LOCUS       NM_029070               1406 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus transmembrane protein 114 (Tmem114), mRNA.
ACCESSION   NM_029070 XM_979585
VERSION     NM_029070.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1406)
  AUTHORS   Sun,J., Lu,Y., Nozawa,K., Xu,Z., Morohoshi,A., Castaneda,J.M.,
            Noda,T., Miyata,H., Abbasi,F., Shawki,H.H., Takahashi,S.,
            Devlin,D.J., Yu,Z., Matzuk,R.M., Garcia,T.X., Matzuk,M.M. and
            Ikawa,M.
  TITLE     CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or
            epididymis-enriched genes individually dispensable for male
            reproductiondagger
  JOURNAL   Biol Reprod 103 (2), 183-194 (2020)
   PUBMED   32588039
REFERENCE   3  (bases 1 to 1406)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1406)
  AUTHORS   Maher,G.J., Hilton,E.N., Urquhart,J.E., Davidson,A.E.,
            Spencer,H.L., Black,G.C. and Manson,F.D.
  TITLE     The cataract-associated protein TMEM114, and TMEM235, are
            glycosylated transmembrane proteins that are distinct from claudin
            family members
  JOURNAL   FEBS Lett 585 (14), 2187-2192 (2011)
   PUBMED   21689651
REFERENCE   5  (bases 1 to 1406)
  AUTHORS   Mineta,K., Yamamoto,Y., Yamazaki,Y., Tanaka,H., Tada,Y., Saito,K.,
            Tamura,A., Igarashi,M., Endo,T., Takeuchi,K. and Tsukita,S.
  TITLE     Predicted expansion of the claudin multigene family
  JOURNAL   FEBS Lett 585 (4), 606-612 (2011)
   PUBMED   21276448
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK015757.1.
            
            On Apr 5, 2007 this sequence version replaced NM_029070.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK015757.1, BC027071.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1406              AK015757.1         2-1407
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 3.84 cM"
     gene            1..1406
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /note="transmembrane protein 114"
                     /db_xref="GeneID:74720"
                     /db_xref="MGI:MGI:1921970"
     exon            1..701
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /inference="alignment:Splign:2.1.0"
     CDS             485..1153
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /note="claudin-26"
                     /codon_start=1
                     /product="transmembrane protein 114"
                     /protein_id="NP_083346.1"
                     /db_xref="CCDS:CCDS27937.1"
                     /db_xref="GeneID:74720"
                     /db_xref="MGI:MGI:1921970"
                     /translation="MRVRLGALAGAAALSGALSFVLLAAAIGTDFWYIIDTERLERSS
                     QRMRDQGPANRSQQEPLSSHSGLWRTCRVQSSCTPLMNPFWQENVTVSDSSRQLLTMH
                     GTFVILLPLSLIVMVFGGMTGFLSFLLRAHLLLLLTGILFLFGAMVTLTGISIYIAYS
                     AVAFREAVCLLEERALLDQVDIRFGWSLALGWISFVSELLTGVVFLAAARALSLSQRQ
                     DQAI"
     exon            702..782
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /inference="alignment:Splign:2.1.0"
     exon            783..920
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1406
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1406
                     /gene="Tmem114"
                     /gene_synonym="4930511J11Rik; Cldn26"
                     /note="putative"
ORIGIN      
        1 gtgagcccag tcttcttgag gtttcaggac gctcgccccg atccggagcg gtgggaagcg
       61 aagatagacg ccggctgaac tgggggcgcc gaggtagagg tgtggggaga acaaggagga
      121 ctgaggtcga cagaggcggg gagctgctgg aggggttcat ggagggtgag gcaggggagt
      181 ggaggcagta gtcgggggct ggggagaaga gtgcagagcc agaaaggagg agacgctgga
      241 acggggcgca agttggagct gcgagagcag gtggcacctg tgctagtcgg acccgggagg
      301 gtcgggaggc actagggtgg aggtctgcga ggacagggat ccctgaggac actgatttgg
      361 gccggagcac gtgcgggtgg gatcgcgtaa gtggagccag agatccacgc tggagaatct
      421 ggagtgcagc gaacagacgg ggagcgtggg caggagccgg cgcccggggg cccaacgctg
      481 ggagatgcgg gtgcgcctgg gcgctctggc gggagcggcg gcgctgagcg gggctctgag
      541 cttcgtgctg ctggcagcag ccatcggcac cgacttctgg tacatcatcg acaccgagag
      601 gctggaaagg agcagccaga ggatgaggga ccagggaccg gccaaccgca gccagcaaga
      661 gcctctgagc tcccactcgg gactctggag aacttgccgg gtccagagct cctgcacgcc
      721 gttgatgaac cctttctggc aggagaatgt gacggtcagc gactccagca gacagcttct
      781 cactatgcac gggacattcg tgatcttatt gccactcagt ctgatcgtga tggtgtttgg
      841 ggggatgacc gggttcttga gcttcctcct ccgagctcac ctccttctgc tgctcaccgg
      901 gatcctcttt ctctttggag ccatggtgac cctcactgga atcagcatct acattgcgta
      961 ctcagcagtt gccttccgag aggcagtatg cctcctggag gagagggccc tgctggatca
     1021 ggtggatata cgctttggct ggtctctggc cctcggctgg attagctttg tatctgagct
     1081 gctcactggg gtggtcttcc tggcagcggc gcgtgcgctc agcctgagcc agaggcagga
     1141 ccaagccatc tgagtttggc caacccagga ggcgcagggc cttttggacc catctcagtg
     1201 gatggcaacc ttttcttact caaataccat tgacagaagc cagaaagcca gtggtggctc
     1261 gctgaggatg agtgccccct ggctgctgtc tttgtgctat ctgggctgcc cagtctgctg
     1321 tgatgtgcgc atgtgtgtgc ttctggtagt ccggaagaga gggagtgtgg agcccttatc
     1381 acctgaaata aacaccaatc ctagtc
//
