LOCUS       NM_026708               1454 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus TLC domain containing 1 (Tlcd1), transcript variant 1,
            mRNA.
ACCESSION   NM_026708
VERSION     NM_026708.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   2  (bases 1 to 1454)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591070.19, AK165432.1, AK161721.1 and BQ175335.1.
            
            On Mar 29, 2014 this sequence version replaced NM_026708.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161721.1, BC005702.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AL591070.19        171276-171332       c
            58-100              AK165432.1         5-47
            101-922             AK161721.1         1-822
            923-1454            BQ175335.1         1-532               c
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..1454
                     /gene="Tlcd1"
                     /note="TLC domain containing 1"
                     /db_xref="GeneID:68385"
                     /db_xref="MGI:MGI:1915572"
     exon            1..399
                     /gene="Tlcd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..949
                     /gene="Tlcd1"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; TLC domain-containing protein 1; calfacilitin"
                     /codon_start=1
                     /product="TLC domain-containing protein 1 isoform a
                     precursor"
                     /protein_id="NP_080984.1"
                     /db_xref="CCDS:CCDS25092.1"
                     /db_xref="GeneID:68385"
                     /db_xref="MGI:MGI:1915572"
                     /translation="MPLLFHPAWPLLLGATLTFRALRRVLCRLPQPAHVQTDPLRTWR
                     WHNLLVSFTHSIVSGIWALLCLWQTPEMLVEIETAWSASGYLLVCFSAGYFIHDTVDI
                     VVSKQTRASWEYLVHHVMAMGAFFSGIFWKRFVGGGVLTLLVEVSNIFLTLRMMMKIN
                     NAQDLLLYKVNKYINLVMYFLFRLAPQAYLTKFFLQYAGQRTLGTFLLAILLMLDLMI
                     IIYFSRLLRSDFCPERAPRRQQKDKFLTE"
     exon            400..482
                     /gene="Tlcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            483..565
                     /gene="Tlcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            566..1439
                     /gene="Tlcd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1007..1012
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tlcd1"
                     /note="hexamer: CATAAA"
     polyA_site      1029
                     /gene="Tlcd1"
     polyA_site      1100
                     /gene="Tlcd1"
                     /note="major polyA site"
     regulatory      1371..1376
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tlcd1"
                     /note="hexamer: AATAAA"
     polyA_site      1395
                     /gene="Tlcd1"
ORIGIN      
        1 ggggcgaggg cggcaggggc gggcagaggc ctcactggga acgcggggag gagcgaaggg
       61 gccttgaggg ctccgcgaaa ctgtggggct ggcggcccgc ggcagaaacg atcgtggcgc
      121 gctggccaga gaaggaacgg tgttcccaga actgtcggag gagacggctt aaggggcgga
      181 cagacagacg gcaggaaggg tcagcatgcc cctactgttc caccccgcct ggccgctgct
      241 cctgggcgcc acgctgacct tccgggcact ccggcgcgtg ctctgtcgcc tgccccagcc
      301 tgcacacgtg caaaccgacc ccctgcgcac ctggcgttgg cacaacctac tcgtctcttt
      361 cacccactcc attgtatcag ggatctgggc actgctgtgc ttatggcaaa cccctgaaat
      421 gctggtggag attgaaacag cgtggtcagc ttctggctat ttgcttgttt gcttctctgc
      481 aggatacttt atccacgaca cagtggacat tgtggttagc aagcaaactc gagcttcttg
      541 ggaatacctt gttcatcatg tcatggctat gggcgccttc ttctctggta tcttttggaa
      601 aagatttgtt ggtggtggcg tcttaacact actggtagag gtcagcaaca tcttcctcac
      661 cttaaggatg atgatgaaga taaacaatgc tcaggatctc ctcctctaca aggtcaacaa
      721 gtatatcaac ttggtcatgt acttcctctt ccgattggcc cctcaggcct acctcaccaa
      781 gttcttccta cagtatgctg gccagaggac cctgggcaca ttcttgttgg ccatcctgct
      841 catgctggac ttgatgataa tcatctactt ttctcgcctc ctccgctctg atttctgccc
      901 tgaacgtgca cccaggcgcc aacaaaaaga caaattcttg actgagtgag aaagtagaac
      961 ccaggacttg taaaagggat ggcaagcaca gccaattgct ctgtaacata aactagtact
     1021 ctgccccaag cttgggtgta ttctggggcc agcctttcca ccttaagctt acacccacac
     1081 tattgaaaac actaatgaaa gctctctgaa gtcctgttct tgggcaaggg ttgagggaag
     1141 cagaccaacc ggttgggcat ggctaaatgg gtgaggacaa gacactgtcc aaaagcctgc
     1201 caacccatac tgccctgaaa tggatgctga caattctaaa ataacccctc tgctcttcca
     1261 aaccctggta ttggtttcac accagcctgt agcagggaag gaattcttgt aaagcttgtc
     1321 ctttgagcct gtgatggagc agtgtcccag gagaaccaac acctgtctat aataaatgac
     1381 cctggtactg agctagcatg gggactgcat catcatgtgt ccccattggg ttaagcaaaa
     1441 aaaaaaaaaa aaaa
//
