LOCUS       NM_027773               2054 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus TLC domain containing 3A (Tlcd3a), transcript variant
            1, mRNA.
ACCESSION   NM_027773 XM_001003861 XM_282971 XM_911951
VERSION     NM_027773.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2054)
  AUTHORS   Garcia-Frigola,C., Burgaya,F., Calbet,M., Lopez-Domenech,G., de
            Lecea,L. and Soriano,E.
  TITLE     A collection of cDNAs enriched in upper cortical layers of the
            embryonic mouse brain
  JOURNAL   Brain Res Mol Brain Res 122 (2), 133-150 (2004)
   PUBMED   15010206
REFERENCE   2  (bases 1 to 2054)
  AUTHORS   Bleul,C.C. and Boehm,T.
  TITLE     Laser capture microdissection-based expression profiling identifies
            PD1-ligand as a target of the nude locus gene product
  JOURNAL   Eur J Immunol 31 (8), 2497-2503 (2001)
   PUBMED   11500834
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591129.24.
            
            On Dec 6, 2019 this sequence version replaced NM_027773.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160183.1, AK077374.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               AL591129.24        163379-163542
            165-248             AL591129.24        163839-163922
            249-450             AL591129.24        166541-166742
            451-546             AL591129.24        168415-168510
            547-2054            AL591129.24        169197-170704
FEATURES             Location/Qualifiers
     source          1..2054
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.92 cM"
     gene            1..2054
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /note="TLC domain containing 3A"
                     /db_xref="GeneID:116972"
                     /db_xref="MGI:MGI:2151840"
     exon            1..164
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..816
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /note="isoform a is encoded by transcript variant 1;
                     whn-dependent transcript 3; protein FAM57A; TLC
                     domain-containing protein 3A; family with sequence
                     similarity 57, member A"
                     /codon_start=1
                     /product="TLC domain-containing protein 3A isoform a"
                     /protein_id="NP_082049.1"
                     /db_xref="CCDS:CCDS36230.1"
                     /db_xref="GeneID:116972"
                     /db_xref="MGI:MGI:2151840"
                     /translation="MLLTLASGALFFPGLFALSIWALHRLRPGWTEDDCLTVGTRLVS
                     SVQAVLATWAGLTVIISCKNVVSDRHWLATEYVWFLIPYMIYDFYAMYCCERCRTKSQ
                     KLTRTTIIRNFLIENRLMVTHHTVILLFLVPISQKLRGDLGDFFVGCIFTAELSTPFV
                     SLARIMIQLKQQHTLLYKVNGILTVTTFLFCRILLFPFMYWSYGQQKGLSLLQVPFNI
                     PLHCNMANAVLISPQLYWFSLLCKKAARLFDTAKAKKDG"
     exon            165..248
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /inference="alignment:Splign:2.1.0"
     exon            249..450
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /inference="alignment:Splign:2.1.0"
     exon            451..546
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /inference="alignment:Splign:2.1.0"
     exon            547..2054
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2032..2037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /note="hexamer: ATTAAA"
     polyA_site      2054
                     /gene="Tlcd3a"
                     /gene_synonym="2310047D13Rik; 4932415L08Rik;
                     5430402E13Rik; 5430420K21Rik; Fam57a; Wdt3"
                     /note="major polyA site"
ORIGIN      
        1 agcccggagc acgccgcgca gcgagcggcc gcacccgcat ccatgctgct gactctagcc
       61 agcggcgcgc tcttcttccc cgggctcttc gcgctcagca tctgggcgct gcaccgtttg
      121 cggcccggat ggacggaaga cgactgcctg acggtcggca ccaggttagt gtcctcagtg
      181 caggcagtgc tggccacctg ggcggggctc accgtcatca tctcctgcaa gaacgtggtc
      241 tcagacaggc actggcttgc cacagaatat gtctggtttt tgattccata tatgatctat
      301 gacttctatg ccatgtactg ctgcgaacgg tgccgaacca aaagccagaa actcacacgc
      361 accaccatta tccgaaactt cctgattgaa aaccgcctta tggtcacaca tcacacggtc
      421 attctgttat tccttgtacc tatttcacag aagctccgag gagaccttgg agacttcttt
      481 gtcggatgca tcttcacagc agaattgagt actccgtttg tgtcgctggc cagaataatg
      541 atccagctaa agcagcagca tacgcttctt tacaaggtca atggaatcct cacggtgacc
      601 acctttctgt tctgccggat ccttctgttc ccattcatgt actggtccta tggccaacaa
      661 aaaggactaa gcctgctcca agtgccattt aatatccctt tacactgcaa catggccaat
      721 gccgtcctca tctctcccca gctctactgg ttctcactgc tgtgcaagaa ggcggcccgg
      781 ctctttgaca ctgccaaagc caaaaaggat ggttaattac tctcaggggt caggcactca
      841 cactagctgc ctcagtattc caaggaccaa atcatgcctg gggtagtctc tgccttctgg
      901 atgttgataa acctctggat ttttggtctt cttttttaaa aatccccatt acctcctcct
      961 tctaaccagc cttttgcaaa agcacttttt gttttgtttt ctggtgataa cttggatcct
     1021 gtcaaagccc cactgcagta gttttaccag caagcctgag gagccttcct tgggcctggg
     1081 aaagagtttt gggaggtgaa gcactgttct ccccttccca cccactcagg gcaacacccg
     1141 gcaacaccca tactgggtca gaagcaagtg acaacttggt tcttgaaact gtgtcatttt
     1201 ccaatactag gaaagacatc gtgggtatgt cttttaccgt ttactagaca gcccttgtcc
     1261 ttatctgtat atcaacaatg aattctcatg cctgctgact tctagtcaga agggctcact
     1321 gacaatgggc aggaggcagg gctgagaacc tgaagcactt gagtaggtca ggaggccagc
     1381 agaggccagc atctttgcag gctttgtata aagaccagta tcaaacttgt gagcttcttg
     1441 aaagcagtta cctacaccat ttctcctttt tagcatggcc tctcatgacc agttttctgt
     1501 gtccacacac accaaaaact ggcctgaaac tccagggaca aggtggagtg atggcttcta
     1561 tagcagctta ctgggtaatc ccacactgac actgcccttt catacaaaat ggacacagac
     1621 gtctgctctc caggtgtcct gtaggccagt gcttcctgct aagacagacc catttctgtg
     1681 ttgaatgttc tagccacaga aagcttgaaa acaggagaga gaagccagac gagccagagc
     1741 atgtcctgtg gaccagtgct gtttgttagc tgtgtgctgt agcatgtggt gtagcacaga
     1801 tcatctctca ccacaggctg gggttgagag gacctgctgc cactacttca ggtggcagca
     1861 aaaacactac agtgccttat aattcactgt ccatggactt ctaaaggact ggatggttgc
     1921 atctcaattt ttgagtttca gtctttaata ggtgccattt aaaaaacata aaaaatgctg
     1981 ttttgtgttt ttttgttctg tttactgtat ccacaagtca tccatatagt aattaaattg
     2041 cactaaattc tcta
//
