LOCUS       NM_028876               3871 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus transmembrane p24 trafficking protein 5 (Tmed5),
            transcript variant 1, mRNA.
ACCESSION   NM_028876 NM_028445 XM_910742
VERSION     NM_028876.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3871)
  AUTHORS   Nagae,M., Liebschner,D., Yamada,Y., Morita-Matsumoto,K.,
            Matsugaki,N., Senda,T., Fujita,M., Kinoshita,T. and Yamaguchi,Y.
  TITLE     Crystallographic analysis of murine p24gamma2 Golgi dynamics domain
  JOURNAL   Proteins 85 (4), 764-770 (2017)
   PUBMED   28066915
  REMARK    GeneRIF: Crystallographic analysis of murine p24gamma2 Golgi
            dynamics domain has been reported.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159996.7, AK014490.1, BB764499.1 and BB376243.1.
            
            On Mar 19, 2018 this sequence version replaced NM_028876.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014490.1, AK033463.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AC159996.7         116871-116899
            30-3780             AK014490.1         2-3752
            3781-3811           BB764499.1         463-493
            3812-3871           BB376243.1         259-318
FEATURES             Location/Qualifiers
     source          1..3871
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 52.49 cM"
     gene            1..3871
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /note="transmembrane p24 trafficking protein 5"
                     /db_xref="GeneID:73130"
                     /db_xref="MGI:MGI:1921586"
     exon            1..385
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..886
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; transmembrane emp24 domain-containing protein
                     5; p24 family protein gamma-2; transmembrane emp24 protein
                     transport domain containing 5"
                     /codon_start=1
                     /product="transmembrane emp24 domain-containing protein 5
                     isoform 1 precursor"
                     /protein_id="NP_083152.1"
                     /db_xref="CCDS:CCDS19508.1"
                     /db_xref="GeneID:73130"
                     /db_xref="MGI:MGI:1921586"
                     /translation="MGGRMWLPFPVLLLSALPAALLRGAAGFTPSLDSDFTFTLPAGR
                     KECFYQPMPLKASLEIEYQVLDGGELDIDFHLTSPEGRTLVFEQRKSDGVHTIETEDG
                     DYMFCFDNTFSTISEKVIFFELILDNMGEEVQGQEDWKKYITNTDVLEMKLEDILESI
                     NSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLK
                     SLFEDKRKSRT"
     exon            386..483
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /inference="alignment:Splign:2.1.0"
     exon            484..667
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /inference="alignment:Splign:2.1.0"
     exon            668..3871
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3765..3770
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /note="hexamer: AATAAA"
     polyA_site      3786
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
                     /note="major polyA site"
     polyA_site      3844
                     /gene="Tmed5"
                     /gene_synonym="3110020O18Rik; 4432412D15Rik; p24gamma2"
ORIGIN      
        1 gaaggatgcg aaacccagaa ggcagccgaa aggggacgct ggccccgccc tcgcccggcc
       61 cagtggaagg cagtgcttcc accttccaag agagtgaggc tcgccgctgc ctgaagttcc
      121 ctcagatcgg gatttcaaat cggagacacc agtatcccgc acctccctac acgcgtccag
      181 gcagagatcg acagggatgg gcggcaggat gtggctgcca ttccccgtgc tgctcctgtc
      241 cgctctgccc gcagcgttgc tgcgcggggc ggccggcttc acaccctctt tggacagtga
      301 ttttaccttc acgctgccgg ccggccggaa ggagtgtttc taccagccca tgcccctgaa
      361 ggcatcgttg gagatcgaat accaagtttt agatggagga gaattagata ttgatttcca
      421 ccttacctct ccagagggca gaaccttagt ttttgaacaa agaaaatcag atggtgttca
      481 tactatagag actgaagatg gtgattacat gttctgcttt gataacacat tcagcaccat
      541 ttctgagaag gtaattttct ttgaattgat cctggataat atgggagaag aggttcaagg
      601 ccaagaagac tggaaaaagt atattactaa tacagatgtc ctggagatga agctagaaga
      661 tatcctggaa tccatcaaca gcatcaagtc cagactaagc aaaagtggcc acatacaaac
      721 tctacttaga gcatttgaag ctcgagatcg aaacatacaa gaaagcaact ttgacagagt
      781 caatttctgg tctgtggtta acttgatggt catggtggtg gtgtcagcta ttcaagttta
      841 tacgctgaaa agtctatttg aagataagag gaaaagtaga acttaaaact ccaacacaga
      901 ttatttaaca ttgaaaaaaa gaggtagaaa attctaatac actgttacac agtcaagata
      961 ttagtcatat ttcccataac atttttagaa atgtatgtaa gtgtaagata atgtaaaatt
     1021 tattatgaaa ggaaaatcat tatgtccaga taactttatt gacttgtttt atacttaagt
     1081 atgaaacaag atgtcatgta aaatttagat ttaattgaat gaagccataa taactatttt
     1141 cctaaagtta aaaatctttc ccagatatca tatatgaatt aaatgaatta acaatgttca
     1201 taaacatgcc accagtttgc ttttacctag aattttctct gtatatgtgg caggtacaag
     1261 ttaaagaagt ttccaatacc ttacattaga aatcatttga tggccgggca gtggtggcgc
     1321 acgcctttaa tcccagcact tgggaggcag aggcaggtgg atttctgagt tcgaggccag
     1381 cctggtctac aaagtgagtt ccaggacagc cagggctata cagagaaacc ctgtcttgaa
     1441 aaaacaaaaa taaaaataaa aataaacaaa aaaaaaaaaa aaaagaagaa agaaaagaaa
     1501 aaaagaagaa atcatttgat aattatataa tcatggactg aatagatcag cttttctcta
     1561 ctaaatctct ccaaaaaaag taaatacaag cataccactg aaaaaatact cctatcattt
     1621 ttacaaccaa atataatgtg aaatattatc cacaagtatt agtttttata tacttagtct
     1681 atacttccaa aacctaacat ttttataatt aaaactggaa agggattctt tctttataaa
     1741 aattagacag tgtctttgtc tttgatataa ggtatataaa gggtagttga tgtttgtgac
     1801 tgagatgcat tctgtctaga cgttagctaa gattaaatta gagataagat gaacttattt
     1861 ttatattacg catcagcagt gttaagttgg tattgataat gcattatcac aagcaggtgt
     1921 gagggacata ctaatgaaaa gatctgacat cagtgtaaat aaacagctcc tttctaaatt
     1981 ctcaaaacca tcagaaacat gaaggaaaaa aatgagataa atatgacacc agatccaaca
     2041 agtttaccta gagaagtgta acatctagaa tcaggtgggc tcttcttgct aacccaatta
     2101 taataaagat cagatcaaag gagggtaatc taaaattccc cagaagaaat tgtatttgtc
     2161 atagcttttt attctaatta ctgtttttat tataaatgtt cagatagatt ttgtgaaatg
     2221 tatattccta ccataagact tagcactagg tatgcatatt tattacagtt tttattatag
     2281 ctctcacaaa attacctctg gtcatttatt ggcttagaac aatcccaaat tataaacacc
     2341 taatgtagaa ataaaagcca atgtatacaa aaacattctg cctttctggt ttatcagtct
     2401 gtagtacaat tttattcaag tactagtgat ttaggtttat catgaaacag aatttaagtt
     2461 acactcactt gtagtgttta taataaatgt attgtcaagt agagatagtc aatagtcaga
     2521 tctgggtatt gaacccatat aaacatacac atattttttt ttgctggaat tcttattacg
     2581 tattaatgat cttgcactac cctgctacct cacacacaaa attatgatac ccagagaaat
     2641 actgatttca tttacaattt atactcagaa tagttcaaaa atatagtttc ctctttctca
     2701 ggcccttggg aggaaactag aaatttattt ttccctatcc agaggctttt caaaatgtga
     2761 gataaatact atatgtgatc aataactgac caagaaaaat gccctaggct tctaaccaag
     2821 ctcctacaat agatgcagaa aagaggccaa tgagatcgtt gcctaaaaaa actctcttcc
     2881 ctactttaag tgcaagagaa gcaagctcta gacagctatc ctaactgata aagcagagtc
     2941 cactgcgtct cttctgaaag actgtgacta agaatcctac ctcttagata cagctgatac
     3001 tgtactgtgt tcttaactgc ttacttaaca ctgtatctgt tacatcatct tgtatgtatg
     3061 gaatttgtgc cactgacttt ttgaattctt actcagttac tcactgccat ttaaaatggt
     3121 catagtagct ttgctggaaa atcgaataac ttaggaatgt taaaagattt tatttttata
     3181 gacaaaagta aaaagatact aagaaccatg ttgcctgtat taatcataaa gaagtaaaat
     3241 tgtaagcaaa aaccaaaatg tttattttta aatgtgtatt ttctgcttca tagaagtttt
     3301 ttgaccttac tgtcttaatt atactaaaat caagtaagcc atcacttgct ctgatttttg
     3361 tcttgttaat tgtataaatt actacagtag cttaacaagt ttagagatca ttgttcttag
     3421 ttgcagttgg actgtgtgct cttttatatg aatgtcaata aacagagact aagtaagtgt
     3481 aagaagacat tgttgaaaca taaatcaaaa tatacttagg aatatttaca attaaacatg
     3541 atgttttaaa cttagtaaaa aacaaaagca aaaacaaaca agtacctgta attttgtacc
     3601 tacagtgaaa attctttatc tgaaatttta aaatacattg atatagcatg taattttttt
     3661 tcttctggag tataatacaa tgtggctcat atggcactat atactatatt tgtgaacttt
     3721 tatcttaaat gaacaacaga ctatgtactg agctccatac aactaataaa aggtactatc
     3781 aaggaagtct taccaaccta tcataattgt tacctactcc ttaaagcttc tttaaaaatt
     3841 tcaatcttaa gtaaatttgt ttttctttca c
//
