LOCUS       NM_001291001            1764 bp    mRNA    linear   ROD 21-SEP-2024
DEFINITION  Mus musculus tektin 5 (Tekt5), mRNA.
ACCESSION   NM_001291001 XM_006522535
VERSION     NM_001291001.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1764)
  AUTHORS   Tai,L., Yin,G., Huang,X., Sun,F. and Zhu,Y.
  TITLE     In-cell structural insight into the stability of sperm microtubule
            doublet
  JOURNAL   Cell Discov 9 (1), 116 (2023)
   PUBMED   37989994
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1764)
  AUTHORS   Chen,Z., Shiozaki,M., Haas,K.M., Skinner,W.M., Zhao,S., Guo,C.,
            Polacco,B.J., Yu,Z., Krogan,N.J., Lishko,P.V., Kaake,R.M.,
            Vale,R.D. and Agard,D.A.
  TITLE     De novo protein identification in mammalian sperm using in situ
            cryoelectron tomography and AlphaFold2 docking
  JOURNAL   Cell 186 (23), 5041-5053 (2023)
   PUBMED   37865089
REFERENCE   4  (bases 1 to 1764)
  AUTHORS   Zhou,L., Liu,H., Liu,S., Yang,X., Dong,Y., Pan,Y., Xiao,Z.,
            Zheng,B., Sun,Y., Huang,P., Zhang,X., Hu,J., Sun,R., Feng,S.,
            Zhu,Y., Liu,M., Gui,M. and Wu,J.
  TITLE     Structures of sperm flagellar doublet microtubules expand the
            genetic spectrum of male infertility
  JOURNAL   Cell 186 (13), 2897-2910 (2023)
   PUBMED   37295417
REFERENCE   5  (bases 1 to 1764)
  AUTHORS   Aoki,N. and Matsui,Y.
  TITLE     Comprehensive Analysis of Mouse Cancer/Testis Antigen Functions in
            Cancer Cells and Roles of TEKT5 in Cancer Cells and Testicular Germ
            Cells
  JOURNAL   Mol Cell Biol 39 (17), e00154-19 (2019)
   PUBMED   31208979
  REMARK    GeneRIF: Results showed that TEKT5 controls tubulin stability to
            enhance the growth and survival of cancer cells and to promote
            sperm morphogenesis.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1764)
  AUTHORS   Cao,W., Ijiri,T.W., Huang,A.P. and Gerton,G.L.
  TITLE     Characterization of a novel tektin member, TEKT5, in mouse sperm
  JOURNAL   J Androl 32 (1), 55-69 (2011)
   PUBMED   20378928
  REMARK    GeneRIF: TEKT5 protein was highly expressed in mouse spermatids and
            was localized in the flagellar accessory structures.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154311.2.
            
            On Jun 17, 2019 this sequence version replaced NM_001291001.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GQ292766.1, SRR7652917.1152303.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-603               AC154311.2         8661-9263
            604-687             AC154311.2         16878-16961
            688-758             AC154311.2         17983-18053
            759-902             AC154311.2         21183-21326
            903-1125            AC154311.2         24997-25219
            1126-1280           AC154311.2         42704-42858
            1281-1764           AC154311.2         45681-46164
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 5.58 cM"
     gene            1..1764
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /note="tektin 5"
                     /db_xref="GeneID:70426"
                     /db_xref="MGI:MGI:1917676"
     exon            1..603
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            604..687
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            688..758
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            759..902
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1125
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1280
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1764
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1742..1747
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1748
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /note="major polyA site"
     polyA_site      1764
                     /gene="Tekt5"
                     /gene_synonym="3300001K11Rik"
                     /note="major polyA site"
ORIGIN      
        1 gggtaaagtt ttccccggtg gggctgatgg ggaaagatgg aatttcttgg aaccactcag
       61 acagcgagtt tctgtggccc caagaaaggc tgtggcttgc aggcgctgcc ccctgctggg
      121 caggaacctg tggtacagga gtgctaccaa ccctttcacc tgcccggata ccgctacctg
      181 aacgcgtgga gacccagcgt cttccacaag atcgccacct cccagacaat ccccgaggaa
      241 tgctcaggca tccggcggcc gcccaccatc ctgccctcgc tccgctccgc gctcttctgt
      301 cgctacaccc caagggactg ggaccgctcc aatgatctgc agatcaggaa tgcagaggcc
      361 tcgcggctct gggccagccg gctgacaggc gactcgctgc ggatcatgca ggataaggac
      421 cagctgatac accagatgca ggagggaacc tcccggaact tgggccagag gctatccgac
      481 ctcggtttct ggaagtccga gttgtgctat gagctggaca ggcttctgac ggagaacagc
      541 agcatggaca ccctcaagag gcgcttggag tgcgctgctg aggaggtgaa ctgtcccttg
      601 caggtggccc tggagtgtct gtacaatcgg gagaaaagga tcgggattga cctggtccat
      661 gacaacgtgg agaaaaacct tatccgggaa gtagatttac taaaatgttg ccaagatcag
      721 atgagaaaat tagctaaacg aattgatttc cagattcgag ataaccggga tgctcagcac
      781 tccctagagc gggatattga agacaagagc tctgcacagt atattgacga gaattgtttt
      841 aacctaagaa gcacgtctga ctccatcagc ttcttccacg gcgtggagaa gtttgacgga
      901 acggtctcca ttcctgaaac ctgggccaag ttcagcaatg acaacatcag acatgctcag
      961 aacatgcggg ctaactccat ccggctgcgg gaagaggcag agcacctgtt tgagaccttg
     1021 tcggaccaga tgtggaagca gttcaccaac accaacctag ccttcaacgc tcgcatctct
     1081 gaggagacag atgtgaagaa caagctgcag acacagctgg ctaagatact gcaggagatc
     1141 ttccaggcag aaaacaccat catgttgctg gagagggcca ttgtggccaa ggaataccca
     1201 ctgaagatgg cccagaccat gctagcatgc aggacccgac ggcccaatgt ggaactctgc
     1261 agggatgtgc cacagttcag gctcgtgaat gaggtcttca ccatagacga cactctacag
     1321 acgctcaagc tgaggcttcg ggagacgcaa gacacgttgc agctgctggt gatgaccaag
     1381 tcccgtctgg agcacgagct ggccatcaaa gccaacacct tgtgtattga caaggacaaa
     1441 tgcatgagca tgcgcaaatc cttccccagc acaccccgcc tgactggcta cacctgctct
     1501 gccatcggtt caggccctta cgccaaccac gcccctcgta tcagctccgg cccctgcagc
     1561 ggctcagcgc tttgtaaagg ccccgcctcg tgtgggggcg gggcctcttg tggaggaggg
     1621 gcctcttgcg ggggtcacgc cccttgtggc tccgcgcttt gttcccactc tgtgtcccgt
     1681 tcaggccctg gctttgcacc ggtgtgttaa atggcataac gctggaaaag gctcaaaaga
     1741 aaataaaaga gtcgttttct cccc
//
