LOCUS       NM_011591               1703 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus translocase of inner mitochondrial membrane 17b
            (Timm17b), transcript variant 1, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_011591
VERSION     NM_011591.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1703)
  AUTHORS   Bebee,T.W., Park,J.W., Sheridan,K.I., Warzecha,C.C., Cieply,B.W.,
            Rohacek,A.M., Xing,Y. and Carstens,R.P.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1703)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   3  (bases 1 to 1703)
  AUTHORS   Means,G.D., Toy,D.Y., Baum,P.R. and Derry,J.M.
  TITLE     A transcript map of a 2-Mb BAC contig in the proximal portion of
            the mouse X chromosome and regional mapping of the scurfy mutation
  JOURNAL   Genomics 65 (3), 213-223 (2000)
   PUBMED   10857745
REFERENCE   4  (bases 1 to 1703)
  AUTHORS   Bauer,M.F., Gempel,K., Reichert,A.S., Rappold,G.A., Lichtner,P.,
            Gerbitz,K.D., Neupert,W., Brunner,M. and Hofmann,S.
  TITLE     Genetic and structural characterization of the human mitochondrial
            inner membrane translocase
  JOURNAL   J Mol Biol 289 (1), 69-82 (1999)
   PUBMED   10339406
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671978.2, AK049584.1 and AL670169.9.
            
            On Aug 25, 2015 this sequence version replaced NM_011591.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049584.1, AW342126.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                AL671978.2         55633-55694
            63-1309             AK049584.1         2-1248
            1310-1310           AL670169.9         9334-9334
            1311-1418           AK049584.1         1250-1357
            1419-1419           AL670169.9         9443-9443
            1420-1703           AK049584.1         1359-1642
FEATURES             Location/Qualifiers
     source          1..1703
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 3.56 cM"
     gene            1..1703
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /note="translocase of inner mitochondrial membrane 17b"
                     /db_xref="GeneID:21855"
                     /db_xref="MGI:MGI:1343176"
     exon            1..134
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..627
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     translocator of inner mitochondrial membrane b;
                     translocator of inner mitochondrial membrane 17b;
                     mitochondrial import inner membrane translocase subunit
                     Tim17-B; translocator of inner mitochondrial membrane 17
                     kDa, b"
                     /codon_start=1
                     /product="mitochondrial import inner membrane translocase
                     subunit Tim17-B isoform 1"
                     /protein_id="NP_035721.1"
                     /db_xref="CCDS:CCDS29978.1"
                     /db_xref="GeneID:21855"
                     /db_xref="MGI:MGI:1343176"
                     /translation="MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGI
                     RHRFRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSISSGALTGAV
                     LAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLTPKEGS
                     PAPGYPNYQQYH"
     exon            135..234
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /inference="alignment:Splign:2.1.0"
     exon            235..298
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /inference="alignment:Splign:2.1.0"
     exon            299..427
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /inference="alignment:Splign:2.1.0"
     exon            428..538
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /inference="alignment:Splign:2.1.0"
     exon            539..1703
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      918
                     /gene="Timm17b"
                     /gene_synonym="17kDa; mTim17b; Sfc3"
                     /note="major polyA site"
ORIGIN      
        1 ttggtctacg tacagcgcct cagagcttgt gggcgtttcg gagcgggagg gggacggggg
       61 gagtgtctcg cccgcgccac cgactgcgcc aggccggact ctggcgccat ggaggagtac
      121 gctcgcgaac cttgcccatg gcgaattgtg gatgattgcg gtggagcttt caccatgggt
      181 gtcattggtg gtggagtctt ccaggctatc aagggcttcc gcaatgcccc tgttggaatt
      241 cgacaccggt tcagaggtag tgtcaatgct gtgaggatcc gggcacccca gattggagga
      301 agctttgcag tgtggggagg tctgttctcc accatcgact gtggcctggt ccggctacgg
      361 ggcaaagaag acccctggaa ttccatcagc agtggagcgt tgactggagc tgtgctggct
      421 gcgcgcagtg gtccgctggc catggtgggc tctgcgatga tgggaggcat cctgttggcc
      481 ctcattgagg gtgttggcat ccttctcacc cgctatactg cccagcagtt ccgaaatgca
      541 cccccattct tggaggaccc cagccagcta accccgaaag agggatctcc ggccccaggt
      601 tatcccaact accagcagta ccactgagga agccgctgcc tgacccccgc caccgtggga
      661 gccactcctc agttccctcc cggatgatct acctccaagg gaggactggc tcctacatag
      721 ccctgagagg ccttcacaga gggcctcaat tctactctct ggttttgtgg taggggtggg
      781 gacaccccag cagccttgtc atatgggttc cctttttgtg tcttagggca tcccagcttc
      841 atacgtgtaa caattctctc acccccagag ccctcgtgtg gcaccctgat gaatgtttaa
      901 agccagtttt gaaatgtctg tgtatgtctg ccttcagtca cccagatggc cctctctctc
      961 ctcagaaggg gcttggaaag tctagggctt gagatttcat ggtgaatggg tttgaagggt
     1021 tttgatggtt tttgttttgt tttgtttttt gtattgggaa gtgggagaaa gaagcagggt
     1081 ctcagctggg catggtggca cacacctgta atcccagcac ttgggaggca gagacaggca
     1141 gatttctgag ttcaaggcca gcctggtcta cagagtgagc tccaggacag ccagggctac
     1201 acagagaaac cctgtctcaa aaacaaaaaa caaaaaaaaa gaagaagcag ggtgtcactg
     1261 tgttgtctaa actgaacttg aacttgtatg atactaccac acccaacctc tagtaaaggt
     1321 ttacaaaatg aatgagcaag ggagggaata gtcaaaaaga tgaattagac acatgcataa
     1381 acgtggttag gtgcctagac atgcttcgtg cacgcaggaa agaaggacaa ggattgctgg
     1441 gagcatgtgt atgctgtgca aacatactgc agaccctcct ggtacaggct ccccgtggag
     1501 agcatgggaa accaggcgcg tgagaaaagc ctttgccctg ggcgtggtag tgcacacttt
     1561 aatccagccc agagcagcac agaggccgaa gcggagacac acagatctct gtgagctgaa
     1621 ggacagccta gtctacagag cttatcccag gacagccacg gctgttactc agagaaccct
     1681 gtcttgaaaa acaaaagcaa acc
//
