LOCUS       NM_028056               2261 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus tubulin epsilon and delta complex 2 (Tedc2), mRNA.
ACCESSION   NM_028056 XM_128548
VERSION     NM_028056.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2261)
  AUTHORS   Breslow,D.K., Hoogendoorn,S., Kopp,A.R., Morgens,D.W., Vu,B.K.,
            Kennedy,M.C., Han,K., Li,A., Hess,G.T., Bassik,M.C., Chen,J.K. and
            Nachury,M.V.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005395.1 and BC072612.1.
            
            On Oct 12, 2017 this sequence version replaced NM_028056.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072612.1, AK146539.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AK005395.1         1-82
            83-2261             BC072612.1         1-2179
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.32 cM"
     gene            1..2261
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /note="tubulin epsilon and delta complex 2"
                     /db_xref="GeneID:72016"
                     /db_xref="MGI:MGI:1919266"
     exon            1..161
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..1422
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /note="uncharacterized protein C16orf59 homolog"
                     /codon_start=1
                     /product="tubulin epsilon and delta complex protein 2"
                     /protein_id="NP_082332.1"
                     /db_xref="CCDS:CCDS28479.1"
                     /db_xref="GeneID:72016"
                     /db_xref="MGI:MGI:1919266"
                     /translation="MLGVKGNYLLPADCAHRLVAELQGALDSCADRQRQLERSLRVSR
                     RLLQVWEPARTPSPVPETKEEDPSPACAPSSQDLEELELLTQALEKAVRVRKGVSNAG
                     QRDRTPTLTSKAATSGAAAASHPRAPSRGGSRVLGTRSTKGIQRATAPPKDYPEHRLR
                     SKGDKTHVRTQDQTTGYGPDLRDQQMTPSSAHHTTELFALKEKGTLLQLPEDFRKAVS
                     RNSCLWAQLNSARTNDSTDATRAAKTQFLHKLQMASGCSSHRPSATEVEAHARILRKA
                     CMLLRLRMQKELAIAPTDWMQEYRCLLTLEGLQTVVGQCLHRIQVLQAAVTEQLPGEC
                     LAETRTQASSVCGGEVDSACSPELLLYASTEELQTLATLKLQVALLHQQIHLEKVLMA
                     ELLPLINTQDPGGPPWLALCRAAYSLLCEGGERFLTVLRDDPAD"
     exon            162..260
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            261..319
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            320..722
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            723..776
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            777..870
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            871..982
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1084
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1275
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..2227
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1708..1713
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /note="hexamer: ATTATA"
     polyA_site      1735
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /note="major polyA site"
     regulatory      1994..1999
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2034
                     /gene="Tedc2"
                     /gene_synonym="1600002H07Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggattcgcgt tttggagctg gacttgcaag ctgtgctcaa gattgggtag cctacccgga
       61 agtgggcggc cttctgcccg gaaggcgcgg gactccttgg cggcggcaaa aatgcttggt
      121 gttaaaggaa actacctact acccgcagac tgcgctcacc ggctggtagc ggagctgcag
      181 ggcgccttgg actcctgcgc cgatcggcag cggcagttgg agcggagcct gcgcgtttcc
      241 aggaggctgc tgcaggtctg ggaaccagcc aggaccccat ctccagttcc agaaaccaaa
      301 gaagaggacc caagtccagc atgtgcaccg agttctcaag atctcgagga gctggaactt
      361 ttgacccagg ctctggagaa ggctgtacgt gtgaggaaag gcgtgtccaa tgctggacaa
      421 agagacagaa cccccactct gacatctaag gcagccactt ctggtgccgc tgccgcctcc
      481 catcctcggg ctcccagccg gggtggcagc cgtgtattgg gtacaagatc caccaagggt
      541 atacagcggg ccacagcccc tcccaaggat taccctgagc acagactacg atcaaagggt
      601 gataagaccc atgtaagaac acaagaccaa actactgggt atggaccaga cctcagggac
      661 caacaaatga ccccgtcatc tgctcatcac accacagaac tcttcgcatt aaaggagaag
      721 gggactctcc tgcagctacc tgaggacttc aggaaggcag tgtctcggaa ttcctgcctg
      781 tgggcccagc tcaactctgc acgaaccaac gactccacag atgccactag agccgccaaa
      841 actcagttcc tccacaaact ccagatggct tcaggctgtt ccagccacag gcccagtgct
      901 acagaggtgg aggcgcacgc acggatcctg aggaaggcct gtatgctgct gagacttcgt
      961 atgcaaaagg aacttgcaat agctcccact gactggatgc aggagtaccg atgcctgctc
     1021 accctggaag gactgcagac cgttgtagga cagtgtctcc acaggataca ggtgctgcaa
     1081 gcagctgtga cagagcaact tccaggagaa tgccttgcag agacgcgcac tcaggcctcg
     1141 tccgtttgcg gaggagaggt ggactctgcc tgcagccctg agctccttct ctatgctagc
     1201 accgaggagc tgcagacctt ggccaccttg aagcttcagg tggccttgct acaccagcag
     1261 atccatctag aaaaggttct gatggctgaa ctcctccctc tgataaacac ccaggatcct
     1321 ggaggaccgc cttggctggc cttgtgtcgg gctgcgtaca gtctgctctg tgagggaggc
     1381 gaacgcttcc tcacagtcct tcgagatgac cctgctgact aagcagtctg ggcaaacaag
     1441 cctctgtggg agagccccct cctctcttct ggactgtagt gaacagggat tgagggagat
     1501 tttccagttt gggggagcta taacctcacc gagaaagctg cgtggccagg gtgctccccc
     1561 tccccccaag ctcttcttag acttcttagt caggctcagc tttctgcctt cctgggggag
     1621 tccttggctg cctctacttt ctctcactct agacctccag actacctgta tgacactaga
     1681 actcctttag gaagtgtaag tatttaaatt atatcatagc agggtttggt aagcagcttt
     1741 ttggtttctt gtttctttct ttgtggtttt aagaattgta tcgattacct aggtgggagg
     1801 cagaggctgg tgattctgtg agttcaaagc cagcttgatc tacagagcaa gccaggacca
     1861 caaagagaaa ccctgtctca aaaaccaaaa tgaaaagact tgtatcaatt aaggggtttg
     1921 gagtgcctgc aatcccacag gggaggctga aggaagagta tcctaagttt aaggccagcc
     1981 tgaactctgt ttaaataaaa aaggaagggg tttaccaata aaaattcaaa agtatgagct
     2041 ggagagatgg cttgacggtt aagagtactg actgctcttc caggggtcct gagtacaatt
     2101 ctcagcaacc acatggtggc tcataaccat ctttaatggg atctgatgcc ctcttctggt
     2161 gtgtctgaag acagctacag tatatttata tacataaaat aaataaacct tttttaaaaa
     2221 ttcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
