LOCUS       NM_010744               1535 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus transmembrane p24 trafficking protein 1 (Tmed1),
            transcript variant 1, mRNA.
ACCESSION   NM_010744
VERSION     NM_010744.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1535)
  AUTHORS   Gayle,M.A., Slack,J.L., Bonnert,T.P., Renshaw,B.R., Sonoda,G.,
            Taguchi,T., Testa,J.R., Dower,S.K. and Sims,J.E.
  TITLE     Cloning of a putative ligand for the T1/ST2 receptor
  JOURNAL   J Biol Chem 271 (10), 5784-5789 (1996)
   PUBMED   8621446
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC138498.1 and AK133513.1.
            
            On May 12, 2016 this sequence version replaced NM_010744.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133513.1, U41805.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                BC138498.1         1-48
            49-1535             AK133513.1         1-1487
FEATURES             Location/Qualifiers
     source          1..1535
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.81 cM"
     gene            1..1535
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /note="transmembrane p24 trafficking protein 1"
                     /db_xref="GeneID:17083"
                     /db_xref="MGI:MGI:106201"
     exon            1..241
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..742
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; interleukin 1 receptor-like 1 ligand;
                     transmembrane emp24 domain containing 1; transmembrane
                     emp24 domain-containing protein 1; p24gamma1; p24 family
                     protein gamma-1; putative T1/ST2 receptor-binding protein;
                     lymphocyte antigen 84 ligand"
                     /codon_start=1
                     /product="transmembrane emp24 domain-containing protein 1
                     isoform 1 precursor"
                     /protein_id="NP_034874.2"
                     /db_xref="CCDS:CCDS22904.1"
                     /db_xref="GeneID:17083"
                     /db_xref="MGI:MGI:106201"
                     /translation="MMAAGAAVALALWLLLPAVGVGEAGPPPIQDGEFTFLLPAGRKQ
                     CFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGD
                     YRLCFDNSFSTISEKLVFFELIFDSFQDEEEVEGWAEAVEPEEMLDVKMEDIKESIET
                     MRTRLERSIQMLTLLRAFEARDRNLQEDNLERVNFWSAANVAVLLLVAVLQVCTLKRF
                     FHDKRPVPT"
     exon            242..339
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /inference="alignment:Splign:2.1.0"
     exon            340..523
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /inference="alignment:Splign:2.1.0"
     exon            524..1535
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1337..1342
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /note="hexamer: AATAAA"
     polyA_site      1360
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /note="major polyA site"
     regulatory      1513..1518
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
                     /note="hexamer: CATAAA"
     polyA_site      1533
                     /gene="Tmed1"
                     /gene_synonym="Il1rl1l; Ly84l; St2l"
ORIGIN      
        1 gaggtgggca ggacaaatcc ttaaagggtc cacgccccgt gagtagaggg tgacccggat
       61 gatggcggcc ggcgcggccg tagcactggc cctgtggcta ctcctgccag cagtaggagt
      121 gggagaggca gggccgccgc ctatccagga cggcgagttc acatttctgc ttcccgccgg
      181 gagaaagcag tgtttctatc agtccgcacc ggccaatgct agtcttgaga ccgagtacca
      241 ggtgatcgga ggtgctgggc tggacgtgga cttcaccttg gagagccctc agggtgtgct
      301 gttggtcagt gagtctcgaa aggctgatgg ggtacacacg gtggagccta ctgaggccgg
      361 agactacagg ctgtgctttg acaactcctt cagcaccatc tcagaaaagc ttgtgttctt
      421 tgagctcatc tttgacagct tccaagatga ggaggaggta gaaggttggg cggaggctgt
      481 ggagccagaa gagatgcttg atgtcaaaat ggaagacatc aaggaatcca tagagaccat
      541 gaggacccgg ctggaacgga gcatccagat gctcactctg ctccgagcct ttgaggctcg
      601 tgatcgaaat cttcaagaag acaacctgga gcgggtcaac ttctggtcag ctgccaatgt
      661 ggctgtgttg ctgctggtgg ctgtcctgca agtctgcaca ctcaagcgct tcttccatga
      721 caagcgccct gtacccacgt agcccctgcc acagaggatg agggcagcgg gtgtgtgact
      781 tgctggacac ctcccagact cagatgagac actacatagt tgggtcctta gcagtggccc
      841 catgtgtctc ccttcctcag tgaccaggga gtgccaatgg ctcacagacc cctcggaagg
      901 gggagggctc agcgactgtg cctgttcctt ggagggtgga agtgctgggc gcagcagtgt
      961 ggggacactg ctcttggatg ccctggcttt ctcctgaaat cgtgccttag cttcagtctt
     1021 gcagctatca ggatggggtg aagctgtggt gctgcccccc accctccaac tagacacccc
     1081 aactgcaatg tctctgctct cctcctgggg taagcctact tcactagggt ctgggaagga
     1141 gacacatctg cagagttctt gccaggacag tcacttttat ttgaaaggaa ggagccctgg
     1201 ccccttggcc cagaggggag ccagctagta ggtggtttgg gagaggcccc ttccttctct
     1261 ctgggtgcag ggcctcagag aaggctggcc catgagcctc aaggaacaga gggcatttgt
     1321 cctgggcact ggagtcaata aattatggtc agaaagttaa tagtgcctgg tgactgggct
     1381 tagggatgtc agcttgggac agacctagcc tcaagccagg gcagccagga aggggggaca
     1441 ctcccacgaa gctcagaaga aaggtcgggc aggagccaat ggaggtggtc gcctggcacg
     1501 aaagaaaaag accataaacc atggctgaat gaact
//
