LOCUS       NM_133847               3895 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus transmembrane 9 superfamily member 4 (Tm9sf4), mRNA.
ACCESSION   NM_133847
VERSION     NM_133847.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3895)
  AUTHORS   Zhao,R., Liao,W., Tan,D., Huang,H., Hu,C. and Chen,M.
  TITLE     Comparative analysis of the expression patterns of TM9SF family
            members in mice
  JOURNAL   Gene Expr Patterns 52, 119366 (2024)
   PUBMED   38719197
REFERENCE   2  (bases 1 to 3895)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3895)
  AUTHORS   Xie,M., Mak,J.W.Y., Yu,H., Cheng,C.T.Y., Chan,H.C.H., Chan,T.T.,
            Lau,L.H.S., Wong,M.T.L., Ko,W.H., Jiang,L. and Yao,X.
  TITLE     TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in
            Inflammatory Bowel Disease
  JOURNAL   Cell Mol Gastroenterol Hepatol 14 (2), 245-270 (2022)
   PUBMED   35398597
REFERENCE   4  (bases 1 to 3895)
  AUTHORS   Yu,L., Xie,M., Zhang,F., Wan,C. and Yao,X.
  TITLE     TM9SF4 is a novel regulator in lineage commitment of bone marrow
            mesenchymal stem cells to either osteoblasts or adipocytes
  JOURNAL   Stem Cell Res Ther 12 (1), 573 (2021)
   PUBMED   34774100
  REMARK    GeneRIF: TM9SF4 is a novel regulator in lineage commitment of bone
            marrow mesenchymal stem cells to either osteoblasts or adipocytes.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3895)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3895)
  AUTHORS   Sun,L., Meng,Z., Zhu,Y., Lu,J., Li,Z., Zhao,Q., Huang,Y., Jiang,L.
            and Yao,X.
  TITLE     TM9SF4 is a novel factor promoting autophagic flux under amino acid
            starvation
  JOURNAL   Cell Death Differ 25 (2), 368-379 (2018)
   PUBMED   29125601
REFERENCE   7  (bases 1 to 3895)
  AUTHORS   Liakath-Ali,K., Vancollie,V.E., Heath,E., Smedley,D.P., Estabel,J.,
            Sunter,D., Ditommaso,T., White,J.K., Ramirez-Solis,R., Smyth,I.,
            Steel,K.P. and Watt,F.M.
  TITLE     Novel skin phenotypes revealed by a genome-wide mouse reverse
            genetic screen
  JOURNAL   Nat Commun 5, 3540 (2014)
   PUBMED   24721909
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 3895)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
REFERENCE   9  (bases 1 to 3895)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 3895)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL807380.6.
            
            On Nov 17, 2006 this sequence version replaced NM_133847.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083541.1, AK088012.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-271               AL807380.6         16097-16367
            272-385             AL807380.6         33685-33798
            386-485             AL807380.6         37184-37283
            486-654             AL807380.6         42059-42227
            655-787             AL807380.6         42327-42459
            788-911             AL807380.6         43750-43873
            912-1030            AL807380.6         45627-45745
            1031-1142           AL807380.6         45847-45958
            1143-1213           AL807380.6         46726-46796
            1214-1346           AL807380.6         49073-49205
            1347-1428           AL807380.6         50107-50188
            1429-1504           AL807380.6         50286-50361
            1505-1588           AL807380.6         53146-53229
            1589-1764           AL807380.6         55439-55614
            1765-1828           AL807380.6         57134-57197
            1829-1948           AL807380.6         58578-58697
            1949-2038           AL807380.6         59331-59420
            2039-3895           AL807380.6         63403-65259
FEATURES             Location/Qualifiers
     source          1..3895
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 75.41 cM"
     gene            1..3895
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /note="transmembrane 9 superfamily member 4"
                     /db_xref="GeneID:99237"
                     /db_xref="MGI:MGI:2139220"
     exon            1..271
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..2188
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /note="transmembrane 9 superfamily protein member 4"
                     /codon_start=1
                     /product="transmembrane 9 superfamily member 4 precursor"
                     /protein_id="NP_598608.2"
                     /db_xref="CCDS:CCDS16906.1"
                     /db_xref="GeneID:99237"
                     /db_xref="MGI:MGI:2139220"
                     /translation="MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKA
                     VKLTSSRTQLPYEYYSLPFCQPIKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEV
                     LCNQSNKPITLTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDKKKEK
                     DVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLE
                     DLKTGEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSD
                     VQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGD
                     VFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGV
                     FGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTM
                     VALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAG
                     ILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDY
                     RWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTI
                     GFYAAYMFVRKIYAAVKID"
     exon            272..385
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            386..485
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            486..654
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            655..787
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            788..911
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1030
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1142
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1213
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1346
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1428
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1504
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1588
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1764
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1828
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..1948
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            1949..2038
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..3895
                     /gene="Tm9sf4"
                     /gene_synonym="B930079E06; mKIAA0255"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaaaaggag taggcggagg agcgggtctg ccagaagtca atatggctcc aatagttaca
       61 ccgtacgttc tcttcaccta gtcagagacc tcactgccaa ggccaatctg ccaaggagaa
      121 attaagcttc ttttacctcc tcactactgc gactacagaa gaatctgaag ccaggagtcc
      181 ccttagtgga gctacactcc gtaaccacag aagcaccact tccgctgacg tcatcacgcc
      241 gacacgtgga tccaagatgg cggcggcgat gatttggtgg ccaaggttcc tgctgcttct
      301 ctgtctaaca tgtaaaggaa gcaccttcta tgtccctgga gtcgcgccaa tcaatttcca
      361 ccaaaacgac ccagtagaga tcaaggctgt gaagcttacc agctctcgga cccagcttcc
      421 ttacgagtac tactcattgc ccttctgcca gcccatcaag ataacctaca aggcagagaa
      481 cctgggagag gtgctgagag gggaccggat tgtcaacacc cctttccagg ttctcatgaa
      541 cagtgagaag aagtgtgaag ttctatgcaa ccaatctaac aagccaataa ccttgacagt
      601 ggaacagagc cggctggtgg ccgagcgaat cacagaagaa tactacgttc acctcattgc
      661 tgacaacctg cctgtggcca cccggctgga gctctactcc agcaaccgag acagtgatga
      721 caagaagaaa gaaaaagatg tgcagtttga acatggctac cgacttggct tcacggatgt
      781 caacaagatc tacctgcaca atcacctctc attcatcctt tattaccacc gggaggacat
      841 ggaagaggac caggagcaca cataccgtgt cgtccgcttc gaggtgattc cccagagcat
      901 caggctggag gacctcaaaa caggcgagaa gagttcatgt accctacccg agggtgccaa
      961 ctccttaccc caagaaattg accccactaa ggagaatcag ctgtacttca cctactctgt
     1021 gcactgggag gaaagtgaca tcaaatgggc ctctcgatgg gacacttacc taaccatgag
     1081 tgatgtgcag atccactggt tttccatcat taactctgtc gtggtagtct tcttcctgtc
     1141 aggcatcctc agcatgatta tcatccggac cctgcggaag gacatcgcca actacaacaa
     1201 ggaggatgac attgaagaca ccatggagga gtctgggtgg aagcttgtgc atggtgatgt
     1261 cttcaggcca ccccaatatc ccatgatcct cagctctctg ctgggctcag gcattcagct
     1321 cttctgcatg atcctgattg tcatcttcgt ggccatgctt gggatgctgt cgccgtccag
     1381 ccggggagct ctcatgacca ctgcctgctt cctcttcatg ttcatggggg tatttggtgg
     1441 attttctgct ggccgtctct accgaactct aaaaggccat aggtggaaga aaggagcctt
     1501 ctgtacagcg acactgtatc ctggtgtggt tttcggcatc tgctttgtgt tgaattgctt
     1561 catctgggga aagcactcat caggagcagt accgtttccc accatggtgg cgttgctgtg
     1621 tatgtggttc gggatctccc tgccccttgt ctacttgggc tactatttcg gcttccgcaa
     1681 gcagccatat gacaaccctg tgcgcacaaa ccagattccc cggcagatcc ctgaacaacg
     1741 gtggtacatg aaccgatttg tgggcatcct catggctggg atcctgccct ttggtgccat
     1801 gttcattgag ctgttcttca tcttcagtgc aatctgggag aaccagttct attacctctt
     1861 cggtttcctg ttcctcgttt tcatcatcct ggtggtgtcc tgctcacaaa tcagcatagt
     1921 catggtgtac ttccagctgt gtgcagagga ttaccgctgg tggtggagga atttccttgt
     1981 ctcaggggga tctgcattct acgtcctggt ctatgccatc ttttattttg ttaacaagct
     2041 ggacatcgtg gagttcatcc cttccctcct ctactttggc tacaccaccc tcatggtcct
     2101 gtccttctgg ctgctcacag ggaccatcgg cttctacgca gcctacatgt ttgtccgcaa
     2161 gatatatgct gctgtgaaga tagactgagt gggtggacca acgctgggcc cactggatcc
     2221 tcgacaggaa gccaccctgc gtggggactg caggcacaca aaataaaata actcgtgctc
     2281 atttggaatg taactcctgg cacagtgttc ctagaccccc aggctgcatg ggggacagga
     2341 gggcctgtag ataacccttc catttccttc atctcatcca gtctgtaggg atacattttt
     2401 ctgtggttgg ttttcttcag ctaagagtcg ctgtcagcag gagctttctg acctgttaat
     2461 tcaggttctt tttggtttag gttgggtttt ttgttgttgt ttttcggttt tggggttttc
     2521 tttcttcttc ttcttctttt tttttttttt tcaaaaaaaa aaaaatgcaa atccgggatg
     2581 gataaatgta gggttttggt cactgtcccc atcggctcct cagagttgtt ggccacccta
     2641 ccactaactg gaagaggaaa cgctggggct gcagtgaggg ctccaagctt ctcagtgcca
     2701 accacgccct gccagcccct cctcccattc tcttccccag cctgccctct gccgccccga
     2761 acagtcaggt ctttggtcat cgttttaact gggaacactt ggtcactaca aggacatgtc
     2821 ctggttccct gggacagcag gatcccctcc tcaaagcagc cagagtttac tgaacaccaa
     2881 ggaagaagtg agacctcagt gactgttctc gtgccaagaa gccctgggcc agggccaggt
     2941 gtttccagag ccaagtgccc atgtgtgtat gggaagaggt ggctaaagcc actagactag
     3001 ggtgctcacc cctcaagatt gattccctgt ctttccctct ggggcaccgc actttgtaaa
     3061 gggtgatggt ggaccccttc ccttactttc aggtctggag tcttcagatc tcttccttga
     3121 ggcggccagg gagaggaagt ctcgctctct ctcctcacag cccttggccc cagcatttat
     3181 tcttgggtcc tttagccaaa cccattccct cttcctccca tgcaagttct tttgggaaca
     3241 cccagaaaac ttctctgaga agaaaaatgg aaggtaagtt gagttgctcc tttcccagtt
     3301 cctaggaata ggcaagaagc cagtctcccc aggttggaag aggatcatgg gcctggccta
     3361 gctcctccgc cctggcctag cccagcaaac cctgggcgag tcacagagtt tgctcttaag
     3421 tagcaagaga ccaaactcac cttgggtgta ggggtcagta gcagccactc gcccttgctc
     3481 cagtcctttg ggagcctgtc aggagacaaa gctcaggatg ctgcttgtgc taggaacaca
     3541 ccctgccctc actgccccac ctcctggggc cccaccgcca tcgtcagtca aatcagtgca
     3601 cctctcaatc tgcctcgcag tgacttcgca gcactgagtg gcatccacca ggaatcaggc
     3661 tggagaaatg ggagcccaga gagtggagag tgattgggag ttacttgttc attcaaatct
     3721 tgcacccccc cccccaaggt tctcattgtt ggagagggtg ggggaaaggt tcaaacattg
     3781 tcaatttttc tgacttttta aatcatcatc attattttta attaaaaaaa aatgcctgta
     3841 tgcctttttc tggtccaatt gtaaataaaa tgccattgtc ctgttgtctc aactc
//
