LOCUS       NM_026433               1764 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transmembrane protein 100 (Tmem100), mRNA.
ACCESSION   NM_026433
VERSION     NM_026433.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1764)
  AUTHORS   Nees,T.A., Wang,N., Adamek,P., Zeitzschel,N., Verkest,C., La
            Porta,C., Schaefer,I., Virnich,J., Balkaya,S., Prato,V.,
            Morelli,C., Begay,V., Lee,Y.J., Tappe-Theodor,A., Lewin,G.R.,
            Heppenstall,P.A., Taberner,F.J. and Lechner,S.G.
  TITLE     Role of TMEM100 in mechanically insensitive nociceptor un-silencing
  JOURNAL   Nat Commun 14 (1), 1899 (2023)
   PUBMED   37019973
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1764)
  AUTHORS   Wang,P., Zhang,Q., Dias,F.C., Suttle,A., Dong,X. and Chen,Y.
  TITLE     TMEM100, a regulator of TRPV1-TRPA1 interaction, contributes to
            temporomandibular disorder pain
  JOURNAL   Front Mol Neurosci 16, 1160206 (2023)
   PUBMED   37033371
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1764)
  AUTHORS   Wang,G., Wen,B., Deng,Z., Zhang,Y., Kolesnichenko,O.A., Ustiyan,V.,
            Pradhan,A., Kalin,T.V. and Kalinichenko,V.V.
  TITLE     Endothelial progenitor cells stimulate neonatal lung angiogenesis
            through FOXF1-mediated activation of BMP9/ACVRL1 signaling
  JOURNAL   Nat Commun 13 (1), 2080 (2022)
   PUBMED   35440116
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1764)
  AUTHORS   Gresakova,V., Novosadova,V., Prochazkova,M., Prochazka,J. and
            Sedlacek,R.
  TITLE     Dual role of Fam208a during zygotic cleavage and early embryonic
            development
  JOURNAL   Exp Cell Res 406 (2), 112723 (2021)
   PUBMED   34216590
REFERENCE   6  (bases 1 to 1764)
  AUTHORS   Georgas,K.M., Chiu,H.S., Lesieur,E., Rumballe,B.A. and Little,M.H.
  TITLE     Expression of metanephric nephron-patterning genes in
            differentiating mesonephric tubules
  JOURNAL   Dev Dyn 240 (6), 1600-1612 (2011)
   PUBMED   21491542
REFERENCE   7  (bases 1 to 1764)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 1764)
  AUTHORS   Moon,E.H., Kim,M.J., Ko,K.S., Kim,Y.S., Seo,J., Oh,S.P. and
            Lee,Y.J.
  TITLE     Generation of mice with a conditional and reporter allele for
            Tmem100
  JOURNAL   Genesis 48 (11), 673-678 (2010)
   PUBMED   20848592
  REMARK    GeneRIF: Tmem100 was predominantly expressed in arterial
            endothelial cells of developing embryos.
REFERENCE   9  (bases 1 to 1764)
  AUTHORS   Georgas,K., Rumballe,B., Valerius,M.T., Chiu,H.S.,
            Thiagarajan,R.D., Lesieur,E., Aronow,B.J., Brunskill,E.W.,
            Combes,A.N., Tang,D., Taylor,D., Grimmond,S.M., Potter,S.S.,
            McMahon,A.P. and Little,M.H.
  TITLE     Analysis of early nephron patterning reveals a role for distal RV
            proliferation in fusion to the ureteric tip via a cap
            mesenchyme-derived connecting segment
  JOURNAL   Dev Biol 332 (2), 273-286 (2009)
   PUBMED   19501082
REFERENCE   10 (bases 1 to 1764)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK007878.1.
            
            On Apr 6, 2007 this sequence version replaced NM_026433.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007878.1, BC034841.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1764              AK007878.1         2-1765
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 54.75 cM"
     gene            1..1764
                     /gene="Tmem100"
                     /gene_synonym="1810057C19Rik"
                     /note="transmembrane protein 100"
                     /db_xref="GeneID:67888"
                     /db_xref="MGI:MGI:1915138"
     exon            1..396
                     /gene="Tmem100"
                     /gene_synonym="1810057C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            397..534
                     /gene="Tmem100"
                     /gene_synonym="1810057C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            535..1764
                     /gene="Tmem100"
                     /gene_synonym="1810057C19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             608..1012
                     /gene="Tmem100"
                     /gene_synonym="1810057C19Rik"
                     /codon_start=1
                     /product="transmembrane protein 100"
                     /protein_id="NP_080709.1"
                     /db_xref="CCDS:CCDS25239.1"
                     /db_xref="GeneID:67888"
                     /db_xref="MGI:MGI:1915138"
                     /translation="MTEESTKENLGAPKSPTPVTMEKNPKREVVVTTGPLVSEVQLMA
                     ATGGAELSCYRCIIPFAVVVFITGIVVTAVAYSFNSHGSIISIFGLVLLSSGLFLLAS
                     SALCWKVRQRNKKVKRRESQTALVVNQRCLFA"
ORIGIN      
        1 tctgcagctt cacactacaa aagagtgata tcgaagacta ggttagagaa aaccataaaa
       61 aagaatgctt gcataaggat tttaaacggg ggaaagaaaa caggagagat ttttagtgac
      121 tttttaaata attgggttat gatggattca ctcctgtaat tacagtggat ggtgtgggca
      181 cggaaaaaaa aatagaaaag aaaaggaaaa cgtagagtaa aatacaacag cgagtaagga
      241 atttcctttc accaaattgt ctccggtccc ttaatggtct gtaaatcttg ctgagtactt
      301 tgtgtacggt ccctagcatg gtgatttgca tcccactgtc ggcctcgctg ttggccgccg
      361 cttgctgctg tctcagtcca cttctggctg agaaagaggc aatccctggt ctgtcctttt
      421 accaatgccc agtgggtgac aggctctttc ccagaagttg aacggagcta cgctggcaga
      481 tccctctctc ccaagtcaag tggcctctct ggtaatggac tgcctttctg tgagcttgca
      541 tcctgaccag gctttccaaa tctagcctgt gaagcgagat aagaaaaatc ccacagaaga
      601 aaaaaaaatg accgaagaat ccacaaaaga gaacctggga gctccaaaat ctcccacacc
      661 tgtgacaatg gagaaaaacc ccaagaggga agttgtggtc accacgggac ccttggtcag
      721 cgaggttcag ctgatggccg ccaccggggg tgccgaactc tcctgctacc gctgcatcat
      781 cccctttgcc gtggtggtct tcatcactgg gattgtggtc accgctgtgg cttacagctt
      841 caattcccat ggttccatca tctccatctt cggcctggtc cttctgtcct ccggactgtt
      901 tttactagcc tccagtgcct tgtgctggaa ggtgagacaa aggaacaaga aagtcaagag
      961 acgcgagagt cagaccgctc ttgtggtaaa tcagaggtgc ttgtttgctt aagactgagt
     1021 aagagcaaac gcgaacgctc acccgcccac actgctctaa ctcagtgaac tcattcatag
     1081 gaaaccagcc cggtaccgga tgagctcaac tttcgaatga actaccaaaa tgaaaaatag
     1141 ggcatagaga ggactgaaaa tgaggggtca agacggttcc cccttggtag ggaataactc
     1201 atctttaacg acaaacttaa ccctaagggc tatttctaac acagacagag gaatcagctt
     1261 gcttttcctg ttaaacgttt agggagtgtg ggagatgcac agcattaaat aacagttggt
     1321 tccatttaga aagtacccaa gggaagaatg gacaaataat gagagccctg gcaagtggtg
     1381 ttataaaaac gttccaccaa aagcctacat tggcttggca ttcccacgta cctaagaagt
     1441 tctgttatat atatacatat atattttttc caataagttg attctttgcc cccccctttt
     1501 taaaagaatt ttcactttca gtaacatcac tagaggtact ttattttgaa gaatagacta
     1561 atatttttta tattttaaca atggacaatt gtagatggtt gtaatgatat gtcagaagaa
     1621 aacagaaatg taggtaacac agatgacaca gggacagtta aattaatatt gaaataatcc
     1681 aatctagcac ctttgatggc ttttatacaa aagttcagtg tgcatttcac tcaaaataat
     1741 aaatgctcat ggctgctgaa actt
//
