LOCUS       NM_053157               1080 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus TM2 domain containing 1 (Tm2d1), mRNA.
ACCESSION   NM_053157 XM_914833
VERSION     NM_053157.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1080)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 1080)
  AUTHORS   Kajkowski,E.M., Lo,C.F., Ning,X., Walker,S., Sofia,H.J., Wang,W.,
            Edris,W., Chanda,P., Wagner,E., Vile,S., Ryan,K.,
            McHendry-Rinde,B., Smith,S.C., Wood,A., Rhodes,K.J., Kennedy,J.D.,
            Bard,J., Jacobsen,J.S. and Ozenberger,B.A.
  TITLE     beta -Amyloid peptide-induced apoptosis regulated by a novel
            protein containing a g protein activation module
  JOURNAL   J Biol Chem 276 (22), 18748-18756 (2001)
   PUBMED   11278849
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089492.1.
            
            On or before Dec 7, 2005 this sequence version replaced
            XM_914833.1, NM_053157.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089492.1, CF585274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 45.6 cM"
     gene            1..1080
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /note="TM2 domain containing 1"
                     /db_xref="GeneID:94043"
                     /db_xref="MGI:MGI:2137022"
     exon            1..196
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..656
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /note="beta-amyloid binding protein; TM2 domain-containing
                     protein 1; mBBP; amyloid-beta-binding protein"
                     /codon_start=1
                     /product="TM2 domain-containing protein 1 precursor"
                     /protein_id="NP_444387.1"
                     /db_xref="CCDS:CCDS18374.1"
                     /db_xref="GeneID:94043"
                     /db_xref="MGI:MGI:2137022"
                     /translation="MAAAWPAGRASPAAGPPGLLRTLWLVTVAAGHCGAAASGAVGGE
                     ETPKCEDLRVGQYICKEPKINDATQEPVNCTNYTAHVQCFPAPKITCKDLSGNETHFT
                     GSEVGFLKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGI
                     GSLIDFILISMQIVGPSDGSSYIIDYYGTRLTRLSITNETFRKTQLYP"
     exon            197..270
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            271..379
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            380..471
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            472..545
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            546..675
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            676..986
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      964..969
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /note="hexamer: AATAAA"
     polyA_site      986
                     /gene="Tm2d1"
                     /gene_synonym="2310026L18Rik; Bbp"
                     /note="major polyA site"
ORIGIN      
        1 accggaagcg cgaggacgcg gtgcccaaca tggcggccgc ctggcccgcg ggtcgggctt
       61 ccccagcggc ggggcctccg ggccttctcc gcaccctgtg gctcgtgacg gtcgccgcgg
      121 gacactgtgg ggctgctgcc tctggcgctg tcgggggcga ggagacaccc aagtgtgagg
      181 acctcagggt gggacaatat atttgtaaag aaccaaaaat aaatgatgct acgcaagaac
      241 cagttaattg tacaaactac acagctcatg ttcaatgttt tccagcaccc aaaataactt
      301 gtaaggattt gagtggtaat gaaacacatt ttactggaag tgaagtcggt tttctcaagc
      361 ccatatcttg ccgaaatgtg aatggctatt cgtacaaagt ggcagttgca ttatctctct
      421 ttttgggatg gctgggagca gatcgatttt acctcggata tcctgcctta ggcttgttaa
      481 aattttgcac cgtaggattt tgcggaattg ggagcctaat tgatttcatt cttatttcaa
      541 tgcagattgt tggaccttca gatggaagta gttacattat agactattat ggaaccaggc
      601 ttacaagact cagcattact aatgaaacat ttagaaaaac ccagctgtac ccataagtgt
      661 ttaaaaagat aaacagattt gagcctccct gatttcaatc aagagccctg tgtgtggaat
      721 tccagatttt tcttttcctt taatatcact ttatgggttc tagatgatgt tttgacatgt
      781 gctcaacctt gatttgttga tttagttaaa atatactatt cctagattta tttaacagtc
      841 tttcttaaaa tcagtatact attttagtgg acttctgtct ctatgagaca gctagtccat
      901 tactgttact attgtattac tgtcatgttc tttacatgtc acttgtcatt tttatttgtg
      961 aaaaataaaa agataattta ttcacaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1021 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
