LOCUS       NM_001177439            1151 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus TBC/LysM associated domain containing 2 (Tldc2), mRNA.
ACCESSION   NM_001177439 XM_357232
VERSION     NM_001177439.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1151)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1151)
  AUTHORS   Finelli,M.J., Sanchez-Pulido,L., Liu,K.X., Davies,K.E. and
            Oliver,P.L.
  TITLE     The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif
            (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against
            Oxidative Stress
  JOURNAL   J Biol Chem 291 (6), 2751-2763 (2016)
   PUBMED   26668325
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669828.13.
            
            On Mar 5, 2019 this sequence version replaced NM_001177439.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363660.568591.1,
                                           SRR9219381.43932.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                AL669828.13        5349-5426
            79-225              AL669828.13        6793-6939
            226-378             AL669828.13        7463-7615
            379-474             AL669828.13        9970-10065
            475-548             AL669828.13        13635-13708
            549-1151            AL669828.13        14685-15287
FEATURES             Location/Qualifiers
     source          1..1151
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.99 cM"
     gene            1..1151
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /note="TBC/LysM associated domain containing 2"
                     /db_xref="GeneID:383766"
                     /db_xref="MGI:MGI:2686178"
     exon            1..78
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /inference="alignment:Splign:2.1.0"
     exon            79..225
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /inference="alignment:Splign:2.1.0"
     exon            226..378
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /inference="alignment:Splign:2.1.0"
     exon            379..474
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /inference="alignment:Splign:2.1.0"
     exon            475..548
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /inference="alignment:Splign:2.1.0"
     exon            549..1151
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1130..1135
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /note="hexamer: AATAAA"
     polyA_site      1150
                     /gene="Tldc2"
                     /gene_synonym="Gm1332"
                     /note="major polyA site"
ORIGIN      
        1 cttggccagg cccaaggact ctaccctgtc ctgagctgtg acagaatgaa aggctggcaa
       61 tggcggtaca ctcagctgcc cacagagatg gaggacacac tgtctgggga ggagggtgag
      121 gaggaggaag aggaggagcc agccccagcc ccagcccccc aggaccctgt ggagcctcag
      181 cttacagaag ctagccaagt cctaggtgcc tcggagatta agcagctcag cctccatctg
      241 cccccaagag tcactggcca cccctggagt ctggtcttct gcacatcaag ggatggcttc
      301 agtctgcgga gactataccg acagatggag ggtcacagtg ggccagtact gctgctgctg
      361 agagatcagg atggacagat gtttggcgcc ttctcctcct cagctatccg actcagcaaa
      421 ggcttctacg gtactggaga gacattcctc ttctccttct ccccacagct aaaggtcttt
      481 aagtggacag ggcacaactc tttttttgtg aaaggagacc tggactcact gatgatgggc
      541 agtggaagtg gccagtttgg gctgtggctg gacggagacc tgtaccatgg cggaagctac
      601 ccctgtgcga ccttcaacaa tgaagtgctg gcccgcaggg agcagttctg catcaaggag
      661 ctggaggcct gggttctgag ctgacgcctc ccgggcctcc tcacacaggg cagccattct
      721 gcccaactca ggatggggaa gaaccctcat gtggactgtg gctctcagcc agcctcctta
      781 tggcttgaaa acccaagaac aggggcagcc actgctcttc agcagagctg attataaggt
      841 gtgaaagaca ttgactgaag aagcatacaa tttgtcttta tgggatttga caatccctag
      901 aagatcaaaa aacaaaacaa acaaagcaaa aatcctaccc ctcccccata acatattcat
      961 attaagtcaa gtcgggtgta tgcacggtgt gcacacacat gcacaggcac gcacgcgcac
     1021 acacacacac acacacacac acacacacac acacactcgc actcgcactt ctcttttgtg
     1081 tttgagagat tacttttact ttaagagcct gggttccact tctaaaacta ataaagagaa
     1141 gcatcattca c
//
