LOCUS       NM_027919               1840 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus threonine aldolase 1 (Tha1), mRNA.
ACCESSION   NM_027919
VERSION     NM_027919.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1840)
  AUTHORS   Edgar AJ.
  TITLE     Mice have a transcribed L-threonine aldolase/GLY1 gene, but the
            human GLY1 gene is a non-processed pseudogene
  JOURNAL   BMC Genomics 6, 32 (2005)
   PUBMED   15757516
  REMARK    GeneRIF: Mice, the western-clawed frog and the zebrafish have
            transcribed threonine aldolase/GLY1 genes, but the human homolog is
            a non-transcribed pseudogene
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591433.6.
            
            [WARNING] On May 8, 2024 this sequence was replaced by NM_027919.5.
            
            On Nov 20, 2008 this sequence version replaced NM_027919.3.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data because no single transcript from the reference genome strain
            was available for the full length of the gene. The extent of this
            transcript is supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY219871.1, BC055825.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-356               AL591433.6         49514-49869         c
            357-440             AL591433.6         47947-48030         c
            441-529             AL591433.6         47355-47443         c
            530-715             AL591433.6         46778-46963         c
            716-853             AL591433.6         46014-46151         c
            854-1046            AL591433.6         45703-45895         c
            1047-1840           AL591433.6         44292-45085         c
FEATURES             Location/Qualifiers
     source          1..1840
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 82.96 cM"
     gene            1..1840
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /note="threonine aldolase 1"
                     /db_xref="GeneID:71776"
                     /db_xref="MGI:MGI:1919026"
     exon            1..356
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1330
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /codon_start=1
                     /product="threonine aldolase 1"
                     /protein_id="NP_082195.2"
                     /db_xref="CCDS:CCDS48993.1"
                     /db_xref="GeneID:71776"
                     /db_xref="MGI:MGI:1919026"
                     /translation="MLCSLFRAAMLRSLFRATVPGLRVPWAQWSRNWAGVPAHVVDLR
                     SDTVTRPGPAMRRAMAEAVVGDDDYGEDPTVHELQEKAAELLGVERTLFVPTNTMANL
                     ISVMGHCRRRGSQVLLGQECHLHVYEQGGVAQIAGVHSHPLPDLPYGTLDLNELERAL
                     TRGSGSPYHPVCELVYLENTHSSAGGRVLPVDYLRQVCLLAHAHGARVHMDGARLMNA
                     AVALRIPPARLVEHCDSVSFCFSKGLGAPVGALVGGSKDFIGEAWRLRKALGGGMRQA
                     GVLAAAALVGLAEAEEVLPRDHENAQRFAKGLQDLASPICSVDPATVETNMVLVQVAG
                     LPPSELCQRLQAVSAEEVAQTGRAVRVLLFPWTEQSVRAVWHRDVSAQDTELALKKWE
                     FVLRQLRP"
     exon            357..440
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     exon            441..529
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     exon            530..715
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     exon            716..853
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1046
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1840
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1822..1827
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
     polyA_site      1838
                     /gene="Tha1"
                     /gene_synonym="1300017K07Rik; GLY1"
ORIGIN      
        1 atagtgcccc gggcttgccc agttcaggtc cgcgcggggt cagaagagtc cagttacacg
       61 ggttccccgc tggcacggaa gagactgtcc tccgctcctg cggccgagaa agacgagtgc
      121 cacagccatg ctatgcagcc tgttccgggc cgccatgcta cgcagcctgt tccgggccac
      181 ggtcccgggg ctcagggtgc cctgggctca gtggtctagg aattgggcgg gggtcccagc
      241 ccacgtggtg gacctacgca gcgacacggt gacccggcca gggccggcca tgaggcgcgc
      301 tatggccgaa gcggttgtag gagacgatga ttacggcgaa gaccctacgg tccacgaact
      361 gcaggaaaag gctgcagagt tgcttggggt agagaggacg ctgtttgtgc ccaccaacac
      421 tatggccaac ctcatctctg tgatgggtca ctgccggcgc cggggttccc aggtcctcct
      481 tgggcaggaa tgccacctcc acgtctatga gcagggcggg gtggcacaga tcgctggggt
      541 gcattcccac cccctccccg acctgcccta tggcaccttg gacctgaatg agctagagag
      601 ggcactcacg cggggctctg ggagtcccta ccatccagtc tgtgagctcg tgtacctgga
      661 gaacactcac agcagcgcgg gaggccgggt cctccctgtc gactacctcc gccaggtgtg
      721 cctcctggcc cacgcccacg gagcaagggt ccacatggat ggagctcggt tgatgaatgc
      781 agcagtggct ctgcgcatac cccctgcccg ccttgtagag cactgtgact ctgtatcctt
      841 ctgtttctct aagggcctag gtgcaccagt gggagctctg gttggcggat ccaaagactt
      901 cattggagaa gcatggcgcc tccgcaaggc cctgggtgga ggcatgcgcc aggctggagt
      961 gctggctgcg gctgccctgg tgggactagc tgaggcagag gaggtgctac caagggacca
     1021 cgagaatgcc cagagattcg ctaaaggact ccaagacctg gcgtcaccca tttgctctgt
     1081 ggatcctgcc accgtggaga ccaacatggt gctggtgcag gtagctgggc tgcctccctc
     1141 ggagctatgc cagcgcctgc aggctgtgag tgcagaggag gtggctcaga ctggccgtgc
     1201 cgtgcgcgtg ctgctgtttc cctggacaga acagtctgtg cgggctgtgt ggcaccgaga
     1261 tgtgtctgct caggacacgg aactggcact gaagaagtgg gagtttgtgc tgagacagtt
     1321 gcggccctga ggccagggga tccgggaccc cgtgctacga ttggagtggg cagtgagatg
     1381 cctgaagctg ttagcctggt gaaggctcat cctctctgga ggatggtgac atcattccgt
     1441 ctctggtttg ctccagtgac actcctggga tggccttacg cagtcaggaa taaccaggca
     1501 taaggtgggg aaagctgtga ctgcatatcc agagaaggaa gcgcatagag gaggcaggcc
     1561 ctggggttgg ggttggccct ggggtgtagc aggattgcct agtgtgcata agccctgggc
     1621 tccatcccca gcactgtggg ttcgaacccc agcagctcac agctcacaac tgtaacccta
     1681 ccatgctagg ggattagaag ctcaaggcca ctctcagcta ctcagagaat ttgatgcaag
     1741 cctgggctac acgagaccct gtcttcaaga aaatagatcc ttagtgactg acacagtgga
     1801 gttgtcagag gtggactgtg aaataaaata ctgaaggcac
//
