LOCUS       NM_001372333            4937 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus terminal nucleotidyltransferase 4B (Tent4b),
            transcript variant 4, mRNA.
ACCESSION   NM_001372333 XM_017312651
VERSION     NM_001372333.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4937)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126034.4 and AC155170.3.
            
            On Dec 20, 2022 this sequence version replaced NM_001372333.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC080314.1, SRR17253012.3015715.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-981               AC126034.4         14544-15524         c
            982-1105            AC155170.3         91712-91835
            1106-1152           AC155170.3         94069-94115
            1153-1273           AC155170.3         94836-94956
            1274-1381           AC155170.3         95980-96087
            1382-1510           AC155170.3         97576-97704
            1511-1724           AC155170.3         99111-99324
            1725-1851           AC155170.3         100426-100552
            1852-1955           AC155170.3         100653-100756
            1956-2143           AC155170.3         100857-101044
            2144-2308           AC155170.3         103580-103744
            2309-4937           AC155170.3         105570-108198
FEATURES             Location/Qualifiers
     source          1..4937
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 43.06 cM"
     gene            1..4937
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /note="terminal nucleotidyltransferase 4B"
                     /db_xref="GeneID:214627"
                     /db_xref="MGI:MGI:1917820"
     exon            1..981
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     CDS             383..2485
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /EC_number="2.7.7.19"
                     /note="isoform c is encoded by transcript variant 4;
                     PAP-associated domain-containing protein 5; TRF4-2;
                     topoisomerase-related function protein 4-2; TUTase 3; PAP
                     associated domain containing 5; terminal
                     uridylyltransferase 3; non-canonical poly(A) RNA
                     polymerase PAPD5; terminal guanylyltransferase; terminal
                     nucleotidyltransferase 4A"
                     /codon_start=1
                     /product="terminal nucleotidyltransferase 4B isoform c"
                     /protein_id="NP_001359262.1"
                     /db_xref="GeneID:214627"
                     /db_xref="MGI:MGI:1917820"
                     /translation="MDPRIAWFQPEQLGPSNSLWMQIWETTQGLRNLYFNHHCHSSGA
                     SSASGGSGSGPGSPGGTAPAPAGMFRSGERPLGGLAVPAEQRDFLPLETTNNNNNHHQ
                     PAAWARRASAGPSASPVPSAPSSPRPAAALPASESTDPASGSSNKRKRDNKASTYGLN
                     YSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEE
                     EKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLE
                     EALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKK
                     YPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGV
                     LLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGND
                     VGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTDEVATYRDW
                     ISKQWGLQNRPEPSCNGNGVTLIVDTQQLDKCNNNLSEEKEALGKCRSNASEPLSKHS
                     SNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQLLCRPPTVTRVGSQDVSLEVSQAVG
                     KMQSTQTTNTPNNANKSQHGSARLFRSSSKGFQGTAQTSHGALMTSKQHQGKSNTQYY
                     HGKKRRHKRDAPLSELCR"
     exon            982..1105
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1152
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1273
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1381
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1510
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1724
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1851
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1852..1955
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2143
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            2144..2308
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..4937
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4913..4918
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /note="hexamer: AGTAAA"
     polyA_site      4928
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
     polyA_site      4937
                     /gene="Tent4b"
                     /gene_synonym="5730445M16Rik; 5830428A09; Papd5"
                     /note="major polyA site"
ORIGIN      
        1 gccgagcagc acggacgcta cggagcaggc gcgtcccgct gccgccgccg ctgccgccgc
       61 cgccgccgct gctgctgccg ccgccgccac caccgccgcc gccgctcgcc cttctcggga
      121 tccgccgccg ccatttgcac gggaaccccg gtgacagggg ctcggcggag gggcggaggg
      181 aggggggagg gcctgcgagc cccgagggcg ggagcgacgc cgccggcgcc ggccaggctc
      241 cctgcgctac cgcgccgccc gtggcggaac ccgggtggca gcggcggcgg cggccgaggg
      301 cgggcgtgcg cctgaggcag cggcggcggc ggcggccctg cgggcggccg ggaggggcgg
      361 gggcagcggc cgccgccgtt tgatggatcc gaggatcgcc tggttccagc cagagcagct
      421 cggaccgtcc aatagtctgt ggatgcagat ctgggagacg acccaggggc tgaggaacct
      481 ctacttcaac caccactgtc acagcagcgg cgcgagcagc gcgagcggcg ggagcggcag
      541 cggccccggc agccccggcg gcacggcccc ggccccggcc ggcatgttcc gctcggggga
      601 gcgcccactg ggcggcctcg ccgtgcccgc ggagcagcgg gacttcctgc ccctggagac
      661 gaccaacaac aacaacaatc accaccagcc ggcggcctgg gcacggcggg catcggcggg
      721 cccctcggcg tcgccggtcc catcggctcc ctcgtccccg cgaccggcgg ccgcactccc
      781 cgcctccgag tctaccgacc cggcctcggg cagcagcaac aagaggaaac gtgacaacaa
      841 ggccagcacc tacggactca actacagcct gctgcagccc agcggagggc gcgcggccgg
      901 aggcggacgg gcggacggcg gcgggggcgt gtacagcggg accccgtgga agcgacggaa
      961 ctacaaccag ggagtcgtgg gtctgcatga agaaatcagt gatttttatg agtacatgtc
     1021 tcccagaccc gaggaagaga agatgcggat ggaggtagtg agcaggatcg agagtgtgat
     1081 taaagagctc tggcccagtg ctgatgtcca gatatttgga agttttaaaa ctggcctgta
     1141 tttacctacc agtgacatcg atcttgtggt gtttgggaag tgggagaacc tgcctctctg
     1201 gaccctggaa gaagcccttc ggaaacacaa agtcgctgac gaggattccg tgaaagttct
     1261 agacaaagca acggttccta ttattaaatt aacagattct tttactgaag tgaaagttga
     1321 tatcagcttt aatgtccaga atggcgtgag agcagcagac ctcattaaag attttactaa
     1381 gaaatatcct gtattgccat acttggtttt agtattgaaa cagttcttat tacagaggga
     1441 ccttaatgaa gtatttacag gtggaattgg ttcttatagt ctctttttaa tggcagtcag
     1501 tttccttcag ttacatccca gggaagatgc ttgcatcccc aatacaaact atggtgttct
     1561 cttaatagag ttttttgaat tatatggacg gcacttcaat tacttaaaga ctggcatccg
     1621 gataaaggat ggtggttcct atgtggccaa agatgaagta cagaaaaata tgcttgatgg
     1681 ctaccggccg tcaatgcttt atatcgaaga tcctttacaa ccaggtaatg atgttggaag
     1741 gagttcctat ggggccatgc aggtgaaaca ggcctttgat tatgcctatg tggtattgag
     1801 tcatgcagtg tcaccgattg caaagtacta tcccaacaat gaaacagaga gcatattagg
     1861 tagaataatt agagtgacgg atgaagttgc cacgtataga gattggatat caaaacagtg
     1921 gggcttgcag aataggcccg agccatcatg caacggaaat ggtgttacct tgatagtaga
     1981 tactcagcag ttagataagt gtaataataa tctgtctgaa gaaaaggaag cccttggaaa
     2041 atgtagaagt aacgcctcgg aacctcttag taaacactct tcaaactctt catcaggtcc
     2101 agtgtcctcc tcctctgcca cgcagtccag ctctagtgac gtcgattctg atgcaacgcc
     2161 atgcaaaacc cccaaacagc tgctctgccg tccacccact gtcacccggg taggctcaca
     2221 ggatgtctcc ttggaggtct ctcaggcagt tgggaaaatg cagagcactc aaaccactaa
     2281 cacacccaac aacgccaaca aatcacagca tggatcagca aggctcttcc gttcttccag
     2341 caaaggcttc caaggtacag ctcaaaccag ccatggggcc ttgatgacaa gcaaacagca
     2401 tcaaggcaaa tccaatactc agtattacca tggcaaaaag aggagacaca agagggacgc
     2461 gcccctctca gagctttgta gatagtcggc gctctgcgac agactgtctt ctgtgtgcaa
     2521 tgatctcgtg ctcaggacag ttgcacaggg actcctggga cggcaggagc ctcacactgt
     2581 tcagacgttg atttagcaac tgcgtttttt cccagctcgc cacggaatgg atcatgaaga
     2641 ctgacaactg caaaaacaaa aagcaagcaa aaaaaagggg gaaaggctgc ttatgtgata
     2701 agtcatgtgc tacaacaggg tcattttaag atttaaagct tgaatgtaaa ataaatatat
     2761 ttctcattgg ctttatgcag agttataggg gctagtgctc agtgtgggta gctgacagga
     2821 agagagcagt gtcaaggaga tgggtgggca ggtcagcagg agcatctcat gggaagtcag
     2881 actccgaggg aaaggagttt gtgcatggtt ttttttaaaa aataattttg catatatttg
     2941 ccattttatt gtgtgtatat atagaagacc atataggaaa ttgatatttg taatagtgga
     3001 tttgttaata ctttttacat aacattacta tttgaattgt aaacagattt ttttctcagg
     3061 attagtttga agaataattg agttgtcact cttaacacat gcagggaagt gattagctct
     3121 ggtcctgtct gttttcttca gcattgaaat gacttcatag aacccttgtg acctgcttca
     3181 aaattctttc ctctctaagc aaaaggttta tggtggcaaa tgatgtttat tttattttgt
     3241 aaaaaagaga aaaatgtact gtgtacttgt gtatacactg aacaacctct agctgtctct
     3301 ccgaatgaac acacctgctc tggatccagt gctgttgtct tcctgggcac tgggccgtag
     3361 caggccttgt gtgtgtttcc tagcagtctt ttcttcccct ccctcctctt cttcctcaaa
     3421 ggaaacgaaa ggcctccctg ggcctgggct gttcctgtca cagtgtggct gacctctagc
     3481 tccacagccc ttgttagctc gcatgctggt tcctctgacc ctgcgttcca tgtgcttgtg
     3541 gcgtcctctc attctttcta ggttcctgct tactgctgtg ggagagagta actgtaaaca
     3601 gctttaatga aatcatactt ataaaaacta ttttcttata ctccacttta tgcttttggt
     3661 attgtcgatc tttaaaaatt aaatggtctt tgataatgga tcgatttttg tattgcctta
     3721 ttaagaccaa atacttcttg tcatcccatt ctttatcctc tcctttaatg gaattgctgt
     3781 ctttaattaa aactttgtaa acactggctt gttttaatca tcctgtaact taggctgtgg
     3841 tcagctacaa gcgcagatgt gtaatcctgt tactcattgc cagctgagtc ttgagactcg
     3901 ggtggggtac ttaacacaat gcatcgtaca cgctctgctc gctcgctcgt cagcagagtg
     3961 gtcttggagg tgaaagccct cgtgtctagc atcagtgtgt gtgtgtgact ctgttcagta
     4021 cggccgtttc cgagatggga ttcttttata tgtgtatgtg tgaagtactg ttggcattta
     4081 ggcatttctt ttctatacac ttaggaaata ctgaagacca atcagaccat taatggacac
     4141 ttagtgcaac tttttataat gagaataatg ctataaagta agaccaaaac cggtgtcatc
     4201 actgaaatta acaattttca atatgttcat attttaattt acaatgggaa aaaatgtgtt
     4261 ccacaactgg aaactcacag tactgtgtaa actgtgtaag attttaaatg tgatgttatt
     4321 ttgactgttc tcaattttag agtcacattt tattctgatc agaattttta tcaagatgtt
     4381 gaagttttgt tgttttgaaa ctagtttgtc ataacatatt gtgcataatc acagtattta
     4441 ttttgtaggg cttgtggatg tgtagactta tgtttactgc taagggaaca attatttata
     4501 aaaaaaatat taaatccagt attagctgcc tatttcagac acttaacacc tgcagagatc
     4561 tgtgttacat ttaccacact gaagtttttt taaagaatca ccctcattgt tgaaagtaaa
     4621 tgtactctta ggtgggttat tagtgtccaa taagcatgtg attatattaa ggtggtggta
     4681 gcgggaagat aatcttgatt ccattgggaa tcttaggttt tcgtaaattt attgggaaaa
     4741 tagtttttcc tgtactgctg atgtttcttt ttggtaaaca gtatctttct aaaagaaaaa
     4801 gcatgaagga gaattgaggt gtgtatacat ttccccagat gaccagcatt gtattcgtga
     4861 atactgtgta tctggaatga gcagtgtgca agctgttcat ttttcaatct gaagtaaaat
     4921 actttcaaga actttta
//
