LOCUS       NM_175307               2288 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus terminal nucleotidyltransferase 5B (Tent5b), mRNA.
ACCESSION   NM_175307
VERSION     NM_175307.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2288)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2288)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627228.31.
            
            On Oct 19, 2007 this sequence version replaced NM_175307.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK137659.1, AK028944.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-431               AL627228.31        56048-56478
            432-2288            AL627228.31        61999-63855
FEATURES             Location/Qualifiers
     source          1..2288
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 66.25 cM"
     gene            1..2288
                     /gene="Tent5b"
                     /gene_synonym="4732473B16Rik; Fam46b"
                     /note="terminal nucleotidyltransferase 5B"
                     /db_xref="GeneID:100342"
                     /db_xref="MGI:MGI:2140500"
     exon            1..431
                     /gene="Tent5b"
                     /gene_synonym="4732473B16Rik; Fam46b"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..1451
                     /gene="Tent5b"
                     /gene_synonym="4732473B16Rik; Fam46b"
                     /EC_number="2.7.7.19"
                     /note="protein FAM46B; putative nucleotidyltransferase
                     FAM46B; family with sequence similarity 46, member B;
                     non-canonical poly(A) polymerase FAM46B"
                     /codon_start=1
                     /product="terminal nucleotidyltransferase 5B"
                     /protein_id="NP_780516.1"
                     /db_xref="CCDS:CCDS18748.1"
                     /db_xref="GeneID:100342"
                     /db_xref="MGI:MGI:2140500"
                     /translation="MMPSESGAESLEQPAAQVGTGAASAVATAGAAGGGPDPEASSAS
                     LGRHQSRLSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEHGLRVH
                     SVRLHGSAASHVLHPESGLGYKDLDLVFQMDLRSEVSFQLTKAVVLACLLDFLPAGVS
                     RAKITPLTLKEAYVQKLVKVCTDLDRWSLISLSNKSGKNVELKFVDSVRRQFEFSIDS
                     FQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRG
                     GGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRILERYLEAHFGGA
                     EAARRYACLVTLHQVVNESTVCLMSHERRQTLDLIAMLALQALAEQGPAAMAALAWRR
                     PGSDGVVPATVNYYVTPMQPLLPRAHSYPTWLPCN"
     exon            432..2288
                     /gene="Tent5b"
                     /gene_synonym="4732473B16Rik; Fam46b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2265..2270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tent5b"
                     /gene_synonym="4732473B16Rik; Fam46b"
                     /note="hexamer: AATAAA"
     polyA_site      2286
                     /gene="Tent5b"
                     /gene_synonym="4732473B16Rik; Fam46b"
                     /note="major polyA site"
ORIGIN      
        1 ggctctaaga tctgttagtc ctccctgccg tcgggggtgt tccctgggtt tgcctcgccg
       61 ccgccgggtc cccgcacccc gccttggccc gtgcacagcc actctccctg ccctcctcgc
      121 cttcaccatt cccgggtttc tgccgtccag gcaccggggc cgggtgaatg atgccgtcgg
      181 agagtggagc tgagagcctg gagcagccag ctgcgcaggt ggggaccggt gcagcctcgg
      241 cagtggccac ggctggggcg gccggcggcg gcccggaccc ggaggcctcc tcggcctccc
      301 tgggacggca ccagagtcgg ctgagctggc cacaggtgaa gcggctggac gcgctgctga
      361 aagagccgat ccccattcac ggacgaggca acttccccac gctgagcgtg cagccccagc
      421 agatcgtgca ggtggtccgc agcagcttgg aagaacacgg actgcgtgta cacagcgtgc
      481 gcctgcatgg ctcagccgcc agccacgtgc tgcaccccga gagcggccta ggctacaagg
      541 acctggactt ggtgttccag atggacctgc ggagtgaggt gtccttccag ctcaccaagg
      601 cagtggtcct ggcttgcctg ctggacttcc tgccagcggg agtgagccgg gccaagataa
      661 cgccgctgac actcaaggaa gcctacgtgc agaagctggt caaagtgtgc accgacctgg
      721 accgctggag cctcatctct ctgtccaaca agagcggtaa gaacgtggaa ctcaagttcg
      781 tggactctgt gagacgccag ttcgaattca gcatcgactc cttccaaatc atcttggact
      841 cgctgctcct ctttggccag tgctcatcca cacctatgtc ggaggccttc caccctacgg
      901 tgaccgggga gagcctctat ggggacttcg ctgaggcctt ggagcacctg cagcaccgtg
      961 tcatcgccac acgcagcccc gaggagatcc gaggtggtgg cctcctcaag tactgccacc
     1021 tcctggtacg gggcttccgg ccaaggccca gcactgacgt tcgcgccctc cagcgataca
     1081 tgtgttcccg tttcttcatc gactttccgg acctggtgga acagaggcgc attctggagc
     1141 gctacctgga ggcccacttt ggcggagcgg aagcagcccg ccggtatgct tgccttgtga
     1201 cactgcacca ggtggtcaac gagagcacag tgtgtctcat gagccacgag cgccgccaga
     1261 ccctggacct tattgccatg ctcgccctcc aggcactggc tgaacagggc cctgctgcca
     1321 tggctgccct ggcctggcga cgtcctggtt cagatggggt ggtcccagcc actgttaatt
     1381 actatgtgac ccccatgcag ccactgctgc cccgagctca ctcctatcct acctggctgc
     1441 cttgcaactg actctgatcc tggccagaag ggaatgagcg ccatggggtg gggtggggtc
     1501 atcaggtatg tgtggaggat gtaagcagac acaggccacc tgtgccagct ggcccggcac
     1561 tatagggttg ggcctttgaa cagaccagac tttcctgcac aaggctccta tgggcttaaa
     1621 gccaagtcag ggttcttgac agaaggaccc attggtcatc atactgtact cttggacctg
     1681 cgtgactgtg ggacacagag gctgcctgtc tggaaatgac aaagtcagct tgtgtggtag
     1741 cctcagtagc aacaccttgg gttgatttca atggcttaga aagggtcagc ccacagggac
     1801 ccagatgctc ctatagtggc cacaatgtga tatcatgtga cagggctatt cagttggggt
     1861 acggttgggc cattcacaga gcctggggat ccaacctcgc tgatcactag gaagagataa
     1921 actaaggcat aaagcaactc cttggggttt gggtgggatg ggagttcagt ctcctgaaac
     1981 ctccttgccc taaaccgtga ggatttcctg agggccgagg tatacagtgg tgcgacccat
     2041 acacatccca gtgcctcacc catctccttt ccctgtgcct tccaggagcc ctgctgtctg
     2101 ggcactattg ttggaggctg ctgggttcca aagctgccac agtcgagttg accactccct
     2161 ccccccactt gcttggtaat aggactctca cttatcggga aggcggcaga tcccatcccc
     2221 ttgccacacc tctggatttg ttgctatttt gcactcttcc caccaataaa aaatgtctgc
     2281 actgacca
//
