LOCUS       NM_001040426            8796 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus thrombospondin, type I, domain containing 4 (Thsd4),
            transcript variant 1, mRNA.
ACCESSION   NM_001040426
VERSION     NM_001040426.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8796)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8796)
  AUTHORS   Elbitar,S., Renard,M., Arnaud,P., Hanna,N., Jacob,M.P., Guo,D.C.,
            Tsutsui,K., Gross,M.S., Kessler,K., Tosolini,L., Dattilo,V.,
            Dupont,S., Jonquet,J., Langeois,M., Benarroch,L., Aubart,M.,
            Ghaleb,Y., Abou Khalil,Y., Varret,M., El Khoury,P., Ho-Tin-Noe,B.,
            Alembik,Y., Gaertner,S., Isidor,B., Gouya,L., Milleron,O.,
            Sekiguchi,K., Milewicz,D., De Backer,J., Le Goff,C., Michel,J.B.,
            Jondeau,G., Sakai,L.Y., Boileau,C. and Abifadel,M.
  TITLE     Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein,
            predispose to inherited thoracic aortic aneurysm
  JOURNAL   Genet Med 23 (1), 111-122 (2021)
   PUBMED   32855533
  REMARK    GeneRIF: Pathogenic variants in THSD4, encoding the ADAMTS-like 6
            protein, predispose to inherited thoracic aortic aneurysm.
REFERENCE   3  (bases 1 to 8796)
  AUTHORS   Howden,R., Cho,H.Y., Miller-DeGraff,L., Walker,C., Clark,J.A.,
            Myers,P.H., Rouse,D.C. and Kleeberger,S.R.
  TITLE     Cardiac physiologic and genetic predictors of hyperoxia-induced
            acute lung injury in mice
  JOURNAL   Am J Respir Cell Mol Biol 46 (4), 470-478 (2012)
   PUBMED   22052878
REFERENCE   4  (bases 1 to 8796)
  AUTHORS   Saito,M., Kurokawa,M., Oda,M., Oshima,M., Tsutsui,K., Kosaka,K.,
            Nakao,K., Ogawa,M., Manabe,R.I., Suda,N., Ganjargal,G., Hada,Y.,
            Noguchi,T., Teranaka,T., Sekiguchi,K., Yoneda,T. and Tsuji,T.
  TITLE     ADAMTSL6beta protein rescues fibrillin-1 microfibril disorder in a
            Marfan syndrome mouse model through the promotion of fibrillin-1
            assembly
  JOURNAL   J Biol Chem 286 (44), 38602-38613 (2011)
   PUBMED   21880733
  REMARK    GeneRIF: ADAMTSL6beta has a role in fibrillin-1 microfibril
            formation
REFERENCE   5  (bases 1 to 8796)
  AUTHORS   Salbaum,J.M., Kruger,C., Zhang,X., Delahaye,N.A., Pavlinkova,G.,
            Burk,D.H. and Kappen,C.
  TITLE     Altered gene expression and spongiotrophoblast differentiation in
            placenta from a mouse model of diabetes in pregnancy
  JOURNAL   Diabetologia 54 (7), 1909-1920 (2011)
   PUBMED   21491160
REFERENCE   6  (bases 1 to 8796)
  AUTHORS   Du,J., Takeuchi,H., Leonhard-Melief,C., Shroyer,K.R., Dlugosz,M.,
            Haltiwanger,R.S. and Holdener,B.C.
  TITLE     O-fucosylation of thrombospondin type 1 repeats restricts
            epithelial to mesenchymal transition (EMT) and maintains epiblast
            pluripotency during mouse gastrulation
  JOURNAL   Dev Biol 346 (1), 25-38 (2010)
   PUBMED   20637190
REFERENCE   7  (bases 1 to 8796)
  AUTHORS   Shimogori,T., Lee,D.A., Miranda-Angulo,A., Yang,Y., Wang,H.,
            Jiang,L., Yoshida,A.C., Kataoka,A., Mashiko,H., Avetisyan,M.,
            Qi,L., Qian,J. and Blackshaw,S.
  TITLE     A genomic atlas of mouse hypothalamic development
  JOURNAL   Nat Neurosci 13 (6), 767-775 (2010)
   PUBMED   20436479
REFERENCE   8  (bases 1 to 8796)
  AUTHORS   Tsutsui,K., Manabe,R., Yamada,T., Nakano,I., Oguri,Y., Keene,D.R.,
            Sengle,G., Sakai,L.Y. and Sekiguchi,K.
  TITLE     ADAMTSL-6 is a novel extracellular matrix protein that binds to
            fibrillin-1 and promotes fibrillin-1 fibril formation
  JOURNAL   J Biol Chem 285 (7), 4870-4882 (2010)
   PUBMED   19940141
  REMARK    GeneRIF: Results indicated that ADAMTSL-6 is a novel
            microfibril-associated protein that binds directly to fibrillin-1
            and promotes fibrillin-1 matrix assembly.
REFERENCE   9  (bases 1 to 8796)
  AUTHORS   McDaniel,A.H., Li,X., Tordoff,M.G., Bachmanov,A.A. and Reed,D.R.
  TITLE     A locus on mouse Chromosome 9 (Adip5) affects the relative weight
            of the gonadal but not retroperitoneal adipose depot
  JOURNAL   Mamm Genome 17 (11), 1078-1092 (2006)
   PUBMED   17103052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK138976.1 and AC131749.2.
            
            On Jan 6, 2010 this sequence version replaced NM_001040426.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK138976.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1730              AK138976.1         2-1731
            1731-1731           AC131749.2         147425-147425       c
            1732-1984           AK138976.1         1733-1985
            1985-1985           AC131749.2         141699-141699       c
            1986-2439           AK138976.1         1987-2440
            2440-2440           AC131749.2         132498-132498       c
            2441-3997           AK138976.1         2442-3998
            3998-8796           AC131749.2         111429-116227       c
FEATURES             Location/Qualifiers
     source          1..8796
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 32.38 cM"
     gene            1..8796
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /note="thrombospondin, type I, domain containing 4"
                     /db_xref="GeneID:207596"
                     /db_xref="MGI:MGI:2672033"
     exon            1..195
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            196..303
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            304..376
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            377..738
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            739..1186
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1289
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1426
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1631
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1807
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1904
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1905..2180
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2181..2310
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..2515
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2689
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2690..2863
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2864..3043
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3044..3188
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..8796
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4417..4422
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /note="hexamer: AATAGA"
     polyA_site      4437
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /note="major polyA site"
     polyA_site      5977
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
     regulatory      8771..8776
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      8789
                     /gene="Thsd4"
                     /gene_synonym="ADAMTSL-6; Adamtsl4; ADAMTSL6;
                     B230114P05Rik"
                     /note="major polyA site"
ORIGIN      
        1 agctgggtgc agacccggct ctccagacag gagacagcag gcctgctgac tgcttccatc
       61 tccacagctc ctgggtggat cttggtttca gagattccta tgggcagaaa agtgggattc
      121 tttccagatg ggagaccacc agccctgaag gtgactgcga ggctgtggtt cttggctccc
      181 aaacctgctt tcactgagtt gaacaccact tgagcctgta gaaaactggg gacacccctg
      241 aggaacccgt gtcttagcct ggacctgcag catcatggtt tcctatctca cgagctgtct
      301 cagtgccctg agcaccctcc tgctgctgct tggttctcag cttgtctgcc cgcagccttc
      361 cactgaacac agaaaggtcc cacaacggat ggcagtgacc gagggaaccc cagaggacag
      421 tggcagtggc tccccaggtg tgtggggctc ctggggcccc tggtctgcct gttctcgcag
      481 ctgcagtggt ggtgtgatgg agcagacacg gccctgcctg cccagctcct accgtgctcg
      541 aggaggctcc cggcccaatg gccgtgcact gtccatcact ggccacgttg tgtcagccgt
      601 acggacctca gtaccactgc atcgaagcca ggaggaccaa agagccctgg ctggctccaa
      661 tgctagccgc caaggccctg cagtggtgcg aggcagccga catccacagg cccggggccg
      721 tgaaccctca gagagaagga gcaggacccg aggtcctatt ggccctggca agtatggcta
      781 tgggaaggct ccctacatct taccactgca gacggatacc acgcatactc cacagaggct
      841 tcggagacag aggccttcat ccaggcactc caggtcccag gaggcatctg cttctaagca
      901 gggctatcgg ccaccaaccc atcagttctc ccacagccaa cctctctacc agagtgacag
      961 tggccctcgc tctggactgc caccttctga ggcttctatc taccagctgc ccttgactca
     1021 cgaccaaagc tatcctgcag cgtcgagtct cttccacaga ccggaactga gcagccacca
     1081 tggtgctagg ccccacgggg cagctcaagc ctttccccag catctgcgat caacagcaat
     1141 ctcctgcatc ggggcctatc ggcagtacaa actgtgcaac accaatgcgt gtccagaaag
     1201 tggtagaagt atccgggagg tacagtgtgc atcctacaac aacaagccat tcatgggccg
     1261 gttttatgaa tgggaaccat ttgcagaagt aaagggtaat cgcaagtgtg agctgaactg
     1321 ccaggcaacc ggctaccgct tctacgtccg gcaagctgag aaggtcatcg atggcacacc
     1381 ctgtgatcag aatggcacgg caatctgtgt gtcggggcag tgcaagagca ttggctgtga
     1441 cgacttcctg ggatctgaca aagtcttgga caagtgcggg gtgtgtggag gtgataacac
     1501 gggctgccag gtggtgtcgg gagtgttcaa gcacgccctc accagcctgg gctaccaccg
     1561 ggttgtagag attccccaag gagctacgaa aattaacatt acagagatgc acaagagcaa
     1621 caactactta gccttgcgaa gtcgctctgg ccgctccatc atcaatggga actgggcaat
     1681 cgatcgcccg gggaagtacg agggcggagg gacaatgttc acctacaaac gaccgaacga
     1741 ggtctccagc actgcggggg agtcctttct ggctgagggt cccactaatg agatcctgga
     1801 tgtctatatg atacaccagc agcccaaccc aggagtccac tatgagtacg tgatcatgag
     1861 gaataatgcc atcagcccac aggtgccacc acacaggaga ccaggagaac ctttcaatgg
     1921 gcagctggaa gaggaagaca gaggccagga ggacagagaa gagagggaga agaaccagga
     1981 aaaggaagac tcacaagtcg aggcccctga ggtattcacg tcagaatcca cgcagacctt
     2041 cccagtcagg catccggaga gattcccttc ccaccgacca gacaacttgg tgcccccagc
     2101 accacagccc ccaaggcgaa gccgggacca caactggaag cagctgggga caacagaatg
     2161 ctccaccacc tgtgggaaag gatcgcagta ccctatcttc cgctgcgtgc acagaaacac
     2221 acacgaggag gttcccgaga gctactgtga ctccagcatg aagccgaccc cagaggagga
     2281 accctgcaac ctcttcccct gcccagcctt ctgggacatc ggggagtggt cggagtgcag
     2341 caagacctgt ggtctgggca tgcagcaccg ccaggtcctg tgtcgccagg tgtatgccaa
     2401 ccgtagcctg acggtgcaac cctaccgctg ccagcacctg gagaagccag agaccaccag
     2461 cacctgccag ctcaagatct gcagcgagtg gcagattcgg accgactgga cctcgtgctc
     2521 agtgccctgt ggcgtggggc agcggacccg agacgtgaag tgtgtgagca acatcgggga
     2581 catggtgcat gacgaggagt gcaacatgaa gctccggcca aatgacatcg agaactgtga
     2641 catggggccc tgtgcgaaga gctggttcct cacagagtgg agtgaaaggt gctcagcgga
     2701 gtgtggggca ggagtgagga cacgttcagt ggtgtgcatg accaaccacg tcagcagcct
     2761 gccgttggaa ggctgtggga acaacaggcc agtggaggct acgccgtgtg acaatgggcc
     2821 ctgcacaggc aaggtggagt ggttcactgg cagctggagt cagtgttcca tcgagtgtgg
     2881 cagtgggaca cagcagaggg aagtgatctg tgttaggaag aatgcagaca cctttgaagt
     2941 gctagaccct tatgagtgtt cattcctgga gaagccccca agccagcagg cctgccacct
     3001 caagccttgt ggagctaaat ggtttagcac agaatggagc atgtgctcca agagctgtca
     3061 gggcggattc cgggtgcggg aagttcggtg tctctcagat gacatgaccc caagtagcct
     3121 ctgcgacccc cagttgaaac cagaagagag agagtcttgt aacactcagg actgtgtccc
     3181 tgaagttgat gaaaactgca aggacaagta ctacaactgc aacgtggtgg tccaggcacg
     3241 cctctgtgtc tacaactact acaagactgc ctgctgtgcc tcttgcaccc gagtggctaa
     3301 cagacacgtg ggctttctgg ggagccgata acacacctgc actcctgggg ttacaagcag
     3361 tgcacccggc tggctgctgc tctgccaggg accccactct caccttcata aagccacatg
     3421 gtagccagga tgttggaaag ccatggctga ccctttgaac actgccctgt cctgatgacg
     3481 agaacttcct tgggacctgg cgcctactga tggtgccttc tgaaaatcca gcatagagct
     3541 ctcatcccaa ctccagacct gccgtcatcc agggcagcag ctggacccct gaccaagcac
     3601 agcctccttc ctggtgctac tggcctatcc aaaattagaa cccctttgga aagtcaagag
     3661 agggaaacac cccatcctgc agcatcgaca aacctgtgca cccctgatac ctcagcccag
     3721 ctgcatctgt tgccattctt aaagacaaga gacagttccc tgtctccgga cagaggtatc
     3781 tcacaacaga gtgctttttt gtttagcagg tacacacgtt ctctgacatt agctccctgg
     3841 aggctgcagc atcgcagaat gggaggcagg gggtgaatat gtgctcccac tttactagca
     3901 aggagactga ggtctactca cataactgag ttgctgtttg ggaacaaggc taagtgccta
     3961 ccccagatgg ttaagcacaa ccttctcccc acagcacctt caacctgggc tctttccagg
     4021 gcctatagtc tgaaggatga atggggcttc ctgtctgacc aggaggctga gaagtttctc
     4081 attctatgaa cagcccaggc ttctgagacc catcctctgt ccccaagtgc tgcctcaaat
     4141 gagttctttc aagatatctg cacccctgtc ccccttccct cagccacaac tcctgctgac
     4201 aggaatctgg tgtttgctaa gttccattct taacagaact gtccctggag acaagagagc
     4261 catggggaga gctggccagt tgccagggat tctctgggcc gttctggaac tggaacaaac
     4321 tcccacaggc tcttgttcta ccatctctcc tgggttcttc atggtaccac ctcgtgtaca
     4381 gccacgccag ttaaaccagc aagatgtccg tattgcaata gaaagggtct tatttgagcc
     4441 tgtggactgt ctggagtttc tatctagtgg tctcgcatcg ctcccctcca ctgtgactca
     4501 tgactctttc ttcccacaag ccttgaccat cgagactaac tttaatgctg caggtctgag
     4561 agaaggagct aggaagccct ccgtagctct gctgactcac tctgcccaac tgtaattcca
     4621 aaggcccagg cctgaaggga ctcagtgttt attgaaaggt gaaccatcct ggggtgccag
     4681 ggactgggga gagacaatta ggagaagtct tttttctttc ttaaaaattg taaacttaca
     4741 gaaaggatct tatttcgggt cctgggcatg tttcccttaa agaaagcaca tactcttagc
     4801 atacgatctc tccatgaagc agcctgcact atgaccgacc gctcacggct gtggggatgg
     4861 tataagctgt ccggtctgca cttcatgagg attccaatgg cctccacctt ttgcaagtgt
     4921 cccctcagcc tttgtctctg cctgagaagc gaagcactgc ttccatccgt aagcagccca
     4981 cctctcctgt ggagcaggag acacacagcc cagcagagac cgcactcgcc atgctaagca
     5041 cagagagaag ccaccacatg agcagcttct atccagttcc ctgcctgtcc ctctcactgt
     5101 gcctctgctt gtcctgggca gctttccctc tatgcagcca ttctcagatc ttgctggaca
     5161 agccagacat ttgaaggatt ccttggaagg tgtttgtgtg caggccggat ctgtgggtaa
     5221 aatgcaggct ggcgtcagct ccaggaaagg aaggtgttct agcaaccaaa gccacccaac
     5281 aatggatggt cacagggcct aaaggacttc tctgtggagg gtgagcgctc tggtccttca
     5341 aattcacaaa ttctcagggc tgggctgggt tagtgatggc tttgtctatc ctatgtctca
     5401 gatgtcacca cacagttctt aagaaggaca atgatcctct tgtaagtgag tgtaggtcag
     5461 agaaaatggg gcaggctctg gtctttaggc aaacaccaaa ctaaaccaaa caaaacacca
     5521 ccaacaaaac tagaaaacac ctcatctgag ttcaggggat tttttcccag ggaaatcagc
     5581 tgttcctgag agttcagtcc cattgagaag gttgcagatt tttagaatgg ggcaattaac
     5641 tactttgttt agaaggccaa tcttgcaaag gtcctggttc ctccttctgt cccctacata
     5701 gcctcctccg tacactgtgt gggcagtgtg gccttgggat ccccactgat taccagggat
     5761 ggatgcctgt ccctggagat ggtgctctat atgccacctt cttcttgggc ctcttcacat
     5821 tcccttcatt ggctgtggtt tggaactgaa attatatatt tcaatattga ttttcctctg
     5881 gtgtgccagc tggccacatc atgctctctg aatgaaaaat taggtaaatt aaagctactg
     5941 tgtagccttt ctcgacaaaa gtcaacaaag ccccaaatga aaagcgtgtg ctgtctccct
     6001 ttcactggaa aacaaaacaa aacaaaacaa aacaaaacaa aacaaaacaa aacaaccttc
     6061 cttttgagct tctattgagt ctctatttcc ctttacctct cagggcaggc tgggaatatg
     6121 ctatctggcc gctagaggga gttccctgct catagccagg ctcagcctgg ctatgctcag
     6181 ccaggggagc ttgtcagccc aggacttctg ttccgccttc cctccttgct tttagcacac
     6241 atcatctatt tgttctctac tcatttacac ccaaacttct ctttttaaac agtggctctc
     6301 taaaggactg agaaacggga gatgctagat taattcgttg tgtggtatgg agaaatctag
     6361 atatggctag cacctgccca agatagtccc ctcgtttcat taatagctgt cttagtgttg
     6421 acactataga gctttcctat aaggaacaaa atgaaacaaa acgacggtca caacagggtg
     6481 aatgatctgt cagccctgca ggtggaggcc agatccttgc cagataaaac attttgcaca
     6541 tagcttagat gtctttgaag aaaactggct gatgtcctga tcttggagag ccaatagcta
     6601 gggtaagagg gatctgaaaa gatgttataa aaaccctgac gagaaggcct gtatatgttt
     6661 caacagttcc ctgggaggtg gtgaaagtcc tacctttgga ataaaagaat aactgtacag
     6721 ttgaaaggtg ctagagaaga attccagcta agttcaaagt aaatcaaaga gtgggaggaa
     6781 gcattagaat ataaaggacc cctggactcg caagttagct cagtcagcaa agcactgaag
     6841 aactgagttg agtctcagaa cccacatgca aaaagccggg cgtggtggta ctcagttgta
     6901 atcccagcac tagggaggca gagactgaga ggatcgctgg ggctcaccag ctggccagcc
     6961 ccacctactt ggcaagttcc aggccagtga gagatggtgt ctcaaaacat ggtggatagc
     7021 acctgaagag caacaggtgt cctctgacct ccacatgaac acacacacac acacacacac
     7081 acacacacac acacacacgt gtgtaagcca ctccacaagc caccaaggcc acagagaaag
     7141 cacgggcgag ggtcaagctg gtgtctgtag gaagactact gctcacaggt aacatttaga
     7201 tggggtttcc caatcctgat aaaagaggac agcctgtcgg agacagtgtg aggaacttgt
     7261 gaggtgggat atctgcggaa gagacaccct gagagccctc tcaggagtca gagggaggaa
     7321 gttgagtgaa acaggttgtt cctatagaat ggcaagcttt ctgcaagcac cttctacggg
     7381 gcagggatgc tggagatgat aagcagctga ggcaggatgg cactgtgtca ggatgtgggg
     7441 agaggctccc caaagtggaa cagctctgag tggctcattc atatccttcc taactgctac
     7501 taccttgctg ccatttgaaa cccatcagtg cctcttcctg taagttgtgt gtgccgtcat
     7561 atggcagcca ctggcaaccc aggcagagcc atccccctgt gcctgcttca cagagggaca
     7621 aacaggcatg ggggcagcta actgcctgcc tggggtcaca acgctccacc gaggcagcct
     7681 ggactagcct gggctatttg tctccaatcc cttttgtaag aacaggctgc cttcctgagg
     7741 gactgtttgc cgacaaagag caatggcttt ctaccccaca cggtccttta tcctctgaat
     7801 cgttgttctg ttgggatccg tgctgtgctg ttctgtggaa agtggcccca agaatataga
     7861 aactcccagc cttgtcagat gatcagcccc tgcctcagtg gacaaaagtc cattctgtta
     7921 catccactaa ctcccacctt cctgagcccc ccagctctcc aacataagga tatactttgc
     7981 tataacttat tattttgttc cctgtaaata caagatgttt ataggaaata tgtattctga
     8041 actatatctg cagagtggac tgcaacacca gaatagttct gttatttaga atatgtgcat
     8101 tgtaaaggga cctaataggt atttatttac atatgccatc cacatttaca taaaattgtt
     8161 tgattggcca agccagcttc ctggcacatt gctgcaccac agtgtcttat tctatgtcaa
     8221 tccttacagt tgtttatatg gtaattggcc aaacttttgg gggtttaaaa caaaatataa
     8281 ctaactccgc ttttgacgta ttcaggggct ctccccctgg tattgtgcct gactaagcct
     8341 gccacctttc tgtcttaaat atactttctc atatgatctg ccctctcctc acacccaaac
     8401 acttggagaa ggaaaggtga ctagcccttc tcgtcccttc tcagtgtggc tggccgttag
     8461 cttcacccac ctcattgctc aggtcagagc tgtggacgcc ttgggctgag ggactgggag
     8521 aggcttgggg gcacacagca accccagggt ccctgctggg gactgtgggg gccagggcct
     8581 tgaggatgac cagtgaactg cagaattaaa actgagaaac ccgaggacac cgccagttcc
     8641 gtgtctcctc tgcaggctta agttattatg ggagggggga ggcaggtaga cggtgaatta
     8701 tatgagcaaa tatgagctgg tttccagcac tattttgtgt acaactaatt tattttcatt
     8761 gtaaaaatat aataaagtgg ttaaaagatc tgctta
//
