LOCUS       NM_001305423            3531 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus transmembrane and coiled-coil domains 4 (Tmco4),
            transcript variant 1, mRNA.
ACCESSION   NM_001305423
VERSION     NM_001305423.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3531)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK148086.1, AL805923.6, AK014571.1 and BB030219.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014571.1, SRR13422600.1746386.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849378, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               AK148086.1         1-125
            126-126             AL805923.6         29598-29598
            127-258             AK148086.1         127-258
            259-264             AL805923.6         29731-29736
            265-512             AK148086.1         267-514
            513-515             AL805923.6         29985-29987
            516-609             AK148086.1         517-610
            610-2363            AK014571.1         2-1755
            2364-2364           AL805923.6         111100-111100
            2365-3524           AK014571.1         1757-2916
            3525-3531           BB030219.1         299-305
FEATURES             Location/Qualifiers
     source          1..3531
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 70.57 cM"
     gene            1..3531
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /note="transmembrane and coiled-coil domains 4"
                     /db_xref="GeneID:77056"
                     /db_xref="MGI:MGI:1924306"
     exon            1..707
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            708..852
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            853..971
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1150
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             981..2876
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /note="novel DUF726 domain containing protein"
                     /codon_start=1
                     /product="transmembrane and coiled-coil domain-containing
                     protein 4"
                     /protein_id="NP_001292352.1"
                     /db_xref="CCDS:CCDS18837.1"
                     /db_xref="GeneID:77056"
                     /db_xref="MGI:MGI:1924306"
                     /translation="MATWNRPHPRQPVAPEPAAEDDSQQPLGRELSEANRFAYAALCG
                     FSLSQLFPEPEQSSFCTEFVTGLVKWLHLSESVLPTIMAFASGLGGEGADIFAQTLLQ
                     DPILRDNPSAVSQDLLSFSLKNGHYDARARVLVCHVTSLLQVPMEELDILEEVFLESL
                     KDAKEEESETAEASRKRKEKRRKWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAAT
                     IIGSAGAAALGSVAGIAVMTSLFGAAGAGLTGYKMKKRVGAIEEFMFLPLTEGRQLHI
                     TIAITGWLGSGRYRTFNAPWMALARSQEQYCLAWEAKYLMELGNALETILSGLANMVA
                     QEALKYTVLSGIVAALTWPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGR
                     RPVTLIGFSLGARVIYFCLQEMAQEQDCQGIIEDVVLLGAPVEGDPKHWEPFRNVVSG
                     RIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRMENVDLTSVVNGHLDYAKQM
                     DAILKVVGIRTKPGWREKGLPLAPGSLPQEEPLQTAIVSTDEIILQDGQSQGPASEDS
                     LKTTIPSSASQAQMPAGLNQSTEDSLSTAAAPAEGHLICSHGVGPNPLGCPDCTHGTQ
                     ESCTELD"
     exon            1151..1325
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1353
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1486
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1584
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1728
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1848
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..2013
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2150
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2235
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2236..2353
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..2471
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..3531
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3508..3513
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3527
                     /gene="Tmco4"
                     /gene_synonym="4632413C14Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggctccctgc tggaatgccg cacgtctcat ctgtccgctc gagaactttt tccatttcca
       61 actccagcct atcttctcca ggggaaagag caacgacgtc agaggtcatg gtgactcaga
      121 ttccagccct gaccaggatg gccacctact tcctcacctg tagattaggt gtgatgaaat
      181 ttcacaggtt gcctgggcaa ccaagagccg gctcccaaat gaggagagcg gaggatgagg
      241 catgggagac aaccccccct tccattcttg gggtctttaa gttctagtgt gggataccca
      301 gattataaat tggcaaacag gaaaacaatc aacttcagtg ttaaatacta cgattaaaat
      361 atgggcccga aggcctggtg tgctaatcca taaccttgct ggcacgtagt aggtgctcag
      421 caaatacttg ttcaaagact agagctgagt gggtggctag tctaacagga atggaacccc
      481 aaaacggagg cccgtgggac ggaagagcca cgggtgcaac gactggcgag cattagagaa
      541 agtgaaagaa cgatcagaag gcgtgggtgt tgcaaatttc accgagcagt gtgcacagga
      601 gggggaggca ccttctggga caggctcttt tcaagtgtgg cggcaaaatt tggaagcttc
      661 cccttcaagt gtctgctcga actcccctca tgccagccca gcccctggtt ccacaccctc
      721 tggacccatg gctggttttt ctggtttagt ctgtagagca atttgcatat ttccttgaag
      781 aactctctga agctttacag cctgtccttg gactcacaga gagggacgcc cacgttggtt
      841 ctccagaatt ggaatgaaag ccccttcatt cttcagtgtt tgatgcatgc cgtagtctaa
      901 gccagtggaa gctcggggcg taagcaagga ctccacctgc cctgagactt acattccttg
      961 tgtgcacaca ggggctggga atggccacat ggaacaggcc acacccaagg cagcctgtgg
     1021 caccagagcc agctgcagaa gacgattccc agcagcccct gggccgggag ctctcggagg
     1081 ccaatcgctt cgcctatgcc gccctgtgtg gcttctcgtt gtcacagctg tttccagaac
     1141 ctgaacaaag ctccttctgc acagaatttg tgacgggcct ggtgaaatgg ctgcatctgt
     1201 ctgaaagtgt cctcccaacc ataatggcct ttgccagtgg cctgggaggc gaaggagccg
     1261 acatctttgc tcagacttta ttgcaggacc ccattctgag agacaaccca tcagcagtca
     1321 gtcaggacct cctgagcttc tcactcaaga atggacacta tgatgcccgg gccagagtcc
     1381 tcgtttgtca tgtgacctcc ctgctccagg tgcccatgga ggagcttgac attctggaag
     1441 aggtgttcct ggagagcctg aaggacgcca aagaggagga gtctgagacc gcagaggcat
     1501 cccggaagag gaaagaaaaa cggaggaagt ggaaacgcta tcttctgata ggcctggcca
     1561 cagttggagg cgggacagtg attggtgtga ctggggggct agctgcccca cttgtcgctg
     1621 caggagccgc aaccatcata ggcagtgccg gggcagccgc gttgggctca gtggctggca
     1681 tcgctgttat gacttcactg tttggtgcag ccggagctgg cctgacagga tacaagatga
     1741 agaagcgagt cggggccatt gaggagttca tgttcctgcc tttgacggaa ggccggcagc
     1801 tacatatcac cattgccatc actggctggc tcgggtccgg cagataccgc acatttaatg
     1861 ccccatggat ggccctagcc cgcagccagg agcagtactg cctggcctgg gaggccaagt
     1921 acctgatgga gttgggcaat gccctggaga ccatcctcag tggcctcgct aacatggtag
     1981 cacaggaggc tctcaagtac acagtgctct ctggtatcgt ggctgctcta acctggccag
     2041 cctcactcct cagcgtcgcc aatgtcatcg acaacccctg gggcgtgtgc ctccaccgat
     2101 cggcagaagt tggcaagcac ctggcgcaca tccttctctc acggcaacag ggccggagac
     2161 ctgtcacctt gattggattc agcctgggag ccagagtcat ctacttttgt ctgcaagaaa
     2221 tggctcagga gcaagattgc caagggatca tcgaggatgt ggtccttctg ggcgcaccag
     2281 tagaagggga ccccaagcac tgggaaccat tccggaatgt ggtgtctggg agaatcatca
     2341 atggctactg caggggagac tggctgctga gcttcgtgta ccgcacatct tccgtgcagc
     2401 tccgcgtcgc cggcctccag cctgtgctgc tgcaggaccg gaggatggag aatgtggacc
     2461 tgacctccgt ggtcaatggc cacttggact acgccaagca aatggatgcc atcctgaagg
     2521 ttgtgggcat ccgcaccaag cctggctgga gagagaaggg actcccactg gcccctggca
     2581 gcttgcccca agaagagcct ctccagacag ccatagtctc tacagatgag ataatcctcc
     2641 aggatggaca aagccaggga cctgcctcag aagacagtct caaaaccacc ataccttcca
     2701 gtgccagcca agcccagatg ccagcagggc tgaaccagtc cacagaggac tcgctctcta
     2761 ctgctgctgc tccggcagag ggacacctga tctgcagcca tggtgtgggt cccaacccac
     2821 tgggctgccc tgactgcacc catgggaccc aggagtcctg tacagaactg gactgaccca
     2881 gcaggcatct ggactacctc tccagacttc tgtatgcaac tttctctaac ccttgctgac
     2941 ttcccagaga gctctagggg tggggaattt ccacaagtgc cttttttaaa cagataggag
     3001 ctagaatgga gaggtgaggg agaaagcact ggctttagga ggcaggacta gcagtatgac
     3061 ctgccaggtc aacccagcgc taaaccagtg taggctcctg ccctgcaggt cccatccaaa
     3121 ggcccaaacg tttctgtggg actagaggtc cccgtgctcc cttttctcca acctcagtgg
     3181 acccaagtgt cttccagatc ttccatcaac tctcccaggc tgcccactga tcccaggctc
     3241 caccagcgag cgttttcagg tgccaatgag acactttgct cccctgccct tggaaggagc
     3301 agctctgtcc agtacattta tgcaggctgg gtgcactgga caacggcagg cgtaacaggc
     3361 atcgatgtga tgtatgtggc agcccaccct gagcttgtga aacatgtgac cctggataga
     3421 attgtagcaa gaggaataaa ggcagaagtc acagtcaggc tctcaaggac tgggccttgg
     3481 taagcatgga ttacatgagg ggggaccaat aaacactgat tatcacaccc t
//
