LOCUS       NM_013899                682 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus translocase of inner mitochondrial membrane 10
            (Timm10), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_013899
VERSION     NM_013899.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Ahting,U., Floss,T., Uez,N., Schneider-Lohmar,I., Becker,L.,
            Kling,E., Iuso,A., Bender,A., de Angelis,M.H., Gailus-Durner,V.,
            Fuchs,H., Meitinger,T., Wurst,W., Prokisch,H. and Klopstock,T.
  TITLE     Neurological phenotype and reduced lifespan in heterozygous Tim23
            knockout mice, the first mouse model of defective mitochondrial
            import
  JOURNAL   Biochim Biophys Acta 1787 (5), 371-376 (2009)
   PUBMED   19111522
REFERENCE   2  (bases 1 to 682)
  AUTHORS   Muhlenbein,N., Hofmann,S., Rothbauer,U. and Bauer,M.F.
  TITLE     Organization and function of the small Tim complexes acting along
            the import pathway of metabolite carriers into mammalian
            mitochondria
  JOURNAL   J Biol Chem 279 (14), 13540-13546 (2004)
   PUBMED   14726512
REFERENCE   3  (bases 1 to 682)
  AUTHORS   Bauer,M.F., Rothbauer,U., Muhlenbein,N., Smith,R.J., Gerbitz,K.,
            Neupert,W., Brunner,M. and Hofmann,S.
  TITLE     The mitochondrial TIM22 preprotein translocase is highly conserved
            throughout the eukaryotic kingdom
  JOURNAL   FEBS Lett 464 (1-2), 41-47 (1999)
   PUBMED   10611480
REFERENCE   4  (bases 1 to 682)
  AUTHORS   Jin,H., Kendall,E., Freeman,T.C., Roberts,R.G. and Vetrie,D.L.
  TITLE     The human family of Deafness/Dystonia peptide (DDP) related
            mitochondrial import proteins
  JOURNAL   Genomics 61 (3), 259-267 (1999)
   PUBMED   10552927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK008088.1, AK013546.1 and AF150090.1.
            
            On Oct 31, 2007 this sequence version replaced NM_013899.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF162236.1, AK008088.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                AK008088.1         2-94
            94-202              AK013546.1         24-132
            203-652             AK008088.1         204-653
            653-682             AF150090.1         630-659
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.45 cM"
     gene            1..682
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /note="translocase of inner mitochondrial membrane 10"
                     /db_xref="GeneID:30059"
                     /db_xref="MGI:MGI:1353429"
     exon            1..127
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /inference="alignment:Splign:2.1.0"
     exon            128..242
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..444
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /note="translocase of inner mitochondrial membrane 13
                     homolog a; translocase of inner mitochondrial membrane 10
                     homolog"
                     /codon_start=1
                     /product="mitochondrial import inner membrane translocase
                     subunit Tim10"
                     /protein_id="NP_038927.2"
                     /db_xref="CCDS:CCDS38161.1"
                     /db_xref="GeneID:30059"
                     /db_xref="MGI:MGI:1353429"
                     /translation="MDPLRAQQLAAELEVEMMADMYNRMTSACHRKCVPPHYKEAELS
                     KGESVCLDRCVSKYLDIHERMGKKLTELSMQDEELMKRVQQSSGPA"
     exon            243..666
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      647..652
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /note="hexamer: ATTAAA"
     polyA_site      666
                     /gene="Timm10"
                     /gene_synonym="Tim13; Timm13a"
                     /note="major polyA site"
ORIGIN      
        1 gaggctagac ttccttccgg aagtgaccca cgtgcttctt atttcgcctg ccttggtacc
       61 cggtaacttt ttactattga cccgaagttg gggacgttgc gggagctgtg acctgcccca
      121 ggccgtggac taaagaccag gaggctattc tctccacggt gctaagttga catggatccg
      181 ctcagagccc agcagctggc tgcggagctg gaggtggaga tgatggctga catgtacaac
      241 agaatgacca gtgcctgcca ccggaagtgc gtgcctcccc actacaagga ggcagagctg
      301 tccaaaggcg agtctgtgtg tctggaccga tgtgtatcca agtacttgga catccatgag
      361 aggatgggca aaaagttgac agagctgtca atgcaggatg aggagctgat gaagagggta
      421 cagcagagct cggggcctgc atgacgcccc aggctgtcta cacctgaggt gtaccttgcc
      481 acttgcctga ttaaagtgtc cctaatggat gtcacatgtg aaacctgtca tacttaggcc
      541 cttgagcatc tccaggaccc ctgcgtgtag tagagctctc ctggctgaag aaggggactt
      601 gtcacgctgg tttgtgactg tgtatgtgtg tatatgtata tatcttatta aaacaaattt
      661 gtgcaaaaaa aaaaaaaaaa aa
//
