LOCUS       NM_009443               5025 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus trans-golgi network protein (Tgoln1), mRNA.
ACCESSION   NM_009443 XM_001471627 XM_001471628
VERSION     NM_009443.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5025)
  AUTHORS   Hara,Y., Katsuyama,T., Fukaya,M., Sugawara,T., Shiroshima,T.,
            Sadakata,T., Osumi,N. and Sakagami,H.
  TITLE     ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through
            N-Cadherin Trafficking during Cerebral Cortical Development
  JOURNAL   eNeuro 10 (11) (2023)
   PUBMED   37848288
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5025)
  AUTHORS   Mills,J., Hanada,T., Hase,Y., Liscum,L. and Chishti,A.H.
  TITLE     LDL receptor related protein 1 requires the I3 domain of
            discs-large homolog 1/DLG1 for interaction with the kinesin motor
            protein KIF13B
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1866 (12), 118552 (2019)
   PUBMED   31487503
REFERENCE   3  (bases 1 to 5025)
  AUTHORS   Zhang,D., Marlin,M.C., Liang,Z., Ahmad,M., Ashpole,N.M.,
            Sonntag,W.E., Zhao,Z.J. and Li,G.
  TITLE     The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and
            Signal Transduction of Tropomyosin Receptor Kinase A
  JOURNAL   J Biol Chem 291 (46), 23895-23905 (2016)
   PUBMED   27655914
REFERENCE   4  (bases 1 to 5025)
  AUTHORS   Urresti,J., Ruiz-Meana,M., Coccia,E., Arevalo,J.C., Castellano,J.,
            Fernandez-Sanz,C., Galenkamp,K.M., Planells-Ferrer,L.,
            Moubarak,R.S., Llecha-Cano,N., Reix,S., Garcia-Dorado,D.,
            Barneda-Zahonero,B. and Comella,J.X.
  TITLE     Lifeguard Inhibits Fas Ligand-mediated Endoplasmic
            Reticulum-Calcium Release Mandatory for Apoptosis in Type II
            Apoptotic Cells
  JOURNAL   J Biol Chem 291 (3), 1221-1234 (2016)
   PUBMED   26582200
REFERENCE   5  (bases 1 to 5025)
  AUTHORS   Chen,L., Ge,Z.J., Wang,Z.B., Sun,T., Ouyang,Y.C., Sun,Q.Y. and
            Sun,Y.P.
  TITLE     TGN38 is required for the metaphase I/anaphase I transition and
            asymmetric cell division during mouse oocyte meiotic maturation
  JOURNAL   Cell Cycle 13 (17), 2723-2732 (2014)
   PUBMED   25486359
  REMARK    GeneRIF: TGN38 may regulate the metaphase I/anaphase I transition
            and asymmetric cell division in mouse oocytes.
REFERENCE   6  (bases 1 to 5025)
  AUTHORS   Urushitani,M., Sik,A., Sakurai,T., Nukina,N., Takahashi,R. and
            Julien,J.P.
  TITLE     Chromogranin-mediated secretion of mutant superoxide dismutase
            proteins linked to amyotrophic lateral sclerosis
  JOURNAL   Nat Neurosci 9 (1), 108-118 (2006)
   PUBMED   16369483
REFERENCE   7  (bases 1 to 5025)
  AUTHORS   Maric,J., Kiss,R.S., Franklin,V. and Marcel,Y.L.
  TITLE     Intracellular lipidation of newly synthesized apolipoprotein A-I in
            primary murine hepatocytes
  JOURNAL   J Biol Chem 280 (48), 39942-39949 (2005)
   PUBMED   16204232
REFERENCE   8  (bases 1 to 5025)
  AUTHORS   Steveson,T.C., Ciccotosto,G.D., Ma,X.M., Mueller,G.P., Mains,R.E.
            and Eipper,B.A.
  TITLE     Menkes protein contributes to the function of peptidylglycine
            alpha-amidating monooxygenase
  JOURNAL   Endocrinology 144 (1), 188-200 (2003)
   PUBMED   12488345
REFERENCE   9  (bases 1 to 5025)
  AUTHORS   Antony,C., Huchet,M., Changeux,J.P. and Cartaud,J.
  TITLE     Developmental regulation of membrane traffic organization during
            synaptogenesis in mouse diaphragm muscle
  JOURNAL   J Cell Biol 130 (4), 959-968 (1995)
   PUBMED   7642711
REFERENCE   10 (bases 1 to 5025)
  AUTHORS   Kasai,K., Takahashi,S., Murakami,K. and Nakayama,K.
  TITLE     Strain-specific presence of two TGN38 isoforms and absence of TGN41
            in mouse
  JOURNAL   J Biol Chem 270 (24), 14471-14476 (1995)
   PUBMED   7540170
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK076586.1 and AC125039.4.
            
            On or before Nov 25, 2008 this sequence version replaced
            XM_001471627.1, XM_001471628.1, NM_009443.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161242.1, SRR1660813.34145.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2970              AK076586.1         2-2971
            2971-5025           AC125039.4         83789-85843         c
FEATURES             Location/Qualifiers
     source          1..5025
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 32.27 cM"
     gene            1..5025
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="trans-golgi network protein"
                     /db_xref="GeneID:22134"
                     /db_xref="MGI:MGI:105080"
     exon            1..324
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /inference="alignment:Splign:2.1.0"
     CDS             279..1340
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="trans-Golgi network integral membrane protein 1;
                     trans-golgi network protein 1"
                     /codon_start=1
                     /product="trans-Golgi network integral membrane protein 1
                     precursor"
                     /protein_id="NP_033469.1"
                     /db_xref="CCDS:CCDS51811.1"
                     /db_xref="GeneID:22134"
                     /db_xref="MGI:MGI:105080"
                     /translation="MRFQVALLLLSVAVARALPSVYKRDADSGDSQNPPNQPSKQSST
                     PLPSSNQVKTTRPTDGQGQKSDKKDQDKTTLAAVSSKAESGPRTAATDHSLGDSRRQP
                     EKTDAELNETARPLSPVNPKLEKSDQSSTEDSGKPTGGNSGKPTGGDSGKPTEAGSNK
                     ATEDDSGKSTKVDLDKPTSKISPDTETSKTDKVQPTEKGQKPTLTSKTESGETLAGDS
                     DFSLKPEKGDKSSEPTEDVETKEIEEGDTEPEEGSPLEEENEKVPGPSSSENQEGTLT
                     DSMKNEKDDLYKDSSGNTSAESSHFFAYLVTAAVLVAVLYIAYHNKRKIIAFALEGKR
                     SKVTRRPKASDYQRLNLKL"
     exon            325..1250
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..1334
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..5025
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1907..1912
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="hexamer: AGTAAA"
     polyA_site      1942
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="major polyA site"
     polyA_site      1953
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
     regulatory      2952..2957
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="hexamer: AATAAA"
     polyA_site      2972
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
     regulatory      4997..5002
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="hexamer: AATAAA"
     polyA_site      5025
                     /gene="Tgoln1"
                     /gene_synonym="D6Ertd384e; TGN38; TGN38A; Ttgn1"
                     /note="major polyA site"
ORIGIN      
        1 agcttccgaa aaacgaggcc aagtgaacaa gaacgagatc gccgagcccc gcagactgct
       61 gagaaacaga agggacttgg gggggaataa agagctggac ttgacttccg gcactctacc
      121 ggaacacaca gacaacggct gctgtcgccc ggtagcccca cccctaaggc ggggctgcgc
      181 cggaagagaa acagtccgcc ggaaagggag gggccacgct cgggaaaatc tcgtgcgccg
      241 ctctcacgtc atcagagggc ggaagcgcag actgcaggat gcggttccag gttgcgttgc
      301 tcctgctgag tgtcgcggtg gcgagagctc tgccgtccgt ttataagaga gacgccgact
      361 caggtgactc tcagaatcct ccgaatcagc cttccaaaca gtcctccact cccctgcctt
      421 cttctaacca ggtaaagact acaaggccga ccgacggtca ggggcagaag tcagataaaa
      481 aagaccagga caagacgact ttggcagcag tttccagtaa ggcggaatct gggccgcgga
      541 ccgccgcgac cgatcacagt ttgggtgatt ccagaaggca gcccgagaaa acggatgccg
      601 agttgaacga aactgcgcgg cccctctcac cagtcaaccc caaactggaa aagtctgatc
      661 agagctccac agaagattca ggcaagccca caggaggtaa ttctggcaag cccacaggag
      721 gtgattctgg caagcccaca gaagctggtt cgaataaggc cacagaagat gattctggca
      781 agtccacgaa agttgatttg gacaagccca cctccaaaat ctccccagat acggagactt
      841 cgaagactga caaagtccag ccaactgaaa aaggacaaaa accaacactt acttccaaaa
      901 ctgaatctgg ggaaacactg gcaggggact ctgacttctc tttaaagcca gagaaaggag
      961 ataagtcttc agagcctact gaagacgtgg aaaccaagga gattgaagag ggtgacacag
     1021 agccggaaga aggctcacca cttgaagaag agaatgaaaa ggtgccgggc ccttcctcca
     1081 gtgagaacca agaggggaca cttacagact ctatgaagaa tgagaaggat gatctttata
     1141 aggacagttc tggaaacacc agtgcagaga gcagccactt ctttgcatat ctagtgaccg
     1201 ctgctgttct tgttgctgtc ctctatattg cttaccacaa caaacgaaag attattgctt
     1261 ttgctctgga agggaaaaga tccaaagtca ctcggaggcc aaaggccagt gactaccaac
     1321 gtttgaacct aaagctttga tctttacttt gtctgcaaga accgtgtcct ccctgctgat
     1381 ttgttcccaa tgaagagaaa tgaaaagact gtgacctcct ctggggtttg gtggcaagtc
     1441 tgggctggca gagatgggat agcttcaggt tttgcaccgg cactttgatg acactctcct
     1501 ctggtgatgt tttatttact tttgtgttcc ttgtatgctg acgtgttcca tcatcctttc
     1561 ttccttggag tgcaaacgga agaagcacat ggaaaaatgg atgtgaccaa aggaagaccc
     1621 caccttaggc aggccacaca atggaccacc tttccacagc ctctttatct ttgcaactct
     1681 aggcgcaaac tgtagagagg tgctttctag acaagatgta gatggttatg tgggatactg
     1741 atgggcagag atggggttga atacttattc tctacagaag gctcagctgc aaaccaaact
     1801 agcaggttaa agagtgttaa agtctggtcc atctgatagt ctgtatattt ctctgaaagt
     1861 ttgcatgcta gttgtactag cataaaaggg actcgaggct tctgaaagta aaatcactgt
     1921 ttgatgggat tttttaaaaa aatgatcatt gaacaagtgt gttcttgcat acattcaccc
     1981 caataggaac ttcctggaaa gggacaggtt catgctttgt ggaagaaaac acataggagg
     2041 gatttagtat gcaggaaaga ggttttctac aaattgagtt ttgcttttat tgcccgcagt
     2101 agatagatat ttagaaacta actgcattct tcacactcct ccttgctgtt taagatgtgc
     2161 agggaataag gaaaatcttt cctatcctgt catatctggt catgaaactg taggaaacta
     2221 aataggttcc ctgagataac tgaagatgtc ttggattatg ctgtgtctag cgttttattc
     2281 cagtctgtat ggttacgcct aaagagagaa aagtctcagc taatctcagg gatgcagaga
     2341 gaacgagaag aagaaaagta tgagtcctgt gctgttgggg aaatcagtct aaggaagcaa
     2401 tggtcttgga ggtcttttcc agtgctgact gcagcatggg cttgaaattg aagtatgtat
     2461 tcttggcagg tggcattcta gaaataaggc catggctact attgtctcag ctgtccacaa
     2521 gtctgttact tttttccaag cctttttcag tctcctttag cttttcctaa cacctcttta
     2581 gttccccact tccatttttt cttcctctct atagacctgt ttgtacatct ctgaatgaac
     2641 accttcctta tagcctgtat gcacgcccat acctatcctg ttctagttgg tgttgcttct
     2701 attgccttcc atcctcttcc tgacatttgc agggttgcct tggtctgatt tcctcctgtt
     2761 tctcaaggtt tactcagtta acagatcacc aaattcagca gctcattttc acagcttgta
     2821 acccttggta ataatgttgg atgccggggc ctatgcatgt tgacattctg gttgtctctt
     2881 gcaaattatc ctttgcctta tctcatgggg atggaggagg gtacccaggt ctctgttgct
     2941 ttgactgtct caataaatcc atccattctt tatcctctct gtgacgctca tgtttttttt
     3001 ggcctccttc ccaagaaccc agttctgcta aataactcag ccacgttgtc tgcttgtcac
     3061 acaaccagag tttctctctt gtatctatta cgtttctcta tctatccttc actttctcta
     3121 atcatctgaa aactccacac tataaactaa aaacattttt atcatcacag aagtccactt
     3181 tttttttttt aaagaaatta tctaggtata ctctccgcta atttttagga accagctgaa
     3241 ttgaccttac cagttttgga aacattgatc attccagaat gtgccccggt ctgaagcttc
     3301 tgtctgaggt tataatctag actacagatt cctccttggc tgcactgcga cactcactcc
     3361 gtctctgcct ctgccctcct cgtgtctttg tatcacagct tttcggggtt gctctatggt
     3421 taggctgtcc ccttcttcca gccttctcag gcccttgtgc ttggaatatg catagtggtc
     3481 cttccattcc acactgatag cttactgtca ctctcatctt ggaacttcag tgtgacatag
     3541 ttctgatgtt ctgtgatctc cccccaagaa aactaagctc tgagagacag ccattgtcat
     3601 tgttctatca gccagagacc ttaggggtca aatttcttgt tggaggtgta gctgaaactg
     3661 gggctcacat agctcttcct ggatactgtt tgctatgacc ttatacttgt tggcttttgc
     3721 tcttgaagga ccggaaggaa aattgatttt tagcaacaaa gattgacagt gagtggacag
     3781 acatgtgaag gattgccaga gtctcctcac cctcttttgg ctgctgacat gttccttgtg
     3841 ctgacagagt acagtagaat ttgtgttcac ttgagaagtt gcactgaagg aaatggttcc
     3901 caccaaagaa aagttctttt taggagtttt gttttgtttt gttttttgaa ggtagaatac
     3961 ttgaagcata tttgctagag tgtgtggcaa tggtccagct gaggtgtcta taccagggat
     4021 tgggttggca tgtaagaagc atatgaagtc tcaagtagca ctcttgtgga cttttctgag
     4081 cttgctctcc tcagtgtttg gctaaagggc aatttcttaa ggggaagctg cttgaggtat
     4141 aactgttaat agtttgtttt cctgctgtgg actaaagaag ccagctctgg acaacaacta
     4201 acaaaatgtg ctaacatgtt tcccctagaa acagagctct gtgcccttca gagttcctct
     4261 ggtagggatg cactttctct tttcttcggg gcatggtatg ctttgcacat atcatgagcc
     4321 gttcgaaagc agagaagggt gtgccaggcc ctgtaccata gtttctcaaa actgcttact
     4381 aggagggttc tgtttggcat tgccttaaga aagctgtaaa gagtcaggcg tggtgatgca
     4441 tgcctttaat cctagcactc aagagtcaga ggcagaagga tctctgagta tgaggccagc
     4501 ctagtctaga ataccaagtt taggcagcca aagttacaca atgatagctt gtctcaaaaa
     4561 aaaaaaaaaa aaaaaaagca gaaagctgta aagagatgtt gaaatttaaa tacatcaaga
     4621 tggctcagtt tgttttgttc cctgctcaga tgtgatacta agtattttag cttagaaact
     4681 gtgagtttgg atctcagctt gcatagcata gcaaactacc catgaagctg gcctcctcac
     4741 actgttagga atttaattca gactaccatg ttaagtgagt gaatgttgaa atttttttcc
     4801 ttgtcttgtg ttcccagtta gattgctact gttagccatg tttggtattg tcaccttttt
     4861 tgtaacttaa ctgtaatggc ttaattttat tttttttaaa gcttactgtg gtatagtaag
     4921 tatttttcag tatattttac tgagcttctg taaatggaat catagcatag tttcatgtca
     4981 ttattgaaca gaaatcaata aatttcagat atcaaagcat tgaaa
//
