LOCUS       NM_001039723            1860 bp    mRNA    linear   ROD 20-DEC-2022
DEFINITION  Mus musculus transmembrane protein 120B (Tmem120b), mRNA.
ACCESSION   NM_001039723 XM_284126 XM_915376 XM_994813
VERSION     NM_001039723.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Beaulieu-Laroche L, Christin M, Donoghue A, Agosti F, Yousefpour N,
            Petitjean H, Davidova A, Stanton C, Khan U, Dietz C, Faure E,
            Fatima T, MacPherson A, Mouchbahani-Constance S, Bisson DG, Haglund
            L, Ouellet JA, Stone LS, Samson J, Smith MJ, Ask K,
            Ribeiro-da-Silva A, Blunck R, Poole K, Bourinet E and Sharif-Naeini
            R.
  TITLE     TACAN Is an Ion Channel Involved in Sensing Mechanical Pain
  JOURNAL   Cell 180 (5), 956-967 (2020)
   PUBMED   32084332
REFERENCE   2  (bases 1 to 1860)
  AUTHORS   Batrakou DG, de Las Heras JI, Czapiewski R, Mouras R and Schirmer
            EC.
  TITLE     TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important
            for Adipocyte Differentiation
  JOURNAL   PLoS One 10 (5), e0127712 (2015)
   PUBMED   26024229
  REMARK    GeneRIF: it is possible that the TMEM120A and B fat-specific
            nuclear envelope transmembrane proteins may play a contributory
            role in the tissue-specific pathology of this disorder or in the
            wider problem of obesity.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1860)
  AUTHORS   Thuret S, Bhatt L, O'Leary DD and Simon HH.
  TITLE     Identification and developmental analysis of genes expressed by
            dopaminergic neurons of the substantia nigra pars compacta
  JOURNAL   Mol Cell Neurosci 25 (3), 394-405 (2004)
   PUBMED   15033168
REFERENCE   4  (bases 1 to 1860)
  AUTHORS   Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng
            EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC,
            Babbitt PC and Ferrin TE.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ056274.1, AK158123.1, AK132283.1 and AC158114.8.
            
            [WARNING] On Apr 28, 2023 this sequence was replaced by
            NM_001039723.3.
            
            On Jun 1, 2006 this sequence version replaced NM_001039723.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132283.1, BC022593.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                CJ056274.1         1-42
            43-1394             AK158123.1         2-1353
            1395-1739           AK132283.1         1365-1709
            1740-1860           AC158114.8         115803-115923
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5"
     gene            1..1860
                     /gene="Tmem120b"
                     /note="transmembrane protein 120B"
                     /db_xref="GeneID:330189"
                     /db_xref="MGI:MGI:3603158"
     exon            1..221
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..1172
                     /gene="Tmem120b"
                     /codon_start=1
                     /product="transmembrane protein 120B"
                     /protein_id="NP_001034812.1"
                     /db_xref="CCDS:CCDS39262.1"
                     /db_xref="GeneID:330189"
                     /db_xref="MGI:MGI:3603158"
                     /translation="MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELTSLQTLCS
                     TSISKQKRHLKDLKHTLQRYKRHSSHEEAALIQQMTANIKERQNVFFDMEAYLPKKNG
                     LYLNLVLGNVSVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFVLHYRVTDEVF
                     NFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPNGLIYQKFRNQ
                     FLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLF
                     CGHFWQLYNAVTLFELSTHEECKEWQVFVLALTFLILFLGNFLTTLKVVHAKLHKNRN
                     KTKQP"
     exon            222..340
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            341..457
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            458..517
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            518..613
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            614..703
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            704..769
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            770..831
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            832..924
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            925..989
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1058
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1860
                     /gene="Tmem120b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgtcaggt gcgcgcgtgg ctccggctgc gcaggaacag ctggtgcctc gggaggcggc
       61 tagtgagcgg gcgggcgtgg gctgctggtg gccggacggg tcacgctgcg ggtttcgtcg
      121 ccgccgccgc cgccgccttg caccattgca ccatgtccgg ccagctggag cgttgcgagc
      181 gcgagtggca cgagctggag ggagaatttc aggagctgca ggagacacac aggatctata
      241 agcagaagct ggaggagctg acctccctgc agacgctgtg cagcacctcc atcagcaagc
      301 agaagaggca cctgaaggac ctgaagcaca cactccagag gtacaagcgc cattccagcc
      361 atgaggaggc ggcgctcatc caacagatga ccgccaacat taaggagcga cagaatgtct
      421 tctttgacat ggaggcctac ctaccgaaga agaatgggct ctacttgaat ctggttcttg
      481 gcaacgtgag cgtgaccctc ctcagcaatc aggccaagtt tgcttacaag gatgagtatg
      541 agaagtttaa gctctacctg accataattc ttcttctggg tgctgtggcg tgtcgatttg
      601 tccttcatta cagggtgacc gatgaagtct tcaacttcct gctcgtgtgg tattactgca
      661 ccttgaccat tcgagagagc atcctcatca gcaatggttc cagaatcaag ggctggtggg
      721 tgtctcacca ttatgtctcc acgttcctgt ctggagtgat gctgacttgg cctaatggac
      781 taatttacca gaagtttcga aatcagtttt tagcgttctc catttttcag agctgcgttc
      841 agtttctaca gtactattac cagaggggct gtctctacag actgcgggcc ctgggggaga
      901 ggaaccacct ggacctcaca gtggaagggt tccaatcctg gatgtggcgg ggcctcacct
      961 tcctcctgcc tttcctcttc tgtggccatt tctggcagct ctacaatgcc gtcaccctgt
     1021 ttgagctctc cacccatgag gaatgcaaag aatggcaggt attcgtgctg gctctcacct
     1081 tcctcatcct cttcctgggc aattttctga ccacgctcaa agttgtccat gccaaactcc
     1141 acaagaacag aaacaagaca aagcagccat gaacctccgg acccttgtgc cacctggggg
     1201 ccttgggacc taagactgct gggcgttcca gtcagcaccc tggctgccgg tcagtggtag
     1261 ccatgggcag caacatctca ggggccagca gcatcaccgg gagcagggcc aaggccccgg
     1321 tccccggcgg acatgaggaa tgtgaaggcc acctgcgcgc gcagtattaa cctgtcccag
     1381 ctccctattt ataacatatt taatatcggg tcttccctgc ttccctggaa tccgaggcct
     1441 gccttccctg gagctctgtg taatggccgt gggcaggcct gtgtctgtct ttcagggagg
     1501 ggccagaagc ctcagggaac ccctctcttc ctactcctat catttgaatc cctcactggg
     1561 gtttagatgt gcctcactcg agttggcttt agccgacctg ctactttact gtgtcccagg
     1621 caccgggagg aatgaaactt tgagcatcct gtggagcctc ccctgtcctg ggccaccacc
     1681 tcttctgtaa gcctcccaca gccccacctt ctgcggtgga caaatattta agttctcaga
     1741 gaacctacct gtgttgtctc ttgccttggt ctccggaacc gcaggcctgc tggccactgg
     1801 gggaaagaga tgcagcctcc ttgggacctc catgtggcag ggtgttaagg acgcggacgg
//
