LOCUS       NP_808403                419 aa            linear   ROD 04-JUN-2024
DEFINITION  transmembrane protein 130 precursor [Mus musculus].
ACCESSION   NP_808403
VERSION     NP_808403.2
DBSOURCE    REFSEQ: accession NM_177735.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 419)
  AUTHORS   Turrero Garcia,M., Stegmann,S.K., Lacey,T.E., Reid,C.M.,
            Hrvatin,S., Weinreb,C., Adam,M.A., Nagy,M.A. and Harwell,C.C.
  TITLE     Transcriptional profiling of sequentially generated septal neuron
            fates
  JOURNAL   Elife 10, e71545 (2021)
   PUBMED   34851821
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 419)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 419)
  AUTHORS   Loo,L., Simon,J.M., Xing,L., McCoy,E.S., Niehaus,J.K., Guo,J.,
            Anton,E.S. and Zylka,M.J.
  TITLE     Single-cell transcriptomic analysis of mouse neocortical
            development
  JOURNAL   Nat Commun 10 (1), 134 (2019)
   PUBMED   30635555
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 419)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC131728.4.
            
            On Apr 2, 2004 this sequence version replaced NP_808403.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067004.1, SRR9219383.120115.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 84.76 cM"
     Protein         1..419
                     /product="transmembrane protein 130 precursor"
                     /calculated_mol_wt=43969
     sig_peptide     1..25
                     /note="/evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6NXM3.1)"
                     /calculated_mol_wt=2677
     mat_peptide     26..419
                     /product="Transmembrane protein 130. /id=PRO_0000278277"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6NXM3.1)"
                     /calculated_mol_wt=43969
     Site            29
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6NXM3.1)"
     Site            85
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6NXM3.1)"
     Region          <174..207
                     /region_name="PKD"
                     /note="PKD domain; pfam00801"
                     /db_xref="CDD:395646"
     Site            194
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6NXM3.1)"
     Region          264..309
                     /region_name="PKAT_KLD"
                     /note="PKAT, KLD domain; pfam20433"
                     /db_xref="CDD:466582"
     Site            337..357
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6NXM3.1)"
     CDS             1..419
                     /gene="Tmem130"
                     /gene_synonym="C130036G08"
                     /coded_by="NM_177735.4:47..1306"
                     /db_xref="CCDS:CCDS19851.1"
                     /db_xref="GeneID:243339"
                     /db_xref="MGI:MGI:3607706"
ORIGIN      
        1 makatdvlvf wfacllllgp arvaaglynl sltadgpatv gtevtisasl evkdngslpl
       61 padthlyrfh wihtpltlta kneknltsti hvvggvpgdf pisvwvtavd cwvcqplars
      121 tlllpikesl vgnivvtqnt slswpnsyit krslrlsfll hdpsdffksa sffyrwdfgd
      181 gtllitdnpv vyynysspgt ftvkvrvvae weqikpdttk gtiqktgdfs asldlreslq
      241 giqilgptll qtfqkltmnl nffgspplhv cwglkpqclp ledrechavl vtrtsfnlth
      301 vfqdpgdycf ifraenaisk ahqyhriqvw pssfqpfvfa fpcatlitvl lvflmymtvr
      361 saatqkdive spgatglkcc cqvccgslfl dspseyleiv renhgllppl ykpvktynv
//
