LOCUS       NM_025920               2160 bp    mRNA    linear   ROD 11-JUN-2024
DEFINITION  Mus musculus THAP domain containing 4 (Thap4), transcript variant
            1, mRNA.
ACCESSION   NM_025920
VERSION     NM_025920.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Katayama,K., Ito,J., Murakami,R., Yamashita,A., Sasajima,H.,
            Narahashi,S., Chiba,J., Yamamoto,I., Fujii,W., Tochigi,Y. and
            Suzuki,H.
  TITLE     Mutation of the Thap4 gene causes dwarfism and testicular anomalies
            in rats and mice
  JOURNAL   Mamm Genome 35 (2), 149-159 (2024)
   PUBMED   38658415
  REMARK    GeneRIF: Mutation of the Thap4 gene causes dwarfism and testicular
            anomalies in rats and mice.
REFERENCE   2  (bases 1 to 2160)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   3  (bases 1 to 2160)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2160)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC066042.1 and AK167814.1.
            
            On Nov 4, 2005 this sequence version replaced NM_025920.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167814.1, BC063758.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-241               BC066042.1         27-267
            242-2160            AK167814.1         2-1920
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 47.29 cM"
     gene            1..2160
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /note="THAP domain containing 4"
                     /db_xref="GeneID:67026"
                     /db_xref="MGI:MGI:1914276"
     exon            1..382
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..2015
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /note="isoform 1 is encoded by transcript variant 1; THAP
                     domain-containing protein 4; peroxynitrite isomerase
                     THAP4; ferric nitrobindin"
                     /codon_start=1
                     /product="peroxynitrite isomerase THAP4 isoform 1"
                     /protein_id="NP_080196.3"
                     /db_xref="CCDS:CCDS15194.1"
                     /db_xref="GeneID:67026"
                     /db_xref="MGI:MGI:1914276"
                     /translation="MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQR
                     DNWTPTKYSFLCSEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLSEKKRGAGGHGHARR
                     KTTAAMRGHTSAETGKGTIGSSLSSSDNLMAKPESRKLKRASPQDDAAPKVTPGAVSQ
                     EQGQSLEKTPGDDPAAPLARGQEEAQASATEADHQKASSSTDAEGADKSGISMDDFTP
                     PGSGACKFIGSLHSYSFSSKHTRERPSVPREPMDRKRLKREMEPRCSGNSVAQSPPSS
                     SLTATPQKASQSPSAPPTDVTPKPAAEAVQSEHSDASPMSINEVILSASGACKLIDSL
                     HSYCFSARQNKSQVCCLREQVEKKNGELKSLRQKVSRSDSQVRKLREKLDELRRASLP
                     YLPYLSGLLPPSHEPPKLNPVVEPLSWMLGTWLSDPPGVGTFPTLQPFQYLEEVHISH
                     VGQPMLNFSFNSFHPETHKPMHRECGFIRLKPDTNKVAFVSAQNTGIVEVEEGEVNGQ
                     ELCVSSHSVSRISFAKEPHVEQITRKFRLNSEGKLEQTVSMATTTQPMTQHLHITYKK
                     VTP"
     exon            383..1521
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1681
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1791
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..1895
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..2160
                     /gene="Thap4"
                     /gene_synonym="2010320B01Rik; Nb(III)"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgcttcgg aacacccggg agccggcccg agctgcgctc ctccggcgcc gccatctttc
       61 cgtacagaca gccacccgcg catgtctcgg tacggactca ccgcccgctg cggccgcgac
      121 gccggcgccg tggccgggca gtccgagcgc agcgtggtgc gggcggcagc gcgcagccat
      181 cttgccgtac ggctcggccg cggcccacgt cccgagctgt gtcgccgcgc tccctcgggg
      241 cgggtcgggc cagcgggcgg gcggcaagga tcggagcctg gcggcgctca cgaccgaggc
      301 ccgcaatggt gatctgctgc gcggccgtga actgttccaa caggcagggc aagggcgaga
      361 aacgcgctgt ctccttccac aggtttcccc taaaggactc caaacgactg atccagtggt
      421 taaaagctgt tcagagggat aattggaccc cgactaagta ttcattcctc tgtagtgagc
      481 attttaccaa agacagcttc tccaaaagac tggaggacca gcatcgcctg ctgaagccca
      541 cggctgtacc ctctattttc cacctgtcag agaagaagag gggggctgga ggacatggcc
      601 atgctaggag aaagaccaca gcggccatga ggggccacac aagcgcagag acagggaaag
      661 gaaccatagg atcttcactg tcttcaagtg ataacttgat ggccaagcca gagtcccgaa
      721 agttgaagcg agcttctcca caagatgatg cagcccccaa ggtcacccca ggtgctgtca
      781 gccaggagca gggtcagtct ctggaaaaaa ctccaggaga tgacccggct gccccattgg
      841 ccagaggcca ggaagaggca caagcgtctg ctacagaggc tgaccaccag aaggcctctt
      901 cctccaccga cgctgagggg gcagacaaga gcggcatttc tatggacgac ttcacacctc
      961 cgggatctgg agcttgcaag ttcattggct cacttcattc atatagtttc tcctccaagc
     1021 acacgcgaga gaggccgtct gtccctcgtg agcccatgga ccgaaagagg ctgaagagag
     1081 agatggagcc aaggtgcagt gggaatagtg tggcccagag tcccccaagt tcctcactta
     1141 cagcaacccc tcaaaaggct tcccagagcc cctccgcccc tccaactgat gtaaccccta
     1201 agccagcagc agaagccgtg cagagtgagc atagtgatgc cagtcccatg tccatcaacg
     1261 aggtcattct gtcggcctcg ggggcctgca agctcatcga ctccctgcac tcctactgct
     1321 tctccgctcg gcagaacaag agccaggtat gctgcctgcg ggagcaggtt gagaagaaga
     1381 atggagagct aaagagcctt cggcagaagg tcagccgatc tgacagccag gtgcgcaagc
     1441 tgcgggagaa gctggacgag ctgaggagag cgagtctccc ctacctcccc tacctaagtg
     1501 gcctgctgcc ccccagccac gagcctccca agctgaatcc agtggtggag ccgttgtcct
     1561 ggatgctggg tacctggctg tcagacccgc caggagttgg tacctttccg acactgcagc
     1621 ccttccagta cctggaggag gtgcacatct cccacgtggg tcagcctatg ctcaacttct
     1681 cgttcaactc cttccatcca gaaacacaca agccaatgca cagagagtgt ggcttcatcc
     1741 gcctcaagcc tgacaccaac aaagtggcct ttgtcagtgc ccagaacaca gggattgtgg
     1801 aagtggagga gggtgaagtg aatgggcagg agctgtgtgt ctcatcccat tccgtctcca
     1861 ggatctcctt tgccaaggag ccccatgtgg agcagatcac tcggaaattc aggctgaatt
     1921 ctgaaggcaa acttgaacag acggtctcta tggcaaccac tacacagcca atgactcaac
     1981 atcttcacat tacctacaag aaggtgaccc cttaacctgg agccactccc agagcctgtt
     2041 tggtagacat ggtgtggtca caggctctgc tgacactgaa gtgttgtcca ggtgttcttg
     2101 taatggcata gaaaaccaaa taaaaggcct ttatttttat ggctgaagat tttgaatatt
//
