LOCUS       NM_198960               2117 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus transcription factor AP-2, epsilon (Tfap2e), mRNA.
ACCESSION   NM_198960 XM_285837
VERSION     NM_198960.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2117)
  AUTHORS   Staebler,S., Rottensteiner-Brandl,U., El Ahmad,Z.,
            Kappelmann-Fenzl,M., Arkudas,A., Kengelbach-Weigand,A.,
            Bosserhoff,A.K. and Schmidt,S.K.
  TITLE     Transcription factor activating enhancer-binding protein 2epsilon
            (AP2epsilon) modulates phenotypic plasticity and progression of
            malignant melanoma
  JOURNAL   Cell Death Dis 15 (5), 351 (2024)
   PUBMED   38773108
  REMARK    GeneRIF: Transcription factor activating enhancer-binding protein
            2epsilon (AP2epsilon) modulates phenotypic plasticity and
            progression of malignant melanoma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2117)
  AUTHORS   Amato,E. Jr., Taroc,E.Z.M. and Forni,P.E.
  TITLE     Illuminating the terminal nerve: Uncovering the link between GnRH-1
            neuron and olfactory development
  JOURNAL   J Comp Neurol 532 (3), e25599 (2024)
   PUBMED   38488687
REFERENCE   3  (bases 1 to 2117)
  AUTHORS   Lin,J.M., Mitchell,T.A., Rothstein,M., Pehl,A., Taroc,E.Z.M.,
            Katreddi,R.R., Parra,K.E., Zuloaga,D.G., Simoes-Costa,M. and
            Forni,P.E.
  TITLE     Sociosexual behavior requires both activating and repressive roles
            of Tfap2e/AP-2epsilon in vomeronasal sensory neurons
  JOURNAL   Elife 11, e77259 (2022)
   PUBMED   36111787
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2117)
  AUTHORS   Naik,A.S., Lin,J.M., Taroc,E.Z.M., Katreddi,R.R., Frias,J.A.,
            Lemus,A.A., Sammons,M.A. and Forni,P.E.
  TITLE     Smad4-dependent morphogenic signals control the maturation and
            axonal targeting of basal vomeronasal sensory neurons to the
            accessory olfactory bulb
  JOURNAL   Development 147 (8) (2020)
   PUBMED   32341026
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2117)
  AUTHORS   Taroc,E.Z.M., Naik,A.S., Lin,J.M., Peterson,N.B., Keefe,D.L. Jr.,
            Genis,E., Fuchs,G., Balasubramanian,R. and Forni,P.E.
  TITLE     Gli3 Regulates Vomeronasal Neurogenesis, Olfactory Ensheathing Cell
            Formation, and GnRH-1 Neuronal Migration
  JOURNAL   J Neurosci 40 (2), 311-326 (2020)
   PUBMED   31767679
REFERENCE   6  (bases 1 to 2117)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   7  (bases 1 to 2117)
  AUTHORS   Winger,Q., Huang,J., Auman,H.J., Lewandoski,M. and Williams,T.
  TITLE     Analysis of transcription factor AP-2 expression and function
            during mouse preimplantation development
  JOURNAL   Biol Reprod 75 (3), 324-333 (2006)
   PUBMED   16672719
REFERENCE   8  (bases 1 to 2117)
  AUTHORS   Wang,H.V., Vaupel,K., Buettner,R., Bosserhoff,A.K. and Moser,M.
  TITLE     Identification and embryonic expression of a new AP-2 transcription
            factor, AP-2 epsilon
  JOURNAL   Dev Dyn 231 (1), 128-135 (2004)
   PUBMED   15305293
  REMARK    GeneRIF: AP-2 epsilon is important for the development of the
            olfactory system.
REFERENCE   9  (bases 1 to 2117)
  AUTHORS   Tummala,R., Romano,R.A., Fuchs,E. and Sinha,S.
  TITLE     Molecular cloning and characterization of AP-2 epsilon, a fifth
            member of the AP-2 family
  JOURNAL   Gene 321, 93-102 (2003)
   PUBMED   14636996
REFERENCE   10 (bases 1 to 2117)
  AUTHORS   Feng,W. and Williams,T.
  TITLE     Cloning and characterization of the mouse AP-2 epsilon gene: a
            novel family member expressed in the developing olfactory bulb
  JOURNAL   Mol Cell Neurosci 24 (2), 460-475 (2003)
   PUBMED   14572467
  REMARK    GeneRIF: cloning and characterization; AP-2 epsilon is expressed
            most prominently in the mitral cell layer of the developing
            olfactory bulb; it is able to activate transcription in a binding
            site-dependent manner
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CO809755.1, BI134735.1, DV645135.1, DV649306.1 and BG084439.2.
            
            On Dec 30, 2006 this sequence version replaced NM_198960.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY325902.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-591               CO809755.1         38-628
            592-1074            BI134735.1         2-484
            1075-1333           DV645135.1         178-436
            1334-1827           DV649306.1         138-631
            1828-2117           BG084439.2         191-480
FEATURES             Location/Qualifiers
     source          1..2117
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 60.91 cM"
     gene            1..2117
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /note="transcription factor AP-2, epsilon"
                     /db_xref="GeneID:332937"
                     /db_xref="MGI:MGI:2679630"
     exon            1..305
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
     exon            306..788
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
     exon            789..840
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
     exon            841..1063
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1182
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1324
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..2117
                     /gene="Tfap2e"
                     /gene_synonym="AP-2e; Tcfap2e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aactagagtg catggagcag gctgagctca gagggcgggc gctgggcacc cgttgcccga
       61 cttttttcca agtgccatca gctcccgtct ggcccatttc catggacgct cccgcaggcg
      121 tcccccgctg agtaccccgt accttctgga ctcccggcag acttaccccc agcttccaga
      181 cggtgatccc cgtgggctgt aagggctccc ggctctcgcc tcgccgtcga acgagggctg
      241 tgtctccgcc acacctcacg ccccacacta cccgccccat gttggtgcac acatactccg
      301 ccatggagcg ccccgacggg ctgggcgcag cggctggcgg gacccgcctg tcgtccctgc
      361 cccaggcggc ctacgggccc gcgccgccac tgtgtcacac tcccgccgcc tctgccaccg
      421 cggactatca tcctccttac ttcccgccgc cctaccctca ggcgccgctg ccctacggcc
      481 agggtcccga cgccaccgct gcctttccgc acctcgccgc tgacccctac ggcggcctag
      541 cgcccctggc gcagccgcag cccccgcagg ccgcctgggc cgcaccccgt gcggccgccc
      601 gcgcccacga cgagccgccg ggcctgctgg cgccacccgc ccgcgctctg ggtctcgacc
      661 cgcgccgaga ctacgccgcc gcggttcccc ggctcctgca cagcctggcc gacggcgcgc
      721 acggcctggc cgatgctccc ctcggtcttc caggattggc ggagccgccc ggtctggagg
      781 aattgcaggc gatagatgac cctggaatga gcctcctgga ccaatcggtg atcaagaaag
      841 tccccattcc ctccaaagcc ggcagcctct ccaccctcgc actgtccaaa gacagcctgg
      901 ttggcggcat cagcaatccc agtgaggtct tctgctccgt gcctggccgg ctgtcgttgc
      961 tcagctcaac atccaagtac aaggtgaccg tgggggaggt gcagcggcga ctctcacctc
     1021 ctgagtgcct caacgcctcc ctcctggggg gtgtcctccg aagggccaag tccaaaaatg
     1081 gaggccggtg tctgcgggaa cggctggaga agattgggct caacttgcca gctggtcgtc
     1141 ggaaggcagc caacgtgact ctgctgacct cgctggtgga aggagaagct gtgcacctgg
     1201 ctcgggactt tggttacgtt tgtgagactg agtttccagc caaggcggct gctgagtacc
     1261 tatgccgaca gcatgccgac cctggggagc tacacagccg caagagcatg ctgctggctg
     1321 ccaagcagat ctgtaaggag tttgcagact tgatggctca ggaccgctct ccactgggca
     1381 acagccgccc ggcactcatc ctggagcctg gggtgcagag ctgtctgaca cattttagtc
     1441 tcatcactca tggctttgga gggcctgcca tctgcgctgc tctcactgcc ttccagaact
     1501 acctgctaga gtcactcaaa ggactggaaa agatgttttt aagcggcgcc ggaggtgggc
     1561 atggagaaag caaggcctcg gagaaggata ccaagcatcg gaagtaactg gctcttgttc
     1621 cctagctaaa tgactcccag agcctgagat ggggccttgg ctcctggggg taaaatgtgg
     1681 gattctattc aggccagaga gaacattttt ccagaagccc agagtgggac atagttgggt
     1741 aaaagaagaa ggcttttctg tggtttctgg taaggactcg taacgcgaac tggcatggga
     1801 aagtctggct caggggacag agcccttccc actgagatgc ctgggcagcc atgggtaccc
     1861 cgaggctgat aacacatcag aggtgctatt gaagaattag tgaccttcac ttcagtctct
     1921 tagtctcaga acccagaagg agggtccagt gggctctttg gatccttcag gctcttggag
     1981 acgagaagct ggagagaccc ctgaagaacg agatggtaca gcacaaacta ctgaacttga
     2041 acctaggctg cattaccaca gtcctgttgc tgcctgtctt atttatttat atacgatcta
     2101 attaaatttg aaaatta
//
