga attttaaaaa aaataatgtt
     4741 tcaaattagc aacatagaga agtcatccat acaatgactg aaaaaaaaaa aatctctgtt
     4801 gtcattcaga tagagaagaa agcatctcaa acatcttttc atagagaaaa caatggtttc
     4861 cccaacttca taattatcaa tgactgtccc agagcccaag gatcaccttt tacaaacaaa
     4921 gcacggaatt aaaaagattt ttgcataatt tccaataaaa gtgctgttta taagcatcat
     4981 gaatagcctt gagaaagaca gggatttttg gcttagccaa atgtgacatt tttgtttatc
     5041 ataatggtgt aactagaaaa gcagatacta gactagtatg cctcatggtg aactaactga
     5101 gccattgtca gctctcaaaa aatgggattt ttaaaggccc aaagcctgaa gcacatgcag
     5161 gaggtcactg atgtcaaagg gctgacctct gaacctctca aggagacttt ttcttattcc
     5221 tctgctctca ttttatacat gtccaggctg gaaacgtggc agccgtgcct ccggtagcca
     5281 tgatgggaca gctaagatgt tctccctgcc tctcccaccc ccagcactgc aatgtgctta
     5341 caaacagggc tgggcatgca ggtcctatgc tatatccccc agaagtatgt tcgcttgctt
     5401 ttgtgtttag aatggctcct gggaatggaa ggtactgact aaagaaggaa gctggaacat
     5461 acaggcattg catgaacttg gctgacatat gctactgcca agagctctct ggttagctgg
     5521 ctgtttctgg aaaggctgga gcagagctgg tagtcccaaa acacctgtgc agagcagcag
     5581 atttaccaat acgtttcaga tcctttttat gagccattta aagtcctatc ttccatcaca
     5641 gaaataatgg gaactcattt ctgaaagtga ggtccctccc tggaagcaag gacacacaaa
     5701 gcagactgcc tcctcttggt ttaggtgggg ccttgggtta gcctgtaatt tagcaggaaa
     5761 ttaccaaggg tgatacaagt aagcattgct tgtgattgac aggctttcaa tgcgggtggg
     5821 gctcagaggg cagaggagct gactatggtc ctgaagatgt ctccactgcc ctcttagaca
     5881 tactcagtga attagcttct gtgcacattc acggtgttgt tgtgttagga caccatcagt
     5941 ttaaatcaaa gttgagtggc aggttctgat ggaaagctcc cttttaacat atatgcagac
     6001 acatatatac agacatatat gcagacacat atatacagac acagatatgc acgtgtaccc
     6061 acatctgtgc gtgtggatac caaggtgtca cagactcagt catttgctgg gaatctaaag
     6121 agcctgtcag tcattctcag actcaccttg ggaagggctc agcatcgcag tgtcatagaa
     6181 acatcttaag ccctaactgt cccttgtagg ctataaactg tggctatctc agattatgtg
     6241 gcttacttga tttttttcat caagcaagct atgatttctg tgttagcctc tgaaatacat
     6301 ggactagaat gagggagata gcataaacta tcaagcctta aaatcaaaat ctccagggcc
     6361 ctgcatttgc ctggatttca gttttcatgg ctgagatatc taaattataa ctcttgataa
     6421 ataatctgat ccagatgtgc gttatcgagt cctttcctct gccatgagag tgatgcttgt
     6481 gagaatagat tcttcctggg ggagttagga gagggcaaag gttgtgagct ctttggccat
     6541 acagagggag gttgatgcat gagatgggca aaggttgtgt gacctgggac attcagagac
     6601 aatgcagtga ccatcttcag gatttgtatg tgatgctttt ggggttaagg tatagggact
     6661 ttggaggtag gtgccacatg aaaggactgg agctggggga taggtgtgct ggacttaaga
     6721 gactcaaata cagtgggata tttggccaga agagcaacat gtaaacaatg tcagaaaact
     6781 atctacctag cacactggcc agttgcatgg ttttcccaga ccctggcaat tcttaaccat
     6841 ctagatggga agtttctact tacagacatg aatacggcca atacatgcat tgattctgtt
     6901 ttactctctt ggccacacct atggactgaa gtaatttgca cctcatttaa ggtttaggaa
     6961 gccacctttg ggtattctca tcaacctttt tgtttgtttg tttcattctt ttgggggctg
     7021 gagaggagag agaaagctca gccagtagaa tttgctgcat aagcccaagg attggaattt
     7081 gactctcagc atccacataa aaatccaggc gcagtgggtg gtgtatgctt ataatcccag
     7141 cacacgggga atcagagaca ggcagacacc tgagacttca tttctagtca gcctaattgg
     7201 caagttccag gtccaagtca gaggtcctgt ctcaacacac acagagagag agagaggggg
     7261 gggagaatta aaatgaaggg gctttccaat agtgggacca cactgaagct gtgcccatca
     7321 gtgaggagtc tcccagtccc cagcagtgac catagacagt gttttctgaa tcctatcttt
     7381 agcccattgg gttttctact ctggtcactt aaagagggtc acatttctca attcaggtca
     7441 ctgtaaatga caccatggat ggtttataaa ccgttccttt ctccttcatc aaaactgtat
     7501 ttgtataatg caatgcatct cacctgtcac atagagggtg gatggtggga cagagttttg
     7561 ctgaattaca gaacagcagc tatttttgta tgtaatatag gcaatataac gaagctgtga
     7621 acggtgtatt ggaataaata catttaaaaa taaaagcatg tgaaaatgta gctcttaagt
     7681 gtacagacat ccagctcaac aatatttaaa cggatgatgg gaaaagtttt ggggcctgac
     7741 gttgaacaat acaccatgtt aggaattctg acctggaagg acattgtggc tctcatgctg
     7801 ggattgtcga tggaatcttc cagaacattt tgatcttact cctcattact ttctgatttt
     7861 ttttcctccc tcctcccacc ccacaatgga aatatttcag aaataaaatg acttcatttt
     7921 tcagcataaa ggtatattct aaccacaggg taactcgtca tttttaacat ggaaataaac
     7981 atttgaacat tcttcaa
//
