LOCUS       NM_001033433            1941 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transmembrane protein 102 (Tmem102), mRNA.
ACCESSION   NM_001033433 XM_354618
VERSION     NM_001033433.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Ho,K.C., Chiang,Y.J., Lai,A.C., Liao,N.S., Chang,Y.J.,
            Yang-Yen,H.F. and Yen,J.J.
  TITLE     CBAP promotes thymocyte negative selection by facilitating T-cell
            receptor proximal signaling
  JOURNAL   Cell Death Dis 5 (11), e1518 (2014)
   PUBMED   25393474
  REMARK    GeneRIF: CBAP is a novel component in the TCR signaling pathway,
            and it modulates thymocyte apoptosis during negative selection.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1941)
  AUTHORS   Chiang,Y.J., Ho,K.C., Sun,C.T., Chiu,J.J., Lee,F.J., Liao,F.,
            Yang-Yen,H.F. and Yen,J.J.
  TITLE     CBAP functions as a novel component in chemokine-induced
            ZAP70-mediated T-cell adhesion and migration
  JOURNAL   PLoS One 8 (4), e61761 (2013)
   PUBMED   23620790
  REMARK    GeneRIF: CBAP indeed can function as a novel signaling component
            within the ZAP70/Vav1/talin complex and plays an important role in
            regulating chemokine-promoted T-cell trafficking.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1941)
  AUTHORS   Kao,C.J., Chiang,Y.J., Chen,P.H., Lin,K.R., Hwang,P.I.,
            Yang-Yen,H.F. and Yen,J.J.
  TITLE     CBAP interacts with the un-liganded common beta-subunit of the
            GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial
            dysfunction
  JOURNAL   Oncogene 27 (10), 1397-1403 (2008)
   PUBMED   17828305
  REMARK    GeneRIF: Shows functional evidence for the homologous human
            protein.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK143262.1, AL603707.5 and CK032079.1.
            
            On Jun 9, 2010 this sequence version replaced NM_001033433.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143262.1, ERR2844020.1362103.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AK143262.1         2-158
            158-158             AL603707.5         184696-184696       c
            159-580             AK143262.1         159-580
            581-581             AL603707.5         184273-184273       c
            582-652             AK143262.1         582-652
            653-653             AL603707.5         184112-184112       c
            654-1933            AK143262.1         654-1933
            1934-1941           CK032079.1         620-627
FEATURES             Location/Qualifiers
     source          1..1941
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.88 cM"
     gene            1..1941
                     /gene="Tmem102"
                     /gene_synonym="4632403M07Rik; Cbap; Tmem102-ps"
                     /note="transmembrane protein 102"
                     /db_xref="GeneID:380705"
                     /db_xref="MGI:MGI:1921591"
     exon            1..605
                     /gene="Tmem102"
                     /gene_synonym="4632403M07Rik; Cbap; Tmem102-ps"
                     /inference="alignment:Splign:2.1.0"
     exon            606..1941
                     /gene="Tmem102"
                     /gene_synonym="4632403M07Rik; Cbap; Tmem102-ps"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1917..1922
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmem102"
                     /gene_synonym="4632403M07Rik; Cbap; Tmem102-ps"
                     /note="hexamer: ATTAAA"
     polyA_site      1941
                     /gene="Tmem102"
                     /gene_synonym="4632403M07Rik; Cbap; Tmem102-ps"
                     /note="major polyA site"
ORIGIN      
        1 gctttctgtc caccaccttt gaagctaccc cttcatcgga aagccgcgga ccaataagcc
       61 cttctcaaaa agaggtaaag ggaggtgggc aaaggctcgt ggtaaagatt ggctattgta
      121 ttcccaggag ggaccaaata gccttttttt ttttttttaa cctgctgagt caggtgaacc
      181 gatttaccgt ggggcaacct gcttagaaaa aaccgaaggc aatagtcatt tgttcatcag
      241 gaagactaaa tacagatcac atcatctcca agacccactt gtggcctgtc tgtaaccctt
      301 gatctgcctc agagggaggg gaaaactgga caagtttggg gccgcaaaag aaaggcctgc
      361 caaagctaac tgcaccaaac gctagcgaag catggcttcc accgtctggg ggggtgcccc
      421 ctggtgggga ccaccgcccc cagccccagc ccggcctctc acagacatag atttctgctc
      481 gggcgcccag ctgcaggagc tcactcagtt aattcaggag ctccgtgttc aggagagttg
      541 gagtgaaggg cccaagcctg gagctgatct tctccgagcc aaggattttg tcttcgctct
      601 actcggtctg gttcaccgcc aagaccctcg ttttccaccc caggcagaac tcttgctgct
      661 tcgtggtggg attcgcgaag gttccctaga tttagggcac gcccccttag gtccctactc
      721 ccggggacct cattatgatg ccggctttac actccttgtg cctgtgtttt ctctggatgg
      781 cactgggccc gagctgctac tggatctgga atcctgttct gcatggctcc gccttccaga
      841 actgatgcgt ggaattttgg tccgggaggc ctggcaggat tgcttaggac ctcctgtccc
      901 agaagaaagt gatatgactc accaaaccca tagcaaagag agtcccaccg accgggaaaa
      961 ctctgtagat ccgtcacatg attatgtccc tgaacctgag ccacacatgt ctttgcaaaa
     1021 atcatctagt gacctttcag agtcccaatc gtcttataag gacattacca atcctgaaac
     1081 tcctgagcca ttggaaacac tgagcagcga cgccttggac gccgacgaaa gccaagtccc
     1141 aaagccgtcg gaggctccaa aggcatggcc cacattatgc ccgacccaag taacttcctg
     1201 gttcttcgtt aagttggctg aggttgctga gtccctgatc ccggtcccag gcgccccacg
     1261 gctagttcat gcagctcgtc acgcaggtgt caccacggtc ctcctggcaa ctccagagcc
     1321 cccacgccac ctcctgctct tcgacttgat cccggtggtg accgtgacag gctggcctga
     1381 cacggctcgg agccactcgt gggcgggtcc actggtctct gaatcggcct ctttctacct
     1441 agtgccgggc agcctcccag agcagccgag cacctctgga tggcagctgt gcttcgctcg
     1501 ccaggagctg gcgctcaaag agcgcatccc cacgccgctg cttcaggcac acgcggcggc
     1561 ccaggcgctg ctgcgcccgc tggtggcggg gacccgagcc gctgcgccct acctcctgcg
     1621 gaccttgctc tactgggcgt gcgagcggct cccggcgctc tacttggcgc ggccggaaaa
     1681 tgccggcgct tgttgccttg ggctactgga tgagctgagc cgagtgctag aggccggggc
     1741 gctgcctcat tattttttga gcggccgaaa gctccgtgtg ggagacggct ccgctgctct
     1801 gcgcggggca ttggcccagc tccgcgggga ccctgcacag gccttgcgtg aggctgtaga
     1861 ggaagccaag gttgcccgca aagggggcgg tttagcgggc gtagggggcg ggacccatta
     1921 aagattttac tcctaaggga a
//
