LOCUS       NM_001413823            3191 bp    mRNA    linear   ROD 03-SEP-2024
DEFINITION  Mus musculus transcription factor Dp 1 (Tfdp1), transcript variant
            32, mRNA.
ACCESSION   NM_001413823
VERSION     NM_001413823.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3191)
  AUTHORS   Tran,N.T., Graf,R., Acevedo-Ochoa,E., Trombke,J., Weber,T.,
            Sommermann,T., Salomon,C., Kuhn,R., Rajewsky,K. and Chu,V.T.
  TITLE     In vivo CRISPR/Cas9-mediated screen reveals a critical function of
            TFDP1 and E2F4 transcription factors in hematopoiesis
  JOURNAL   Leukemia 38 (9), 2003-2015 (2024)
   PUBMED   39043964
  REMARK    GeneRIF: In vivo CRISPR/Cas9-mediated screen reveals a critical
            function of TFDP1 and E2F4 transcription factors in hematopoiesis.
REFERENCE   2  (bases 1 to 3191)
  AUTHORS   Wu,M. and Ye,M.
  TITLE     Transcription factor Dp-1 knockdown downregulates thymidine kinase
            1 expression to protect against proliferation and
            epithelial-mesenchymal transition in cervical cancer
  JOURNAL   Funct Integr Genomics 23 (4), 301 (2023)
   PUBMED   37715794
  REMARK    GeneRIF: Transcription factor Dp-1 knockdown downregulates
            thymidine kinase 1 expression to protect against proliferation and
            epithelial-mesenchymal transition in cervical cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3191)
  AUTHORS   Guo,T., Han,X., He,J., Feng,J., Jing,J., Janeckova,E., Lei,J.,
            Ho,T.V., Xu,J. and Chai,Y.
  TITLE     KDM6B interacts with TFDP1 to activate P53 signaling in regulating
            mouse palatogenesis
  JOURNAL   Elife 11, e74595 (2022)
   PUBMED   35212626
  REMARK    GeneRIF: KDM6B interacts with TFDP1 to activate P53 signaling in
            regulating mouse palatogenesis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3191)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3191)
  AUTHORS   Gong,W., Gohla,R.M., Bowlin,K.M., Koyano-Nakagawa,N., Garry,D.J.
            and Shi,X.
  TITLE     Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates
            Skeletal Muscle Myogenesis through the E2F1-DP1 Complex
  JOURNAL   J Biol Chem 290 (24), 15350-15361 (2015)
   PUBMED   25940086
  REMARK    GeneRIF: Kbtbd5 regulates skeletal muscle myogenesis through the
            regulation of E2F1-DP1 activity
REFERENCE   6  (bases 1 to 3191)
  AUTHORS   Beijersbergen,R.L., Carlee,L., Kerkhoven,R.M. and Bernards,R.
  TITLE     Regulation of the retinoblastoma protein-related p107 by G1 cyclin
            complexes
  JOURNAL   Genes Dev 9 (11), 1340-1353 (1995)
   PUBMED   7797074
REFERENCE   7  (bases 1 to 3191)
  AUTHORS   Li,Y., Slansky,J.E., Myers,D.J., Drinkwater,N.R., Kaelin,W.G. and
            Farnham,P.J.
  TITLE     Cloning, chromosomal location, and characterization of mouse E2F1
  JOURNAL   Mol Cell Biol 14 (3), 1861-1869 (1994)
   PUBMED   8114719
REFERENCE   8  (bases 1 to 3191)
  AUTHORS   Helin,K., Wu,C.L., Fattaey,A.R., Lees,J.A., Dynlacht,B.D., Ngwu,C.
            and Harlow,E.
  TITLE     Heterodimerization of the transcription factors E2F-1 and DP-1
            leads to cooperative trans-activation
  JOURNAL   Genes Dev 7 (10), 1850-1861 (1993)
   PUBMED   8405995
REFERENCE   9  (bases 1 to 3191)
  AUTHORS   Girling,R., Partridge,J.F., Bandara,L.R., Burden,N., Totty,N.F.,
            Hsuan,J.J. and La Thangue,N.B.
  TITLE     A new component of the transcription factor DRTF1/E2F
  JOURNAL   Nature 365 (6445), 468 (1993)
   PUBMED   8413592
  REMARK    Correction to:[Nature. 1993 Mar 4;362(6415):83-7. doi:
            10.1038/362083a0. PMID: 8446173]
REFERENCE   10 (bases 1 to 3191)
  AUTHORS   Girling,R., Partridge,J.F., Bandara,L.R., Burden,N., Totty,N.F.,
            Hsuan,J.J. and La Thangue,N.B.
  TITLE     A new component of the transcription factor DRTF1/E2F
  JOURNAL   Nature 362 (6415), 83-87 (1993)
   PUBMED   8446173
  REMARK    Erratum:[Nature. 1993 Sep 30;365(6445):468. doi: 10.1038/365468d0.
            PMID: 8413592]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130818.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.321299.1,
                                           SRR17253012.461903.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-739               AC130818.3         121944-122682       c
            740-814             AC130818.3         121747-121821       c
            815-881             AC130818.3         104377-104443       c
            882-988             AC130818.3         96291-96397         c
            989-1110            AC130818.3         91906-92027         c
            1111-1276           AC130818.3         90840-91005         c
            1277-1420           AC130818.3         90464-90607         c
            1421-1489           AC130818.3         90066-90134         c
            1490-1641           AC130818.3         88869-89020         c
            1642-1808           AC130818.3         88384-88550         c
            1809-1887           AC130818.3         87563-87641         c
            1888-3191           AC130818.3         83041-84344         c
FEATURES             Location/Qualifiers
     source          1..3191
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 5.78 cM"
     gene            1..3191
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /note="transcription factor Dp 1"
                     /db_xref="GeneID:21781"
                     /db_xref="MGI:MGI:101934"
     exon            1..739
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            740..814
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            815..881
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            882..988
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1110
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1276
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1420
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1489
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1641
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1808
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1887
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..3191
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3166..3171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /note="hexamer: AATAAA"
     polyA_site      3191
                     /gene="Tfdp1"
                     /gene_synonym="Dp1; Drtf1"
                     /note="major polyA site"
ORIGIN      
        1 agggtgagcc cgcgtcccgg cgccgctggc tcagggcagg gaccgccagg gccggacctc
       61 cgggccggcg cctccgcgcc cccgtcgtcc gccccgcgcg ccccgccggc cagccaggtg
      121 tggcgggggc accggccggt cgcggcggga gggcgcaggc tgggcgcgcg gccccgttcc
      181 cgccccagcc cggttcccgc gtccggtcgc atcccgcccg ccgcccagcc tcagctggag
      241 tcggcctcga cgcggcgtgg cgtgggcggc gggcaggggt cctggccacc ctccggctct
      301 gtccgcgcca gggcgcgggg ctggtggctg ggcctagtga caggtggggc gagcgggcgg
      361 gcggccggga gcccacctgt cagagtggtc ggcggcccct cggggtcttg ggcagcccgg
      421 ggtggggggt gcccgccgcg gcccgggcgg agccacgcag tgtcgtgtgc ccaagtgggg
      481 ggccttgtgc ctcggcgggg cctgtggtca ggcggggccc gcgtgcccag gtggggtgag
      541 cctgacggct gcgcgtcgct cagccaaggg tccggggtct ggccccgctg ccggtgggag
      601 ctgctggtgc ccgcagggag catttccatt tagagaggtg acttaaaatc cccgtgtggg
      661 acctgcttgg ctagctctcc tgtcgggatt gtgcaagaaa ggcccctgct gcctggaggc
      721 ctgcctctgc ctcgtgctga taagtacggt ttcttctgtg gagggtacgc agttaaagcc
      781 ttgatttcct ggatctggta acatggcaaa agatgccagt ctaattgaag ccaacggaga
      841 actaaaggtc tttatagacc agaatcttag tcctgggaaa ggtgtggtat ctcttgtagc
      901 cgtccacccg tccacagtca acacacttgg gaagcagctt ttgccaaaaa ccttcggaca
      961 gtccaatgtc aatatcacac agcaagtggt gattggcacg cctcagagac cggcagcatc
     1021 caacactatt gtggtaggaa gcccacacac tcccaacacg cattttgtgt cacagaacca
     1081 gacgtctgac tcctcacctt ggtctgctgg gaagcggaac aggaagggcg agaagaatgg
     1141 caagggcctg cggcatttct ccatgaaggt gtgtgagaag gtgcagagga aaggaaccac
     1201 ctcctacaat gaggtggctg acgagctggt ggcagagttc agcgctgccg acaaccacat
     1261 tctaccaaac gaatcagctt atgaccagaa gaacatccgg cggcgtgtct acgatgcctt
     1321 aaatgtgcta atggccatga acatcatctc caaggagaag aaggagatca aatggatcgg
     1381 cctgcccacc aactcagctc aggagtgcca gaacttagag gtagagaggc agaggaggct
     1441 ggagaggatc aaacagaagc agtcacagct ccaggagctc atcctgcagc aaattgcctt
     1501 caagaacttg gtgcagagaa atcgccaagc tgagcagcag gcccgcaggc cgcctcctcc
     1561 caactctgtc atccacttgc ccttcatcat tgtcaacacc agcaggaaga cagtcattga
     1621 ctgcagcatc tccaatgaca aatttgagta tctgtttaac tttgacaaca cgtttgagat
     1681 ccacgatgac attgaggtgc tcaagcgcat gggcatggca tgtgggctgg agtctggcaa
     1741 ctgctctgct gaagacctca aggtggccag aagtttggta ccaaaagctc tagaaccata
     1801 cgtgacagaa atggctcagg gatccattgg tggagtattc gtcacgacaa caggttctac
     1861 atccaatggc acaaggcttt ctgccagtga tttgagcaat ggtgcagatg ggatgctggc
     1921 cacgagctcc aatgggtctc agtacagcgg ctccagggtc gagacccctg tgtcctacgt
     1981 tggggaggat gatgacgacg atgatgactt taatgagaac gacgaggagg attgattact
     2041 caacccgtag acccctctcc ccttcgaatc agcttcagga aaaacacgta tagaggaaag
     2101 aaacttaaag tggggctttc tgttcttttt ggcctactcc caagaagata cccgcgagtt
     2161 ctggagttag atgtgcagct ccaagtgagg aggagtgtgc gcagtttgag cctagctgcg
     2221 gatgtgttgt gaagccagcg tgctaatgca gagcctctat ctacctttta ggattttatg
     2281 gtttctctct tttctctctt ttttttcctt ttctttcttt tttgagtttg aagcttattt
     2341 tgcccctcaa cagttgttgc tgggtttgcc gaggaaactg tactgcgccc acaccagtga
     2401 caatgacaaa gtgctgccct gcctccgatg tccagcaccc aggtggtgga cagccaggct
     2461 ttaggatgaa gttttccatt tgttaaatca tgcagtgtcc aaagaaccaa gccagtagca
     2521 cagctctact gtttaacaag cgccatatgt cttattatga ctccttcctt aaattatatt
     2581 gactgtcgta attccatcgt gtctggacac cttttctcta ttgcagcaac aaattgcgaa
     2641 gtagattttg tttgtttgtt ttctttttgt ttggaagaag tttactgcca cgctggtgca
     2701 gctatggaaa ttgtttagaa agtttgctta tggtaaattt gcctgatttc ttacaggcta
     2761 cgtttggaaa ctttttatta tatagttgtt tacatactta taagtctatc atttaaagac
     2821 gtgtactgaa acaaatgttg tatttgtttc atgagcatct tcctgtaatc tattataaag
     2881 ttgaaattaa acatagagaa tgttttaaca gttttttaac tcaaaatttg tcaatcattt
     2941 ttaatagttc tttttttata aaaagaaaaa ggaatttaag gacaggcaat agtctcttaa
     3001 aatttattca caagaaccca ttaactgcac agttgccctt agctgcctgt tctaaaatga
     3061 tggtcttttt attgaaacac aaataaactt ttctgtaata ttttatggaa tataaagaga
     3121 ctttaattgt ttgacttgtt taactaagca ctgttagttt ttattaataa aacgcgcatg
     3181 ggcattttaa a
//
