LOCUS       NM_001286203             899 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus translocase of inner mitochondrial membrane 9 (Timm9),
            transcript variant 4, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001286203
VERSION     NM_001286203.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  AUTHORS   Georgas,K., Rumballe,B., Valerius,M.T., Chiu,H.S.,
            Thiagarajan,R.D., Lesieur,E., Aronow,B.J., Brunskill,E.W.,
            Combes,A.N., Tang,D., Taylor,D., Grimmond,S.M., Potter,S.S.,
            McMahon,A.P. and Little,M.H.
  TITLE     Analysis of early nephron patterning reveals a role for distal RV
            proliferation in fusion to the ureteric tip via a cap
            mesenchyme-derived connecting segment
  JOURNAL   Dev Biol 332 (2), 273-286 (2009)
   PUBMED   19501082
REFERENCE   3  (bases 1 to 899)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   4  (bases 1 to 899)
  AUTHORS   Muhlenbein,N., Hofmann,S., Rothbauer,U. and Bauer,M.F.
  TITLE     Organization and function of the small Tim complexes acting along
            the import pathway of metabolite carriers into mammalian
            mitochondria
  JOURNAL   J Biol Chem 279 (14), 13540-13546 (2004)
   PUBMED   14726512
REFERENCE   5  (bases 1 to 899)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 899)
  AUTHORS   Bauer,M.F., Rothbauer,U., Muhlenbein,N., Smith,R.J., Gerbitz,K.,
            Neupert,W., Brunner,M. and Hofmann,S.
  TITLE     The mitochondrial TIM22 preprotein translocase is highly conserved
            throughout the eukaryotic kingdom
  JOURNAL   FEBS Lett 464 (1-2), 41-47 (1999)
   PUBMED   10611480
REFERENCE   7  (bases 1 to 899)
  AUTHORS   Jin,H., Kendall,E., Freeman,T.C., Roberts,R.G. and Vetrie,D.L.
  TITLE     The human family of Deafness/Dystonia peptide (DDP) related
            mitochondrial import proteins
  JOURNAL   Genomics 61 (3), 259-267 (1999)
   PUBMED   10552927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159620.2, AF150101.1 and AI848414.1.
            
            On Nov 1, 2013 this sequence version replaced NM_001286203.1.
            
            Transcript Variant: This variant (4) lacks an internal exon in the
            5' UTR, compared to variant 1. All variants encode the same
            protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO799389.1, CA461997.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                AC159620.2         121422-121462
            42-759              AF150101.1         1-718
            760-899             AI848414.1         1-140               c
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 29.39 cM"
     gene            1..899
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /note="translocase of inner mitochondrial membrane 9"
                     /db_xref="GeneID:30056"
                     /db_xref="MGI:MGI:1353436"
     exon            1..121
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /inference="alignment:Splign:2.1.0"
     exon            122..207
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /inference="alignment:Splign:2.1.0"
     exon            208..272
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..503
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /note="translocase of inner mitochondrial membrane 10
                     homolog; translocase of inner mitochondrial membrane 9
                     homolog"
                     /codon_start=1
                     /product="mitochondrial import inner membrane translocase
                     subunit Tim9"
                     /protein_id="NP_001273132.1"
                     /db_xref="CCDS:CCDS25962.1"
                     /db_xref="GeneID:30056"
                     /db_xref="MGI:MGI:1353436"
                     /translation="MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPE
                     EVTCSEHCLQKYLKMTQRISVRFQEYHIQQNEALAAKAGLLGQPR"
     exon            273..368
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /inference="alignment:Splign:2.1.0"
     exon            369..883
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      865..870
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /note="hexamer: AATAAA"
     polyA_site      883
                     /gene="Timm9"
                     /gene_synonym="2810011L15Rik; Tim10a; Timm10"
                     /note="major polyA site"
ORIGIN      
        1 acgtgttctc agctttccgc ggcgcggcgc tcgctctgta ctgaccctcc gagctcacac
       61 gctacctgcc ccgcagctct tcagcccggt cccggtgtca gaggcgagat cctgtggcta
      121 agtaagaaat ccagtctcac tgaagacaag cagaaggcgg ggcacttgct tttccagagc
      181 agaaaagaaa ctgatgcatc agaaaaggtg actaataaac atactgaaag aatatggctg
      241 cacagatacc ggaatctgac cagataaaac agtttaagga gttcctggga acctacaata
      301 aacttacaga aacctgcttt ttggactgtg ttaaagactt cacaacaaga gaggtgaaac
      361 ctgaagaggt gacctgttca gaacattgct tacagaaata tttaaaaatg acacagagga
      421 tatccgtgag atttcaggaa tatcacattc agcagaatga agccctggca gccaaagcag
      481 gcctcctggg ccagccacgg tagagaggtc ctgaggcggg gacttgcact gaaagattgc
      541 cagcagctgc tgcagtcaga acaaggattc acatggtgga gaatcccctg acacagcagg
      601 agccgtggtc caccatctgt catgactacc tgaccaatgg aaaccaccag agaaaaacac
      661 tgttcaccag aaagagtcaa aacagaaggc cttcctgtgc ggtaaaaatg gtaagatgcg
      721 gtggtgttga ggccttaaga ttcgtctgcg tggtcaccgt gattgcaaaa ataaaccact
      781 gttcctttct ttgtgactgt taattttaaa gcaaaatatg tgtccaatca tgtatgagat
      841 agaaaaagtt tattactaaa agtaaataaa tgagtatcat tgaaaaaaaa aaaaaaaaa
//
