LOCUS       NM_031379               2485 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus transketolase-like 1 (Tktl1), mRNA.
ACCESSION   NM_031379
VERSION     NM_031379.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2485)
  AUTHORS   He,Y., Chen,Q., Dai,J., Cui,Y., Zhang,C., Wen,X., Li,J., Xiao,Y.,
            Peng,X., Liu,M., Shen,B., Sha,J., Hu,Z., Li,J. and Shu,W.
  TITLE     Single-cell RNA-Seq reveals a highly coordinated transcriptional
            program in mouse germ cells during primordial follicle formation
  JOURNAL   Aging Cell 20 (7), e13424 (2021)
   PUBMED   34174788
REFERENCE   2  (bases 1 to 2485)
  AUTHORS   Sharma,S., Wang,J., Cortes Gomez,E., Taggart,R.T. and Baysal,B.E.
  TITLE     Mitochondrial complex II regulates a distinct oxygen sensing
            mechanism in monocytes
  JOURNAL   Hum Mol Genet 26 (7), 1328-1339 (2017)
   PUBMED   28204537
REFERENCE   3  (bases 1 to 2485)
  AUTHORS   Bulusu,V., Prior,N., Snaebjornsson,M.T., Kuehne,A., Sonnen,K.F.,
            Kress,J., Stein,F., Schultz,C., Sauer,U. and Aulehla,A.
  TITLE     Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to
            Mouse Embryo Mesoderm Development
  JOURNAL   Dev Cell 40 (4), 331-341 (2017)
   PUBMED   28245920
REFERENCE   4  (bases 1 to 2485)
  AUTHORS   Miyata,H., Castaneda,J.M., Fujihara,Y., Yu,Z., Archambeault,D.R.,
            Isotani,A., Kiyozumi,D., Kriseman,M.L., Mashiko,D., Matsumura,T.,
            Matzuk,R.M., Mori,M., Noda,T., Oji,A., Okabe,M.,
            Prunskaite-Hyyrylainen,R., Ramirez-Solis,R., Satouh,Y., Zhang,Q.,
            Ikawa,M. and Matzuk,M.M.
  TITLE     Genome engineering uncovers 54 evolutionarily conserved and
            testis-enriched genes that are not required for male fertility in
            mice
  JOURNAL   Proc Natl Acad Sci U S A 113 (28), 7704-7710 (2016)
   PUBMED   27357688
REFERENCE   5  (bases 1 to 2485)
  AUTHORS   Hamamoto,G., Suzuki,T., Suzuki,M.G. and Aoki,F.
  TITLE     Regulation of transketolase like 1 gene expression in the murine
            one-cell stage embryos
  JOURNAL   PLoS One 9 (1), e82087 (2014)
   PUBMED   24392079
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2485)
  AUTHORS   Bentz,S., Pesch,T., Wolfram,L., de Valliere,C., Leucht,K.,
            Fried,M., Coy,J.F., Hausmann,M. and Rogler,G.
  TITLE     Lack of transketolase-like (TKTL) 1 aggravates murine experimental
            colitis
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 300 (4), G598-G607 (2011)
   PUBMED   21233279
  REMARK    GeneRIF: TKTL1 plays a role during mucosal repair and restoration.
REFERENCE   7  (bases 1 to 2485)
  AUTHORS   Gallardo,T.D., John,G.B., Shirley,L., Contreras,C.M., Akbay,E.A.,
            Haynie,J.M., Ward,S.E., Shidler,M.J. and Castrillon,D.H.
  TITLE     Genomewide discovery and classification of candidate ovarian
            fertility genes in the mouse
  JOURNAL   Genetics 177 (1), 179-194 (2007)
   PUBMED   17660561
  REMARK    GeneRIF: Transcripts highly enriched in ovary; gene identified as
            candidate female fertility factor.
REFERENCE   8  (bases 1 to 2485)
  AUTHORS   Wang,P.J., Page,D.C. and McCarrey,J.R.
  TITLE     Differential expression of sex-linked and autosomal
            germ-cell-specific genes during spermatogenesis in the mouse
  JOURNAL   Hum Mol Genet 14 (19), 2911-2918 (2005)
   PUBMED   16118233
  REMARK    GeneRIF: Germ-cell-specific sex-linked genes, like Tktl1, are
            subject to meiotic sex-chromosome inactivation (MSCI) during
            spermatogenesis.
REFERENCE   9  (bases 1 to 2485)
  AUTHORS   Wang,P.J., McCarrey,J.R., Yang,F. and Page,D.C.
  TITLE     An abundance of X-linked genes expressed in spermatogonia
  JOURNAL   Nat Genet 27 (4), 422-426 (2001)
   PUBMED   11279525
  REMARK    GeneRIF: Tktl1 is a gene that is expressed in testis that was
            identified in a genome-wide cDNA subtraction screen.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK029546.1, AF285571.1 and BX512243.1.
            
            On Feb 8, 2007 this sequence version replaced NM_031379.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK139841.1, AK029546.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1214              AK029546.1         2-1215
            1215-2464           AF285571.1         1190-2439
            2465-2485           BX512243.1         341-361
FEATURES             Location/Qualifiers
     source          1..2485
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.83 cM"
     gene            1..2485
                     /gene="Tktl1"
                     /note="transketolase-like 1"
                     /db_xref="GeneID:83553"
                     /db_xref="MGI:MGI:1933244"
     exon            1..165
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            166..280
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            281..378
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            379..570
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            571..698
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            699..892
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1057
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1214
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1345
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1429
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1526
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1646
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..2471
                     /gene="Tktl1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2451..2456
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tktl1"
                     /note="hexamer: AATAAA"
     polyA_site      2471
                     /gene="Tktl1"
                     /note="major polyA site"
ORIGIN      
        1 gtttagttct gcggcacaac gtagaggaag gatgtcggaa gctgaggcaa gcagtgggat
       61 ggcccacaac gctggacctg atgagaagac attgcaggtg ttgcgggaca tggccaaccg
      121 cctgcgaatc cgttccatca aggccacaaa ttcctcgacc actagctatc tcataccatg
      181 cagcaatgct gagatcatgt ctgtgctgtt cttttataca atgagatata aacaagaaga
      241 ccctgaaaac ccagacaatg accggtgcat cctttcaaag ggactaccat ttgttaatgt
      301 ggcaacagga tggcctggac aaggactagg ggctgcctgt gggatggcat atactggcaa
      361 gtactttgac caagccagct accgggtgtt ctgtcttctg ggggatgagg aatccacaga
      421 aggctctgtt tgggaggcat ttgcctttgc atcctactac aatttggaca atcttatggc
      481 aatctttgat gtgaaccgca ttggacacag tagctccatg tctgttgagc actgcattgc
      541 catctaccag aagcgttgtg aagcctttgg gtggaatact tacgtggtgg atggccgtga
      601 tgtcaagacc ctgtgccatg tattctcaca ggcagctcaa gtgagaggca agcccactgc
      661 tgtggttgcc aaaaccttca aggcccgagg catgccaaat gttgaggatg cggaaagttg
      721 gtatggaagg ccaatgccaa aagaaagagc agatgcaatt gtcaagttaa ttgagagcca
      781 gatacagacc aacaaaattc ttgtaccatc accccctatt gaggactcgc ctcaaattaa
      841 catcatgaat atatgtatga cttcgccccc tgtttacgta gctgatgaca aggtgtctac
      901 tcaaagagca tgtggtttgg ctctagctaa actgggccat gaaaatgaca gagttattgt
      961 gctgggtagt gacaccaaga actgcaattt ttctgacata ttcaagaaag aacacccaga
     1021 gagattcatc cagtgttgta ttgctgaaca aaacatggta aatgtggctc taggatgctc
     1081 cacccgtgac cggaccattg tttttgctta ctccttcgct gcctttttca cccgagcatt
     1141 tgatcagatc cgattgggag ccatctctca aatcaacatc aaccttattg gttgtcactg
     1201 cggggtatct actggtgatg acaaccctta ccatatggcc ctggaagacc tggccatgtt
     1261 ccgagcaatt cccaattgtg ttgttttcta tccaagtgat gccgtctcca cagaacatgc
     1321 tgtttactta gcagccaata ctaaggaaat gtgctttatt cgtaccagcc aagcagaaac
     1381 tgcaattatt tacaccactc aagaaacctt tcagattgga caggccaagg ttgtccgcca
     1441 tagtgacaat gacaaggtca tagttattgg agcaggagtc accctgcatg aagccctagt
     1501 agctgctgct gagctctcta aagaagatat atctatccgt gtcattgact tgtttaccat
     1561 taaacctctg gacattgcca ccatcatttc caatgcaaaa gccacaggtg gccgaattat
     1621 caccgtggag gatcactatc ctgaaggtgg cattggagga gctgtctgtg cagcagtctc
     1681 catggagcct aacattgtgg ttcataacct ggcagtaatg gatgtgcctc gtagtggaag
     1741 atgcaatgaa gcactagatt tttctggaat cagttccaga cacatcattg tggctgtgaa
     1801 atgcatctta atgacctaaa ttagctgttg tctttggtct gagaagacta gcctcttctc
     1861 tgtatgttta tgcttgtgcc aaaaccatca attagataga aatgatgatt gcgctttgtt
     1921 ctccttaaag gcaaaaccag ttaacacctt tgttccacat tcagaaattc taattcccct
     1981 ctaatctgtg actacacata caaatatcac tgttttaacc atcaaagggg ttataagatt
     2041 tataatggca gaatagataa caagacaact acctgacact gaactttctc ataagactga
     2101 atataagtgg attaaggaac aatgtagaag tgacagtttg gaagtatttt cttcataagt
     2161 aaagcaaatg tgtgttgaat tgtagtccgc agcccacctt tcacagaact agacccccga
     2221 gatacatagt gctgttcaac ttgagttacc atgtacactg cctgcaggtt cctgagttat
     2281 gtgtaatttc agatgctctt gatttttctc tgctgtttcc ctttatatcc cctccacagt
     2341 tcacaggttg atgaacagaa caaaagcagt tatgatcact tgtgctgttg tgatgactgt
     2401 tctgtgaaga cgtaaggaca cttgatctcc acactatgct gtttgatgtt aataaagcat
     2461 ttaaaaaacc aaaaaaaaaa aaaaa
//
