LOCUS       NP_035985               2731 aa            linear   ROD 27-APR-2025
DEFINITION  teneurin-1 [Mus musculus].
ACCESSION   NP_035985 XP_203220
VERSION     NP_035985.2
DBSOURCE    REFSEQ: accession NM_011855.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 2731)
  AUTHORS   Liakath-Ali,K., Refaee,R. and Sudhof,T.C.
  TITLE     Cartography of teneurin and latrophilin expression reveals
            spatiotemporal axis heterogeneity in the mouse hippocampus during
            development
  JOURNAL   PLoS Biol 22 (5), e3002599 (2024)
   PUBMED   38713721
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 2731)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (residues 1 to 2731)
  AUTHORS   Song,W., Li,Q., Wang,T., Li,Y., Fan,T., Zhang,J., Wang,Q., Pan,J.,
            Dong,Q., Sun,Z.S. and Wang,Y.
  TITLE     Putative complement control protein CSMD3 dysfunction impairs
            synaptogenesis and induces neurodevelopmental disorders
  JOURNAL   Brain Behav Immun 102, 237-250 (2022)
   PUBMED   35245678
REFERENCE   4  (residues 1 to 2731)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 2731)
  AUTHORS   Cortes-Montero,E., Rodriguez-Munoz,M., Sanchez-Blazquez,P. and
            Garzon,J.
  TITLE     The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and
            Calmodulin-Regulated Cysteine SUMO Protease
  JOURNAL   Antioxid Redox Signal 31 (7), 503-520 (2019)
   PUBMED   31088288
REFERENCE   6  (residues 1 to 2731)
  AUTHORS   Wang,L., Rotzinger,S., Al Chawaf,A., Elias,C.F.,
            Barsyte-Lovejoy,D., Qian,X., Wang,N.C., De Cristofaro,A.,
            Belsham,D., Bittencourt,J.C., Vaccarino,F. and Lovejoy,D.A.
  TITLE     Teneurin proteins possess a carboxy terminal sequence with
            neuromodulatory activity
  JOURNAL   Brain Res Mol Brain Res 133 (2), 253-265 (2005)
   PUBMED   15710242
REFERENCE   7  (residues 1 to 2731)
  AUTHORS   Zhou,X.H., Brandau,O., Feng,K., Oohashi,T., Ninomiya,Y., Rauch,U.
            and Fassler,R.
  TITLE     The murine Ten-m/Odz genes show distinct but overlapping expression
            patterns during development and in adult brain
  JOURNAL   Gene Expr Patterns 3 (4), 397-405 (2003)
   PUBMED   12915301
REFERENCE   8  (residues 1 to 2731)
  AUTHORS   Feng,K., Zhou,X.H., Oohashi,T., Morgelin,M., Lustig,A.,
            Hirakawa,S., Ninomiya,Y., Engel,J., Rauch,U. and Fassler,R.
  TITLE     All four members of the Ten-m/Odz family of transmembrane proteins
            form dimers
  JOURNAL   J Biol Chem 277 (29), 26128-26135 (2002)
   PUBMED   12000766
REFERENCE   9  (residues 1 to 2731)
  AUTHORS   Minet,A.D., Rubin,B.P., Tucker,R.P., Baumgartner,S. and
            Chiquet-Ehrismann,R.
  TITLE     Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene
            ten-m, is a neuronal protein with a novel type of heparin-binding
            domain
  JOURNAL   J Cell Sci 112 (Pt 12), 2019-2032 (1999)
   PUBMED   10341219
REFERENCE   10 (residues 1 to 2731)
  AUTHORS   Oohashi,T., Zhou,X.H., Feng,K., Richter,B., Morgelin,M.,
            Perez,M.T., Su,W.D., Chiquet-Ehrismann,R., Rauch,U. and Fassler,R.
  TITLE     Mouse ten-m/Odz is a new family of dimeric type II transmembrane
            proteins expressed in many tissues
  JOURNAL   J Cell Biol 145 (3), 563-577 (1999)
   PUBMED   10225957
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY729750.1, BC138860.1 and AL831716.7.
            
            On or before Sep 3, 2004 this sequence version replaced
            XP_203220.3, NP_035985.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB025410.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 23.21 cM"
     Protein         1..2731
                     /product="teneurin-1"
                     /note="tenascin-M1; protein Odd Oz/ten-m homolog 1"
                     /calculated_mol_wt=305666
     Region          1..72
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          23..317
                     /region_name="Ten_N"
                     /note="Teneurin Intracellular Region; pfam06484"
                     /db_xref="CDD:461932"
     Region          62..65
                     /region_name="Nuclear localization signal (NLS).
                     /evidence=ECO:0000250"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            105
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            109
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            116
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          175..241
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          290..297
                     /region_name="Required for interaction with SORBS1 (Ten-1
                     ICD form). /evidence=ECO:0000250"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            325..345
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            432
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          529..720
                     /region_name="DUF5885"
                     /note="Family of unknown function (DUF5885); pfam19232"
                     /db_xref="CDD:437064"
     Region          711..754
                     /region_name="DSL"
                     /note="Delta serrate ligand; cl19567"
                     /db_xref="CDD:473190"
     Region          802..827
                     /region_name="acid_disulf_rpt"
                     /note="acidic double-disulfide repeat; NF033662"
                     /db_xref="CDD:411265"
     Site            904
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1083
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1193..1218
                     /region_name="NHL 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1196..1527
                     /region_name="NHL"
                     /note="NHL repeat unit of beta-propeller proteins;
                     cl18310"
                     /db_xref="CDD:302697"
     Region          1196..1235
                     /region_name="NHL repeat"
                     /note="NHL repeat [structural motif]"
                     /db_xref="CDD:271323"
     Region          1247..1290
                     /region_name="NHL repeat"
                     /note="NHL repeat [structural motif]"
                     /db_xref="CDD:271323"
     Region          1298..1342
                     /region_name="NHL 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1314..1352
                     /region_name="NHL repeat"
                     /note="NHL repeat [structural motif]"
                     /db_xref="CDD:271323"
     Region          1357..1408
                     /region_name="NHL 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1370..1409
                     /region_name="NHL repeat"
                     /note="NHL repeat [structural motif]"
                     /db_xref="CDD:271323"
     Region          1420..1464
                     /region_name="NHL 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1433..1466
                     /region_name="NHL repeat"
                     /note="NHL repeat [structural motif]"
                     /db_xref="CDD:271323"
     Region          1487..1530
                     /region_name="NHL 5"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1490..2423
                     /region_name="RhsA"
                     /note="Uncharacterized conserved protein RhaS, contains 28
                     RHS repeats [General function prediction only]; COG3209"
                     /db_xref="CDD:442442"
     Region          1501..1527
                     /region_name="NHL repeat"
                     /note="NHL repeat [structural motif]"
                     /db_xref="CDD:271323"
     Region          1540..1559
                     /region_name="YD 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1556
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1573
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1576..1596
                     /region_name="YD 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1614..1638
                     /region_name="YD 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1639..1660
                     /region_name="YD 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1661..1681
                     /region_name="YD 5"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1669
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1705
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1743
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1763
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1787
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            1848
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1851..1870
                     /region_name="YD 6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1871..1891
                     /region_name="YD 7"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1892..1910
                     /region_name="YD 8"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1911..1931
                     /region_name="YD 9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1939..1955
                     /region_name="YD 10"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1956..1975
                     /region_name="YD 11"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1976..1995
                     /region_name="YD 12"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          1998..2018
                     /region_name="YD 13"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2021..2041
                     /region_name="YD 14"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2091..2111
                     /region_name="YD 15"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2119..2139
                     /region_name="YD 16"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            2151
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2159..2179
                     /region_name="YD 17"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2180..2200
                     /region_name="YD 18"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2202..2222
                     /region_name="YD 19"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2234..2254
                     /region_name="YD 20"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2256..2276
                     /region_name="YD 21"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            2291
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2302..2319
                     /region_name="YD 22"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2320..2343
                     /region_name="YD 23"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            2586
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9UKZ4; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            2601..2602
                     /site_type="cleavage"
                     /note="Cleavage. /evidence=ECO:0000305; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Site            2608
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q9WTS4.1)"
     Region          2647..2724
                     /region_name="Tox-GHH"
                     /note="GHH signature containing HNH/Endo VII superfamily
                     nuclease toxin; pfam15636"
                     /db_xref="CDD:464783"
     CDS             1..2731
                     /gene="Tenm1"
                     /gene_synonym="Odz1; Odz2; TCAP-1; ten-1; Ten-m1"
                     /coded_by="NM_011855.4:94..8289"
                     /db_xref="CCDS:CCDS40953.1"
                     /db_xref="GeneID:23963"
                     /db_xref="MGI:MGI:1345185"
ORIGIN      
        1 meqtdckpyq plskvkhemd laytsssdes edgrkprqsf nsretlheyn qelrrnynsq
       61 srkrkdveks tqeiefcetp ptlcsgyhtd mhsvsrhgyq lemgsdvdte tegaaspdha
      121 lrmwirgmks ehssclssra nsalsltdtd herksdgeng fkfspvccdm eapadsaqdm
      181 qssphnqftf rplppppppp hactcarkpp ptvdslqrrs mttrsqpspa apapptstqd
      241 svhlhnswvl nsnipletrh flfkhgsgss aifsaasqny pltsntvysp pprplprstf
      301 srpaftfnkp yrccnwkcta lsataitvtl alllayviav hlfgltwqlq pvgqiyangi
      361 sngnpgtesm dttyspiggr vsdksekkvf qkgraidtge vdigaqvmqt ippglfwrfq
      421 itihhpiylk fnislakdsl lgiygrrnip pthtqfdfvk lmdgkqlvkq dskssddiqh
      481 sprnliltsl qetgfieymd qgpwylafyn dgkkmeqvfv lttaieimdd cstncngnge
      541 cisghchcfp gflgpdcard scpvlcggng eyekghcvcr ngwkgpecdv peeqcidptc
      601 fghgtcimgv cicvpgykge iceeedcldp mcsshgicvk gechcstgwg gvncetplpi
      661 cqeqcsghgt flldtgvcsc dpkwtgsdcs telctmecgs hgvcsrgicq ceegwvgptc
      721 eerschshca ehgqckdgkc ecspgwegdh ctiahyldav rdgcpglcfg ngrctldqng
      781 whcvcqvgws gtgcnivmem lcgdnldndg dgltdcvdpd ccqqsncyvs plcqgspdpl
      841 dliqqsqplf sqhtsrlfyd rikfligkds thvvpqdisf dsrracvirg qvvavdgtpl
      901 vgvnvsflhh sdygftisrq dgsfdlvaig gisvvlifdr spflsekrtl wlpwnqfivv
      961 ekvimqriva dapscdisnf ispnpivlps pltsfggscp ergtivpelq vvqeeipips
     1021 sfvrlsylss rtpgyktllr illthstipv gmikvhltvs vegrltqkwf paainlvytf
     1081 awnktdiygq kvwglaealv svgyeyemcp efilweqrtv vlqgfemdas nlggwslnkh
     1141 hifnpqsgii hkgngenmfi sqqppviati mgnghqrsva ctncngpahn nklfapvala
     1201 sgpdgsvyvg dfnfvrrifp sgnsvsilel rnrdtrhsts pahkyylamd pmseslylsd
     1261 tntrkvyklk slvetkdlsk nfevvagtgd qclpfdqshc gdggkaseas lnsprgitvd
     1321 rhgfiyfvdg tmirridena vittvigsng ltstqplscd sgmditqvrl ewptdlavnp
     1381 mdnslyvldn nivlqisenr rvriiagrpi hcqvpgidhf lvskvaihst lesaraisvs
     1441 hsgllfiaet derkvnriqq vttngeisii agaptdcdck idpncdcfsg dggyakdakm
     1501 kapsslavsp dgtlyvadlg nvrirtiskn qahlndmnly eiaspadqel yqftvngthl
     1561 htmnlitrdy vynftynaeg dlgaitssng nsvhirrdag gmplwlvvpg gqvywltiss
     1621 ngvlkrvsaq gynlalmtyp gntgllatks nengwttvye ydpeghltna tfptgevssf
     1681 hsdlekltkv aldtsnrenv lmstnltats tiyilkqent qstyrvspdg slrvtfasgm
     1741 einlssephi lagavnptlg kcnislpgeh nanliewrqr keqnkgnvsa ferrlrahnr
     1801 nllsidfdhm trtgkiyddh rkftlrilyd qtgrpilwsp vsrynevnit yspsglvtfi
     1861 qrgtwnekme ydqsgkiisr twadgkiwsy tyleksvmll lhsqrryife ydqsdcllsv
     1921 tmpsmvrhsl qtmlsvgyyr niytppdsst sfiqdysrdg rllqtlhlgt grrvlykytk
     1981 qarlseilyd ttqvtltyee ssgviktihl mhdgfictir yrqtgpligr qifrfseegl
     2041 vnarfdysyn nfrvtsmqav inetplpidl yryvdvsgrt eqfgkfsvin ydlnqvittt
     2101 vmkhtkifna ngqvievqye ilkaiaywmt iqydnmgrmv icdirvgvda nitryfyeyd
     2161 adgqlqtvsv ndkiqwrysy dlngninlls hgnsarltpl rydlrdritr lgeiqykmde
     2221 dgflrqrgnd ifeynsngll qkaynkvsgw tvqyyydglg rrvasksslg qhlqffyadl
     2281 anpirvthly nhtsaeitsl yydlqghlia melssgeeyy vacdnmgtpl avfssrgqvi
     2341 keilytpygd iyhdtypdfe viigfhggly dfltklvhlg qrdydvvagr wttpnhhiwk
     2401 qlnllpkpfn lysfennypv gkiqdvakyt tdigtwlelf gfqlhnvlpg fpkpelenme
     2461 ltyellqlqt ktqewdpgkm ilgiqcelqk qlrnfisldq lpmtpqyneg rcleggkqpr
     2521 faavpsvfgk gikfaikegi vtadiigvan edsrrlaail nnahylenlh ftiegrdthy
     2581 fiklgsleed lvligntggr rilengvnvt vsqmtsvlng rtrrfadiql qhgalcfnir
     2641 ygttveeekn hvlemarqra vaqawtqeqr rlqegeegtr vwtegekqql lgtgrvqgyd
     2701 gyfvlsveqy lelsdsanni hfmrqseigr r
//
