LOCUS       NM_025780               4982 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus THAP domain containing, apoptosis associated protein 2
            (Thap2), mRNA.
ACCESSION   NM_025780
VERSION     NM_025780.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4982)
  AUTHORS   Phillips,R.L., Ernst,R.E., Brunk,B., Ivanova,N., Mahan,M.A.,
            Deanehan,J.K., Moore,K.A., Overton,G.C. and Lemischka,I.R.
  TITLE     The genetic program of hematopoietic stem cells
  JOURNAL   Science 288 (5471), 1635-1640 (2000)
   PUBMED   10834841
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK081303.1, AK051198.1, BU698918.1, BG073155.2 and CX208940.1.
            
            On Jul 21, 2016 this sequence version replaced NM_025780.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.117424.1, AK081303.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1311              AK081303.1         2-1312
            1312-2670           AK051198.1         1092-2450
            2671-3018           AK081303.1         2674-3021
            3019-3794           AK051198.1         2799-3574
            3795-4309           BU698918.1         2-516
            4310-4863           BG073155.2         112-665             c
            4864-4982           CX208940.1         331-449
FEATURES             Location/Qualifiers
     source          1..4982
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 63.51 cM"
     gene            1..4982
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /note="THAP domain containing, apoptosis associated
                     protein 2"
                     /db_xref="GeneID:66816"
                     /db_xref="MGI:MGI:1914066"
     exon            1..231
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..814
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /codon_start=1
                     /product="THAP domain-containing protein 2"
                     /protein_id="NP_080056.1"
                     /db_xref="CCDS:CCDS24179.1"
                     /db_xref="GeneID:66816"
                     /db_xref="MGI:MGI:1914066"
                     /translation="MPTNCAAAGCAATYNKHINISFHRFPLDPKRRKEWVRLVRRKNF
                     VPGKHTFLCSKHFEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSLKLKSRNLLKTNNS
                     FPPTGPCNLKLNGSQQVLLEHSYAFRNPMEAKKRIIKLEKEIASLRKKMKTCLQRERR
                     ATRRWIKATCFVKSLEASNMLPKGISEQILPTALSNLPLEDLKSLEQDQQDKTVPIL"
     exon            232..427
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            428..4976
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1193..1198
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1214
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
     regulatory      4953..4958
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4976
                     /gene="Thap2"
                     /gene_synonym="2900040O07Rik; 9030625G08Rik"
                     /note="major polyA site"
ORIGIN      
        1 accccggtac tgtgcacgcc cctctgccct ccccgcgctc tgcaccgagc tggcggcgcg
       61 gggtcgcctg cctcgtttgt ctagcgtttg acagaagctt gcttagcggg cagcgcctcc
      121 gaagtggcgt aaggtggcgc cgaatgaggg gcccggggaa atgccgacca attgcgccgc
      181 ggcgggctgt gctgctacct acaacaagca cattaacatc agcttccaca ggtttccttt
      241 ggatcctaaa agaagaaaag aatgggttcg cctggttagg cgcaaaaatt ttgtgccagg
      301 aaaacacact tttctttgct caaagcactt tgaagcctcc tgttttgatc taacaggaca
      361 aacccgacga cttaaaatgg atgctgttcc aaccattttt gatttttgta cccatataaa
      421 gtctctgaaa ctcaagtcaa ggaatcttct gaagacaaac aacagttttc ctccaactgg
      481 accatgtaat ttaaagctga acggcagtca gcaagtactg cttgaacaca gttatgcctt
      541 taggaaccct atggaggcga aaaaaaggat aattaaacta gaaaaggaaa tagcaagctt
      601 gagaaaaaaa atgaaaactt gcctgcaaag agaacgcaga gcaactcgaa ggtggatcaa
      661 agccacgtgc tttgtgaaga gcttagaagc aagtaacatg ctacctaagg gcatctcaga
      721 acagatttta ccaactgcct taagcaatct tcctctggaa gatttaaaaa gtcttgaaca
      781 agatcaacaa gataaaacag tacccattct ctaaatgtaa aatggaagag actctctgca
      841 ctcaagtttt cctcacacag aacccagtgc ccagctcctg ccgtccccac ccaccgcact
      901 ctgacagtta cactacaatc aagtcctgca gttttacttg aagtagtagt gtcagtgtca
      961 ctctctggag actgaggaag tgggaaatcc aatgacaagc ttgacaccga gcagaagtgc
     1021 cttacatgag ggtcacggac ttaggaaaca ctgccagcag ggtttctgct cttgtttttt
     1081 taagctgctg tcaaatagga atgacaagtg atatgttcat aaaagtaaaa gcattccgca
     1141 ccaaagctgg gatattacat tctaaagaac atgtgaagta ggagctaact gcattaaata
     1201 tgatcttaaa actactaatg tattttgtat gaattaaatt attgggattg tggttgaaaa
     1261 ttttatagaa taaaacctct ggggtacggg gcaaggtttg tttctttgtt ttgttttgtt
     1321 ttttgtcttt tttagccttt tgtattttaa ctagtaaaag taaacttatc atggcctttt
     1381 tttataagaa cattgaattt aaaagtaggt tgtaaaataa tctgaaatag tattttgaat
     1441 gtgaaatacc tttgaaactc caaactaggt aaggccccaa gcacctcaga ctgggaaaac
     1501 ccagtgagtt atagtcaacg tctaagaaaa tatacagaaa agaatgcaga attggaagtc
     1561 tagcttttac cctaacaaaa caaatagaca aaggtacatt atttttttct cttataataa
     1621 agattttgaa tctccatctt cataattgat atgttaataa acactttaga cccatttgtt
     1681 cctcgcattg atagcaaaat cttttttttt tttggtcctt cccccccacc ccccagacag
     1741 ggtttctctg tgtagtcgtg gctgtcctgg aactcactct gtagaccaga ctggcctcga
     1801 actcagagat ccgcctgcct ctgcctccca agtactgaga ttaatggcgt gcaccatcat
     1861 gaccactgcc tgacttgaca gcaaattctt aaactgatct ttcttttttg tgacgacttc
     1921 tgcctcccaa gtgctgggat taaaggcgtg tgccaccacc gcccggctgt gactacttct
     1981 taattacctt tttttaatgt caaaaatagc ttttccctcc ttaataaatc acagaataat
     2041 ttaatcccaa ggaactacat aactatattg tatttcagac ccaggtctgg ctgctgcata
     2101 tccatgtctg aggatgggaa agcttctaag aaagtgtctg aggatctaag aaggtgtttt
     2161 aaggttggga agttcagcat agagggcggg gtatggcatc catgccctgt accaggtagg
     2221 gcctggggga gctgagagga cctggagccc aggtccactt tggtacgcta actatgcacc
     2281 tccgccactt gtcctgggtg tgaaacccaa tagtgtcaag ttaaaacagg ctcagtttat
     2341 cttactccat cagcttgctt tttaacccct cccccccctt tttttggata attgaaacaa
     2401 ctttaattca taatggaaat aaaatacagt cctctaaaat aatgtgtgtc tctgtgataa
     2461 agctatgcaa atgctgatat ttataaaata gaaatagcaa aatcgctctt ctggaaccac
     2521 ttgcaccttg aaaaggcctt gtgtcactaa aagtctaata agagccctcc cttcaaaata
     2581 agagcccttc cttcaaaaag ctgtggctaa gtaagtaaaa gtgtattcac ataagttatg
     2641 tagttcttct tcaagtttgt gagcttacca tatgaacata acatgcctga tcacacgtga
     2701 ctgtaaacct ttcctacaca gagatggaat ttgaattctc tgccatctct tgggctgttc
     2761 ctctctgtcc cacccagcaa ccagcactgt ctagtaagaa ttgtcttccc tgcaaacata
     2821 agggtgggaa atggctctct tagttttcat gtgatactta tgaccaatac tctataaact
     2881 cttttgtaga tgtgatcacc cttggtagct atcttaagta ttgggtaaag ttccttaaat
     2941 ttgtcattgt atattttttc ctaatactgg ttcatgtgtc tttatattat ctcaaatatc
     3001 cacggcaaat acactgagtg tacctacttg atagcctaaa ataagctggg taactaatcg
     3061 tattaacata acctatgctc ttgaaatgta aactttcata tggtttacca tgttccccaa
     3121 gccccaacca ctaattcatg tggtctgcct agggtttgta tcttgatatc ttaatacatt
     3181 tttttttaaa tcataaatgt acagcattgt aaaatacaag cacttttggc aaagttgcat
     3241 agtcttcatt cagtatcatc agcctttagt ttctttgggc tgtgttgttt gtgtgctgga
     3301 aattgaaccc agggcttcac gcatgcatgt atacgctccc acggagccac atccccagtc
     3361 tttttcattc actatttgtg gacaccattg aataaaccat cctctcagta aatgtaattc
     3421 tctgcctgtt ttcttcatgt tattttccca atagcatgct gcaaagcctc tttacatgac
     3481 tgtatcaata acacatctgt ccacctttaa aatggctgcc tagctaacac acatctgtca
     3541 cggtagccac gagggagaag gaagtgaagg tggggaagca ggagttccag gcttttaaaa
     3601 acattcaagg aatcctacaa tcctgccttc agtgtgctga tagatttatt tagttgactg
     3661 taaaccagaa aactgatgga gtgaggcctg atgaagccag aggacaaatg cctctaattc
     3721 ctgtgctttg gaggaatagt gggagggccc aaaactcaaa tagccagctt aggctatttg
     3781 agaccttgtt aggaaaataa acaaacctgt cagaattaca acagtaatat ctgagtcaga
     3841 cctcacagat cttctatctg tccagtttgt ctacacgcta ctaacattca caaagcaaaa
     3901 cgaaaaaaca aaaacacagc tgaaggttag gaatttgata taaagacaaa tactagactg
     3961 ggagatgtgt cctgttcagc atgcatcaag cccaaggttc aaactccaac acccaaaagg
     4021 ggttaaatac aacactggct acccttcggt tgctgcaagc ctcccaaaag aacggtgctt
     4081 attagaatat gagatgcatt ctatgaacga aataggtgta agatgcttcg gtacacgctg
     4141 ttgagttgaa actcaatgga aagcgtcgaa actttagact tatttacaac caagtgactt
     4201 ccttttgaaa tcaaacggat ttttcttaga atggctggtg agaggtgggc agagttctag
     4261 ggtttgacct gagttcagtg ttactgggtc agaatcctta aaaaaaaaaa acaacaacaa
     4321 caacaaaaaa aaaaccctac actgaacaga tcgaaatgat tgctgaaaga aagacacagc
     4381 tagaagtagg tcaaagctga gaacgggaat atttgaaact tgatattttg gaaacacata
     4441 accctattga taggtttctg agcaaaatca tgaaacagtt gttttccgat ctctgccttc
     4501 ctccttccaa gctggattta cacgagaaga tctctttgtt tactcggtca cacatgactg
     4561 tcccacttgc aaagagatgg agatgtctgc ggtccacgca gtgctaggac gaacatgtgt
     4621 cttccagttc tcctcctttc aatgtatgtt atcaaaatag gggaaaaaaa tcatgtgttt
     4681 tagaaaagca aaagataaac tttaaatgta ttaaagatat ttatgagatc cttgctaatg
     4741 gtgtctatgg agattttgtt atgttctctc acttctcagt gttagaatac gggtaaattt
     4801 taattttgat ataatagaga agctaatctt atatcaggag tgggattctt ttgatattta
     4861 gacagttgaa tactttataa aattaacaat tttgtaatgt atatgaaaca ataacactgt
     4921 actcattaag aaatgtattt gaatttgtta ctattaaaaa attgtttccc aaggaaaaaa
     4981 aa
//
