LOCUS       NM_011857              10978 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus teneurin transmembrane protein 3 (Tenm3), transcript
            variant 1, mRNA.
ACCESSION   NM_011857
VERSION     NM_011857.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10978)
  AUTHORS   Lo Giudice,Q., Wagener,R.J., Abe,P., Frangeul,L. and Jabaudon,D.
  TITLE     Developmental emergence of first- and higher-order thalamic neuron
            molecular identities
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39348458
REFERENCE   2  (bases 1 to 10978)
  AUTHORS   Liakath-Ali,K., Refaee,R. and Sudhof,T.C.
  TITLE     Cartography of teneurin and latrophilin expression reveals
            spatiotemporal axis heterogeneity in the mouse hippocampus during
            development
  JOURNAL   PLoS Biol 22 (5), e3002599 (2024)
   PUBMED   38713721
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10978)
  AUTHORS   Hunyara,J.L., Daly,K.M., Torres,K., Yurgel,M.E., Komal,R.,
            Hattar,S. and Kolodkin,A.L.
  TITLE     Teneurin-3 regulates the generation of non-image-forming visual
            circuitry and responsiveness to light in the suprachiasmatic
            nucleus
  JOURNAL   PLoS Biol 21 (12), e3002412 (2023)
   PUBMED   38048352
  REMARK    GeneRIF: Teneurin-3 regulates the generation of non-image-forming
            visual circuitry and responsiveness to light in the suprachiasmatic
            nucleus.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10978)
  AUTHORS   Tran,H., Sawatari,A. and Leamey,C.A.
  TITLE     Ten-m3 plays a role in the formation of thalamostriatal projections
  JOURNAL   Dev Neurobiol 83 (7-8), 255-267 (2023)
   PUBMED   37700636
  REMARK    GeneRIF: Ten-m3 plays a role in the formation of thalamostriatal
            projections.
REFERENCE   5  (bases 1 to 10978)
  AUTHORS   Rogerson-Wood,L., Petersen,J., Kairouz,A., Goldsbury,C.S.,
            Sawatari,A. and Leamey,C.A.
  TITLE     An Early Enriched Experience Drives an Activated Microglial Profile
            at Site of Corrective Neuroplasticity in Ten-m3 Knock-Out Mice
  JOURNAL   eNeuro 10 (1) (2023)
   PUBMED   36635245
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 10978)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
REFERENCE   7  (bases 1 to 10978)
  AUTHORS   Ben-Zur,T., Feige,E., Motro,B. and Wides,R.
  TITLE     The mammalian Odz gene family: homologs of a Drosophila pair-rule
            gene with expression implying distinct yet overlapping
            developmental roles
  JOURNAL   Dev Biol 217 (1), 107-120 (2000)
   PUBMED   10625539
REFERENCE   8  (bases 1 to 10978)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   9  (bases 1 to 10978)
  AUTHORS   Oohashi,T., Zhou,X.H., Feng,K., Richter,B., Morgelin,M.,
            Perez,M.T., Su,W.D., Chiquet-Ehrismann,R., Rauch,U. and Fassler,R.
  TITLE     Mouse ten-m/Odz is a new family of dimeric type II transmembrane
            proteins expressed in many tissues
  JOURNAL   J Cell Biol 145 (3), 563-577 (1999)
   PUBMED   10225957
REFERENCE   10 (bases 1 to 10978)
  AUTHORS   Neophytou,P.I., Muir,E.M. and Hutton,J.C.
  TITLE     A subtractive cloning approach to the identification of mRNAs
            specifically expressed in pancreatic beta-cells
  JOURNAL   Diabetes 45 (2), 127-133 (1996)
   PUBMED   8549854
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125536.3, AC126689.4, AC132120.3, AC140446.5 and AC164420.4.
            
            On Mar 21, 2009 this sequence version replaced NM_011857.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB025412.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-281               AC125536.3         137047-137327
            282-560             AC126689.4         196425-196703       c
            561-798             AC132120.3         116921-117158       c
            799-1037            AC132120.3         95349-95587         c
            1038-1160           AC132120.3         67224-67346         c
            1161-1375           AC132120.3         49112-49326         c
            1376-1586           AC132120.3         43145-43355         c
            1587-1688           AC132120.3         42528-42629         c
            1689-1883           AC132120.3         42170-42364         c
            1884-2084           AC132120.3         40867-41067         c
            2085-2270           AC132120.3         35502-35687         c
            2271-2297           AC140446.5         1877-1903
            2298-2444           AC140446.5         4372-4518
            2445-2661           AC140446.5         14170-14386
            2662-2781           AC140446.5         15428-15547
            2782-3043           AC140446.5         16094-16355
            3044-3311           AC140446.5         21367-21634
            3312-3455           AC140446.5         22879-23022
            3456-3705           AC140446.5         27101-27350
            3706-3726           AC140446.5         27988-28008
            3727-3959           AC140446.5         35951-36183
            3960-4114           AC140446.5         37320-37474
            4115-4989           AC140446.5         38237-39111
            4990-5165           AC140446.5         58134-58309
            5166-5401           AC140446.5         60496-60731
            5402-5698           AC164420.4         6318-6614
            5699-7310           AC164420.4         9958-11569
            7311-7441           AC164420.4         14721-14851
            7442-10978          AC164420.4         17658-21194
FEATURES             Location/Qualifiers
     source          1..10978
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 27.02 cM"
     gene            1..10978
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /note="teneurin transmembrane protein 3"
                     /db_xref="GeneID:23965"
                     /db_xref="MGI:MGI:1345183"
     exon            1..281
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..8197
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     teneurin-3; ten-3; tenascin-M3; protein Odd Oz/ten-m
                     homolog 3; odd Oz/ten-m homolog 3"
                     /codon_start=1
                     /product="teneurin-3 isoform 1"
                     /protein_id="NP_035987.3"
                     /db_xref="CCDS:CCDS22303.1"
                     /db_xref="GeneID:23965"
                     /db_xref="MGI:MGI:1345183"
                     /translation="MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSS
                     ETLKAFDHDSSRLLYGNRVKDLVHREADEYTRQGQNFTLRQLGVCESATRRGVAFCAE
                     MGLPHRGYSISAGSDADTENEAVMSPEHAMRLWGRGVKSGRSSCLSSRSNSALTLTDT
                     EHENRSDSESEQPSNNPGQPTLQPLPPSHKQHPAQHHPSITSLNRNSLTNRRNQSPAP
                     PAALPAELQTTPESVQLQDSWVLGSNVPLESRHFLFKTGTGTTPLFSTATPGYTMASG
                     SVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWRCTALCAVGVSVLLAILLSYFIAMHLF
                     GLNWHLQQTENDTFENGKVNSDTVPTNTVSLPSGDNGKLGGFTHENNTIDSGELDIGR
                     RAIQEVPPGIFWRSQLFIDQPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFVELLD
                     GSRLIAREQRNLVESERAGRQARSVSLHEAGFIQYLDSGIWHLAFYNDGKNPEQVSFN
                     TIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLC
                     FSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGENCEEADCLDPGCSNHGV
                     CIHGECHCNPGWGGSNCEILKTMCADQCSGHGTYLQESGSCTCDPNWTGPDCSNEICS
                     VDCGSHGVCMGGSCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTI
                     AHYLDKIVKEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEG
                     DGLIDCMDPDCCLQSSCQNQPYCRGLPDPQDIISQSLQTPSQQAAKSFYDRISFLIGS
                     DSTHVLPGESPFNKSLASVIRGQVLTADGTPLIGVNVSFLHYSEYGYTITRQDGMFDL
                     VANGGASLTLVFERSPFLTQYHTVWIPWNVFYVMDTLVMKKEENDIPSCDLSGFVRPS
                     PIIVSSPLSTFFRSSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKSVLKIT
                     MTQAVIPFNLMKVHLMVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSEAVV
                     SVGYEYESCLDLTLWEKRTAVLQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENQ
                     FISQQPPVVSSIMGNGRRRSISCPSCNGQADGNKLLAPVALACGIDGSLYVGDFNYVR
                     RIFPSGNVTSVLELRNKDFRHSSNPAHRYYLATDPVTGDLYVSDTNTRRIYRPKSLTG
                     AKDLTKNAEVVAGTGEQCLPFDEARCGDGGKAVEATLMSPKGMAIDKNGLIYFVDGTM
                     IRKVDQNGIISTLLGSNDLTSARPLTCDTSMHISQVRLEWPTDLAINPMDNSIYVLDN
                     NVVLQITENRQVRIAAGRPMHCQVPGVEYPVGKHAVQTTLESATAIAVSYSGVLYITE
                     TDEKKINRIRQVTTDGEISLVAGIPSECDCKNDANCDCYQSGDGYAKDAKLNAPSSLA
                     ASPDGTLYIADLGNIRIRAVSKNKPLLNSMNFYEVASPTDQELYIFDINGTHQYTVSL
                     VTGDYLYNFSYSNDNDVTAVTDSNGNTLRIRRDPNRMPVRVVSPDNQVIWLTIGTNGC
                     LKSMTAQGLELVLFTYHGNSGLLATKSDETGWTTFFDYDSEGRLTNVTFPTGVVTNLH
                     GDMDKAITVDIESSSREEDVSITSNLSSIDSFYTMVQDQLRNSYQIGYDGSLRIFYAS
                     GLDSHYQTEPHVLAGTANPTVAKRNMTLPGENGQNLVEWRFRKEQAQGKVNVFGRKLR
                     VNGRNLLSVDFDRTTKTEKIYDDHRKFLLRIAYDTSGHPTLWLPSSKLMAVNVTYSST
                     GQIASIQRGTTSEKVDYDSQGRIVSRVFADGKTWSYTYLEKSMVLLLHSQRQYIFEYD
                     MWDRLSAITMPSVARHTMQTIRSIGYYRNIYNPPESNASIITDYNEEGLLLQTAFLGT
                     SRRVLFKYRRQTRLSEILYDSTRVSFTYDETAGVLKTVNLQSDGFICTIRYRQIGPLI
                     DRQIFRFSEDGMVNARFDYSYDNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGK
                     FGVIYYDINQIISTAVMTYTKHFDAHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKRE
                     IKIGPFANTTKYAYEYDVDGQLQTVYLNEKIMWRYNYDLNGNLHLLNPSSSARLTPLR
                     YDLRDRITRLGDVQYRLDEDGFLRQRGTEIFEYSSKGLLTRVYSKGSGWTVIYRYDGL
                     GRRVSSKTSLGQHLQFFYADLTYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGD
                     EFYIASDNTGTPLAVFSSNGLMLKQIQYTAYGEIYFDSNVDFQLVIGFHGGLYDPLTK
                     LIHFGERDYDILAGRWTTPDIEIWKRIGKDPAPFNLYMFRNNNPASKIHDVKDYITDV
                     NSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELVKSQQWEDVPPIFGVQQQVARQAKAF
                     LSLGKMAEVQVSRRKAGAEQSWLWFATVKSLIGKGVMLAVSQGRVQTNVLNIANEDCI
                     KVAAVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLGTLRLTSGRKALENGINVTVS
                     QSTTVVNGRTRRFADVEMQFGALALHVRYGMTLDEEKARILEQARQRALARAWAREQQ
                     RVRDGEEGARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQYPELADSANNIQFLRQSEI
                     GKR"
     exon            282..560
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            561..798
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            799..1037
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1160
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1375
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1586
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1688
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1883
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            1884..2084
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2270
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2297
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2444
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            2445..2661
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            2662..2781
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            2782..3043
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            3044..3311
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3455
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            3456..3705
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            3706..3726
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            3727..3959
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            3960..4114
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            4115..4989
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            4990..5165
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            5166..5401
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            5402..5698
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            5699..7310
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            7311..7441
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     exon            7442..10978
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10950..10955
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /note="hexamer: AATAAA"
     polyA_site      10970
                     /gene="Tenm3"
                     /gene_synonym="2610100B16Rik; mKIAA1455; Odz1; Odz3;
                     Ten-m3"
                     /note="major polyA site"
ORIGIN      
        1 aagttctaag aagccggacc gatgtgcaca gagaaggaat gaaggaagta tggatgtgaa
       61 ggaacgcagg ccttactgct ccttgaccaa gagcagacgg gaaaaggaaa ggcgctatac
      121 aaactcgtcc gcggacaatg aggagtgtag ggtccccacg cagaagtcct atagttccag
      181 tgaaaccttg aaagctttcg atcatgattc ttcacggctg ctttatggaa acagagtaaa
      241 ggatttggtc cacagagaag ccgacgagta tactagacaa ggacagaatt ttaccctaag
      301 gcagttagga gtgtgtgaat ccgcaactcg aagaggagtg gcattctgtg cggaaatggg
      361 gctccctcac agaggttact ccatcagtgc agggtcagat gcggatacgg aaaacgaagc
      421 agtgatgtcc cctgagcatg ccatgagact ttggggcagg ggggtcaaat cgggccgcag
      481 ttcctgcctg tcaagccggt ccaactccgc cctcaccctg acagacacgg agcacgagaa
      541 caggtcggac agtgagagcg agcaaccttc aaacaaccca gggcaaccca ccctgcagcc
      601 tttgccgcca tcccacaagc agcacccggc gcagcatcac ccgtccatca cttccctcaa
      661 tagaaactcc ctgaccaata gaaggaacca gagtccggcc ccgccggctg ctttgcccgc
      721 cgagctgcaa accacacccg agtccgtcca gctgcaggac agctgggtcc ttggcagtaa
      781 tgtaccactg gaaagcaggc atttcctatt caaaacaggg acagggacga cgccactgtt
      841 cagtacggca accccgggat acacaatggc atctggctct gtttattctc cgcctacccg
      901 gccacttcct agaaacaccc tatcaagaag tgcttttaaa ttcaagaagt cttcaaagta
      961 ctgcagctgg aggtgcaccg cactgtgtgc tgtaggggtc tcagtgctcc tggccattct
     1021 cctctcctat tttatagcaa tgcatctatt tggcctcaac tggcacttac agcagacgga
     1081 aaatgacaca ttcgagaatg gaaaagtgaa ttctgacacc gtgccaacaa acactgtatc
     1141 gttaccttct ggcgacaatg gaaaattagg tggatttaca catgaaaata acaccataga
     1201 ttccggagaa cttgatattg gccggagagc aattcaagag gttccccccg ggatcttctg
     1261 gagatcgcag ctctttattg atcagccaca gtttcttaag ttcaacatct ctcttcagaa
     1321 ggatgcattg atcggagtgt acggccggaa gggcttaccg ccttcccata ctcagtacga
     1381 ctttgtggaa ctactggatg gtagcaggtt aattgcgaga gagcagcgga acctggtgga
     1441 gtccgaaaga gccgggcggc aggcgagatc tgtcagcctg cacgaagctg gcttcatcca
     1501 gtacttggat tctggaatct ggcatctggc tttttataac gacgggaaaa acccagagca
     1561 ggtctccttt aacacgatcg ttatagagtc tgtggtggaa tgcccccgaa attgccatgg
     1621 aaatggagag tgtgtttctg gaacttgcca ttgtttcccc gggtttctag gtccggattg
     1681 ttcaagagca gcctgtccgg tgctctgtag tggcaacggg caatactcca agggccgctg
     1741 cctgtgcttc agtggctgga agggcaccga gtgtgacgtg ccgacgaccc agtgcattga
     1801 cccgcagtgc gggggtcgtg ggatttgcat catgggctct tgcgcttgta actcgggata
     1861 caaaggagaa aactgtgagg aagcggactg tctagaccct ggatgttcta atcacggggt
     1921 gtgtatccat ggggaatgtc actgcaatcc aggctggggt ggcagcaact gtgaaatact
     1981 gaagactatg tgtgcagacc agtgctcagg ccacgggact taccttcaag aaagcggctc
     2041 ctgcacttgc gacccaaatt ggactggccc cgactgctca aatgaaatat gttcagtgga
     2101 ctgcggctca cacggcgtct gcatgggggg ctcctgtcgc tgtgaagaag gctggaccgg
     2161 cccggcgtgt aatcagagag cttgccaccc tcgctgtgct gagcacggga cgtgcaagga
     2221 cggcaagtgc gagtgcagcc aaggatggaa cggagagcac tgcacaattg ctcactattt
     2281 ggataagata gttaaagagg gttgccccgg cttgtgcaac agcaatggga gatgcacact
     2341 ggaccaaaac ggctggcact gcgtttgcca gccagggtgg agaggagcag gctgtgacgt
     2401 agccatggag accctctgta cagacagcaa agacaacgaa ggagacggac tcattgactg
     2461 catggatcct gattgctgcc tccagagctc ctgccaaaac cagccctact gtcgtggctt
     2521 gcctgatcct caggatatca ttagccaaag ccttcagaca ccatctcagc aagctgccaa
     2581 gtccttctat gaccgaatca gtttcctgat tggatcggat agcacccacg tgctccctgg
     2641 agaaagtccg ttcaataaga gtcttgcgtc cgtcatcaga ggccaagtac taacagctga
     2701 tggaacccca cttattggcg tcaacgtgtc gtttttacac tactcggaat atggatatac
     2761 cattacccgc caggatggaa tgtttgactt ggtggcaaat ggtggcgctt ctctgacttt
     2821 ggtatttgag cgttccccat tcctcactca gtaccacact gtgtggattc cctggaatgt
     2881 cttttatgtg atggataccc ttgtcatgaa gaaagaggag aacgacattc ccagctgtga
     2941 cctcagtggc tttgtgaggc caagtcccat cattgtgtct tcaccgttat ccaccttctt
     3001 caggtcttcc cctgaggaca gccccatcat ccccgagaca caggtcctgc atgaagaaac
     3061 cacaattcca ggaacagatt tgaaactttc ctacctgagt tccagagcgg cagggtacaa
     3121 gtcagttctt aagattacca tgacccaggc cgtcataccg tttaacctca tgaaggtcca
     3181 tctgatggtg gccgtggttg ggagactctt ccagaagtgg tttcctgcct cgccaaactt
     3241 ggcctacacg ttcatctggg ataagacgga cgcatataat cagaaagtct acggcttgtc
     3301 agaggcagtt gtgtccgtcg gatacgagta cgagtcgtgc ttggacctga ctctctggga
     3361 aaagaggact gccgttttgc aaggctatga gttggatgct tcgaacatgg gcggctggac
     3421 gttggacaag caccatgtac tggacgttca gaacggtata ctatacaaag gaaatggaga
     3481 aaatcagttc atctctcagc agcctccggt ggtcagcagc atcatgggta atggtcggag
     3541 gcgtagcatc tcatgcccaa gttgcaatgg tcaagctgac gggaacaaac tcctggcacc
     3601 cgtggcgctt gcctgtggga tcgacggcag tctatacgta ggggatttca attacgtccg
     3661 gcggatattc ccgtctggga atgtgacaag tgttttagaa ctaagaaata aagattttag
     3721 acatagtagc aacccagctc acagatacta cctggctacg gacccagtca ccggagattt
     3781 gtacgtctct gatactaaca cccgcagaat ctatcggccg aaatcactca cgggagccaa
     3841 agacctgact aaaaacgctg aagtggtggc agggaccggg gaacagtgcc ttccctttga
     3901 cgaggccagg tgtggggatg gaggcaaggc tgtggaagca acgctcatga gtcccaaagg
     3961 aatggcaatc gataagaacg gactgatcta ctttgttgat ggaaccatga tcagaaaggt
     4021 tgatcaaaat ggaatcatat caactctcct gggctccaac gacctcacgt cagctcgacc
     4081 tttaacctgt gatactagca tgcatatcag ccaggtgcgt ctggaatggc ccactgacct
     4141 cgcgatcaac cccatggata actccatcta cgtcctggat aataacgtag ttttacagat
     4201 cactgaaaac cgtcaggtcc gcatcgctgc cgggcggccc atgcactgtc aggtccctgg
     4261 agtggaatac ccggtgggga agcacgcggt tcagaccacc ctggagtcag ccacggccat
     4321 tgctgtgtcc tacagcgggg tcctttacat cacggaaact gatgagaaga agatcaaccg
     4381 aataaggcag gtcacgacag acggggagat ctccttagtg gctgggatac cttcggaatg
     4441 tgactgcaag aacgacgcca actgtgactg ctaccaaagc ggagacggct acgccaaaga
     4501 tgccaaactc aatgcgccgt cctccctggc cgcctcgcca gatggcactc tgtacattgc
     4561 agatctggga aatatcagga tccgggccgt ttcgaagaat aaacctttac tgaactcaat
     4621 gaacttttac gaagttgcct ctccaactga tcaagagctc tacatctttg acatcaacgg
     4681 tactcaccag tacaccgtga gcctggtcac gggtgactac ctatataatt ttagttacag
     4741 caatgacaat gacgtcaccg ctgtaactga cagcaatggc aacaccctcc gaatccgaag
     4801 ggatccgaat cggatgccgg tgcgggtggt gtctcctgat aaccaggtga tatggttgac
     4861 cataggcacc aacgggtgtc tgaaaagcat gaccgctcag ggcctggaac tggttttgtt
     4921 tacttaccat ggcaacagtg ggcttttagc caccaaaagt gacgaaactg gatggacaac
     4981 attttttgac tatgacagtg aaggtcgcct gacgaatgtt accttcccca ctggggtggt
     5041 tacaaacctg cacggggaca tggacaaggc tatcacggtg gacatcgagt catccagcag
     5101 agaggaagat gtcagcatca cttcgaactt gtcctccatc gattccttct acaccatggt
     5161 ccaagaccag ttaagaaaca gttaccagat tgggtatgat ggctccctta gaatcttcta
     5221 tgccagtggt ctggactctc actaccagac agagccccac gttctggctg gcacggcgaa
     5281 tcccacagta gccaaaagaa acatgactct tcccggtgag aacgggcaga atctggtgga
     5341 gtggagattc cgaaaagaac aagcccaggg caaagtcaac gtattcggcc ggaagctcag
     5401 ggtcaatggg cgcaacctac tctcagtgga ctttgatcgg accaccaaga cggaaaagat
     5461 ctatgatgac caccggaaat ttctcctgag gatcgcttac gacacgtcgg ggcacccgac
     5521 tctctggctg ccgagtagca agctaatggc agtgaacgtc acctactcat ccaccggtca
     5581 aattgccagc atccagagag ggaccacgag cgaaaaggtg gactatgaca gccaggggag
     5641 gatcgtatct cgggtctttg ccgatgggaa aacatggagt tacacgtact tggaaaagtc
     5701 catggttctt ctgctccata gccagcggca gtacatcttc gaatacgaca tgtgggaccg
     5761 cctgtccgcc atcaccatgc ccagtgtggc tcgccacacc atgcagacca tccggtccat
     5821 tggctactac cgcaacatct acaatccccc agaaagcaat gcctctatca tcaccgacta
     5881 caacgaggaa gggctgcttc tgcaaacagc tttcctggga acgagtcgga gggtcttatt
     5941 caagtataga aggcagacca ggctatcaga aattttatac gacagcacaa gagtcagttt
     6001 tacctacgac gaaacagcgg gagtcctgaa aacagtaaac cttcagagtg atggttttat
     6061 ttgcaccatt agatacaggc aaattggtcc cctgattgac agacagattt tccgcttcag
     6121 cgaggatgga atggtaaatg cgagatttga ctatagctac gacaacagct ttcgagtgac
     6181 cagcatgcag ggtgtcatca atgaaacacc actgcccatt gatctatacc agtttgatga
     6241 catctctggc aaagtcgagc agtttggaaa attcggagtg atatactacg acatcaacca
     6301 aatcatttcc acggccgtga tgacttatac aaagcacttt gatgctcatg ggcgcatcaa
     6361 ggagatccaa tatgagatat ttaggtcact catgtactgg attacaattc aatatgataa
     6421 tatgggccgg gtaaccaaga gagagattaa aattgggcct tttgccaaca ctaccaaata
     6481 cgcgtacgag tacgacgtcg atggacagct ccaaacagtt tacctaaacg aaaagatcat
     6541 gtggcggtac aactacgacc taaatggaaa cctccacttg ctcaacccca gcagcagcgc
     6601 ccgcctgacc cctctgcgct atgacctgcg cgacagaatc acccgcctgg gcgatgttca
     6661 gtaccggctg gatgaagatg gtttcctgcg tcagaggggc actgaaattt ttgaatacag
     6721 ctccaaaggg cttctgactc gagtctacag taaaggcagt ggctggacag tgatctatcg
     6781 gtacgacggc ctgggaagac gtgtttctag caaaaccagc ctgggacagc accttcagtt
     6841 tttctacgcc gacctgacat accccacgag aattactcac gtctacaacc attccagttc
     6901 agaaatcacc tccctgtact atgacctcca aggacatctc ttcgccatgg agatcagcag
     6961 tggggatgag ttctacatcg cctcggacaa cacggggaca ccgctggctg ttttcagcag
     7021 caacgggctc atgctgaaac agatccagta cactgcctat ggtgagatct actttgactc
     7081 caacgtcgac tttcagctgg taattggatt ccacgggggc ttgtatgacc cgctcaccaa
     7141 actaatccac tttggagaaa gagattatga cattttggcg ggaagatgga ccacaccgga
     7201 cattgaaatc tggaaaagga tcggaaagga ccctgctcct tttaacctgt atatgtttcg
     7261 gaataacaac cccgcgagca aaatccatga tgtgaaagat tacatcacgg atgttaacag
     7321 ctggctggtg acgtttggct tccatctgca caatgctatt cctggattcc ctgttcccaa
     7381 atttgattta actgagcctt cctatgagct tgtgaagagt caacagtggg aagatgtgcc
     7441 gcccatcttt ggagttcagc agcaagtggc aaggcaagcc aaggccttct tgtccctggg
     7501 gaagatggcc gaggtgcagg tgagccgacg caaagctggc gccgagcagt cgtggctgtg
     7561 gttcgccacg gtcaagtcgc tcatcggcaa gggcgtcatg ctggccgtga gccaaggccg
     7621 cgtgcagacc aacgtgctca acatcgccaa cgaggactgc atcaaggtgg cggcggtgct
     7681 caacaacgcc ttctacctgg agaacctgca cttcaccatc gagggcaagg acacacacta
     7741 cttcatcaag accaccacac ccgagagcga cctgggcaca ctgcggctga cgagcggtcg
     7801 caaggccctg gagaacggga tcaacgtgac cgtgtctcag tccaccacgg tggtgaacgg
     7861 caggactcgc aggttcgccg acgtggagat gcagttcggt gccctggcac tgcatgtgcg
     7921 ctatggcatg acgctggacg aggagaaggc gcgcattctg gagcaggcgc gccagcgcgc
     7981 gctcgcccgg gcgtgggcac gggagcagca gcgcgtgcgc gacggcgagg agggtgcgcg
     8041 cctctggacg gagggtgaga aacggcagct gctgagcgct ggcaaggtgc agggctacga
     8101 tgggtactac gtactgtcgg tggagcagta ccccgagctg gctgacagtg ccaacaacat
     8161 ccagttcttg cgacaaagtg agatcggcaa gaggtaaccc ccgggccacc cctgtgcaga
     8221 ttctcctgta gcacaatcca aaccggactc tccaaagagc cttccaaaat gacactgctc
     8281 tgcagacaga cacatcgcag atacacacgc aacacaaacc agaaacaaag acaacttttt
     8341 ttttttttct gaatgacctt aaaggtgatc ggctttaaag aatatgttta catacgcata
     8401 tcgctgcact caattggact ggaagtatga gaaaggaaaa aaaagcatta aaaaaggcaa
     8461 cgttttgcca tgacccctct gtaccttcga ggcactgtat ttaacaaagg ttttaaaaag
     8521 gaaaaaaaaa tgcgtacaat gtttccagat attactgaat tgtcgacctt tgcttacagg
     8581 aagtaatctc tacttaggat gtgatatata tagatctgtt cattttaaaa tgtggggcaa
     8641 agttactgtt tatagaaccc aactgctttc ccgtgctgct ttgtaaaagg acactggcac
     8701 aagggacgtc tgcttcggcg gggatttaat aatggatttt actaacatgg cttgccctgg
     8761 gagggaaaaa ctgacgaata gaatccttgt cactgataag caaaggaaac cctgattttt
     8821 ttgtaaatta tgtgagacaa gttgtttatg gatttttata tgaattacaa tttactgtac
     8881 atcaaatatt agtctcagag gagttaattt atgtaaagtg tttaaaaagt ttatacttaa
     8941 aaataaaatg ataaaaacat gtgaactgtg tgattttttt aaaaaggatt gcaccttttg
     9001 ttatctgtta taactgtaca gtataactta ttatattgta gaggtataac aacttatgcc
     9061 tatcatgtcc agaagtgtta atatttttgt attaggttga aaaaaataaa acaatgcgct
     9121 actttctatc acttagatag ataggacctg tgcagtcctc agcgggtggc taatcagaga
     9181 acttcttttc gtccttctct ttcttaccaa gccactggcc tcaaccatta ccaaccaaga
     9241 ggcccagttg acatccaagg ctggcgagat gttatggagg gtgtggggga ggggagacaa
     9301 agagaaaaga acccaagaga agaggctctc tgaccctctc taggccctaa aagtcaagcc
     9361 gacttccaga acttttcata ctatattgtt gtccctcgat gctccacttt gtgatggagg
     9421 aaagagacca caatctgatg ctcgggaact tctgtgggga gggaaggact tgatgtcatg
     9481 gtaaccatga acatgtatct taatgtctag gagagatagc aataaccgag cagtagtgag
     9541 ccaggcgagg ggaccaacca gtcaaggtca ctctctgtga ggcttggagt tggaccctta
     9601 cgtcagcgtt agcaggtggg atcaaaaccg gaagttaagc tcctgtaagc ctacatggcc
     9661 caaccatcat agagcatggt ttgagtggca gcctgtgctg gccaggggta gcctggggta
     9721 ctgggtggag taggaaggaa actgacatca gtgcccgccc cccactgaaa gcttggggtt
     9781 ccactgtgtg cacttctgtg ccaacccggc cactctgaag aatctttcgt gaacactgaa
     9841 ttcagccaca aaagtatttt tagaaaagat ttctcagttc attgagctat agtacacact
     9901 gttttcctct ctgtataatg gtgacaaata tagcaagtga acatgtcgta aatataaagg
     9961 ttcaagtgat gtattgaaaa taattttcta actgctttgt atgtatcaca tactctaaat
    10021 tgcacagtag gcgtgtttat taaacagatt ggctgggaaa gttttgaaat agtactgaat
    10081 ttacagtctc agtgctattc ctgttgctgt gtatgtggta ggttataccg aagtaactaa
    10141 tcttctaatg aatgctgata ttttattaga atgaaagcac agattagcat taatattttt
    10201 tatcctggaa atcctttggc aagtactggg cagcccaaat ttagaaaact atgagatttc
    10261 aaaccacgta aacatggttc tgttggacat tttatttttt aactgttaac ttaggtgttc
    10321 gcagttctgt tgaatgggac ttctgcagga ctgtatttag catgctgtaa gtactttggg
    10381 gtgaaatagg ctccgagtct aaattctcag aaatgtctgt gatgtattga ccatgaatag
    10441 cgtgtaccac atgacagaag tgaaattaca ctcttaaccc cttctcaacg tggactggtc
    10501 tttacagggg caccaataaa tgacagatct ggagagtctc ctggtgctta ttttagaagt
    10561 caaatcaacc caattagtat cttgttagta gatataatga gcctatttct ttctaaaaag
    10621 gcttgtggtc tggacgtgct tttacaagaa atagtgacct tggggaatat gtaaacaaga
    10681 gatctttttc taagagtttg gggggaggtt gggggacctg tataatgaca aaaaaaaatt
    10741 agcttacaac aatgacaaca acaaaaaaca aaaacaaaag aaattgatat tcaaagtatt
    10801 ttaggcaaag ccagtcaaaa tgctttcatg atattttgag atgtaaattt ttgtctgatt
    10861 tgtattgttc ttttcgtttg ccttcttaac tttatatgtg acctgaattt tccataactt
    10921 gatgactata gattgcatct aggcattcca ataaaagcca acccaatgtg tgtgcgtt
//
