LOCUS       NM_027630               1718 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus tektin like 1 (Tektl1), mRNA.
ACCESSION   NM_027630 XM_147407 XM_909809
VERSION     NM_027630.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Nguyen,T.T.T., Tokuhiro,K., Shimada,K., Wang,H., Mashiko,D.,
            Tonai,S., Kiyozumi,D. and Ikawa,M.
  TITLE     Gene-deficient mouse model established by CRISPR/Cas9 system
            reveals 15 reproductive organ-enriched genes dispensable for male
            fertility
  JOURNAL   Front Cell Dev Biol 12, 1411162 (2024)
   PUBMED   38835510
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  AUTHORS   Tai,L., Yin,G., Huang,X., Sun,F. and Zhu,Y.
  TITLE     In-cell structural insight into the stability of sperm microtubule
            doublet
  JOURNAL   Cell Discov 9 (1), 116 (2023)
   PUBMED   37989994
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1718)
  AUTHORS   Chen,Z., Shiozaki,M., Haas,K.M., Skinner,W.M., Zhao,S., Guo,C.,
            Polacco,B.J., Yu,Z., Krogan,N.J., Lishko,P.V., Kaake,R.M.,
            Vale,R.D. and Agard,D.A.
  TITLE     De novo protein identification in mammalian sperm using in situ
            cryoelectron tomography and AlphaFold2 docking
  JOURNAL   Cell 186 (23), 5041-5053 (2023)
   PUBMED   37865089
REFERENCE   4  (bases 1 to 1718)
  AUTHORS   Zhou,L., Liu,H., Liu,S., Yang,X., Dong,Y., Pan,Y., Xiao,Z.,
            Zheng,B., Sun,Y., Huang,P., Zhang,X., Hu,J., Sun,R., Feng,S.,
            Zhu,Y., Liu,M., Gui,M. and Wu,J.
  TITLE     Structures of sperm flagellar doublet microtubules expand the
            genetic spectrum of male infertility
  JOURNAL   Cell 186 (13), 2897-2910 (2023)
   PUBMED   37295417
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159747.8.
            
            On or before Jul 23, 2009 this sequence version replaced
            XM_909809.2, XM_147407.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016452.1, SRR5189685.90925.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-663               AC159747.8         72763-73425         c
            664-768             AC159747.8         70899-71003         c
            769-967             AC159747.8         69485-69683         c
            968-1134            AC159747.8         69004-69170         c
            1135-1230           AC159747.8         68801-68896         c
            1231-1344           AC159747.8         68609-68722         c
            1345-1718           AC159747.8         67282-67655         c
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..1718
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /note="tektin like 1"
                     /db_xref="GeneID:70976"
                     /db_xref="MGI:MGI:1918226"
     exon            1..663
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..1593
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /note="coiled-coil domain-containing protein 105;
                     coiled-coil domain containing 105"
                     /codon_start=1
                     /product="tektin-like protein 1"
                     /protein_id="NP_081906.1"
                     /db_xref="CCDS:CCDS48614.1"
                     /db_xref="GeneID:70976"
                     /db_xref="MGI:MGI:1918226"
                     /translation="MPVLLPSTDPGQDSRVGAPEWRQAAKATSRKAHLLTDRCGQEAV
                     TMWQPKDSVLDPNVAHHLGRAAYMEPWRFRVEMLKGGGTLEKPPPGEGVTLWKGKMKP
                     PAWYARLPLPMHRDARAQQTAEVVHAHARGARLTAARLGRAQHQINGQLRLLLRQREA
                     TDRRLSEVRKGLLINQQSVKLRGYRPKCEKIPDKADSLLVWEKKELKSMKRKMEKDME
                     ISEDLLKALASCRDTLDFYCQERLQAVELMNQPLDKVLEQAGRHSWVDITRPPTPRTQ
                     GLKTPPPDPIGTYTPACAKALFEAKRLLMESKDILTEMAKNEVDIQNQQQEISNRVCS
                     SLAQKMRETLELKERMTMTLGLMRGTIHRCMKFNQEMYVTRGIIKGPLLKRNLEAREK
                     LNRPLVRMYQRHVGTQLPEATRLAQGTDLLTRHNLHMEKNLKELRTTHDNLAWGLNCK
                     KIGHDVDYDVVRLRLRQRHPHVCYEQAQRLVNDWDPPTPARSQTNTASK"
     exon            664..768
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     exon            769..967
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1134
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1230
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1344
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1718
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1696..1701
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /note="hexamer: ATTAAA"
     polyA_site      1718
                     /gene="Tektl1"
                     /gene_synonym="4931413A09Rik; Ccdc105"
                     /note="major polyA site"
ORIGIN      
        1 cattctagcc accagtaaag agtggtgtgt ggttagggct gggtggaccc ctgtccattc
       61 tccgaggaga tcgcgggcac taaataagga accatgcctg tgttgctccc ttccaccgac
      121 ccgggccagg actcgcgcgt tggggctcca gaatggcgcc aggcggccaa ggccacgtct
      181 cgcaaggcac accttctgac cgatcgctgt gggcaggagg cggtgaccat gtggcagccc
      241 aaggacagtg tactggaccc gaacgtggca caccacctgg gccgcgccgc ctacatggaa
      301 ccctggcgct ttcgggtaga gatgctcaaa gggggcggca ccctggaaaa gccaccgccc
      361 ggagaaggcg tcaccctatg gaaagggaag atgaagcccc cggcctggta cgcgcgccta
      421 ccgctgccta tgcaccgcga cgcgcgtgcc cagcaaaccg ccgaggtggt gcacgcgcac
      481 gcacgcgggg cgcgcctcac cgccgcccgc ctgggccgcg cacagcacca gatcaatggg
      541 cagctgcggc tgctgctgcg ccagcgcgag gccactgacc gcaggctcag cgaggtgcgc
      601 aagggcctgc tcatcaatca gcagagcgtc aagttgcggg gctaccgacc taagtgtgag
      661 aagatcccag acaaggctga cagcttgctt gtctgggaga aaaaggaact gaagtccatg
      721 aagagaaaaa tggagaagga catggaaata tcggaggact tgctcaaggc tctggcctcc
      781 tgcagggaca ctctggactt ctactgtcag gaaaggctgc aagctgtgga actcatgaac
      841 cagccactgg acaaagttct ggagcaggct ggccgccact cgtgggtaga catcacccga
      901 cccccaactc ctcgaactca gggcttgaaa acgcctcctc ctgaccccat tggcacatat
      961 accccagcgt gtgctaaggc cttgtttgaa gccaagcgct tgttgatgga gtccaaagac
     1021 atcttaacag agatggcaaa gaatgaggtg gacattcaaa atcaacaaca ggagataagc
     1081 aaccgtgtat gctcctcgct ggcacagaag atgcgtgaga ccttggagtt gaaggaaaga
     1141 atgaccatga ctttggggct aatgaggggg actatccacc ggtgcatgaa attcaatcaa
     1201 gagatgtacg tcacgcgggg catcatcaag ggtcctctgt tgaaaaggaa cctggaggcg
     1261 cgagagaaac tgaacagacc cttggttcgc atgtatcaga gacacgtggg cacccagctc
     1321 cccgaggcta ctcgccttgc ccagggtact gacctgctga cccgccacaa cttgcacatg
     1381 gaaaagaatt taaaagagct ccgtacaaca cacgataacc tcgcctgggg cctcaactgc
     1441 aaaaagatag ggcacgatgt ggactacgat gtggtgcgtc tgcgcctacg ccagcgccac
     1501 ccgcacgtgt gctatgagca agcgcagcgc ctggtcaacg actgggaccc tcccacacca
     1561 gcgcgcagcc aaaccaatac cgcctccaag tgacctcagc ttgccttggt cttgtggggc
     1621 tggagcggat acccccagat acatggccct ccctctgact aaccttccct ccaaacgccc
     1681 tctatcagaa ctataattaa aatatattct cattatta
//
