LOCUS       NM_153776               1613 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 121 (Tmem121), mRNA.
ACCESSION   NM_153776
VERSION     NM_153776.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1613)
  AUTHORS   Nesset,A.L. and Bader,D.M.
  TITLE     Hole is a novel gene product expressed in the developing heart and
            brain
  JOURNAL   Mech Dev 117 (1-2), 347-350 (2002)
   PUBMED   12204283
  REMARK    GeneRIF: Mouse hole is not expressed in the developing heart,
            although it does share neural expression seen in the chick.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY325504.1 and BC043474.1.
            
            On Mar 24, 2007 this sequence version replaced NM_153776.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF488729.1, AK010454.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                BY325504.1         2-73
            73-1613             BC043474.1         30-1570
FEATURES             Location/Qualifiers
     source          1..1613
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 61.76 cM"
     gene            1..1613
                     /gene="Tmem121"
                     /gene_synonym="2410008J05Rik; Hole"
                     /note="transmembrane protein 121"
                     /db_xref="GeneID:69195"
                     /db_xref="MGI:MGI:1916445"
     exon            1..56
                     /gene="Tmem121"
                     /gene_synonym="2410008J05Rik; Hole"
                     /inference="alignment:Splign:2.1.0"
     exon            57..1601
                     /gene="Tmem121"
                     /gene_synonym="2410008J05Rik; Hole"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..1198
                     /gene="Tmem121"
                     /gene_synonym="2410008J05Rik; Hole"
                     /note="protein hole"
                     /codon_start=1
                     /product="transmembrane protein 121"
                     /protein_id="NP_722471.2"
                     /db_xref="CCDS:CCDS26206.1"
                     /db_xref="GeneID:69195"
                     /db_xref="MGI:MGI:1916445"
                     /translation="MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCII
                     VLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARR
                     GAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDL
                     LDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYP
                     VLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPP
                     PALALELQPPPSQRNSVPPPPPLHGPPVRPHGPSPTRDALDT"
     polyA_site      1601
                     /gene="Tmem121"
                     /gene_synonym="2410008J05Rik; Hole"
                     /note="major polyA site"
ORIGIN      
        1 gggcccggcg cggaggctcg gcggggccgg ccggcgcgct gcatctggcc ggccgggttc
       61 cgagctcgcc ggccgggagc agcagcgctc tccgggcaag tggacaagcc ccgcgccccg
      121 ctgcgctgcg ccatgccgga gggctgagct ttggggcccg ctgctctttg ggacacagca
      181 ggacctcgtc ccttggcgcc ttgggactgc gcgcgccagg gcggagcccg ggccgctgac
      241 catggtgctg cctcctccag accggcgcca cgtgtgcctg accacgctgg tgatcatggg
      301 cagtatggcc gtcatggacg catacctggt ggagcagaac cagggcccgc gcaagattgg
      361 cgtgtgcata attgtgttgg taggcgatgt gtgcttcctg ctggtgctgc gctatgtggc
      421 cgtgtgggtg ggggccgagg ttcgcacggc caagcgtggc tacgctatga tcctctggtt
      481 cctctacatc ttcgtgctgg agatcaagct ctatttcatc tttcagaact acaaggctgc
      541 gcggcgcgga gcggccgacc cagtggctcg caaggcgttg acactgctac tgtctgtgtg
      601 cgtgccaggc ctgttcctgt tgcttgtggc actagaccgc atggaatatg tgcgcacctt
      661 ccgaaagcgc gaggacctgc ggggccgcct cttctgggtg gctttggatc tgctggatct
      721 gctggacatg caggccaacc tctgggagcc gccacgcact gggttgccac tgtgggccga
      781 aggcctcacc tttttctatt gctatatgct gctgttggtg ctgccctgcg tagcgctcag
      841 cgaggtcagc atgcaagggg agcacatcgc accgcagaag atgatgctgt acccggtgct
      901 cagcctcgcc actgtcaatg tggtggctgt gctggctcgt gccgccaata tggcactctt
      961 ccgcgatagc cgagtctcgg ccatcttcgt aggcaagaac gtggtggcac tggccaccaa
     1021 ggcctgcacg ttcctcgagt accgtcgcca ggttcgcgat tttccaccac ctgcgcttgc
     1081 acttgagctg caaccaccgc cttcccagcg caactcggtg ccgcctcctc caccactgca
     1141 tggcccgcca gtgcgccccc acgggccctc acccacgcgg gatgcgctgg acacgtgaca
     1201 gccccccccc cccgcgcggg ccgcacagac gctggactaa ctgcgcgcgg tttgcatggg
     1261 atgggatggg gcaggctccc cttagggaca ggtgttgtga atgcatacct gtgcagtgcc
     1321 tgcggtgcct ggggccatgt ctgcttcttc atctcaggaa tctctcggac cacggactct
     1381 cagcctccac tccactagct cgcctcgatg caaaggcagc tggtgaggcc tggtcttgag
     1441 tggagatggc tcaacccctg cctgatgcgg ggctgccggg atgggagggc gggcagtgtt
     1501 ccaggagatc tggacctatg gtaggggctt ctggctcaga gtttggggcc aaagaggcct
     1561 ctgtcatttt aaagacttgt gtttacagtt ttgtacccaa aaaaaaaaaa aaa
//
