LOCUS       NM_001033929            2018 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus threonine synthase-like 2 (bacterial) (Thnsl2),
            transcript variant 2, mRNA.
ACCESSION   NM_001033929
VERSION     NM_001033929.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2018)
  AUTHORS   Donini,S., Percudani,R., Credali,A., Montanini,B., Sartori,A. and
            Peracchi,A.
  TITLE     A threonine synthase homolog from a mammalian genome
  JOURNAL   Biochem Biophys Res Commun 350 (4), 922-928 (2006)
   PUBMED   17034760
  REMARK    GeneRIF: In vitro, the protein encoded by BC051244 acts as a
            phospho-lyase on large, phosphorylated amino acids. For example, it
            degrades O-phospho-threonine to ketobutyrate, phosphate, and
            ammonia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX223060.1, AK165463.1, BQ042728.1 and AI156509.1.
            
            On Nov 8, 2013 this sequence version replaced NM_001033929.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK165463.1, BC051244.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                CX223060.1         1-34
            35-680              AK165463.1         1-646
            681-1282            BQ042728.1         30-631
            1283-1586           AI156509.1         146-449
            1587-2018           AK165463.1         1553-1984
FEATURES             Location/Qualifiers
     source          1..2018
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 32.14 cM"
     gene            1..2018
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /note="threonine synthase-like 2 (bacterial)"
                     /db_xref="GeneID:232078"
                     /db_xref="MGI:MGI:3041254"
     exon            1..90
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            91..325
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..1554
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /product="threonine synthase-like 2"
                     /protein_id="NP_001029101.1"
                     /db_xref="CCDS:CCDS20225.1"
                     /db_xref="GeneID:232078"
                     /db_xref="MGI:MGI:3041254"
                     /translation="MWYTSTRGMAPRVNFEGALFSGYAPDGGLYMPEELPRLDEETLR
                     HWSTLSYRSLVKELCALFIGLELIPRHDLNDLIDRAFSRFRHRNVVHLCKLKNGLNIL
                     ELWHGVTYAFKDLSLSCTAQFLQYFLEKKKKHVTIVVGTSGDTGSAAIESVQGSKNVD
                     IIVLLPKGHCSKIQELQMTTVLKENVHVFEVEGNSDELDEPIKAVFADVAFVQRHNVM
                     SLNSINWSRVLVQMAHHFFAYFQCTPSLDTHPLPTVEVVVPTGAGGNLAAGCIAQKMG
                     LPICLVVAVNRNDIIHRTVQKGDFSLCEVLRTTLASAMDIQVPYNMERIFWLLSGSDS
                     QTTRALMEQFERTQSLQLPKDLHNKLSEAVTSESVTDEAITQTMARCWEENQYLLCPH
                     SATAVNYHYQQTDSGQSSIRCCLASASAVKFPEAVQAAGLTPETPAEILALEHKETRC
                     IPMRRGDDWTQMLRVTIEGLSQRWKDCVVNPSE"
     exon            326..520
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            521..673
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            674..904
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1053
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1179
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1331
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..2018
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1767..1772
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /note="hexamer: ATTAAA"
     polyA_site      1786
                     /gene="Thnsl2"
                     /gene_synonym="TSH2"
                     /note="major polyA site"
ORIGIN      
        1 ctttaaactc agaacctccg gctcagggaa gtcagagctg tgcgcgtcgc ccactggact
       61 cgggtctcca ggcagctccg cgcccctacg ggctccagga ccatgtggta cactagcacc
      121 cggggaatgg ccccacgggt caactttgag ggggccctct tctctggtta tgcaccagat
      181 gggggcctct atatgccaga ggagctccct aggctggacg aagagaccct gcgtcactgg
      241 agcacgctgt cctatcgcag cctggtgaag gagctgtgtg ctctcttcat tggtctggag
      301 cttattccaa gacatgactt aaatgatctg attgaccgag ccttcagcag attccgccac
      361 agaaatgtgg tccatctatg caagctgaag aatggactga acatactgga gttgtggcat
      421 ggggtcacat atgcctttaa ggacctgtcc ctgtcctgca cagcacagtt cctgcagtac
      481 ttcctggaga agaagaagaa gcatgtcacc attgttgtgg gaacttctgg ggacacggga
      541 agtgctgcca ttgagagtgt tcaaggatcc aagaatgtgg acattattgt tctgttgccc
      601 aaaggccatt gctcaaagat ccaggagctc cagatgacaa cggtgttaaa ggagaacgtt
      661 catgtgtttg aagtggaagg aaacagcgat gagcttgacg aacccatcaa ggccgtgttt
      721 gctgatgtgg cctttgtcca gaggcacaat gtgatgagct tgaactccat caactggtct
      781 cgggtcctgg tgcagatggc acaccacttc ttcgcttatt tccagtgtac accatccttg
      841 gatacgcacc ccctgcccac agtggaggtg gtagtgccga cgggagctgg gggtaacctt
      901 gcagctgggt gcattgctca gaagatgggc ctgcctatct gtctggttgt ggcagtgaac
      961 cgcaacgaca tcattcacag gactgtccag aagggagact tctctctgtg tgaggttctc
     1021 agaacaaccc tggcatctgc tatggacatt caggttccct acaacatgga gaggatcttc
     1081 tggctgctct ctggctctga cagccagaca acaagagccc tcatggaaca gtttgaaaga
     1141 acccaaagtc tgcagctacc caaggaccta cataacaagc tttcagaggc agtgacatct
     1201 gagtctgtga ctgatgaggc catcacccag actatggccc gctgctggga ggaaaaccag
     1261 tacctactgt gcccccactc ggccacagcg gtgaactacc attaccagca gactgacagt
     1321 ggacagtcca gcatcaggtg ctgcctggcc tctgcctcag cagtcaaatt cccagaagca
     1381 gtccaggcgg ctgggctgac cccagagact cccgcagaga tcctggccct ggagcacaag
     1441 gagacacgct gtatcccaat gcggagagga gatgactgga cacagatgct gcgggtcacc
     1501 attgagggcc tgtcccagcg gtggaaagat tgtgtagtga acccctcaga atagccaggc
     1561 tggaatggga ttgaagactc ttgtcccagg gctggctggg acaagatgtc tcagtagtta
     1621 ggaactcttg ctgctcttcc aggggaccca aatttagttc ccagtgccca tgtcaggtgg
     1681 ctcacaacca tctataactt cagctgtagg attttgacac ctctgtaggc agtgtacttg
     1741 tacacagata cacataccaa tatgtgatta aaaatgataa aggtaaggtg ggtgttttgt
     1801 tttgttttgt tttgttttgt tttgtttttt agtttcttgt tccagctgga tgtggtagca
     1861 catgccttta attccagcat tcaggaggaa gagacagaca ggtctctgca agttctaggc
     1921 cagcctggtc tatatagaaa gttccatggt aaatttgtgt ctttaaaact ctgtatactc
     1981 ttgtcccaag gagatgtgcc cttgcttctg gggaaagc
//
