LOCUS       NM_019981               1054 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus testis expressed gene 101 (Tex101), mRNA.
ACCESSION   NM_019981
VERSION     NM_019981.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1054)
  AUTHORS   Qu,Y., Chen,Q., Guo,S., Ma,C., Lu,Y., Shi,J., Liu,S., Zhou,T.,
            Noda,T., Qian,J., Zhang,L., Zhu,X., Lei,X., Cao,Y., Li,W., Li,W.,
            Plachta,N., Matzuk,M.M., Ikawa,M., Duan,E., Zhang,Y. and Wang,H.
  TITLE     Cooperation-based sperm clusters mediate sperm oviduct entry and
            fertilization
  JOURNAL   Protein Cell 12 (10), 810-817 (2021)
   PUBMED   33649997
  REMARK    GeneRIF: Cooperation-based sperm clusters mediate sperm oviduct
            entry and fertilization.
REFERENCE   3  (bases 1 to 1054)
  AUTHORS   Yoshitake,H. and Araki,Y.
  TITLE     Role of the Glycosylphosphatidylinositol-Anchored Protein TEX101
            and Its Related Molecules in Spermatogenesis
  JOURNAL   Int J Mol Sci 21 (18), 6628 (2020)
   PUBMED   32927778
  REMARK    GeneRIF: Role of the Glycosylphosphatidylinositol-Anchored Protein
            TEX101 and Its Related Molecules in Spermatogenesis.
            Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1054)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1054)
  AUTHORS   Endo,S., Yoshitake,H., Tsukamoto,H., Matsuura,H., Kato,K.,
            Sakuraba,M., Takamori,K., Fujiwara,H., Takeda,S. and Araki,Y.
  TITLE     TEX101, a glycoprotein essential for sperm fertility, is required
            for stable expression of Ly6k on testicular germ cells
  JOURNAL   Sci Rep 6, 23616 (2016)
   PUBMED   27005865
  REMARK    GeneRIF: Study demonstrated that both TEX101 and Ly6k contribute
            mutually for their protein expression in the testicular germ cells,
            suggesting that the expression-balance of these two proteins is
            essential for fertile sperm formation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1054)
  AUTHORS   Tsukamoto,H., Yoshitake,H., Mori,M., Yanagida,M., Takamori,K.,
            Ogawa,H., Takizawa,T. and Araki,Y.
  TITLE     Testicular proteins associated with the germ cell-marker, TEX101:
            involvement of cellubrevin in TEX101-trafficking to the cell
            surface during spermatogenesis
  JOURNAL   Biochem Biophys Res Commun 345 (1), 229-238 (2006)
   PUBMED   16678124
  REMARK    GeneRIF: From these results we concluded that cellubrevin-dependent
            membrane trafficking is involved in TEX101-transport to the surface
            of male germ cells.
REFERENCE   7  (bases 1 to 1054)
  AUTHORS   Takayama,T., Mishima,T., Mori,M., Ishikawa,T., Takizawa,T.,
            Goto,T., Suzuki,M., Araki,Y., Matsubara,S. and Takizawa,T.
  TITLE     TEX101 is shed from the surface of sperm located in the caput
            epididymidis of the mouse
  JOURNAL   Zygote 13 (4), 325-333 (2005)
   PUBMED   16388701
REFERENCE   8  (bases 1 to 1054)
  AUTHORS   Sleight,S.B., Miranda,P.V., Plaskett,N.W., Maier,B., Lysiak,J.,
            Scrable,H., Herr,J.C. and Visconti,P.E.
  TITLE     Isolation and proteomic analysis of mouse sperm detergent-resistant
            membrane fractions: evidence for dissociation of lipid rafts during
            capacitation
  JOURNAL   Biol Reprod 73 (4), 721-729 (2005)
   PUBMED   15917346
REFERENCE   9  (bases 1 to 1054)
  AUTHORS   Takayama,T., Mishima,T., Mori,M., Jin,H., Tsukamoto,H.,
            Takahashi,K., Takizawa,T., Kinoshita,K., Suzuki,M., Sato,I.,
            Matsubara,S., Araki,Y. and Takizawa,T.
  TITLE     Sexually dimorphic expression of the novel germ cell antigen TEX101
            during mouse gonad development
  JOURNAL   Biol Reprod 72 (6), 1315-1323 (2005)
   PUBMED   15689535
  REMARK    GeneRIF: may play an important physiological role in germ cell
            development
REFERENCE   10 (bases 1 to 1054)
  AUTHORS   Kurita,A., Takizawa,T., Takayama,T., Totsukawa,K., Matsubara,S.,
            Shibahara,H., Orgebin-Crist,M.C., Sendo,F., Shinkai,Y. and Araki,Y.
  TITLE     Identification, cloning, and initial characterization of a novel
            mouse testicular germ cell-specific antigen
  JOURNAL   Biol Reprod 64 (3), 935-945 (2001)
   PUBMED   11207211
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC161488.7 and
            AC161166.7.
            
            On Nov 17, 2006 this sequence version replaced NM_019981.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048475.1, AB022914.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                AC161488.7         152827-152925
            100-204             AC161166.7         875-979
            205-345             AC161166.7         1085-1225
            346-531             AC161166.7         1659-1844
            532-663             AC161166.7         2918-3049
            664-1054            AC161166.7         3156-3546
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 12.13 cM"
     gene            1..1054
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /note="testis expressed gene 101"
                     /db_xref="GeneID:56746"
                     /db_xref="MGI:MGI:1930791"
     exon            1..99
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /inference="alignment:Splign:2.1.0"
     exon            100..204
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..893
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /note="testis-expressed protein 101; TES101-reactive
                     protein; testis-expressed sequence 101 protein"
                     /codon_start=1
                     /product="testis-expressed protein 101 precursor"
                     /protein_id="NP_064365.1"
                     /db_xref="CCDS:CCDS20959.1"
                     /db_xref="GeneID:56746"
                     /db_xref="MGI:MGI:1930791"
                     /translation="MGACRIQYVLLIFLLIASRWTLVQNTYCQVSQTLSLEDDPGRTF
                     NWTSKAEQCNPGELCQETVLLIKADGTRTVVLASKSCVSQGGEAVTFIQYTAPPGLVA
                     ISYSNYCNDSLCNNKDSLASVWRVPETTATSNMSGTRHCPTCVALGSCSSAPSMPCAN
                     GTTQCYQGRLEFSGGGMDATVQVKGCTTTIGCRLMAMIDSVGPMTVKETCSYQSFLQP
                     RKAEIGASQMPTSLWVLELLFPLLLLPLTHFP"
     exon            205..345
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /inference="alignment:Splign:2.1.0"
     exon            346..531
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /inference="alignment:Splign:2.1.0"
     exon            532..663
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /inference="alignment:Splign:2.1.0"
     exon            664..1054
                     /gene="Tex101"
                     /gene_synonym="1700008H15Rik; TES101RP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaacactgc acacggtacc ggtcgccatc gaagctgggt gcacggagga cacactgtgg
       61 cctgaaaaaa attttcctgg tttaaaaaga aatagaccgt tcccaggtct tgatcggctc
      121 ttcccaacct tagagaagcc atgggagcct gccgcatcca gtatgtcctg ctcatctttc
      181 ttctaatcgc ctcacgttgg actctggtcc aaaataccta ctgccaggtg agtcaaaccc
      241 tgagtctgga agacgatcca ggccgtacct ttaactggac ttcaaaggct gagcagtgca
      301 atccaggaga actttgccaa gaaacggtcc tgttgattaa agcagatgga accaggaccg
      361 tcgttttggc cagtaagagc tgtgtttctc aaggaggaga ggcggtgact ttcatccagt
      421 atactgcacc tcctggcctg gttgccatct cttacagtaa ctactgcaat gactccctct
      481 gcaacaacaa agacagccta gcgtcagtct ggcgagtgcc agagaccaca gcaacctcca
      541 acatgtcagg aacccgccac tgcccgacat gtgtggccct gggctcctgt tccagtgccc
      601 cctctatgcc ctgtgccaat ggcacaactc agtgctatca aggaagactt gaattctctg
      661 gaggaggcat ggacgccacc gtgcaagtta aaggctgcac cactacgatc ggctgcagac
      721 tgatggccat gatagactca gtgggaccca tgacagtgaa ggagacctgt agttaccagt
      781 cattccttca gccccggaag gcagaaatcg gggcctctca gatgcccact tcactgtggg
      841 tgctggagct actgtttccg ttactgctgc tccccctcac ccacttccct tgaagaggac
      901 actgggggtc aggggaggcc ttggtcctag acactggact ttgcctagga gggagccttc
      961 tgcctgctga tactggaaga agtgggggtg gggtgtgaag agcagagaaa gaggatgcat
     1021 gtgtatttga cacaataaaa ttagtgattt gcta
//
