LOCUS       NM_027194               1298 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus TM2 domain containing 2 (Tm2d2), mRNA.
ACCESSION   NM_027194
VERSION     NM_027194.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY018367.1, AK045768.1 and CO044843.1.
            
            On May 1, 2009 this sequence version replaced NM_027194.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026789.1, AK045768.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY018367.1         1-42
            43-1279             AK045768.1         2-1238
            1280-1298           CO044843.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 13.7 cM"
     gene            1..1298
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /note="TM2 domain containing 2"
                     /db_xref="GeneID:69742"
                     /db_xref="MGI:MGI:1916992"
     exon            1..382
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..800
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /note="BBP-like protein 1; TM2 domain-containing protein
                     2"
                     /codon_start=1
                     /product="TM2 domain-containing protein 2 precursor"
                     /protein_id="NP_081470.2"
                     /db_xref="CCDS:CCDS22197.1"
                     /db_xref="GeneID:69742"
                     /db_xref="MGI:MGI:1916992"
                     /translation="MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSFNATAELDL
                     TPSGAAHLEGPAASSWEYSDPNSPVILCSYLPDEFVDCDAPVDHVGNATASQELGYGC
                     LKFGGQAYSDVQHTAVQCRALEGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLG
                     CFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY"
     exon            383..470
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /inference="alignment:Splign:2.1.0"
     exon            471..586
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /inference="alignment:Splign:2.1.0"
     exon            587..1281
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1263..1268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /note="hexamer: AATAAA"
     polyA_site      1281
                     /gene="Tm2d2"
                     /gene_synonym="2410018G23Rik; Blp1"
                     /note="major polyA site"
ORIGIN      
        1 gtagtggcag gcggagcgtc gagctgcgca cgggttggct gtggaacgga gggttgcgta
       61 cccgacgtag agagaggcct gacagcgccg ggctccggtg ggccgtggcg gcctggcttt
      121 gtttttaggc caggtctcta ggaccggccc ccgggaagat ggtgctgggc ggctgccctg
      181 tgagttacct attgctgtgc ggccaggcgg ccctgctatt ggggaacctg ctgctgctgc
      241 actgtgtttc tcggagccac tcgtttaatg ctacggccga actggatctc acaccctcgg
      301 gcgccgctca cctcgagggt cccgcggcct caagctggga atacagcgac cccaactcgc
      361 cagtcatcct ttgctcttac ctacccgacg agttcgtaga ctgtgatgcc ccagtggatc
      421 acgttggaaa tgcaactgcc tcccaggagc ttggttatgg ttgtctcaag tttgggggtc
      481 aggcgtacag tgatgtgcaa cacactgcag tccagtgcag agccctggag ggaattgagt
      541 gtgccagccc caggaccttc ctacgagaaa ataagccttg tataaagtac actggacact
      601 acttcataac cacgcttctc tactccttct tcctgggatg cttcggagtc gaccgcttct
      661 gcctgggcca cactggaaca gcagttggga agctgctaac acttggagga ctggggatct
      721 ggtggttcgt tgatcttatt ctgctcatca ctggggggct gatgcctagt gatggcagca
      781 actggtgcac tgtctactaa gccctgctgc tgtcctgcgc cagcaaggaa agccagtgct
      841 tgcctgccaa gataattact acaagctctg aactctcctc tgagcatcac catcttctct
      901 tggaggaagg accgaccaag tttttcaccc caaatcttaa gcttgcaaac tagagtgaca
      961 agcagtattg tggagtcccg tcgtaccctt cctcacatac acaatctcaa agagcaaagc
     1021 tggtgacttc tctccagaga tcatcgtcag tgacgtttct gtgtggctgg ctcttcagcc
     1081 gttggaggca gggggaccca ccaggataaa ccaagtgagt gtttatccac tcacagcctt
     1141 tcgtgaccct acatttccat gcacaggtca gaagctgcac caatgagaag tcttcaggcg
     1201 atgtagaaat gactgtggat tctaatacac accgaaattc tgactgagaa tttaaattgc
     1261 agaataaagt tttaaaacct aaaaaaaaaa aaaaaaaa
//
