LOCUS       NM_009348               2884 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus tectorin beta (Tectb), mRNA.
ACCESSION   NM_009348
VERSION     NM_009348.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2884)
  AUTHORS   Xie,Z., Ma,X.H., Bai,Q.F., Tang,J., Sun,J.H., Jiang,F., Guo,W.,
            Wang,C.M., Yang,R., Wen,Y.C., Wang,F.Y., Chen,Y.X., Zhang,H.,
            He,D.Z., Kelley,M.W., Yang,S. and Zhang,W.J.
  TITLE     ZBTB20 is essential for cochlear maturation and hearing in mice
  JOURNAL   Proc Natl Acad Sci U S A 120 (24), e2220867120 (2023)
   PUBMED   37279265
REFERENCE   2  (bases 1 to 2884)
  AUTHORS   Ebeid,M., Barnas,K., Zhang,H., Yaghmour,A., Noreikaite,G. and
            Bjork,B.C.
  TITLE     PRDM16 expression and function in mammalian cochlear development
  JOURNAL   Dev Dyn 251 (10), 1666-1683 (2022)
   PUBMED   35451126
REFERENCE   3  (bases 1 to 2884)
  AUTHORS   Yang,L.M., Stout,L., Rauchman,M. and Ornitz,D.M.
  TITLE     Analysis of FGF20-regulated genes in organ of Corti progenitors by
            translating ribosome affinity purification
  JOURNAL   Dev Dyn 249 (10), 1217-1242 (2020)
   PUBMED   32492250
REFERENCE   4  (bases 1 to 2884)
  AUTHORS   Ono,K., Sandell,L.L., Trainor,P.A. and Wu,D.K.
  TITLE     Retinoic acid synthesis and autoregulation mediate zonal patterning
            of vestibular organs and inner ear morphogenesis
  JOURNAL   Development 147 (15) (2020)
   PUBMED   32665247
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2884)
  AUTHORS   Ono,K., Keller,J., Lopez Ramirez,O., Gonzalez Garrido,A.,
            Zobeiri,O.A., Chang,H.H.V., Vijayakumar,S., Ayiotis,A., Duester,G.,
            Della Santina,C.C., Jones,S.M., Cullen,K.E., Eatock,R.A. and
            Wu,D.K.
  TITLE     Retinoic acid degradation shapes zonal development of vestibular
            organs and sensitivity to transient linear accelerations
  JOURNAL   Nat Commun 11 (1), 63 (2020)
   PUBMED   31896743
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2884)
  AUTHORS   Coghill,E.L., Hugill,A., Parkinson,N., Davison,C., Glenister,P.,
            Clements,S., Hunter,J., Cox,R.D. and Brown,S.D.
  TITLE     A gene-driven approach to the identification of ENU mutants in the
            mouse
  JOURNAL   Nat Genet 30 (3), 255-256 (2002)
   PUBMED   11850622
REFERENCE   7  (bases 1 to 2884)
  AUTHORS   Suriyapperuma,S.P., Lozovatsky,L., Ciciotte,S.L., Peters,L.L. and
            Gilligan,D.M.
  TITLE     The mouse adducin gene family: alternative splicing and chromosomal
            localization
  JOURNAL   Mamm Genome 11 (1), 16-23 (2000)
   PUBMED   10602987
REFERENCE   8  (bases 1 to 2884)
  AUTHORS   Rau,A., Legan,P.K. and Richardson,G.P.
  TITLE     Tectorin mRNA expression is spatially and temporally restricted
            during mouse inner ear development
  JOURNAL   J Comp Neurol 405 (2), 271-280 (1999)
   PUBMED   10023815
REFERENCE   9  (bases 1 to 2884)
  AUTHORS   Kim,H.J., Noben-Trauth,K. and Morell,R.J.
  TITLE     Tectorin-beta (Tectb) maps to mouse chromosome 19
  JOURNAL   Genomics 53 (3), 419-420 (1998)
   PUBMED   9799617
REFERENCE   10 (bases 1 to 2884)
  AUTHORS   Legan,P.K., Rau,A., Keen,J.N. and Richardson,G.P.
  TITLE     The mouse tectorins. Modular matrix proteins of the inner ear
            homologous to components of the sperm-egg adhesion system
  JOURNAL   J Biol Chem 272 (13), 8791-8801 (1997)
   PUBMED   9079715
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110206.21.
            
            On Feb 1, 2019 this sequence version replaced NM_009348.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X99806.2, BC138889.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-365               AC110206.21        180151-180515
            366-556             AC110206.21        181220-181410
            557-699             AC110206.21        183142-183284
            700-772             AC110206.21        183388-183460
            773-876             AC110206.21        188987-189090
            877-960             AC110206.21        189213-189296
            961-1123            AC110206.21        190850-191012
            1124-1196           AC110206.21        191989-192061
            1197-1229           AC110206.21        193265-193297
            1230-2884           AC110206.21        194084-195738
FEATURES             Location/Qualifiers
     source          1..2884
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 51.13 cM"
     gene            1..2884
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /note="tectorin beta"
                     /db_xref="GeneID:21684"
                     /db_xref="MGI:MGI:109574"
     exon            1..365
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     CDS             290..1279
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /note="beta-tectorin; [b]-tectorin"
                     /codon_start=1
                     /product="beta-tectorin precursor"
                     /protein_id="NP_033374.2"
                     /db_xref="CCDS:CCDS29907.1"
                     /db_xref="GeneID:21684"
                     /db_xref="MGI:MGI:109574"
                     /translation="MVVRAFVLLALFAEASAKSCTPNKADVILVFCYPKTIITKIPEC
                     PYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIV
                     SNDSTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQRVATVHVKNGSMGTFESQLSLNFY
                     TNAKFSTKKEAPFVLETSEIGSDLFAGVEAKGLSVRFKVVLNSCWATPSADFMYPLQW
                     QLINKGCPTDETVLVHENGKDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSC
                     PVNCDKRKRMLRDQTGGVLVVELSLRSRAFSGLCDFSDVLLHLILMLGTWAVL"
     exon            366..556
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            557..699
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            700..772
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            773..876
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            877..960
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1123
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1196
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1229
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..2884
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2855..2860
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /note="hexamer: AATAAA"
     polyA_site      2884
                     /gene="Tectb"
                     /gene_synonym="Tctnb"
                     /note="major polyA site"
ORIGIN      
        1 ggggagcttc cgggaggcag catctgcagt ccagagagaa tgagaaaggc aggaacatga
       61 gccaccgcct gtgacactca catcctcagt ggtacaagct caggacagca tcaccgagct
      121 ctcttggaaa ctcccccaca agattgtatg ataatttgtt ctaacccttg actgtaactt
      181 ttccttcata tttccgatac agaacaaccg cgacccgggg cctggaagga gcgtgagcat
      241 tgagccagtt tggtttggcc acctggcaga gatcgactct agaggagcga tggtggtcag
      301 ggccttcgtt ttgctggccc tctttgcaga agcctcagcg aaatcatgca ctccgaataa
      361 agcagatgtc atccttgtgt tttgttatcc caagaccatc atcactaaaa tccccgagtg
      421 tccctatgga tgggaagtac accagctggc actcgggggg ctgtgttaca acggggtcca
      481 tgaaggtggc tattaccagt ttgtcatccc tgatctgtca cctaagaaca agtcctactg
      541 tggaacccag tcagagtaca agccccccat ctaccacttc tacagccaca tcgtgtccaa
      601 cgacagcaca gtgatcgtga agaaccagcc cgtcaactac tccttctcct gcacctacca
      661 ctccacctac ttggtgaacc aggctgcttt tgaccagaga gtggccactg ttcacgtcaa
      721 gaacgggagc atgggcacat ttgaaagcca gttgtccctc aacttctaca ctaatgccaa
      781 gttttccacc aaaaaagaag ctcccttcgt tctggaaacg tccgaaatcg gctcagatct
      841 gtttgcggga gtagaagcca aaggcctaag cgttcggttc aaagtggtct tgaatagctg
      901 ctgggccacc ccctcggctg acttcatgta ccccttacag tggcagctca tcaataaggg
      961 ctgccccacc gatgagacag tcctcgtgca tgagaacggc aaagaccaca gggccacttt
     1021 ccaattcaat gccttccggt tccagaacat ccccaaactt tccaaggttt ggttacactg
     1081 tgagacgttc atctgcgaca gtgagaagct ctcctgcccc gtgaactgtg acaaacggaa
     1141 gcgcatgcta cgtgaccaga caggaggtgt cctggttgtg gagttgtccc tgaggagcag
     1201 ggcattttcc ggcctctgtg acttctcaga tgttcttctt cacctcatcc tgatgctggg
     1261 gacctgggct gtgttgtagg agacagctgg acagctgtag cagctctctc caaggccacc
     1321 ctgaactatg acacattcgt ttattgtgct gccaaaaaaa gaacagacag aagactgcat
     1381 ggctggggag ctgggaacag ccctttgcca aatatgtgtt cccccatgtt tgtgtgtgga
     1441 tgtgaatttg gtgaacctct gcctcagagc cacacttcca cttattccgt cctgcggccg
     1501 ttagatcctg ataatcttct ccatgaagcc agagaggagt gttctctcct ccgctcaaat
     1561 tagagcagca tttggaagct actttcatta taaaagactc tcacacactc atcacatgca
     1621 gcttaacatt tggaggcaga gacagacaaa caccaaaaaa aaaaaatcaa tgccaaatac
     1681 agaatccaca ggaatagcca actttaccca gcaggcactc tgtcattgag acagtacagt
     1741 tctaaggacc agcatcgagc ccccaggcag gaagttccag tcttcaacca cgatgtggaa
     1801 gtccaagtta aatacaatat atttactcaa acttctgtaa tggatgagaa ggggatcctt
     1861 gagagccgct agtaccagtc tgcttttatc atagggtttc ttaaatagat ataatcatta
     1921 gggaggtata gatgtcttat ccttacaaga gattctattt ctttagtcac aaataaatag
     1981 gaaatcgact atgaacaagt aaaactcatc tccatttcac agaagagtgt ggcattgcct
     2041 ccgtgaactg tatttgcacg ggagtggaaa gactctggcc gagccggttc tctgagaggt
     2101 gagagccgag cttccctcac acctgtggtg ccctgtgcgt tcaatagcct agtgtgtgct
     2161 cttggaagtc ttcctgtcag gatggtggga tgcgaacatc caagccctgt tccttcttgg
     2221 tcacttgtga ctgtggggac tgaaccatcc actcatcaga aatgtaatgc atacacagtc
     2281 aatgacatca catgacagca cactctcaga actggccacc cctgtgaccc agagcatgcc
     2341 aacgtccgta ggtcacattt ggcaatgaga agccaagtga acacaccaat cctgtgagag
     2401 catgagctgt ggtatgacag gagagacctt gtgctaagtc tttttttttc ccctttgtca
     2461 ctttcacact gggcatttga aatcacatat cagtttgtcc ctctgtattt catgcccttg
     2521 agaggtcttg atgtctgtgg tttaccaatc cttttacaac ttgggtaaat gaacttagaa
     2581 attgtgtttg tttagccgca ggctagtgca cggtggtccc atgtattcta aacttggtat
     2641 ctagttcatg ctccaatcag tttggaacca cttcctaatg taacgtcaga gtttgttgta
     2701 gctgagaatt acagaaaacc tgctttcttg atcctagtca ggaactctta cgaagcacac
     2761 atatagccaa gcttataggt ctttggctgt cagactaaaa acaatgtttg atcctgatgt
     2821 atggtcttgt atctcaacct ggtgctatgg actaaataaa atgtctggag taagtaacct
     2881 gtga
//
