LOCUS       NM_018783               3549 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus tuftelin interacting protein 11 (Tfip11), mRNA.
ACCESSION   NM_018783
VERSION     NM_018783.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3549)
  AUTHORS   Deutsch,D., Silverstein,N., Shilo,D., Lecht,S., Lazarovici,P. and
            Blumenfeld,A.
  TITLE     Biphasic influence of hypoxia on tuftelin expression in mouse
            mesenchymal C3H10T1/2 stem cells
  JOURNAL   Eur J Oral Sci 119 Suppl 1, 55-61 (2011)
   PUBMED   22243227
  REMARK    GeneRIF: a member of oxygen-sensitive genes and implicated in the
            adaptive mechanisms regulating mesenchymal stem cell function
REFERENCE   2  (bases 1 to 3549)
  AUTHORS   Tannukit,S., Crabb,T.L., Hertel,K.J., Wen,X., Jans,D.A. and
            Paine,M.L.
  TITLE     Identification of a novel nuclear localization signal and
            speckle-targeting sequence of tuftelin-interacting protein 11, a
            splicing factor involved in spliceosome disassembly
  JOURNAL   Biochem Biophys Res Commun 390 (3), 1044-1050 (2009)
   PUBMED   19857462
  REMARK    GeneRIF: These data help define the mechanism of nuclear/nuclear
            speckle localization of the splicing factor TFIP11, with
            implications for it's function.
REFERENCE   3  (bases 1 to 3549)
  AUTHORS   Wen,X., Tannukit,S. and Paine,M.L.
  TITLE     TFIP11 interacts with mDEAH9, an RNA helicase involved in
            spliceosome disassembly
  JOURNAL   Int J Mol Sci 9 (11), 2105-2113 (2008)
   PUBMED   19165350
REFERENCE   4  (bases 1 to 3549)
  AUTHORS   Desai,J., Shannon,M.E., Johnson,M.D., Ruff,D.W., Hughes,L.A.,
            Kerley,M.K., Carpenter,D.A., Johnson,D.K., Rinchik,E.M. and
            Culiat,C.T.
  TITLE     Nell1-deficient mice have reduced expression of extracellular
            matrix proteins causing cranial and vertebral defects
  JOURNAL   Hum Mol Genet 15 (8), 1329-1341 (2006)
   PUBMED   16537572
REFERENCE   5  (bases 1 to 3549)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3549)
  AUTHORS   Staiger,D., Allenbach,L., Salathia,N., Fiechter,V., Davis,S.J.,
            Millar,A.J., Chory,J. and Fankhauser,C.
  TITLE     The Arabidopsis SRR1 gene mediates phyB signaling and is required
            for normal circadian clock function
  JOURNAL   Genes Dev 17 (2), 256-268 (2003)
   PUBMED   12533513
REFERENCE   7  (bases 1 to 3549)
  AUTHORS   Suzuki,T., Li,W., Zhang,Q., Karim,A., Novak,E.K., Sviderskaya,E.V.,
            Hill,S.P., Bennett,D.C., Levin,A.V., Nieuwenhuis,H.K., Fong,C.T.,
            Castellan,C., Miterski,B., Swank,R.T. and Spritz,R.A.
  TITLE     Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human
            homolog of the mouse light-ear gene
  JOURNAL   Nat Genet 30 (3), 321-324 (2002)
   PUBMED   11836498
REFERENCE   8  (bases 1 to 3549)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   9  (bases 1 to 3549)
  AUTHORS   Paine,C.T., Paine,M.L., Luo,W., Okamoto,C.T., Lyngstadaas,S.P. and
            Snead,M.L.
  TITLE     A tuftelin-interacting protein (TIP39) localizes to the apical
            secretory pole of mouse ameloblasts
  JOURNAL   J Biol Chem 275 (29), 22284-22292 (2000)
   PUBMED   10806191
REFERENCE   10 (bases 1 to 3549)
  AUTHORS   Paine,C.T., Paine,M.L. and Snead,M.L.
  TITLE     Identification of tuftelin- and amelogenin-interacting proteins
            using the yeast two-hybrid system
  JOURNAL   Connect Tissue Res 38 (1-4), 257-67 (1998)
   PUBMED   11063033
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC123848.4.
            
            On Nov 17, 2006 this sequence version replaced NM_018783.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF290474.3, BC017682.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AC123848.4         88298-88402         c
            106-291             AC123848.4         87101-87286         c
            292-512             AC123848.4         86589-86809         c
            513-666             AC123848.4         85252-85405         c
            667-823             AC123848.4         84868-85024         c
            824-951             AC123848.4         83553-83680         c
            952-1104            AC123848.4         82751-82903         c
            1105-1632           AC123848.4         81280-81807         c
            1633-1739           AC123848.4         81090-81196         c
            1740-1908           AC123848.4         80286-80454         c
            1909-2152           AC123848.4         79668-79911         c
            2153-2295           AC123848.4         79056-79198         c
            2296-2461           AC123848.4         78591-78756         c
            2462-3549           AC123848.4         76698-77785         c
FEATURES             Location/Qualifiers
     source          1..3549
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 54.69 cM"
     gene            1..3549
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /note="tuftelin interacting protein 11"
                     /db_xref="GeneID:54723"
                     /db_xref="MGI:MGI:1930075"
     exon            1..105
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            106..291
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            292..512
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     CDS             301..2817
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /note="tuftelin-interacting protein 33;
                     tuftelin-interacting protein, 39 kD; STIP-1;
                     tuftelin-interacting protein 39; septin and
                     tuftelin-interacting protein 1"
                     /codon_start=1
                     /product="tuftelin-interacting protein 11"
                     /protein_id="NP_061253.2"
                     /db_xref="CCDS:CCDS19539.1"
                     /db_xref="GeneID:54723"
                     /db_xref="MGI:MGI:1930075"
                     /translation="MSLSHLYRDGEGHLDDDDDDERENFEITDWDLQNEFNPNRQRHW
                     QTKEEATYGVWAERDSDEERPSFGGKRARDYSAPVNFISAGLKKGAAEEADSEDSDAE
                     EKPVKQEDFPKDLGPKKLKTGGNFKPSQKGFSGGTKSFMDFGSWERHTKGIGQKLLQK
                     MGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQSLQDFPVADSEEEAEEE
                     FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRVSKKLTAPQKELSQVKVIDMTGRE
                     QKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEARMPGFALPELEHNLQLLIERTEQ
                     EIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECERRMQPHG
                     ADPLTLDECARIFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDGSYGT
                     QIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNVVAQWQPRNCEPMVDF
                     LDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEP
                     LYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGEL
                     VINPHQQHMDAFYWVMDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITK
                     WYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTER
                     RKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHE
                     GKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK"
     exon            513..666
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            667..823
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            824..951
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1104
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1632
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1739
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            1740..1908
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..2152
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2295
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2461
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     exon            2462..3549
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2843..2848
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /note="hexamer: AATAAA"
     polyA_site      2864
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /note="major polyA site"
     regulatory      3529..3534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /note="hexamer: AATAAA"
     polyA_site      3549
                     /gene="Tfip11"
                     /gene_synonym="2810002G02Rik; Srr1; TIP33; Tip39"
                     /note="major polyA site"
ORIGIN      
        1 tccgatgcgc cggtaaaggc cacatccggg tttgggctgg cgggaccctc gcagattcgg
       61 ggacgctggg cgaaggctgt gtggctctcg cggatgctga gcgaggagtg actgcaaagt
      121 ggcattcaga aagactgcaa ccttccagta ccgtagaagc cgttcaggga aggaaacctt
      181 cagtcccgtg gaaatagtat ttcagaaaat gctctgaagt ttccctggaa ctgcaaattg
      241 gctagataca acttttcctg gagaagtaaa aagaccaacc tggtttctga gtgactggcc
      301 atgtctctgt cccacttgta ccgggatggc gaaggccacc ttgatgatga cgatgacgat
      361 gagagggaga actttgagat caccgactgg gatctccaga atgagttcaa ccccaaccgg
      421 cagcgccatt ggcagaccaa agaggaggcc acctacgggg tgtgggcgga gcgagactcg
      481 gacgaggaga ggcccagctt tggaggcaaa agggcccgag actattctgc acctgtcaac
      541 ttcatcagtg cggggctcaa gaaaggggcg gctgaggaag cggactccga ggactctgat
      601 gctgaagaga agcctgttaa gcaggaggac ttcccgaagg atttaggacc aaagaagtta
      661 aagacgggtg gcaattttaa gcccagccag aaaggctttt caggaggaac caagtccttc
      721 atggactttg gcagctggga gagacacacg aaagggatcg ggcagaagct gctgcagaag
      781 atgggctacg tccctgggcg tggcctgggg aagaacgcac aggggatcat caaccccatc
      841 gaagccaaac agagaaaagg caagggagcc gtgggggcct atggctcgga gaggaccact
      901 cagtctctgc aggacttccc cgtggccgac tcggaagagg aggcagaaga ggagtttcag
      961 aaggagctga gccaatggag gaaagacccc agcgggagca agaagaagcc aaagtactct
     1021 tacaagactg tggaggagct gaaggccaag ggcagggtca gcaagaagct cacagcacct
     1081 cagaaggaac tgtctcaggt caaggtgatc gacatgacag gccgggagca gaaggtgtac
     1141 tacagctaca gccaaatcag ccacaagcac agcgtgcccg atgaaggggt gccattgctg
     1201 gcgcagctgc cccccacagc cggcaaggaa gccaggatgc cgggctttgc actgcctgag
     1261 ctggagcaca acctgcagct gctcattgag cgcacggagc aggagatcat ccagagcgac
     1321 cggcagctcc agtatgagcg ggacatggtg gtcagcctgt cacacgagct ggagaagacg
     1381 gccgaggttc ttgcacatga ggagcgtgtc atctctaacc tcagcaaggt gctggccctg
     1441 gtggaggaat gtgagcgccg catgcagccc catggcgccg accccctcac tctggatgag
     1501 tgtgcccgca tctttgagac actacaggac aagtattatg aggagtaccg cctggcggac
     1561 cgcgcagacc tcgctgtggc cattgtctac ccgctcgtga aggactactt taaggattgg
     1621 caccccctcg aggacggcag ctatggcacc cagatcatct ccaagtggaa gagcctcctg
     1681 gagaacgacc agctgctgtc tcacagcagc caggacctgt cctccgatgc cttccacagg
     1741 ctcatgtggg aggtctggat gcctttcgtt cggaatgtcg tcgcccagtg gcagccacgg
     1801 aactgtgagc cgatggtgga tttcctggac agctgggcac acatcatccc cgtgtggatc
     1861 ctggacaata tcctggacca gctcatcttc cctaagctgc agaaggaggt ggacaactgg
     1921 aaccccctga cagacaccgt tcccatccac tcgtggatcc acccgtggct gccgctcatg
     1981 caggcccgcc tggagccact ctactcccct gtgcgcagca agttgtccag cgcactgcag
     2041 aaatggcacc ccagcgacgc ctcagccaag ctcatcctgc agccctggaa agaggtcctc
     2101 acccctgggt cctgggaggc cttcatgctc aggaacatcg tgcccaagct gggcatgtgc
     2161 ctgggagagc ttgtcatcaa cccccaccag cagcacatgg acgccttcta ctgggtgatg
     2221 gactgggagg ggatgatctc cgtctccagc ctggtggggc tgctggagaa gcatttcttc
     2281 cccaagtggc tccaggtgct gtgctcctgg ctcagtaaca gtcccaatta cgaggagatc
     2341 accaagtggt acctgggctg gaagtctatg ttctcagacc aggtgctggc ccacccttct
     2401 gtcaaggaca agttcaacga agcgctcgac ataatgaaca gggctgtgtc ctccaatgtt
     2461 ggtgcctaca tgcagccggg tgcgagagag aacattgcct acctcaccca cacagagcgc
     2521 aggaaggact tccagtacga ggccatgcag gagcgccggg aggctgagaa catggcacag
     2581 agaggcatcg gtgtggccgc cagctccgtg cccatgaact ttaaggacct catcgagact
     2641 aaggcagagg agcacaacat tgtgttcatg cctgtcatcg gcaagcggca cgagggcaag
     2701 cagctctaca ccttcggccg catcgtcatc tacattgacc ggggtgtggt gtttgtgcag
     2761 ggcgagaaga cgtgggtgcc cacctccctg cagagcctca tcgacatggc caagtagaca
     2821 tcggccacac cagaccggtg tgaataaaca gcactgtaaa ccaagctgat gaataacgtc
     2881 tctatttggg agaccaggcc accagggcag gatgtgactc agtgtcccca gtcggcctgt
     2941 attcctggcc gggcaaagga tctggtgtgg tgtgcaccgt ggctcctggc ccaggtggag
     3001 agaactgtcc tgttactcca gctgagcgat ctgtagcttt cctgatgatc tccaggtcct
     3061 cacagtcctg gtagtcaggc tcttcctggg atgcccacag gtccccaggc agtccttcca
     3121 gcttcaatag tgggaaccag tggacagatg tatcattaaa ggtgtcagtg tactggggag
     3181 tctgcggcag tgggacctcc tccaggcctt tcagaatctg agcagagagg accagatacg
     3241 ggcattaggt acacccctct ctatcttcac ctggccaccc caccgtcctt ctgagaaata
     3301 agggatgggg gggttgtatt tcagcacttt tcagtcccat gccagtgaga ctgctgggct
     3361 cgccctaagg atgaaggcca ctggcacaca gtaggagagg caccagctgg ttgtgcttag
     3421 aaacatggac agtgtggctt tgcaccctca ccccggccca gctattctgt cagacacctt
     3481 tgcaatgtag gggtaatttt cctgcagaat cctcgccaac aacctacaaa taaaaacata
     3541 catacacaa
//
